J Stocks

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Effect of airway inflation pressure on forced expiratory maneuvers from raised lung volume in infants
    Sooky Lum
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital NHS Trust, London, United Kingdom
    Pediatr Pulmonol 33:130-4. 2002
  2. ncbi Lung function and respiratory symptoms at 11 years in children born extremely preterm: the EPICure study
    Joseph Fawke
    Portex Unit Respiratory Physiology and Medicine, UCL, Institute of Child Health, WC1N 1EH London, UK
    Am J Respir Crit Care Med 182:237-45. 2010
  3. ncbi Respiratory function testing in early childhood: where have we come from and where are we going?
    J Stocks
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London
    Pediatr Pulmonol Suppl 18:24-8. 1999
  4. ncbi The effect of parental smoking on lung function and development during infancy
    Janet Stocks
    Portex Anesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    Respirology 8:266-85. 2003
  5. ncbi Introduction and overview of preschool lung function testing
    Janet Stocks
    Portex Unit: Respiratory Physiology, UCL, Institute of Child Health, London, UK
    Paediatr Respir Rev 7:S2-4. 2006
  6. ncbi Clinical implications of pulmonary function testing in preschool children
    Janet Stocks
    Portex Unit Respiratory Physiology, UCL, Institute of Child Health, London, UK
    Paediatr Respir Rev 7:S26-9. 2006
  7. ncbi Lung function in infants and young children with chronic lung disease of infancy: the next steps?
    Janet Stocks
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Pediatr Pulmonol 42:3-9. 2007
  8. ncbi Nature and severity of lung function abnormalities in extremely pre-term children at 11 years of age
    S Lum
    Portex Unit, Respiratory Physiology and Medicine, UCL, Institute of Child Health, London, WC1N 1EH, UK
    Eur Respir J 37:1199-207. 2011
  9. ncbi Association of prematurity, lung disease and body size with lung volume and ventilation inhomogeneity in unsedated neonates: a multicentre study
    G Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    Thorax 64:240-5. 2009
  10. ncbi The relationship between tPTEF:tE and specific airway conductance in infancy
    C A Dezateux
    Unit of Epidemiology and Biostatistics, Institute of Child Health, London, England
    Pediatr Pulmonol 18:299-307. 1994

Collaborators

Detail Information

Publications77

  1. ncbi Effect of airway inflation pressure on forced expiratory maneuvers from raised lung volume in infants
    Sooky Lum
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital NHS Trust, London, United Kingdom
    Pediatr Pulmonol 33:130-4. 2002
    ..5), and FEF(75) by RVRTC technique. Precision in setting and reporting the applied P(inf) is therefore essential, particularly if data are to be compared between centers...
  2. ncbi Lung function and respiratory symptoms at 11 years in children born extremely preterm: the EPICure study
    Joseph Fawke
    Portex Unit Respiratory Physiology and Medicine, UCL, Institute of Child Health, WC1N 1EH London, UK
    Am J Respir Crit Care Med 182:237-45. 2010
    ..The long-term respiratory sequelae of infants born extremely preterm (EP) and now graduating from neonatal intensive care remains uncertain...
  3. ncbi Respiratory function testing in early childhood: where have we come from and where are we going?
    J Stocks
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London
    Pediatr Pulmonol Suppl 18:24-8. 1999
    ....
  4. ncbi The effect of parental smoking on lung function and development during infancy
    Janet Stocks
    Portex Anesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    Respirology 8:266-85. 2003
    ....
  5. ncbi Introduction and overview of preschool lung function testing
    Janet Stocks
    Portex Unit: Respiratory Physiology, UCL, Institute of Child Health, London, UK
    Paediatr Respir Rev 7:S2-4. 2006
  6. ncbi Clinical implications of pulmonary function testing in preschool children
    Janet Stocks
    Portex Unit Respiratory Physiology, UCL, Institute of Child Health, London, UK
    Paediatr Respir Rev 7:S26-9. 2006
    ....
