David J Stott

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. ncbi request reprint Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease
    David J Stott
    Division of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom
    Am J Clin Nutr 82:1320-6. 2005
  2. doi request reprint Activation of hemostasis and decline in cognitive function in older people
    David J Stott
    Academic Section of Geriatric Medicine, 3 Floor Queen Elizabeth Building, Royal Infirmary, Glasgow G31 2ER
    Arterioscler Thromb Vasc Biol 30:605-11. 2010
  3. ncbi request reprint Adipocytokines and risk of stroke in older people: a nested case-control study
    David J Stott
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Scotland, UK
    Int J Epidemiol 38:253-61. 2009
  4. ncbi request reprint Comprehensive geriatric assessment and home-based rehabilitation for elderly people with a history of recurrent non-elective hospital admissions
    David J Stott
    Department of Medicine for the Elderly, Glasgow Royal Infirmary, Glasgow G4 0SF, UK
    Age Ageing 35:487-91. 2006
  5. ncbi request reprint Blood pressure in very elderly people
    David J Stott
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary, Glasgow, UK
    J Hypertens 24:263-4. 2006
  6. doi request reprint Multidisciplinary care for elderly people in the community
    David J Stott
    Academic Section of Geriatric Medicine, University of Glasgow Faculty of Medicine, Glasgow Royal Infirmary, Glasgow G31 2ER, UK
    Lancet 371:699-700. 2008
  7. doi request reprint Does low to moderate alcohol intake protect against cognitive decline in older people?
    David J Stott
    Faculty of Medicine, Academic Section of Geriatric Medicine, University of Glasgow, Glasgow, United Kingdom
    J Am Geriatr Soc 56:2217-24. 2008
  8. doi request reprint Urinary tract infection after stroke
    D J Stott
    Academic Section of Geriatric Medicine, Third Floor, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow G31 2ER, UK
    QJM 102:243-9. 2009
  9. ncbi request reprint Nosocomial transmission of influenza
    D J Stott
    Academic Section of Geriatric Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow G4 0SF, UK
    Occup Med (Lond) 52:249-53. 2002
  10. pmc Leptin predicts diabetes but not cardiovascular disease: results from a large prospective study in an elderly population
    Paul Welsh
    Faculty of Medicine, University of Glasgow, Scotland, UK
    Diabetes Care 32:308-10. 2009

Detail Information

Publications52

  1. ncbi request reprint Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease
    David J Stott
    Division of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom
    Am J Clin Nutr 82:1320-6. 2005
    ..Homocysteine is an independent risk factor for vascular disease and is associated with dementia in older people. Potential mechanisms include altered endothelial and hemostatic function...
  2. doi request reprint Activation of hemostasis and decline in cognitive function in older people
    David J Stott
    Academic Section of Geriatric Medicine, 3 Floor Queen Elizabeth Building, Royal Infirmary, Glasgow G31 2ER
    Arterioscler Thromb Vasc Biol 30:605-11. 2010
    ..To determine whether activation of hemostatic function (thrombosis and fibrinolysis) is associated with cognitive decline in older people...
  3. ncbi request reprint Adipocytokines and risk of stroke in older people: a nested case-control study
    David J Stott
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Scotland, UK
    Int J Epidemiol 38:253-61. 2009
    ..Inflammation may play an important role in atherothrombosis and in promoting cerebral damage after stroke. We hypothesized that plasma adipocytokine concentrations would be associated with risk of stroke in older people...
  4. ncbi request reprint Comprehensive geriatric assessment and home-based rehabilitation for elderly people with a history of recurrent non-elective hospital admissions
    David J Stott
    Department of Medicine for the Elderly, Glasgow Royal Infirmary, Glasgow G4 0SF, UK
    Age Ageing 35:487-91. 2006
    ..To determine whether a co-ordinated programme of geriatric assessment and multidisciplinary home-based rehabilitation reduces disability and prevents non-elective hospital readmission in high-risk elderly patients...
