Research Topics
Species | A SteptoeSummaryAffiliation: University College London Country: UK Publications
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Publications
Stress and cardiovascular diseaseAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Nat Rev Cardiol 9:360-70. 2012....
Distinctive biological correlates of positive psychological well-being in older men and womenAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London, United Kingdom
Psychosom Med 74:501-8. 2012..We evaluated relationships between both affective and eudaemonic well-being and biological measures in a large sample of older people...
Positive affect and distressed affect over the day in older peopleAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Psychol Aging 26:956-65. 2011..The associations with loneliness highlight the everyday distress and reduced happiness and excitement experienced by lonely older men and women, and these may contribute to enhanced risks to physical and mental health...
Mood and transient cardiac dysfunction in everyday lifeMimi R Bhattacharyya
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Behav Med 34:74-81. 2011..007). There were not changes in high frequency heart rate variability. This small study indicates that emotional state may contribute to vulnerability of cardiac dysfunction in everyday life...
Loneliness and neuroendocrine, cardiovascular, and inflammatory stress responses in middle-aged men and womenAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Psychoneuroendocrinology 29:593-611. 2004..046). We conclude that loneliness is a psychological experience with potentially adverse effects on biological stress processes that may be relevant to health...
Pathogen burden and cortisol profiles over the dayA Steptoe
Department of Epidemiology and Pubic Health, University College London, UK
Epidemiol Infect 137:1816-24. 2009..We conclude that pathogen burden is independently associated with flatter cortisol slopes over the day, and may contribute to disturbed neuroendocrine regulation...
The influence of low job control on ambulatory blood pressure and perceived stress over the working day in men and women from the Whitehall II cohortAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Hypertens 22:915-20. 2004..This study tested the influence of job control on ambulatory blood pressure, and ratings of perceived stress and happiness in men and women systematically sampled by socio-economic status from the Whitehall II epidemiological cohort...
Effort-reward imbalance, overcommitment, and measures of cortisol and blood pressure over the working dayAndrew Steptoe
Department of Epidemiology and Public Health, University College London, UK
Psychosom Med 66:323-9. 2004..To assess the biological correlates of effort-reward imbalance and overcommitment to work using measurements over the working day...
Acute depressed mood as a trigger of acute coronary syndromesAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London, UK
Biol Psychiatry 60:837-42. 2006..Some cases of acute coronary syndrome (ACS) may be triggered by emotional states such as anger, but it is not known if acute depressed mood can act as a trigger...
Psychosocial, hemostatic, and inflammatory correlates of delayed poststress blood pressure recoveryAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London, UK
Psychosom Med 68:531-7. 2006..This study assessed relationships between systolic blood pressure (BP) recovery, psychosocial risk factors, and delayed recovery of inflammatory and hemostatic variables...
Delayed blood pressure recovery after psychological stress is associated with carotid intima-media thickness: Whitehall psychobiology studyAndrew Steptoe
Department of Epidemiology and Public Health, Institute of Child Health, University College London, London WC1E 6BT, UK
Arterioscler Thromb Vasc Biol 26:2547-51. 2006..We tested whether poststress BP recovery was related to carotid atherosclerosis...
Sleep duration and health in young adultsAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, London, England
Arch Intern Med 166:1689-92. 2006..Both long and short sleep durations have been associated with negative health outcomes in middle-aged and older adults. This study assessed the relationship between sleep duration and self-rated health in young adults...
Parental adiposity and cortisol awakening responses in young men and womenAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Psychoneuroendocrinology 31:1117-26. 2006..The results of this study suggest that disturbances of cortisol secretion may present before the emergence of heightened adiposity in young men at raised risk for obesity...
Burden of psychosocial adversity and vulnerability in middle age: associations with biobehavioral risk factors and quality of lifeAndrew Steptoe
Department of Epidemiology and Public Health, University College London, UK
Psychosom Med 65:1029-37. 2003....