  7. ncbi Lung function in infants and young children with chronic lung disease of infancy: the next steps?
    Janet Stocks
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Pediatr Pulmonol 42:3-9. 2007
    ....
  8. ncbi Nature and severity of lung function abnormalities in extremely pre-term children at 11 years of age
    S Lum
    Portex Unit, Respiratory Physiology and Medicine, UCL, Institute of Child Health, London, WC1N 1EH, UK
    Eur Respir J 37:1199-207. 2011
    ..Spirometry proved an effective means of detecting these persistent abnormalities...
  9. ncbi Association of prematurity, lung disease and body size with lung volume and ventilation inhomogeneity in unsedated neonates: a multicentre study
    G Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    Thorax 64:240-5. 2009
    ..We aimed to establish whether such findings are associated with the degree of prematurity, neonatal respiratory illness and disproportionate somatic growth...
  10. ncbi The relationship between tPTEF:tE and specific airway conductance in infancy
    C A Dezateux
    Unit of Epidemiology and Biostatistics, Institute of Child Health, London, England
    Pediatr Pulmonol 18:299-307. 1994
    ..Further work is needed to elucidate the factors influencing tidal expiratory flow patterns in infancy...
  11. ncbi The association between birthweight, sex, and airway function in infants of nonsmoking mothers
    S Lum
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    Am J Respir Crit Care Med 164:2078-84. 2001
    ..Furthermore, FEF(75) was on average 35 ml s(-1) lower in boys than girls (95% CI: -61, -8). We conclude that diminished airway function in SGA infants shortly after birth appears to be primarily mediated through impaired somatic growth...
  12. ncbi Influence of jacket placement on respiratory compliance during raised lung volume measurements in infants
    A F Hoo
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, 30 Guilford Street, London WC1N 1EH, United Kingdom
    Pediatr Pulmonol 31:51-8. 2001
    ....
  13. ncbi Respiratory compliance in infants--a preliminary evaluation of the multiple interrupter technique
    M E Fletcher
    Respiratory Laboratory, Hospital for Sick Children, London, UK
    Pediatr Pulmonol 14:118-25. 1992
    ..From this preliminary study, the MIT proved as successful as the MOT, requiring fewer occluded breaths to measure Crs. In infants with a rapid respiratory rate, the data from several expirations can be merged and analyzed as for the MOT...
  14. ncbi Reference values for lung function: past, present and future
    S Stanojevic
    Portex Respiratory Physiology Unit, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
    Eur Respir J 36:12-9. 2010
    ..We aim to highlight some of the main issues in selecting and using reference equations and discuss how recent developments may improve interpretation of pulmonary function results...
  15. ncbi Hering-Breuer reflex and respiratory system compliance in the first year of life: a longitudinal study
    P S Rabbette
    Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    J Appl Physiol 76:650-6. 1994
    ..1 +/- 8.9 (SD) to 149.0 +/- 20.6 ml/kPa between 6 wk and 1 yr. However, there was no apparent relationship between the magnitude of decline in HBR response and the age-related changes in Crs.(ABSTRACT TRUNCATED AT 250 WORDS)..
  16. ncbi Lung function from infancy to the preschool years after clinical diagnosis of cystic fibrosis
    Wanda J Kozlowska
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 178:42-9. 2008
    ..After recent standardization of forced expiratory maneuvers for both infants and preschool children, longitudinal measurements are now possible from birth...
  17. ncbi Airway function at one year: association with premorbid airway function, wheezing, and maternal smoking
    C Dezateux
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Thorax 56:680-6. 2001
    ..The aim of this study was to examine the association of diminished premorbid airway function, prior wheezing, and maternal smoking with airway function at 1 year of age...
  18. ncbi Reference equations for specific airway resistance in children: the Asthma UK initiative
    J Kirkby
    Portex Respiratory Unit, University College London, Institute of Child Health, London, UK
    Eur Respir J 36:622-9. 2010
    ..Given the potential clinical usefulness of sR(aw), particularly with respect to sR(eff), methodological guidelines need to be established and used in prospective data collection...