  5. ncbi request reprint Blood pressure in very elderly people
    David J Stott
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary, Glasgow, UK
    J Hypertens 24:263-4. 2006
  6. doi request reprint Multidisciplinary care for elderly people in the community
    David J Stott
    Academic Section of Geriatric Medicine, University of Glasgow Faculty of Medicine, Glasgow Royal Infirmary, Glasgow G31 2ER, UK
    Lancet 371:699-700. 2008
  7. doi request reprint Does low to moderate alcohol intake protect against cognitive decline in older people?
    David J Stott
    Faculty of Medicine, Academic Section of Geriatric Medicine, University of Glasgow, Glasgow, United Kingdom
    J Am Geriatr Soc 56:2217-24. 2008
    ..To determine whether low to moderate alcohol intake is protective against cognitive decline in older people...
  8. doi request reprint Urinary tract infection after stroke
    D J Stott
    Academic Section of Geriatric Medicine, Third Floor, Queen Elizabeth Building, Glasgow Royal Infirmary, Glasgow G31 2ER, UK
    QJM 102:243-9. 2009
    ..Urinary tract infection (UTI) is a recognized complication of stroke. We aimed to determine the incidence of UTI after acute stroke, the risk factors associated with this complication, and its association with outcome...
  9. ncbi request reprint Nosocomial transmission of influenza
    D J Stott
    Academic Section of Geriatric Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow G4 0SF, UK
    Occup Med (Lond) 52:249-53. 2002
    ..Vaccination of health care workers has been shown to be effective in protecting elderly patients in long-term care. Use of oral amantadine or rimantadine is an additional possible strategy for prophylaxis or treatment during an outbreak...
  10. pmc Leptin predicts diabetes but not cardiovascular disease: results from a large prospective study in an elderly population
    Paul Welsh
    Faculty of Medicine, University of Glasgow, Scotland, UK
    Diabetes Care 32:308-10. 2009
    ..To clarify the association of circulating levels of leptin with risk for cardiovascular disease (CVD) events and new-onset diabetes in men and women...
  11. doi request reprint Circulating interleukin-10 and risk of cardiovascular events: a prospective study in the elderly at risk
    Paul Welsh
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Scotland
    Arterioscler Thromb Vasc Biol 31:2338-44. 2011
    ..The goal of this study was to examine the association of the antiinflammatory interleukin-10 (IL-10) with risk of cardiovascular disease (CVD)...
  12. doi request reprint Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke
    Paul Welsh
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
    Cerebrovasc Dis 27:247-53. 2009
    ..Many inflammatory and haemostatic biomarkers show associations with acute ischaemic stroke outcome, but few studies compare a large range of markers...
  13. ncbi request reprint Association between apolipoprotein E4 and cognitive decline in elderly adults
    Chris J Packard
    Department of Vascular Biochemistry, University of Glasgow, Glasgow, Scotland
    J Am Geriatr Soc 55:1777-85. 2007
    ..To determine the influence of apolipoprotein E on cognitive decline in a cohort of elderly men and women...
  14. doi request reprint The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes
    Ian Ford
    From the Robertson Centre for Biostatistics, University of Glasgow, Glasgow, Scotland
    Int J Epidemiol 40:1530-8. 2011
    ..High serum alanine aminotransferase (ALT) levels have been associated with increased risk of diabetes and with increased mortality, but associations of variations of ALT in the normal range with outcomes have been less well studied...
  15. pmc Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events?
    Naveed Sattar
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, Scotland, UK
    PLoS Med 6:e1000099. 2009
    ..We tested whether interleukin (IL)-6, C-reactive protein (CRP), and fibrinogen more strongly associate with fatal compared to nonfatal myocardial infarction (MI) and stroke...
  16. doi request reprint Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
    Muriel J Caslake
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G11 6NT, UK
    Atherosclerosis 210:28-34. 2010
    ..We evaluated the association of Lp-PLA(2) with vascular events in the elderly where the importance of LDL is diminished as a risk factor for coronary disease...
  17. ncbi request reprint C-reactive protein and prediction of coronary heart disease and global vascular events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
    Naveed Sattar
    Department of Vascular Biochemistry, University of Glasgow, Glasgow, Scotland, UK
    Circulation 115:981-9. 2007
    ..The role of C-reactive protein (CRP) in predicting vascular events and response to statin therapy remains uncertain. Additional large prospective studies are required...