The effects of chronic tea intake on platelet activation and inflammation: a double-blind placebo controlled trialAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Atherosclerosis 193:277-82. 2007..We studied the effects of 6 weeks of black tea or placebo on platelet activation, C-reactive protein (CRP), total antioxidant status, and soluble (s) P-Selectin in a randomized double-blind trial...
Positive affect and psychobiological processes relevant to healthAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Pers 77:1747-76. 2009..Positive affect may be part of a broader profile of psychosocial resilience that reduces risk of adverse physical health outcomes...
The effects of tea on psychophysiological stress responsivity and post-stress recovery: a randomised double-blind trialAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, UK
Psychopharmacology (Berl) 190:81-9. 2007..Tea has anecdotally been associated with stress relief, but this has seldom been tested scientifically...
Dispositional optimism and health behaviour in community-dwelling older people: associations with healthy ageingAndrew Steptoe
Department of Epidemiology and Public Health, University College London, UK
Br J Health Psychol 11:71-84. 2006..We assessed whether optimism was related to indices of healthy ageing, and if effects were mediated through health behaviours...
Central adiposity and cortisol responses to waking in middle-aged men and womenA Steptoe
Department of Epidemiology and Public Health, University College London, London, UK
Int J Obes Relat Metab Disord 28:1168-73. 2004..We investigated whether central adiposity indexed by waist/hip ratio is related to cortisol responses to waking and other measures of salivary cortisol over the working day...
Emotional triggering of cardiac eventsAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Neurosci Biobehav Rev 33:63-70. 2009..These factors in turn promote coronary plaque disruption, myocardial ischaemia, cardiac dysrhythmia and thrombus formation. The implications of these findings for patient care and ACS prevention are outlined...
Impact of job and marital strain on ambulatory blood pressureAndrew Steptoe
University College London, London, United Kingdom
Am J Hypertens 18:1138. 2005
Heritability of daytime cortisol levels and cortisol reactivity in childrenAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, UK
Psychoneuroendocrinology 34:273-80. 2009..These findings indicate that individual differences in children's cortisol levels recorded before tasks and cortisol reactivity to behavioural challenges are influenced by genetic factors...
Cardiovascular stress responsivity, body mass and abdominal adiposityA Steptoe
Department of Epidemiology and Public Health, University College London, UK
Int J Obes (Lond) 29:1329-37. 2005....
Positive affect and health-related neuroendocrine, cardiovascular, and inflammatory processesAndrew Steptoe
International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom
Proc Natl Acad Sci U S A 102:6508-12. 2005..These effects were independent of psychological distress, supporting the notion that positive well-being is directly related to health-relevant biological processes...
Positive affect and biological function in everyday lifeAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Neurobiol Aging 26:108-12. 2005....
Socioeconomic position and cardiovascular and neuroendocrine responses following cognitive challenge in old ageAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Biol Psychol 69:149-66. 2005..The results are consistent with the notion that higher SES protects against age-related changes in cardiovascular response profiles, particularly during recovery...
Changes in financial strain over three years, ambulatory blood pressure, and cortisol responses to awakeningAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom
Psychosom Med 67:281-7. 2005..We assessed the influence of changes in financial strain on ambulatory blood pressure and salivary cortisol...
Associations between acute lipid stress responses and fasting lipid levels 3 years laterAndrew Steptoe
Department of Epidemiology and Public Health, University College London, UK
Health Psychol 24:601-7. 2005..Acute lipid stress responsivity may reflect processes that contribute to the development of elevated blood cholesterol concentration...
Smoking, cortisol and nicotineAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Int J Psychophysiol 59:228-35. 2006..The contribution of these findings to understanding the role of neuroendocrine function in smoking is described...
Impaired cardiovascular recovery following stress predicts 3-year increases in blood pressureAndrew Steptoe
International Centre for Health and Society, Psychology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
J Hypertens 23:529-36. 2005..To assess whether variation in the rate of cardiovascular recovery following exposure to acute psychological stress predicts changes in blood pressure longitudinally, independently of blood pressure at baseline and other covariates...