  19. ncbi The EPICure study: maximal exercise and physical activity in school children born extremely preterm
    Liam Welsh
    Portex Unit Respiratory Medicine and Physiology, UCL, Institute of Child Health, London, UK
    Thorax 65:165-72. 2010
    ..Since survivors remain at high risk for developing bronchopulmonary dysplasia (BPD) and long-term pulmonary sequelae, reductions in exercise capacity and activity levels may be present...
  20. ncbi Infant respiratory function after RSV-proven bronchiolitis
    C Dezateux
    Department of Epidemiology and Biostatistics, Institute of Child Health, London, United Kingdom
    Am J Respir Crit Care Med 155:1349-55. 1997
    ..Longitudinal studies are needed to clarify whether subclinical alterations in airway function precede acute bronchiolitis...
  21. ncbi Effect of raised lung volume technique on subsequent measures of V'maxFRC in infants
    S Lum
    Portex Anesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    Pediatr Pulmonol 38:146-54. 2004
    ..Further research is needed to clarify the potential mechanisms. In the meantime, the potential impact of the order of lung function tests within any given study protocol should be considered carefully...
  22. ncbi Lung function tests in neonates and infants with chronic lung disease of infancy: functional residual capacity
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children National Health Service NHS Trust, London, UK
    Pediatr Pulmonol 41:1-22. 2006
    ..Although lung volume measurements in extremely preterm infants were described in a research environment, resolution of several issues is required before such investigations can be translated into routine clinical monitoring...
  23. ncbi The evolution of airway function in early childhood following clinical diagnosis of cystic fibrosis
    Sarath C Ranganathan
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 169:928-33. 2004
    ..5) of 20% (11, 28). Airway function is diminished soon after diagnosis in infants with CF and does not catch up during infancy and early childhood. These findings have important implications for early interventions in CF...
  24. ncbi Relative ability of full and partial forced expiratory maneuvers to identify diminished airway function in infants with cystic fibrosis
    Sarath C Ranganathan
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    Am J Respir Crit Care Med 166:1350-7. 2002
    ..In infants with CF, the raised volume technique identified diminished airway function more frequently than the tidal technique...
  25. ncbi Assessment of passive respiratory mechanics in infants: double versus single occlusion?
    I Goetz
    Portex Anaesthesia, Intensive Therapy and Respiratory Unit, Institute of Child Health, London, UK
    Eur Respir J 17:449-55. 2001
    ..Further work is required to investigate the clinical and epidemiological relevance of this new approach, and whether there are any advantages of using both techniques when assessing passive mechanics in infants...
  26. ncbi Low birth weight for gestation and airway function in infancy: exploring the fetal origins hypothesis
    C Dezateux
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, UK
    Thorax 59:60-6. 2004
    ..We examined the hypothesis that low birth weight for gestation is associated with impaired airway function shortly after birth and that this is independent of impaired postnatal somatic growth...
  27. ncbi Assessment of airway function using partial expiratory flow-volume curves: How reliable are measurements of maximal expiratory flow at frc during early infancy?
    M Henschen
    Portex Anaesthesia, Intensive Therapy, and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital, London, United
    Am J Respir Crit Care Med 159:480-6. 1999
    ..g., 3 ml/kg) above EEV, rather than at the FRC that is operational at the time of measurement...
  28. ncbi Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis
    P Aurora
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Thorax 59:1068-73. 2004
    ....
  29. ncbi The EPICure study: comparison of pediatric spirometry in community and laboratory settings
    J Kirkby
    Portex Anaesthesia, Intensive Therapy, Respiratory Medicine and Respiratory Physiology Unit, UCL, Institute of Child Health, London, UK
    Pediatr Pulmonol 43:1233-41. 2008
    ..We compared spirometry measurements obtained by trained pediatricians in a variety of school settings with those obtained in the laboratory by respiratory physiologists...
