Cathie L M Sudlow

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Are lacunar strokes really different? A systematic review of differences in risk factor profiles between lacunar and nonlacunar infarcts
    Caroline Jackson
    Division of Clinical Neurosciences, University of Edinburgh, United Kingdom
    Stroke 36:891-901. 2005
  2. pmc Does apolipoprotein E genotype influence the risk of ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage? Systematic review and meta-analyses of 31 studies among 5961 cases and 17,965 controls
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, United Kingdom
    Stroke 37:364-70. 2006
  3. pmc Dipyridamole with aspirin is better than aspirin alone in preventing vascular events after ischaemic stroke or TIA
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU
    BMJ 334:901. 2007
  4. pmc Improving adherence to medication in stroke survivors (IAMSS): a randomised controlled trial: study protocol
    Ronan O'Carroll
    Department of Psychology, Stirling University, Stirling, UK
    BMC Neurol 10:15. 2010
  5. doi Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome"
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Science 328:825; author reply 825. 2010
  6. doi Preventing further vascular events after a stroke or transient ischaemic attack: an update on medical management
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Pract Neurol 8:141-57. 2008
  7. pmc APOE associations with severe CAA-associated vasculopathic changes: collaborative meta-analysis
    Kristiina Rannikmäe
    Division of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 85:300-5. 2014
  8. doi Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects
    Lavinia Paternoster
    Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom
    Circ Cardiovasc Genet 3:15-21. 2010
  9. pmc Lack of association of white matter lesions with ipsilateral carotid artery stenosis
    Gillian M Potter
    Division of Clinical Neurosciences, Brain Research Imaging Centre, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 33:378-84. 2012
  10. doi Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review
    Emma L Bailey
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Int J Stroke 6:434-44. 2011