  18. pmc Reduced glomerular filtration rate and its association with clinical outcome in older patients at risk of vascular events: secondary analysis
    Ian Ford
    Robertson Centre for Biostatistics, University of Glasgow, Glasgow, Scotland
    PLoS Med 6:e16. 2009
    ..We aimed to determine the predictive value of the GFR for mortality and morbidity using data from the 5,804 participants randomized in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)...
  19. doi request reprint Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials
    Naveed Sattar
    British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Lancet 375:735-42. 2010
    ..We aimed to establish by a meta-analysis of published and unpublished data whether any relation exists between statin use and development of diabetes...
  20. doi request reprint Socioeconomic status and transient ischaemic attack/stroke: a prospective observational study
    Gillian D Kerr
    Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK
    Cerebrovasc Dis 31:130-7. 2011
    ..We aimed to determine whether low-SES stroke/transient ischaemic attack (TIA) patients have a greater burden of vascular risk factors/co-morbidity and reduced health care access...
  21. doi request reprint The incidence and risk factors for new onset atrial fibrillation in the PROSPER study
    Peter W Macfarlane
    Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK
    Europace 13:634-9. 2011
    ..We aimed to determine retrospectively whether pravastatin reduces the incidence of AF and whether any electrocardiographic measures or clinical conditions might be risk factors for its development...
  22. ncbi request reprint Plasma lipoproteins and apolipoproteins as predictors of cardiovascular risk and treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)
    Chris J Packard
    Department of Vascular Biochemistry, University of Glasgow, Glasgow, Scotland
    Circulation 112:3058-65. 2005
    ..We assessed the role of plasma lipoproteins as predictors of risk and of treatment benefit in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)...
  23. ncbi request reprint Can metabolic syndrome usefully predict cardiovascular disease and diabetes? Outcome data from two prospective studies
    Naveed Sattar
    Faculty of Medicine, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
    Lancet 371:1927-35. 2008
    ..We investigated to what extent metabolic syndrome and its individual components were related to risk for these two diseases in elderly populations...
  24. pmc Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach
    Paul Welsh
    Division of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    J Clin Endocrinol Metab 95:93-9. 2010
    ..Associations between adiposity and circulating inflammation markers are assumed to be causal, although the direction of the relationship has not been proven...
  25. ncbi request reprint D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays
    Mark Barber
    University Section of Clinical Gerontology and Vascular Medicine, Royal Infirmary, Glasgow, UK
    Stroke 37:1113-5. 2006
    ..We wished to confirm these findings using commercially available assays and to provide data to allow the design of intervention studies...
  26. ncbi request reprint Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression
    Mark Barber
    University Section of Clinical Gerontology and Vascular Medicine, Royal Infirmary, Glasgow, UK
    Stroke 35:1421-5. 2004
    ..We hypothesized that activation of the coagulation system is an important contributor in some cases of deterioration. We aimed to characterize alterations in circulating hemostatic markers in patients with progressing stroke...
  27. pmc Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
    Dilys J Freeman
    Centre of Population and Health Sciences, University of Glasgow, Glasgow, UK
    BMC Geriatr 11:8. 2011
    ..We aimed to determine the effect of pravastatin on incident VTE in older people; we also studied the impact of clinical and plasma risk variables...
  28. ncbi request reprint Risk factors for chest infection in acute stroke: a prospective cohort study
    Cameron Sellars
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary, Glasgow, UK
    Stroke 38:2284-91. 2007
    ..Pneumonia is a major cause of morbidity and mortality after stroke. We aimed to determine key characteristics that would allow prediction of those patients who are at highest risk for poststroke pneumonia...
  29. pmc Long-term effects of statin treatment in elderly people: extended follow-up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)
    Suzanne M Lloyd
    Robertson Centre for Biostatistics, University of Glasgow, Glasgow, United Kingdom
    PLoS ONE 8:e72642. 2013
    ..However, there was a suggestion of increased cancer risk. Our aim is to determine the long-term benefits and safety of pravastatin treatment in older people using post-trial follow-up of the PROSPER participants...