John Moore: eighteenth century physician, bearleader and social observerAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK
J R Soc Med 98:70-4. 2005
Psychological and social predictors of changes in fruit and vegetable consumption over 12 months following behavioral and nutrition education counselingAndrew Steptoe
University College London, Department of Epidemiology and Public Health, London, England
Health Psychol 23:574-81. 2004..These factors accounted for 51% of the superiority of behavioral counseling over nutrition education...
Health behaviour patterns in relation to hypertension: the English Longitudinal Study of AgeingAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, UK
J Hypertens 27:224-30. 2009..We assessed health behaviours in a large sample of older hypertensive individuals, and tested whether medication for hypertension leads to compensatory increases in cardiovascular risk behaviours...
Socioeconomic status and hemodynamic recovery from mental stressAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, London, UK
Psychophysiology 40:184-91. 2003..Results are consistent with the hypothesis that disturbances of stress-related autonomic processes are relevant to the social gradient in cardiovascular disease risk...
Socioeconomic status and subclinical coronary disease in the Whitehall II epidemiological studyAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London, United Kingdom
PLoS ONE 5:e8874. 2010....
Neuroendocrine and cardiovascular correlates of positive affect measured by ecological momentary assessment and by questionnaireAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Psychoneuroendocrinology 32:56-64. 2007..Effects were substantially stronger when positive affect was assessed by aggregating EMA samples than with questionnaire measures...
Neuroendocrine and inflammatory factors associated with positive affect in healthy men and women: the Whitehall II studyAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London, United Kingdom
Am J Epidemiol 167:96-102. 2008..These results confirm findings from smaller studies relating cortisol with positive affect while suggesting that in women, positive affect is associated with reduced levels of inflammatory markers...
Depressive symptoms, socio-economic background, sense of control, and cultural factors in university students from 23 countriesAndrew Steptoe
Department of Epidemiology and Public Health, University College London, UK
Int J Behav Med 14:97-107. 2007..Personal circumstances, beliefs, and cultural factors may all contribute to depressive symptoms in this population...
Prolonged elevations in haemostatic and rheological responses following psychological stress in low socioeconomic status men and womenAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Thromb Haemost 89:83-90. 2003..We conclude that lower SES is characterised by more prolonged elevations in procoagulant responses following psychological stress, and that these processes might contribute to increased cardiac risk...
Health behaviour, risk awareness and emotional well-being in students from Eastern Europe and Western EuropeA Steptoe
Department of Epidemiology and Public Health, University College London, UK
Soc Sci Med 53:1621-30. 2001..Unhealthy lifestyles associated with lack of information about health and behaviour, greater beliefs in uncontrollable influences, and diminished emotional well-being, may contribute to poor health status in Eastern Europe...
Locus of control and health behaviour revisited: a multivariate analysis of young adults from 18 countriesA Steptoe
Department of Epidemiology and Public Health, University College London, UK
Br J Psychol 92:659-72. 2001..Associations between health locus of control and health behaviour are of a similar magnitude to other psychosocial factors when appropriate statistical tests are employed...
Quality of life and self-rated health in relation to changes in fruit and vegetable intake and in plasma vitamins C and E in a randomised trial of behavioural and nutritional education counsellingAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Br J Nutr 92:177-84. 2004..Increases in fruit and vegetable intake and plasma vitamin levels may stimulate beneficial changes in physical health status in socio-economically deprived adults...
Acute mental stress elicits delayed increases in circulating inflammatory cytokine levelsA Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Clin Sci (Lond) 101:185-92. 2001..This study indicates that inflammatory cytokines respond to acute mental stress in humans with delayed increases, and suggest that individual differences in cytokine responses are associated with sympathetic reactivity...
Emotional triggering and low socio-economic status as determinants of depression following acute coronary syndromeA Steptoe
Department of Epidemiology and Public Health, University College London, London, UK
Psychol Med 41:1857-66. 2011..Triggering of ACS by emotional stress and low socio-economic status (SES) are predictors of adverse outcomes. We therefore investigated whether emotional triggering and low SES predict depression and anxiety following ACS...
