J P Stewart

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Lung epithelial cells are a major site of murine gammaherpesvirus persistence
    J P Stewart
    Department of Veterinary Pathology, The University of Edinburgh, Edinburgh EH9 1QH, United Kingdom
    J Exp Med 187:1941-51. 1998
  2. ncbi request reprint Murine gamma-herpesvirus 68 glycoprotein 150 protects against virus-induced mononucleosis: a model system for gamma-herpesvirus vaccination
    J P Stewart
    Department of Veterinary Pathology, University of Edinburgh, UK
    Vaccine 17:152-7. 1999
  3. ncbi request reprint Kinetic and phenotypic changes in murine lymphocytes infected with murine gammaherpesvirus-68 in vitro
    B M Dutia
    Department of Veterinary Pathology, University of Edinburgh, Summerhall, UK
    J Gen Virol 80:2729-36. 1999
  4. pmc Natural history of murine gamma-herpesvirus infection
    A A Nash
    Laboratory for Clinical and Molecular Virology, Department of Veterinary Pathology, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK
    Philos Trans R Soc Lond B Biol Sci 356:569-79. 2001
  5. pmc Characterization of tumor cell lines derived from murine gammaherpesvirus-68-infected mice
    E J Usherwood
    Department of Veterinary Pathology, University of Edinburgh, Summerhall, United Kingdom
    J Virol 70:6516-8. 1996
  6. pmc Analysis of a novel strain of murine gammaherpesvirus reveals a genomic locus important for acute pathogenesis
    A I Macrae
    Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Edinburgh EH9 1QH, United Kingdom
    J Virol 75:5315-27. 2001
  7. pmc Role of tachykinins in the host response to murine gammaherpesvirus infection
    C M Payne
    Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Edinburgh EH9 1QH, United Kingdom
    J Virol 75:10467-71. 2001
  8. ncbi request reprint Characterization of the murine gammaherpesvirus 68 ORF74 product: a novel oncogenic G protein-coupled receptor
    M N Wakeling
    Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK
    J Gen Virol 82:1187-97. 2001

Collaborators

Detail Information

Publications8

  1. pmc Lung epithelial cells are a major site of murine gammaherpesvirus persistence
    J P Stewart
    Department of Veterinary Pathology, The University of Edinburgh, Edinburgh EH9 1QH, United Kingdom
    J Exp Med 187:1941-51. 1998
    ..These results show that mucosal epithelia can act as a nonlymphoid reservoir for gammaherpesvirus persistence, and that there is a two-way movement of virus between lymphoid and nonlymphoid compartments during persistence...
  2. ncbi request reprint Murine gamma-herpesvirus 68 glycoprotein 150 protects against virus-induced mononucleosis: a model system for gamma-herpesvirus vaccination
    J P Stewart
    Department of Veterinary Pathology, University of Edinburgh, UK
    Vaccine 17:152-7. 1999
    ..However, mice did establish MHV-68 latency. The results suggest that gp350 may be effective as an immunogen to prevent EBV-associated infectious mononucleosis in humans that are EBV-seronegative...
  3. ncbi request reprint Kinetic and phenotypic changes in murine lymphocytes infected with murine gammaherpesvirus-68 in vitro
    B M Dutia
    Department of Veterinary Pathology, University of Edinburgh, Summerhall, UK
    J Gen Virol 80:2729-36. 1999
    ..This DNA was nuclease sensitive, indicating that, while MHV-68 was efficiently uncoated, its circularization in vitro was extremely inefficient. These results are discussed in terms of the host-virus interaction...
  4. pmc Natural history of murine gamma-herpesvirus infection
    A A Nash
    Laboratory for Clinical and Molecular Virology, Department of Veterinary Pathology, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK
    Philos Trans R Soc Lond B Biol Sci 356:569-79. 2001
    ..Clearly, devising strategies to interrupt the establishment of latent virus infections may well prove impossible with existing methods...
  5. pmc Characterization of tumor cell lines derived from murine gammaherpesvirus-68-infected mice
    E J Usherwood
    Department of Veterinary Pathology, University of Edinburgh, Summerhall, United Kingdom
    J Virol 70:6516-8. 1996
    ..The line was clonable and grew into tumors in nude mice. This is the first naturally occurring MHV-68-positive B-cell line to be generated, and it will be an invaluable tool for the study of MHV-68 latency...
  6. pmc Analysis of a novel strain of murine gammaherpesvirus reveals a genomic locus important for acute pathogenesis
    A I Macrae
    Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Edinburgh EH9 1QH, United Kingdom
    J Virol 75:5315-27. 2001
    ..These results demonstrate that genetic elements at the left end of the unique region of the MHV-68 genome play vital roles in host evasion and are critical to the development of splenic pathology...
  7. pmc Role of tachykinins in the host response to murine gammaherpesvirus infection
    C M Payne
    Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Edinburgh EH9 1QH, United Kingdom
    J Virol 75:10467-71. 2001
    ..Clearance of latently infected cells from the spleen was also delayed. This is the first report of the direct influence of tachykinins in the host response to a virus infection...
  8. ncbi request reprint Characterization of the murine gammaherpesvirus 68 ORF74 product: a novel oncogenic G protein-coupled receptor
    M N Wakeling
    Laboratory for Clinical and Molecular Virology, The University of Edinburgh, Summerhall, Edinburgh EH9 1QH, UK
    J Gen Virol 82:1187-97. 2001
    ..We surmise, therefore, that the MHV GPCR may act in concert with genes with which it is expressed such as vBcl-2 to enhance the growth and survival of MHV-68-infected cells...