Collaborators

Detail Information

Publications32

  1. pmc Are lacunar strokes really different? A systematic review of differences in risk factor profiles between lacunar and nonlacunar infarcts
    Caroline Jackson
    Division of Clinical Neurosciences, University of Edinburgh, United Kingdom
    Stroke 36:891-901. 2005
    ..Differences in risk factors between lacunar and nonlacunar infarcts might support a distinct arterial pathological process underlying lacunar infarction...
  2. pmc Does apolipoprotein E genotype influence the risk of ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage? Systematic review and meta-analyses of 31 studies among 5961 cases and 17,965 controls
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, United Kingdom
    Stroke 37:364-70. 2006
    ..Apolipoprotein E genotype (APOE) is associated with cholesterol metabolism, ischemic heart disease, and cerebral amyloid angiopathy, and so may affect risk of both ischemic and hemorrhagic stroke...
  3. pmc Dipyridamole with aspirin is better than aspirin alone in preventing vascular events after ischaemic stroke or TIA
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU
    BMJ 334:901. 2007
  4. pmc Improving adherence to medication in stroke survivors (IAMSS): a randomised controlled trial: study protocol
    Ronan O'Carroll
    Department of Psychology, Stirling University, Stirling, UK
    BMC Neurol 10:15. 2010
    ..We now wish to pilot a brief intervention aimed at (a) helping patients establish a better medication-taking routine, and (b) eliciting and modifying any erroneous beliefs regarding their medication and their stroke...
  5. doi Comment on "Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome"
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Science 328:825; author reply 825. 2010
    ..If real, the association may lack generalizability because of the specific characteristics of the cases studied and could be due to reverse causality...
  6. doi Preventing further vascular events after a stroke or transient ischaemic attack: an update on medical management
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Pract Neurol 8:141-57. 2008
    ..Lifestyle changes (for example, stopping smoking, reducing excess alcohol intake, adopting a healthy diet) and careful management of diabetes are also important...
  7. pmc APOE associations with severe CAA-associated vasculopathic changes: collaborative meta-analysis
    Kristiina Rannikmäe
    Division of Clinical Neurosciences, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 85:300-5. 2014
    ..We assessed the evidence for these allele-specific effects...
  8. doi Genetic effects on carotid intima-media thickness: systematic assessment and meta-analyses of candidate gene polymorphisms studied in more than 5000 subjects
    Lavinia Paternoster
    Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, United Kingdom
    Circ Cardiovasc Genet 3:15-21. 2010
    ..There have been many CIMT candidate gene association studies, but no systematic review to identify consistent, reliable findings...
  9. pmc Lack of association of white matter lesions with ipsilateral carotid artery stenosis
    Gillian M Potter
    Division of Clinical Neurosciences, Brain Research Imaging Centre, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 33:378-84. 2012
    ..A role for carotid artery atherothromboemboli has been suggested. If this is the case, more WML would be expected ipsilateral to increasing degrees of carotid stenosis...
  10. doi Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review
    Emma L Bailey
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Int J Stroke 6:434-44. 2011
    ..Further studies should focus on structural changes at early ages and genetics to identify factors that predispose to vascular and brain damage...
  11. doi Differing risk factor profiles of ischemic stroke subtypes: evidence for a distinct lacunar arteriopathy?
    Caroline A Jackson
    Division of Clinical Neurosciences, University of Edinburgh, United Kingdom
    Stroke 41:624-9. 2010
    ..We overcame these by pooling individual data on 2875 patients with first-ever ischemic stroke from 5 collaborating prospective stroke registers that used similar, unbiased methods to define risk factors and classify stroke subtypes...
  12. doi Differences between ischemic stroke subtypes in vascular outcomes support a distinct lacunar ischemic stroke arteriopathy: a prospective, hospital-based study
    Caroline A Jackson
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU
    Stroke 40:3679-84. 2009
    ..Different risks of recurrent stroke and MI after lacunar versus nonlacunar ischemic stroke may support a distinct lacunar arteriopathy...
  13. doi Pathology of lacunar ischemic stroke in humans--a systematic review
    Emma L Bailey
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Brain Pathol 22:583-91. 2012
    ..Standardised pathological definitions based on well-characterized post-mortem derived material supported by detailed clinical and imaging data are needed...
  14. ncbi Epilepsy and stroke
    Cathie L M Sudlow
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK
    Lancet 363:1175-6. 2004
  15. pmc Problems with UK government's risk sharing scheme for assessing drugs for multiple sclerosis
    Cathie L M Sudlow
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU
    BMJ 326:388-92. 2003
  16. pmc US guidelines on neuroimaging in patients with non-acute headache: a commentary
    Cathie Sudlow
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, UK
