Kim M Summers

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Dogslife: a web-based longitudinal study of Labrador Retriever health in the UK
    Dylan N Clements
    Royal Dick School of Veterinary Studies, University of Edinburgh, Rosli, Scotland
    BMC Vet Res 9:13. 2013
  2. ncbi request reprint Recent developments in the diagnosis of Marfan syndrome and related disorders
    Kim M Summers
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Edinburgh, UK
    Med J Aust 197:494-7. 2012
  3. pmc Anterior segment mesenchymal dysgenesis in a large Australian family is associated with the recurrent 17 bp duplication in PITX3
    Kim M Summers
    Roslin Institute, University of Edinburgh, Roslin, Midlothian, UK
    Mol Vis 14:2010-5. 2008
  4. doi request reprint Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1
    Kim M Summers
    The University of Edinburgh, The Roslin Institute and Royal Dick School of Veterinary Studies, Roslin, Midlothian EH25 9PS, UK
    Genomics 94:233-40. 2009
  5. pmc Co-expression of FBN1 with mesenchyme-specific genes in mouse cell lines: implications for phenotypic variability in Marfan syndrome
    Kim M Summers
    The Roslin Institute, University of Edinburgh, Midlothian, UK
    Eur J Hum Genet 18:1209-15. 2010
  6. doi request reprint Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations
    David A Hume
    The Roslin Institute, Roslin Biocentre, Roslin, Midlothian, UK
    Genomics 95:328-38. 2010
  7. doi request reprint Population structure and genetic heterogeneity in popular dog breeds in the UK
    Richard J Mellanby
    Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK
    Vet J 196:92-7. 2013
  8. pmc A gene expression atlas of the domestic pig
    Tom C Freeman
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush, EH25 9PS, UK
    BMC Biol 10:90. 2012
  9. doi request reprint Mutations at KCNQ1 and an unknown locus cause long QT syndrome in a large Australian family: implications for genetic testing
    Kim M Summers
    The Roslin Institute and Royal Dick School of Veterinary Studies, The University of Edinburgh, Midlothian, Scotland, UK
    Am J Med Genet A 152:613-21. 2010
  10. pmc Transcriptional profiling of the human fibrillin/LTBP gene family, key regulators of mesenchymal cell functions
    Margaret R Davis
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush EH25 9RG, UK Electronic address
    Mol Genet Metab 112:73-83. 2014

Detail Information

Publications13

  1. pmc Dogslife: a web-based longitudinal study of Labrador Retriever health in the UK
    Dylan N Clements
    Royal Dick School of Veterinary Studies, University of Edinburgh, Rosli, Scotland
    BMC Vet Res 9:13. 2013
    ..The study has been designed to examine how environmental and genetic factors influence the health and development of a birth cohort of UK-based pedigree Labrador Retrievers...
  2. ncbi request reprint Recent developments in the diagnosis of Marfan syndrome and related disorders
    Kim M Summers
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Edinburgh, UK
    Med J Aust 197:494-7. 2012
    ..Several clinical trials of drug therapy, including the antihypertensive drug losartan, are in progress...
  3. pmc Anterior segment mesenchymal dysgenesis in a large Australian family is associated with the recurrent 17 bp duplication in PITX3
    Kim M Summers
    Roslin Institute, University of Edinburgh, Roslin, Midlothian, UK
    Mol Vis 14:2010-5. 2008
    ..This study reports the examination of PITX3 in this Australian family...
  4. doi request reprint Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1
    Kim M Summers
    The University of Edinburgh, The Roslin Institute and Royal Dick School of Veterinary Studies, Roslin, Midlothian EH25 9PS, UK
    Genomics 94:233-40. 2009
    ..Understanding the regulation of the FBN1 gene may lead to alternative therapeutic strategies for Marfan syndrome...
  5. pmc Co-expression of FBN1 with mesenchyme-specific genes in mouse cell lines: implications for phenotypic variability in Marfan syndrome
    Kim M Summers
    The Roslin Institute, University of Edinburgh, Midlothian, UK
    Eur J Hum Genet 18:1209-15. 2010
    ..Promoter analysis of this gene set identified several candidate transcriptional regulators. Genes within this co-expressed cluster are candidate genetic modifiers for Marfan syndrome and for other connective tissue diseases...
  6. doi request reprint Functional clustering and lineage markers: insights into cellular differentiation and gene function from large-scale microarray studies of purified primary cell populations
    David A Hume
    The Roslin Institute, Roslin Biocentre, Roslin, Midlothian, UK
    Genomics 95:328-38. 2010
    ..We discuss the limitations placed upon such data by the presence of alternative promoters with distinct tissue specificity within many protein-coding genes...
  7. doi request reprint Population structure and genetic heterogeneity in popular dog breeds in the UK
    Richard J Mellanby
    Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian EH25 9RG, UK
    Vet J 196:92-7. 2013
    ..The least distinct group contained crossbred dogs. The results show that the registered breeds are subject to a 'breed barrier' which promotes reduction in genetic diversity...
  8. pmc A gene expression atlas of the domestic pig
    Tom C Freeman
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush, EH25 9PS, UK
    BMC Biol 10:90. 2012
    ..The new array was used to generate a genome-wide expression atlas of pig tissues derived from 62 tissue/cell types. These data were subjected to network correlation analysis and clustering...
  9. doi request reprint Mutations at KCNQ1 and an unknown locus cause long QT syndrome in a large Australian family: implications for genetic testing
    Kim M Summers
    The Roslin Institute and Royal Dick School of Veterinary Studies, The University of Edinburgh, Midlothian, Scotland, UK
    Am J Med Genet A 152:613-21. 2010
    ....
  10. pmc Transcriptional profiling of the human fibrillin/LTBP gene family, key regulators of mesenchymal cell functions
    Margaret R Davis
    The Roslin Institute and Royal Dick School of Veterinary Studies, University of Edinburgh, Easter Bush EH25 9RG, UK Electronic address
    Mol Genet Metab 112:73-83. 2014
    ....
  11. doi request reprint Structure and function of the mammalian fibrillin gene family: implications for human connective tissue diseases
    Margaret R Davis
    The Roslin Institute and Royal Dick School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK
    Mol Genet Metab 107:635-47. 2012
    ....
  12. pmc Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations
    Neil A Mabbott
    The Roslin Institute and Royal Dick School of Veterinary Sciences, University of Edinburgh, Easter Bush, Midlothian, UK
    Immunology 133:482-98. 2011
    ..Together, these data suggest FDC are a specialized mesenchymal cell population within the germinal centres of lymphoid tissues...
  13. doi request reprint Genome-wide analysis of mitral valve disease in Cavalier King Charles Spaniels
    Anne T French
    Royal Dick School of Veterinary Studies, The University of Edinburgh, Easter Bush, Roslin, Midlothian EH25 9RG, UK
    Vet J 193:283-6. 2012
    ....