  30. doi request reprint Do vascular risk factors explain the association between socioeconomic status and stroke incidence: a meta-analysis
    Gillian D Kerr
    Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Cerebrovasc Dis 31:57-63. 2011
    ..Reduced socioeconomic status (SES) is associated with an increased risk of stroke, although the mechanism is not clear. It may be that those with lower SES have a greater burden of classic vascular risk factors...
  31. ncbi request reprint Family caregivers of older relatives: ways of coping and change in distress
    Christina Knussen
    Department of Psychology, Glasgow Caledonian University, Glasgow, Scotland, UK
    Psychol Health Med 13:274-90. 2008
    ..Focusing on caregiving" was not significantly related to distress. The results highlight the potential benefits to these caregivers of maintaining a balance in their lives by taking breaks from caregiving...
  32. doi request reprint Reliability (inter-rater agreement) of the Barthel Index for assessment of stroke survivors: systematic review and meta-analysis
    Laura Duffy
    Department of Academic Geriatric Medicine, Walton Building, Glasgow Royal Infirmary, Glasgow, G4 0SF United Kingdom
    Stroke 44:462-8. 2013
    ..We sought to describe the reliability (interobserver variability) of standard BI in stroke cohorts using systematic review and meta-analysis of published studies...
  33. ncbi request reprint Screening for cognitive impairment in older people attending accident and emergency using the 4-item Abbreviated Mental Test
    Irene Schofield
    Glasgow Caledonian University, Glasgow, UK
    Eur J Emerg Med 17:340-2. 2010
    ..5% (95% CI: 44-57%) sensitivity and 98.6% (95% CI: 0 96-1.00%) specificity. In conclusion, the AMT4 performs as well as the 10-point AMT in screening for cognitive impairment, and will assist in the early detection of cognitive problems...
  34. ncbi request reprint Predictors of early neurological deterioration after ischaemic stroke: a case-control study
    Mark Barber
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary, Glasgow, UK
    Gerontology 50:102-9. 2004
    ..Early neurological deterioration after ischaemic stroke (stroke in progression) is reported to be common and associated with poor outcome or death. The causes of progressing stroke are, however, uncertain...
  35. ncbi request reprint Randomised controlled trial of electrical stimulation of the quadriceps after proximal femoral fracture
    Virginia Braid
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary, Glasgow G31 2ER, UK
    Aging Clin Exp Res 20:62-6. 2008
    ..This study aimed to determine whether training of the quadriceps using electrical stimulation (ES) increases leg extensor power and decreases disability in elderly subjects rehabilitating after fracture...
  36. ncbi request reprint Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial
    James Shepherd
    University Department of Pathological Biochemistry, University of Glasgow, Royal Infirmary, Scotland, Glasgow, UK
    Lancet 360:1623-30. 2002
    ..Our aim was to test the benefits of pravastatin treatment in an elderly cohort of men and women with, or at high risk of developing, cardiovascular disease and stroke...
  37. ncbi request reprint Validity and reliability of estimating the scandinavian stroke scale score from medical records
    Mark Barber
    Academic Section of Geriatric Medicine, Royal Infirmary, Glasgow, UK
    Cerebrovasc Dis 17:224-7. 2004
    ..Obtaining this information prospectively requires significant resources. We wished to assess the reliability of estimating the Scandinavian Stroke Scale (SSS) score retrospectively from routine hospital admission records...
  38. doi request reprint Barthel index for stroke trials: development, properties, and application
    Terence J Quinn
    Department of Academic Geriatric Medicine, Institute of Cardiovascular and Medical Services, University of Glasgow, UK
    Stroke 42:1146-51. 2011
    ..Of the various measures available, the Barthel index (BI) is one of the more prevalent. We aimed to describe validity, reliability, and responsiveness (clinimetric properties) of the BI in stroke trials...
  39. pmc Developing and evaluating the implementation of a complex intervention: using mixed methods to inform the design of a randomised controlled trial of an oral healthcare intervention after stroke
    Marian C Brady
    Nursing, Midwifery and Allied Health Professions Research Unit, Glasgow Caledonian University, Glasgow, UK
    Trials 12:168. 2011
    ..Our aim was to develop and evaluate the implementation of a complex, multidimensional oral health care (OHC) intervention for people in stroke rehabilitation settings which would inform the development of a randomised controlled trial...