    J Neurol Neurosurg Psychiatry 72:ii16-ii18. 2002
  17. pmc Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6
    William Whiteley
    Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Med 6:e1000145. 2009
    ....
  18. ncbi Stroke
    Charles Warlow
    Division of Clinical Neurosciences, Western General Hospital, EH4 2XU, Edinburgh, UK
    Lancet 362:1211-24. 2003
    ..However, stroke management will only be most effective when delivered in the context of an organised, expert, educated, and enthusiastic stroke service that can react quickly to the needs of patients at all stages from onset to recovery...
  19. ncbi Lacunar stroke is associated with diffuse blood-brain barrier dysfunction
    Joanna M Wardlaw
    University of Edinburgh, United Kingdom
    Ann Neurol 65:194-202. 2009
    ..We tested for subtle generalized BBB leakiness in patients with lacunar stroke and control patients with cortical ischemic stroke...
  20. pmc Association of circulating inflammatory markers with recurrent vascular events after stroke: a prospective cohort study
    William Whiteley
    Department of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, UK
    Stroke 42:10-6. 2011
    ....
  21. pmc Associations of clinical stroke misclassification ('clinical-imaging dissociation') in acute ischemic stroke
    Gillian Potter
    Department of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Cerebrovasc Dis 29:395-402. 2010
    ..The reasons for this discrepancy are unclear. We assessed clinical and imaging features which might explain this 'clinical-imaging dissociation' (C-ID)...
  22. pmc Epidemiology of stroke and its subtypes in Chinese vs white populations: a systematic review
    Chung Fen Tsai
    Division of Clinical Neurosciences, University of Edinburgh, UK
    Neurology 81:264-72. 2013
    ..We aimed to systematically assess the evidence for differences in the incidence of stroke and distribution of its subtypes in Chinese compared with white populations...
  23. doi Genetic determinants of white matter hyperintensities on brain scans: a systematic assessment of 19 candidate gene polymorphisms in 46 studies in 19,000 subjects
    Lavinia Paternoster
    Division of Clinical Neurosciences, University of Edinburgh, Scotland, UK
    Stroke 40:2020-6. 2009
    ..Many studies have attempted to find associations between polymorphisms in various candidate genes and WMH. We aimed to evaluate the evidence for these associations by performing a systematic review and series of meta-analyses...
  24. doi improving interrater agreement about brain microbleeds: development of the Brain Observer MicroBleed Scale (BOMBS)
    Charlotte Cordonnier
    Division of Clinical Neurosciences, Western General Hospital, Edinburgh EH4 2XU, UK
    Stroke 40:94-9. 2009
    ..If the diagnostic and prognostic significance of brain microbleeds (BMBs) are to be investigated and used for these purposes in clinical practice, observer variation in BMB assessment must be minimized...
  25. pmc What is the role of dipyridamole in long-term secondary prevention after an ischemic stroke or transient ischemic attack?
    Cathie Sudlow
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, Scotland
    CMAJ 173:1024-6. 2005
  26. doi Genetics of cerebral amyloid angiopathy: systematic review and meta-analysis
    Kristiina Rannikmäe
    Division of Clinical Neurosciences, University of Edinburgh, Western General Hospital, Edinburgh, UK
    J Neurol Neurosurg Psychiatry 84:901-8. 2013
    ..Cerebral amyloid angiopathy (CAA) is common in the ageing brain and is associated with dementia and lobar intracerebral haemorrhage. We systematically reviewed genetic associations with CAA to better understand its pathogenesis...
  27. pmc Association between apolipoprotein E genotype and carotid intima-media thickness may suggest a specific effect on large artery atherothrombotic stroke
    Lavinia Paternoster
    Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK
    Stroke 39:48-54. 2008
    ..We therefore performed a systematic review and meta-analysis of the association between APOE and CIMT...
  28. pmc Comparing risks of death and recurrent vascular events between lacunar and non-lacunar infarction
    Caroline Jackson
    Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, UK
    Brain 128:2507-17. 2005
    ..There is some evidence that recurrent ischaemic stroke subtypes breed true. These results provide limited support for a distinct arterial pathology underlying lacunar infarction...
  29. doi Potential animal models of lacunar stroke: a systematic review
    Emma L Bailey
    Division of Clinical Neurosciences, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK
    Stroke 40:e451-8. 2009
    ..Models of any of these pathological features would aid understanding of the etiology and help develop treatments for lacunar stroke. We therefore aimed to assess the relevance of all available potential animal models of lacunar stroke...
  30. pmc Genetic associations with brain microbleeds: Systematic review and meta-analyses
    S S Maxwell
    Medical School, Division of Clinical Neurosciences, University of Edinburgh, Edinburgh, EH4 2XU, UK
    Neurology 77:158-67. 2011
    ..We performed a systematic review and meta-analyses to assess the evidence for genetic associations with brain microbleeds (BMBs)...
  31. pmc Antiplatelet therapy and atherosclerotic events. Commentary is inaccurate
    Cathie Sudlow
    BMJ 324:917. 2002
  32. ncbi [Stroke: secondary prevention]
    Gord Gubitz
    Vasa 33:110-3; discussion 114. 2004