Martin T Swain
Affiliation: University of Wales
Dudek M, Adams J, Swain M, Hegarty M, Huws S, Gallagher J. Metaphylogenomic and potential functionality of the limpet Patella pellucida's gastrointestinal tract microbiome. Int J Mol Sci. 2014;15:18819-39 pubmed publisher
Hargreaves A, Swain M, Logan D, Mulley J. Testing the Toxicofera: comparative transcriptomics casts doubt on the single, early evolution of the reptile venom system. Toxicon. 2014;92:140-56 pubmed publisher
..The apparent conservation of gene complements across the Toxicofera therefore reflects an artefact of incomplete tissue sampling. We therefore conclude that venom has evolved multiple times in reptiles. ..
Geyer K, Munshi S, Vickers M, Squance M, Wilkinson T, Berrar D, et al
. The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities. Int J Parasitol Drugs Drug Resist. 2018;8:213-222 pubmed publisher
..This study demonstrates that the anti-fecundity activity of 5-AzaC affects more than just DNA methylation in schistosome parasites. Further characterisation of these processes may reveal novel targets for schistosomiasis control. ..
Hadfield S, Pachebat J, Swain M, Robinson G, Cameron S, Alexander J, et al
. Generation of whole genome sequences of new Cryptosporidium hominis and Cryptosporidium parvum isolates directly from stool samples. BMC Genomics. 2015;16:650 pubmed publisher
..This represents the first report of high-quality whole genome sequencing of Cryptosporidium isolates prepared directly from human stool samples. ..
Kara A, Vickers M, Swain M, Whitworth D, Fernandez Fuentes N. Genome-wide prediction of prokaryotic two-component system networks using a sequence-based meta-predictor. BMC Bioinformatics. 2015;16:297 pubmed publisher
..MetaPred2CS outperformed other available systems in our benchmark tests, and is available online at http://metapred2cs.ibers.aber.ac.uk, along with our gold standard dataset of TCS interaction pairs. ..
Niazi U, Geyer K, Vickers M, Hoffmann K, Swain M. DISMISS: detection of stranded methylation in MeDIP-Seq data. BMC Bioinformatics. 2016;17:295 pubmed publisher
Mulley J, Hargreaves A, Hegarty M, Heller R, Swain M. Transcriptomic analysis of the lesser spotted catshark (Scyliorhinus canicula) pancreas, liver and brain reveals molecular level conservation of vertebrate pancreas function. BMC Genomics. 2014;15:1074 pubmed publisher