  30. ncbi Effect of chest wall vibration timing on peak expiratory flow and inspiratory pressure in a mechanically ventilated lung model
    H Shannon
    Portex Unit Respiratory Physiology and Physiotherapy, UCL Institute of Child Health, London, UK
    Physiotherapy 96:344-9. 2010
    ..To investigate the effects of chest wall vibration timing on air flow and pressure in a ventilated lung model...
  31. ncbi Exploring the relationship between forced maximal flow at functional residual capacity and parameters of forced expiration from raised lung volume in healthy infants
    S C Ranganathan
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Pediatr Pulmonol 33:419-28. 2002
    ..3% and 8.9%, respectively).A more standardized protocol when analyzing data from the RVRTC would facilitate comparisons of results between centers in the future...
  32. ncbi The Young Everest Study: effects of hypoxia at high altitude on cardiorespiratory function and general well-being in healthy children
    E Scrase
    Department of Paediatric Respiratory Medicine, Great Ormond Street Hospital for Children NHS Trust, London WC1N 3JH, UK
    Arch Dis Child 94:621-6. 2009
    ..To assess the effect of altitude and acclimatisation on cardiorespiratory function and well-being in healthy children...
  33. ncbi Lung clearance index at 4 years predicts subsequent lung function in children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, UCL Institute of Child Health, 30 Guilford St, London WC1N 1EH, UK
    Am J Respir Crit Care Med 183:752-8. 2011
    ..There is an urgent need for alternative surrogates that detect early lung disease and track through early childhood...
  34. ncbi The influence of endotracheal tube leak on the assessment of respiratory function in ventilated children
    E Main
    Physiotherapy Department, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1 N 3JH, UK
    Intensive Care Med 27:1788-97. 2001
    ..This study aimed to assess the influence of tracheal tube leak on measurements of C(rs), R(rs) and expired tidal volume (V(TE)) in ventilated children in order to establish when such measurements were reliable in this population...
  35. ncbi Sex-specific prediction equations for Vmax(FRC) in infancy: a multicenter collaborative study
    Ah Fong Hoo
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children National Health Service Trust, London, UK
    Am J Respir Crit Care Med 165:1084-92. 2002
    ..Appropriate use of z scores, which indicate a "normal" range (z scores of 0 +/- 2) for Vmax(FRC), during infancy should also improve interpretation of both clinical and research studies...
  36. ncbi Development of airway function in infancy after preterm delivery
    Ah-Fong Hoo
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health and Great Ormond Street Hospital NHS Trust, London, United Kingdom
    J Pediatr 141:652-8. 2002
    ..64). CONCLUSIONS: Airway function during the first year shows considerable tracking. Even in the absence of neonatal respiratory disease, preterm delivery is associated with altered airway development during early infancy...
  37. ncbi Influence of jacket tightness and pressure on raised lung volume forced expiratory maneuvers in infants
    Sooky Lum
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital NHS Trust, London, United Kingdom
    Pediatr Pulmonol 34:361-8. 2002
    ..In addition, when using a loosened jacket or a higher than "optimal" P(j), chest wall and upper airway reflexes such as glottic closure, peripheral airway closure, and negative flow dependence were more evident...
  38. ncbi Potential misinterpretation of infant lung function unless prospective healthy controls are studied
    Sooky Lum
    Portex Unit, Respiratory Physiology and Medicine, UCL, Institute of Child Health, London, UK
    Pediatr Pulmonol 45:906-13. 2010
    ..SUMMARY RATIONALE: Reliable interpretation of pulmonary function tests relies on appropriate reference data, which remain very limited for infants...
  39. ncbi Long-term impact of neonatal intensive care and surgery on somatosensory perception in children born extremely preterm
    Suellen M Walker
    Portex Unit, Pain Research and Respiratory Physiology, UCL Institute of Child Health, 6th Floor Cardiac Wing, 30 Guilford St, London WC1N 1EH, UK
    Pain 141:79-87. 2009
    ....