  40. ncbi request reprint Validity of the Telephone Interview for Cognitive Status (TICS) in post-stroke subjects
    Mark Barber
    Academic Section of Geriatric Medicine, Royal Infirmary, Glasgow, UK
    Int J Geriatr Psychiatry 19:75-9. 2004
    ..We wished to test the validity of the Telephone Interview for Cognitive Status (TICS) for cognitive testing in post-stroke subjects...
  41. doi request reprint Should oral nutritional supplementation be given to undernourished older people upon hospital discharge? A controlled trial
    Marion E T McMurdo
    Ageing and Health, University of Dundee, Dundee, Scotland, United Kingdom
    J Am Geriatr Soc 57:2239-45. 2009
    ..To determine whether the oral nutritional supplementation of undernourished older people upon discharge from hospital improves muscle function and reduces disability...
  42. doi request reprint Elevated troponin after stroke: a systematic review
    Gillian Kerr
    Academic Section of Geriatric Medicine, Faculty of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Cerebrovasc Dis 28:220-6. 2009
    ..Troponin levels are elevated in some acute stroke patients, but the clinical significance of this is unclear...
  43. ncbi request reprint Feasibility and diagnostic accuracy of early mood screening to diagnose persisting clinical depression/anxiety disorder after stroke
    Rosalind Lees
    Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK
    Cerebrovasc Dis 37:323-9. 2014
    ..However, there is no consensus on timing or method of assessment. We investigated the feasibility and accuracy of a very early screening strategy and the diagnostic accuracy this has for depression/anxiety disorders at 1 month...
  44. ncbi request reprint Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within community dwelling populations
    Terry J Quinn
    Cardiovascular and Medical Sciences, University of Glasgow, Walton Building, Glasgow Royal Infirmary, Glasgow, UK, G4 0SF
    Cochrane Database Syst Rev 4:CD010079. 2014
    ..A synthesis of the available data regarding IQCODE accuracy will help inform cognitive assessment strategies for clinical practice, research and policy...
  45. ncbi request reprint Non-pharmacological interventions for caregivers of stroke survivors
    Lynn A Legg
    Academic Section of Geriatric Medicine, Division of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Room 5, 4th Floor, Walton Building, Royal Infirmary, Glasgow, UK, G4 0SF
    Cochrane Database Syst Rev 10:CD008179. 2011
    ..A range of interventions targeted towards stroke survivors and their family or other informal caregivers have been tested in randomised controlled trials (RCTs). ..
  46. ncbi request reprint How far to investigate older people?
    B J Adler
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary
    Clin Med 3:418-22. 2003
  47. ncbi request reprint Anaemia in elderly patients
    Lesley McCormick
    Academic Section of Geriatric Medicine, Glasgow Royal Infirmary
    Clin Med 7:501-4. 2007
  48. ncbi request reprint Homocysteine, vitamin B-12, and folic acid and the risk of cognitive decline in old age: the Leiden 85-Plus study
    Simon P Mooijaart
    Departments of Gerontology and Geriatrics and Clinical Chemistry, Leiden University Medical Center, Leiden, Netherlands
    Am J Clin Nutr 82:866-71. 2005
    ..High concentrations of homocysteine and low concentrations of vitamin B-12 and folic acid are frequently observed in subjects with dementia...
  49. ncbi request reprint Chronic heart failure and cognitive impairment: co-existence of conditions or true association?
    Jacqueline Taylor
    Eur J Heart Fail 4:7-9. 2002
  50. ncbi request reprint Homocysteine, B vitamins, and cardiovascular disease
    Anton J M de Craen
    N Engl J Med 355:205-6; author reply 209-11. 2006
  51. ncbi request reprint An internationally agreed definition of progressing stroke
    Mark Barber
    Cerebrovasc Dis 18:255-6; author reply 256-7. 2004
  52. ncbi request reprint Predictors of functional decline in elderly people with vascular risk factors or disease
    Adriaan M Kamper
    Department of Gerontology and Geriatrics, C2 R Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlands
    Age Ageing 34:450-5. 2005
    ..to determine contributors to decline in functional capacity in elderly patients with known vascular risk factors or disease...