Job control, perceptions of control, and cardiovascular activity: an analysis of ambulatory measures collected over the working dayA Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, WC1E 6BT, London, UK
J Psychosom Res 50:57-63. 2001..To assess the influence of job control as a personal characteristic, and momentary perceptions of lack of control, on blood pressure and heart rate monitored over the working day...
Educational attainment but not measures of current socioeconomic circumstances are associated with leukocyte telomere length in healthy older men and womenAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Brain Behav Immun 25:1292-8. 2011..Education may also promote problem-solving skills leading to reduced biological stress responsivity, with favorable consequences for biological aging...
Fear of dying and inflammation following acute coronary syndromeAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Eur Heart J 32:2405-11. 2011..This study evaluated the prevalence of fear of dying, associations with inflammatory responses during ACS, and later heart rate variability (HRV) and cortisol secretion...
Trends in smoking, diet, physical exercise, and attitudes toward health in European university students from 13 countries, 1990-2000Andrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, WC1E 6BT, United Kingdom
Prev Med 35:97-104. 2002..Smoking, diet, and physical exercise are key determinants of health. This study assessed changes over 10 years and their relationship to changes in health beliefs and risk awareness...
Seatbelt use, attitudes, and changes in legislation: an international studyAndrew Steptoe
Department of Epidemiology and Public Health, University College, London, United Kingdom
Am J Prev Med 23:254-9. 2002..We examined trends in seat belt use by university students from 13 European countries between 1990 and 2000, in relation to changes in legislation, attitudes, and hazardous driver behaviors...
Positive affect and psychosocial processes related to healthAndrew Steptoe
Department of Epidemiology and Public Health, University College London, UK
Br J Psychol 99:211-27. 2008..Positive affect may be beneficial for health outcomes in part because it is a component of a profile of protective psychosocial characteristics...
Socioeconomic status and stress-related biological responses over the working dayAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London, United Kingdom
Psychosom Med 65:461-70. 2003..We hypothesized that low socioeconomic status would be associated with heightened ambulatory blood pressure and cortisol output over the working day...
Positive affect, psychological well-being, and good sleepAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, United Kingdom
J Psychosom Res 64:409-15. 2008....
The influence of psychological stress and socioeconomic status on platelet activation in menAndrew Steptoe
Department of Epidemiology and Public Health, Psychobiology Group, University College London, UK
Atherosclerosis 168:57-63. 2003..Socioeconomic status is inversely associated with risk of coronary heart disease. We assessed the impact of psychological stress on leukocyte-platelet aggregates in men from higher and lower socioeconomic status groups...
Psychosocial biomarker research: integrating social, emotional and economic factors into population studies of aging and healthAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Soc Cogn Affect Neurosci 6:226-33. 2011..This will be illustrated primarily from findings from two studies conducted at University College London, the Whitehall II Study and the English Longitudinal Study of Ageing...
Behavioural counselling to increase consumption of fruit and vegetables in low income adults: randomised trialAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London WC1E 6BT
BMJ 326:855. 2003..To measure the effect of brief behavioural counselling in general practice on patients' consumption of fruit and vegetables in adults from a low income population...
The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysisAndrew Steptoe
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1 6BT, UK
Brain Behav Immun 21:901-12. 2007..The acute stress-induced inflammatory response may have implications for future health, and has become an important topic of psychoneuroimmunological research...
Positive affect measured using ecological momentary assessment and survival in older men and womenAndrew Steptoe
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom
Proc Natl Acad Sci U S A 108:18244-8. 2011..The results endorse the value of assessing experienced affect, and the importance of evaluating interventions that promote happiness in older populations...
An international comparison of tobacco smoking, beliefs and risk awareness in university students from 23 countriesAndrew Steptoe
University College London, UK
Addiction 97:1561-71. 2002....
