Research Topics
Genomes and GenesSpecies | Andrew StockmanSummaryAffiliation: University College London Country: UK Publications
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Publications
Spectrally opponent inputs to the human luminance pathway: slow +L and -M cone inputs revealed by low to moderate long-wavelength adaptationAndrew Stockman
Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
J Physiol 566:77-91. 2005..Although its output generates an achromatic percept, the luminance channel has slow spectrally opponent as well as fast non-opponent inputs...
The loss of the PDE6 deactivating enzyme, RGS9, results in precocious light adaptation at low light levelsAndrew Stockman
Institute of Ophthalmology, University College London, London, UK
J Vis 8:10.1-10. 2008..As the light level is increased and the PDE6* concentration in the normal rises relative to that in the observer lacking RGS9-1, the temporal advantage of the latter is soon lost, leaving only the deficit due to delayed deactivation...
The effect of sildenafil citrate (Viagra) on visual sensitivityAndrew Stockman
Institute of Ophthalmology, University College London, London, UK
J Vis 7:4. 2007..Even for the more affected observers, however, Viagra is unlikely to impair common visual tasks, except under conditions of reduced visibility when objects are already near visual threshold...- Residual cone vision without alpha-transducinAndrew Stockman
Institute of Ophthalmology, University College London, London, UK
J Vis 7:8. 2007.... - Human short-wavelength-sensitive cone light adaptationAndrew Stockman
Institute of Ophthalmology, University College London, London, UK
J Vis 7:4. 2007..Together, these mechanisms act to maintain vision in an optimal operating range and to protect it from overload... - Human cone light adaptation: from behavioral measurements to molecular mechanismsAndrew Stockman
Institute of Ophthalmology, University College London, London, UK
J Vis 6:1194-213. 2006..Together, these mechanisms act to maintain the cone visual system in an optimal operating range and to protect it from overload... - Paradoxical shifts in human color sensitivity caused by constructive and destructive interference between signals from the same cone classAndrew Stockman
Institute of Ophthalmology, University College London, London, United Kingdom
Vis Neurosci 23:471-8. 2006..The shift in spectral sensitivity towards longer wavelengths is accentuated at higher temporal frequencies by a suppression of fast M-cone signals by deep-red fields... - Spectrally opponent inputs to the human luminance pathway: slow +M and -L cone inputs revealed by intense long-wavelength adaptationAndrew Stockman
Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
J Physiol 566:61-76. 2005.... - Into the twilight zone: the complexities of mesopic vision and luminous efficiencyAndrew Stockman
Institute of Ophthalmology, University College London, London EC1V 9EL, UK
Ophthalmic Physiol Opt 26:225-39. 2006..All these should be considered when attempting to derive (or to apply) a luminous efficiency function for mesopic vision... - Long-wavelength adaptation reveals slow, spectrally opponent inputs to the human luminance pathwayAndrew Stockman
Institute of Ophthalmology, University College London, London, UK
J Vis 5:702-16. 2005..Although its output generates an achromatic percept, the luminance channel has spectrally opponent inputs... - Human scotopic sensitivity is regulated postreceptorally by changing the speed of the scotopic responseAndrew Stockman
Institute of Ophthalmology, University College London, London, UK
J Vis 10:12.1-19. 2010..Thus, the scotopic and the photopic systems both regulate their steady-state sensitivity using the same strategy, even though the scotopic system does it largely postreceptorally and the photopic system largely receptorally... - The S-cone contribution to luminance depends on the M- and L-cone adaptation levels: silent surrounds?Caterina Ripamonti
Institute of Ophthalmology, University College London, London, UK
J Vis 9:10.1-16. 2009..We hypothesize that the L + M cone signals produced by the steady adapting backgrounds somehow "gate" the S-cone luminance signals, perhaps by being modulated by them... - The dependence of luminous efficiency on chromatic adaptationAndrew Stockman
Institute of Ophthalmology, University College London, London, UK
J Vis 8:1.1-26. 2008..On backgrounds shorter than 535 nm and longer than 603 nm, the M-cone contribution to luminous efficiency falls short of the proportionality prediction but most likely for different reasons in the two spectral regions... - X-linked cone dystrophy caused by mutation of the red and green cone opsinsJessica C Gardner
UCL Institute of Ophthalmology, 11 43 Bath Street, London EC1V 9EL, UK
Am J Hum Genet 87:26-39. 2010..Mutations in the LW/MW cone opsin gene array can, therefore, lead to a spectrum of disease, ranging from color blindness to progressive cone dystrophy (XLCOD5)... - Early onset retinal dystrophy due to mutations in LRAT: molecular analysis and detailed phenotypic studyArundhati Dev Borman
UCL Institute of Ophthalmology, London, United Kingdom
Invest Ophthalmol Vis Sci 53:3927-38. 2012..To report novel variants and characterize the phenotype associated with the autosomal recessive retinal dystrophy caused by mutations in the lecithin retinol acyltransferase (LRAT) gene... - Effect of gene therapy on visual function in Leber's congenital amaurosisJames W B Bainbridge
Institute of Ophthalmology, University College London, London, United Kingdom
N Engl J Med 358:2231-9. 2008..These findings provide support for further clinical studies of this experimental approach in other patients with mutant RPE65. (ClinicalTrials.gov number, NCT00643747 [ClinicalTrials.gov].)... - A luminous efficiency function, V*(lambda), for daylight adaptationLindsay T Sharpe
Institute of Ophthalmology, University College London, London, United Kingdom
J Vis 5:948-68. 2005..It is extrapolated to wavelengths shorter than 425 nm and longer than 675 nm using the Stockman & Sharpe cone fundamentals... - Identification of novel RPGR ORF15 mutations in X-linked progressive cone-rod dystrophy (XLCORD) familiesNeil D Ebenezer
Division of Molecular Genetics, University College London, UK
Invest Ophthalmol Vis Sci 46:1891-8. 2005.... - Viagra slows the visual response to flickerAndrew Stockman
Curr Biol 16:R44-5. 2006 - Transitions between color categories mapped with a reverse Stroop taskHannah E Smithson
Department of Psychology, Durham University, United Kingdom
Vis Neurosci 23:453-60. 2006..Moreover, it will allow us to quantify the mapping between the chromaticity space defined at the cone photoreceptors and a cognitive color space defined at an advanced level of neural processing...