  40. ncbi Lung function tests in neonates and infants with chronic lung disease: forced expiratory maneuvers
    Sooky Lum
    Portex Respiratory Unit, Institute Institute of Child Health, London, UK
    Pediatr Pulmonol 41:199-214. 2006
    ....
  41. ncbi Gas mixing efficiency from birth to adulthood measured by multiple-breath washout
    Paul Aurora
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Respir Physiol Neurobiol 148:125-39. 2005
    ..Although methodological and analytical issues remain, the future clinical and research applications of MBW justify accelerated research in this field...
  42. ncbi Early detection of cystic fibrosis lung disease: multiple-breath washout versus raised volume tests
    Sooky Lum
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Thorax 62:341-7. 2007
    ....
  43. ncbi Quality control for spirometry in preschool children with and without lung disease
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 169:1152-9. 2004
    ..We describe recommendations for modified start of test and repeatability criteria for this age group, and for improvements in software to facilitate better quality control...
  44. ncbi Repeatability of physiotherapy chest wall vibrations applied to spontaneously breathing adults
    Harriet Shannon
    University College London, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Physiotherapy 95:36-42. 2009
    ..In order to understand their effects, it is essential to measure the forces applied and their repeatability over time. This study investigated the repeatability of vibrations within and between test occasions...
  45. ncbi Spirometry centile charts for young Caucasian children: the Asthma UK Collaborative Initiative
    Sanja Stanojevic
    Portex Unit, Respiratory Physiology and Medicine, UCL, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 180:547-52. 2009
    ....
  46. ncbi Development of lung function in early life: influence of birth weight in infants of nonsmokers
    Ah Fong Hoo
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 170:527-33. 2004
    ..These findings suggest that lung function is reduced in low birth weight for gestation infants born to nonsmoking white mothers and that this is independent of somatic growth during infancy...
  47. ncbi Reference ranges for spirometry across all ages: a new approach
    Sanja Stanojevic
    Portex Respiratory Physiology Unit, UCL Institute of Child Health, 30 Guilford Street, London, WC1N 1EH UK
    Am J Respir Crit Care Med 177:253-60. 2008
    ....
  48. ncbi Reference equations for pulmonary function tests in preschool children: a review
    Sanja Stanojevic
    Portex Respiratory Physiology Unit, UCL, Institute of Child Health, London, United Kingdom
    Pediatr Pulmonol 42:962-72. 2007
    ..This in turn would maximize the tremendous opportunities to detect early lung disease offered by the recent surge in developing suitable tests for preschool children...
  49. ncbi Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 171:249-56. 2005
    ..Most preschool children can perform multiple-breath washout, plethysmography, and spirometry at first attempt. Multiple-breath washout detects abnormal lung function in children with CF more readily than plethysmography or spirometry...
  50. ncbi Progressive decline in plethysmographic lung volumes in infants: physiology or technology?
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    Am J Respir Crit Care Med 168:1003-9. 2003
    ..These findings emphasize the need to establish reference data for lung function tests in infants that are appropriate for the equipment and protocols in current use...
  51. ncbi Influence of volume dependency and timing of airway occlusions on the Hering-Breuer reflex in infants
    P S Rabbette
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, and Great Ormond Street Hospital, National Health Service Trust, London WC1N 1EH, United Kingdom
    J Appl Physiol 85:2033-9. 1998
    ..Age-related changes in the volume threshold may reflect maturational changes in the control of breathing and respiratory mechanics throughout the first year of life...
  52. ncbi Plethysmographic measurements of lung volume and airway resistance. ERS/ATS Task Force on Standards for Infant Respiratory Function Testing. European Respiratory Society/ American Thoracic Society
    J Stocks
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Eur Respir J 17:302-12. 2001
    ..These guidelines cover numerous aspects including terminology and definitions, equipment, data acquisition and analysis and reporting of results and also highlight areas where further research is needed before consensus can be reached...
  53. ncbi Airway function in infants treated with inhaled nitric oxide for persistent pulmonary hypertension
    Aparna U Hoskote
    Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Pediatr Pulmonol 43:224-35. 2008
    ....