Inflammatory cytokines, socioeconomic status, and acute stress responsivityAndrew Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1 6BT, UK
Brain Behav Immun 16:774-84. 2002..The role of inflammatory cytokines in mediating psychosocial influences on CHD is discussed...
Socioeconomic status, pathogen burden and cardiovascular disease riskA Steptoe
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Heart 93:1567-70. 2007..Cumulative pathogen burden may also predict future CHD. The hypothesis was tested that lower SES is associated with a greater pathogen burden, and that pathogen burden accounts in part for SES differences in cardiovascular risk factors...
Influence of socioeconomic status and job control on plasma fibrinogen responses to acute mental stressAndrew Steptoe
Department of Epidemiology and Public Health, University College London, United Kingdom
Psychosom Med 65:137-44. 2003..This study assessed the influence of socioeconomic status, job control, and social isolation on fibrinogen responses to acute stress...
Psychological factors associated with fruit and vegetable intake and with biomarkers in adults from a low-income neighborhoodAndrew Steptoe
Department of Epidemiology and Public Health, University College London, England
Health Psychol 22:148-55. 2003..The authors conclude that several of the psychological factors associated with self-reported intake were also related to biomarkers in this population and that these may therfore be particularly appropriate targets for intervention...
The influence of abdominal obesity and chronic work stress on ambulatory blood pressure in men and womenA Steptoe
Department of Psychology, St George s Hospital Medical School, University of London, London, UK
Int J Obes Relat Metab Disord 23:1184-91. 1999..To assess the influence of abdominal obesity and work stress (operationalised as low control over work) on ambulatory blood pressure on a working day and evening...
Acute inflammation and negative mood: mediation by cytokine activationC E Wright
Psychobiology Group, Department of Epidemiology and Public Health, University College London, London, UK
Brain Behav Immun 19:345-50. 2005..Implications for depressed mood in physical illness are discussed...
Stress-induced cytokine responses and central adiposity in young womenL Brydon
Department of Epidemiology and Public Health, Psychobiology Group, University College London, London, UK
Int J Obes (Lond) 32:443-50. 2008....
Psychological coping styles and cortisol over the day in healthy older adultsKatie O'Donnell
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Psychoneuroendocrinology 33:601-11. 2008..The results indicate that adaptive coping styles are related to low levels of cortisol over the day, suggesting that neuroendocrine pathways may partly mediate relationships between psychological coping and health...
Cortisol awakening response is elevated in acute coronary syndrome patients with type-D personalityDaisy L Whitehead
Department of Epidemiology and Public Health, Psychobiology Group, University College London, London, United Kingdom
J Psychosom Res 62:419-25. 2007..The biological pathways underpinning this relationship may include disruption of the hypothalamic-pituitary-adrenocortical (HPA) axis. We therefore assessed cortisol output in patients who had recently suffered from ACS...
Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohortSabine R Kunz-Ebrecht
University College London, Department of Epidemiology and Public Health, 1-19 Torrington Place, London WC1E 6BT, UK
Psychoneuroendocrinology 29:516-28. 2004..Cortisol output over the early part of the day may be particularly sensitive to the influence of chronic stress and its anticipation, especially in women...
The relationship between life satisfaction and health behavior: a cross-cultural analysis of young adultsNina Grant
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, WC1E 6BT, UK
Int J Behav Med 16:259-68. 2009..Positive well-being has been associated with a range of favorable health outcomes. The contribution of health-promoting behaviors is unclear...
The impact of behavioral counseling on stage of change in fat intake, physical activity, and cigarette smoking in adults at increased risk of coronary heart diseaseA Steptoe
St George s Hospital Medical School, University of London, 1 19 Tarrington Pl, London, United Kingdom
Am J Public Health 91:265-9. 2001..This study assessed stages of change in fat intake, physical activity, and cigarette smoking during a randomized controlled trial of behavioral counseling...
