P G Stevenson

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi Immune control of mammalian gamma-herpesviruses: lessons from murid herpesvirus-4
    P G Stevenson
    Division of Virology, Department of Pathology, University of Cambridge, UK
    J Gen Virol 90:2317-30. 2009
  2. ncbi Vaccination against a hit-and-run viral cancer
    Philip G Stevenson
    Department of Pathology, University of Cambridge, UK
    J Gen Virol 91:2176-85. 2010
  3. ncbi A secreted chemokine binding protein encoded by murine gammaherpesvirus-68 is necessary for the establishment of a normal latent load
    A Bridgeman
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Exp Med 194:301-12. 2001
  4. ncbi K3-mediated evasion of CD8(+) T cells aids amplification of a latent gamma-herpesvirus
    P G Stevenson
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Nat Immunol 3:733-40. 2002
  5. ncbi Uncoupling of virus-induced inflammation and anti-viral immunity in the brain parenchyma
    P G Stevenson
    Nuffield Department of Medicine, John Radcliffe Hospital, Oxford, UK
    J Gen Virol 83:1735-43. 2002
  6. ncbi MHC class I ubiquitination by a viral PHD/LAP finger protein
    J M Boname
    Department of Pathology, Division of Virology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    Immunity 15:627-36. 2001
  7. ncbi Inhibition of MHC class I-restricted antigen presentation by gamma 2-herpesviruses
    P G Stevenson
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    Proc Natl Acad Sci U S A 97:8455-60. 2000

Collaborators

Detail Information

Publications7

  1. ncbi Immune control of mammalian gamma-herpesviruses: lessons from murid herpesvirus-4
    P G Stevenson
    Division of Virology, Department of Pathology, University of Cambridge, UK
    J Gen Virol 90:2317-30. 2009
    ..Reducing the infectivity of herpesvirus carriers in this way could be a useful adjunct to vaccinating naive individuals with attenuated mutants...
  2. ncbi Vaccination against a hit-and-run viral cancer
    Philip G Stevenson
    Department of Pathology, University of Cambridge, UK
    J Gen Virol 91:2176-85. 2010
    ..Equivalent human gammaherpesvirus vaccines could therefore potentially prevent not only viral genome-positive cancers, but possibly also some cancers less suspected of a viral origin because of viral genome loss...
  3. ncbi A secreted chemokine binding protein encoded by murine gammaherpesvirus-68 is necessary for the establishment of a normal latent load
    A Bridgeman
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    J Exp Med 194:301-12. 2001
    ..In the absence of M3, MHV-68 was unable to establish a normal latent load...
  4. ncbi K3-mediated evasion of CD8(+) T cells aids amplification of a latent gamma-herpesvirus
    P G Stevenson
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Nat Immunol 3:733-40. 2002
    ..CTL depletion reversed the viral latency deficit. Thus, a major function of K3 appears to be CTL evasion during viral latency expansion...
  5. ncbi Uncoupling of virus-induced inflammation and anti-viral immunity in the brain parenchyma
    P G Stevenson
    Nuffield Department of Medicine, John Radcliffe Hospital, Oxford, UK
    J Gen Virol 83:1735-43. 2002
    ..Thus, inflammation and dendritic cell function were both uncoupled from immune priming in the microenvironment of the brain parenchyma and neither was sufficient to overcome immunological privilege...
  6. ncbi MHC class I ubiquitination by a viral PHD/LAP finger protein
    J M Boname
    Department of Pathology, Division of Virology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    Immunity 15:627-36. 2001
    ..Thus, gamma-herpesviruses have adapted the cellular PHD/LAP motif to immune evasion, apparently for the catalysis of MHC class I ubiquitination...
  7. ncbi Inhibition of MHC class I-restricted antigen presentation by gamma 2-herpesviruses
    P G Stevenson
    Division of Virology, Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, United Kingdom
    Proc Natl Acad Sci U S A 97:8455-60. 2000
    ..Thus it appears that an immune evasion strategy shared by at least two gamma-herpesviruses allows continued lytic infection in the face of strong CTL immunity...