  54. ncbi Limitations of electronic compensation for measuring plethysmographic airway resistance in infants
    Padmaja Subbarao
    Portex Respiratory Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    Pediatr Pulmonol 40:45-52. 2005
    ..The marked within- and between-subject variability in healthy infants, and lack of discriminative power of R(aw) when derived from electronically compensated values, currently preclude application in either clinical or research studies...
  55. ncbi Interpretation of pediatric lung function: impact of ethnicity
    J Kirkby
    Portex Unit, Respiratory Physiology and Medicine, UCL Institute of Child Health, London, UK
    Pediatr Pulmonol 48:20-6. 2013
    ..To evaluate the appropriateness of spirometric and plethysmographic reference equations in healthy young children according to ethnic origin...
  56. ncbi Alveolar LCI vs. standard LCI in detecting early CF lung disease
    K Haidopoulou
    Fourth Department of Paediatrics, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
    Respir Physiol Neurobiol 180:247-51. 2012
    ..LCI) was not significant (p=0.36). We conclude that LCI is minimally affected by airway deadspace, or relative equipment deadspace, and is an appropriate measure of lung function in infancy...
  57. ncbi Lung function testing in infants
    J Stocks
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Pediatr Pulmonol Suppl 18:14-20. 1999
    ..They also have the potential to provide valuable objective outcome measures in the quest for effective preventive and therapeutic strategies in respiratory medicine...
  58. ncbi Respiratory function during infancy in survivors of the INNOVO trial
    Ah Fong Hoo
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health, London, UK
    Pediatr Pulmonol 44:155-61. 2009
    ..Furthermore, results were compared to lung function of healthy infants...
  59. ncbi Functional residual capacity measurements in healthy infants: ultrasonic flow meter versus a mass spectrometer
    J J Pillow
    Portex Unit Respiratory Physiology, Institute of Child Health, University College London Hospital NHS Trust, London, UK
    Eur Respir J 23:763-8. 2004
    ..7%) and FRCUS (5.2%). The ultrasonic flow meter used in this study provides repeatable measurements of functional residual capacity in spontaneously breathing healthy infants that approximate those obtained during mass spectrometry...
  60. ncbi Accuracy of displayed values of tidal volume in the pediatric intensive care unit
    Rosemary A Castle
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Crit Care Med 30:2566-74. 2002
    ..CONCLUSIONS: The accuracy of tidal volume values is crucially dependent on the site of measurement. Unless measured at the airway opening, displayed values are an inconsistent and misleading indicator of the true volumes delivered...
  61. ncbi The influence of physiotherapy and suction on respiratory deadspace in ventilated children
    Eleanor Main
    Centre for Nursing and Allied Health Professionals Research and Physiotherapy Department, Institute of Child Health, 7th Floor, Old Building, Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WCIN 3JH, UK
    Intensive Care Med 30:1152-9. 2004
    ....
  62. ncbi Lung function testing in acute neonatal respiratory disorders and chronic lung disease of infancy: a review series
    Georg Hulskamp
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children National Health Service NHS Trust, London, UK
    Pediatr Pulmonol 40:467-70. 2005
  63. ncbi Effect of delayed sternal closure after cardiac surgery on respiratory function in ventilated infants
    E Main
    Physiotherapy Department, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Crit Care Med 29:1798-802. 2001
    ..Accurate assessment of change in respiratory system compliance after any therapeutic intervention may be precluded by changes in tracheal tube leak during the procedure...
  64. ncbi Neonatal ventilation with inhaled nitric oxide vs. ventilatory support without inhaled nitric oxide for infants with severe respiratory failure born at or near term: the INNOVO multicentre randomised controlled trial
    D Field
    Department of Health Science, University of Leicester, London, UK
    Neonatology 91:73-82. 2007
    ..Evidence from European centres to support the use of nitric oxide (NO) in mature newborns with evidence of severe respiratory failure is sparse...