Functional health literacy and health-promoting behaviour in a national sample of British adultsChristian von Wagner
Cancer Reseach UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, 2 16 Torrington Place, London WC1E 6BT, UK
J Epidemiol Community Health 61:1086-90. 2007..To measure the prevalence of limited functional health literacy in the UK, and examine associations with health behaviours and self-rated health...
Physiological correlates of cognitive functioning in an elderly populationC E Wright
Psychobiology Group, Department of Epidemiology and Public Health, University College London, UK
Psychoneuroendocrinology 30:826-38. 2005..Disturbances of neuroendocrine and hemodynamic function may be related to greater vulnerability to cognitive decline...
Cortisol responses to mild psychological stress are inversely associated with proinflammatory cytokinesSabine R Kunz-Ebrecht
Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Brain Behav Immun 17:373-83. 2003..We conclude that individual variations in neuroendocrine stress responsivity may have an impact on proinflammatory cytokines, and that both high and low cortisol stress responsiveness has potentially adverse effects...
Lack of association between depressive symptoms and markers of immune and vascular inflammation in middle-aged men and womenA Steptoe
Department of Epidemiology and Public Health, University College London
Psychol Med 33:667-74. 2003....
Inflammatory and hemostatic responses to repeated mental stress: individual stability and habituation over timeMark Hamer
Psychobiology Group, Department of Epidemiology and Public Health, University College London, London, UK
Brain Behav Immun 20:456-9. 2006....
Circulating human heat shock protein 60 in the plasma of British civil servants: relationship to physiological and psychosocial stressJo Lewthwaite
Cellular Microbiology Research Group, University College London, London, UK
Circulation 106:196-201. 2002..To identify mechanisms responsible for susceptibility to CHD, specific biological markers of stress are increasingly being measured. One marker linked to susceptibility to CHD is heat shock protein (Hsp) 60...
Trends in physical activity and sedentary behaviour in adolescence: ethnic and socioeconomic differencesNaomi Henning Brodersen
Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Br J Sports Med 41:140-4. 2007..To assess developmental trends in physical activity and sedentary behaviour in British adolescents in relation to sex, ethnicity and socioeconomic status (SES)...
Work stress, socioeconomic status and neuroendocrine activation over the working daySabine R Kunz-Ebrecht
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK
Soc Sci Med 58:1523-30. 2004..Analyses of psychobiological pathways must take account of variations in exposure to chronic stressors as well as differences in responsivity to stressors...
Pain, mood and opioid medication use in sickle cell diseaseKofi A Anie
Imperial College School of Medicine, Brent Sickle Cell and Thalassaemia Center, Central Middlesex Hospital, London, UK
Hematol J 4:71-3. 2003..Patients who use opioids more frequently for sickle cell pain show more disruption of their lives, with reduced activity levels and more pessimistic mood...
Socioeconomic status, C-reactive protein, immune factors, and responses to acute mental stressNatalie Owen
Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK
Brain Behav Immun 17:286-95. 2003..Post-stress recovery was delayed in women compared with men. The results suggest that moderate inflammation and immune activation may be processes through which lower SES increases disease risk...
Arterial stiffness and inflammatory response to psychophysiological stressElizabeth Ellins
Vascular Physiology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
Brain Behav Immun 22:941-8. 2008..We conclude that individual differences in inflammatory responses to psychophysiological stress are independently related to structural changes in artery walls that reflect increased cardiovascular disease risk...
Type-D personality and cortisol in survivors of acute coronary syndromeGerard J Molloy
Department of Epidemiology and Public Health, University College London, London, UK
Psychosom Med 70:863-8. 2008..To test the hypothesis that Type-D personality is associated with elevated cortisol levels in patients 4 months after an acute coronary syndrome (ACS)...
Social support at work, heart rate, and cortisol: a self-monitoring studyO Evans
Office of National Statistics, London, England
J Occup Health Psychol 6:361-70. 2001..There were few differences between men and women, and no important occupational effects...