  65. ncbi A comparison of the respiratory effects of sevoflurane and halothane in infants and young children
    K Brown
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, United Kingdom
    Anesthesiology 89:86-92. 1998
    ..This study compared the respiratory effects of sevoflurane with those of halothane in anesthetized infants and young children...
  66. ncbi Assessment of tidal breathing parameters in infants with cystic fibrosis
    S C Ranganathan
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Eur Respir J 22:761-6. 2003
    ..An elevated respiratory rate may be due in part to ventilation heterogeneity but is poorly predictive of diminished airway function measured by forced expiration...
  67. ncbi Respiratory physiotherapy vs. suction: the effects on respiratory function in ventilated infants and children
    Eleanor Main
    Centre for Nursing and Allied Health Professionals Research, Institute of Child Health, London and Physiotherapy Department, Great Ormond Street Hospital for Children NHS Trust, London WCIN 3JH, UK
    Intensive Care Med 30:1144-51. 2004
    ..To assess and compare the effects of physiotherapy and suction on expired tidal volume (V(TE)), respiratory compliance (C(rs)), resistance (R(rs)) and arterial blood gases...
  68. ncbi Reproducibility and reversibility of tidal forced expirations
    Sooky Lum
    Respiration 70:556; reply 556-7. 2003
  69. ncbi Lung-function tests in neonates and infants with chronic lung disease: tidal breathing and respiratory control
    David N Baldwin
    Centre for Child Health Research and Telethon Institute for Child Health Research, University of Western Australia, Perth, Western Australia, Australia
    Pediatr Pulmonol 41:391-419. 2006
    ..Clinical observations are supported by formal comparison of tidal breathing parameters and control of breathing indices in the research setting...
  70. ncbi An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children
    Nicole Beydon
    Am J Respir Crit Care Med 175:1304-45. 2007
  71. ncbi Appropriate interpretation of lung function and exercise capacity in a longitudinal follow-up of preterm children
    Jane Kirkby
    Am J Respir Crit Care Med 175:96-7; author reply 97. 2007
  72. ncbi Multiple breath washout with a sidestream ultrasonic flow sensor and mass spectrometry: a comparative study
    Susanne I Fuchs
    Department of Paediatric Pulmonology and Neonatology, Medizinische Hochschule, Hannover, Germany
    Pediatr Pulmonol 41:1218-25. 2006
    ..This prototype system could be the basis for a commercial device allowing more widespread application of MBW in the near future...
  73. ncbi Lung function tests in neonates and infants with chronic lung disease: lung and chest-wall mechanics
    Monika Gappa
    Department of Pediatric Pulmonology and Neonatology, Medizinische Hochschule Hannover, Hannover, Germany
    Pediatr Pulmonol 41:291-317. 2006
    ..New methods such as the low-frequency forced oscillation technique, which differentiate the tissue and airway components of respiratory mechanics, are likely to require further development before they can be of clinical significance...
  74. ncbi Lung growth and development after preterm birth: further evidence
    Monika Gappa
    Am J Respir Crit Care Med 168:399; author reply 400. 2003
  75. ncbi Partitioning of airway and parenchymal mechanics in unsedated newborn infants
    J Jane Pillow
    Portex Unit, Respiratory Physiology, Institue of Child Health, and Neonatal Unit, University College London Hospital, UK
    Pediatr Res 58:1210-5. 2005
    ..Measurements of lung function are feasible in the unsedated newborn infant using low-frequency forced oscillations and confirm the important contribution of tissue resistance to lung mechanics in the developing lung...
  76. ncbi Lung function tests in neonates and infants with chronic lung disease: global and regional ventilation inhomogeneity
    J Jane Pillow
    Telethon Institute for Child Health Research, University of Western Australia, Perth, Western Australia, Australia
    Pediatr Pulmonol 41:105-21. 2006
    ..For both techniques, there is an urgent need to establish guidelines regarding data collection, analysis, and interpretation in infants both with and without CLDI...
  77. ncbi Infant respiratory function testing: is it worth all the effort?
    Janet Stocks
    Paediatr Anaesth 14:537-40. 2004