Family history of cardiovascular disease is associated with cardiovascular responses to stress in healthy young men and womenCaroline E Wright
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London, UK
Int J Psychophysiol 63:275-82. 2007..The findings indicate that a family history of cardiovascular disease risk influences stress responsivity which may in turn contribute to risk of future cardiovascular disorders...
Frequency of distress and fear of dying during acute coronary syndromes and consequences for adaptationDaisy L Whitehead
Department of Epidemiology and Public Health, University College London, London, United Kingdom
Am J Cardiol 96:1512-6. 2005..In conclusion, distress and fear during the initial stages of an ACS may trigger subsequent depression and anxiety, thereby promoting poorer prognosis and greater morbidity with time...
Ten-year changes in sun protection behaviors and beliefs of young adults in 13 European countriesVictoria Peacey
Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, Gower Street, London WC1E 6BT, UK
Prev Med 43:460-5. 2006..Awareness of the risk to health of unprotected sunbathing is high, but there is scope of strengthening attitudes to sunscreen use...
Pathophysiological processes underlying emotional triggering of acute cardiac eventsPhilip C Strike
Psychobiology Group, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, United Kingdom
Proc Natl Acad Sci U S A 103:4322-7. 2006....
Socioeconomic status differences in coping with a stressful medical procedureAlice E Simon
Department of Epidemiology and Public Health, University College London, UK
Psychosom Med 67:270-6. 2005..Moderately stressful experiences in everyday life do not necessarily more unfavorably affect those with fewer educational and economic resources...
The cortisol awakening response in relation to objective and subjective measures of waking in the morningSamantha Dockray
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
Psychoneuroendocrinology 33:77-82. 2008..A small minority of individuals do not show a positive CAR despite not delaying saliva sampling after waking...
Stress-induced increases in interleukin-6 and fibrinogen predict ambulatory blood pressure at 3-year follow-upLena Brydon
The Psychobiology Group, Department of Epidemiology and Public Health, University College London, UK
J Hypertens 23:1001-7. 2005..CONCLUSION: Given the important roles of interleukin-6 and fibrinogen in hypertensive pathophysiology, these results indicate that psychological stress could promote hypertension through stimulating these inflammatory proteins...
Behavioral and emotional triggers of acute coronary syndromes: a systematic review and critiquePhilip C Strike
Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Psychosom Med 67:179-86. 2005..The benefits to patients of knowledge to these processes have yet to accrue...
The contribution of gender-role orientation, work factors and home stressors to psychological well-being and sickness absence in male- and female-dominated occupational groupsOlga Evans
Office for National Statistics, London, UK
Soc Sci Med 54:481-92. 2002..Psychological traits related to socially constructed gender roles may also be relevant, and mediate in part the differences in psychological well-being between men and women...
The long-term effects of acute triggers of acute coronary syndromes on adaptation and quality of lifeMimi R Bhattacharyya
Department of Epidemiology and Public Health, University College London, London, UK
Int J Cardiol 138:246-52. 2010..A proportion of acute coronary syndromes (ACS) are thought to be triggered acutely by physical exertion, emotional stress and other stimuli. We assessed the consequences of triggering for long-term adaptation following ACS...
The relationship between carotid stiffness and circulating levels of heat shock protein 60 in middle-aged men and womenElizabeth Ellins
Vascular Physiology Unit, Institute of Child Health, University College London, UK
J Hypertens 26:2389-92. 2008..In this study, we measured the association between plasma HSP60 and carotid arterial stiffness in middle-aged men and women...
Leisure-time physical activity in university students from 23 countries: associations with health beliefs, risk awareness, and national economic developmentAnne Haase
Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
Prev Med 39:182-90. 2004..The relationship between health beliefs and behavior is robust across cultures, but health knowledge remains deficient...
How neighborhoods and physical functioning are related: the roles of neighborhood socioeconomic status, perceived neighborhood strain, and individual health risk factorsPamela J Feldman
Department of Epidemiology and Public Health, University of College London, London
Ann Behav Med 27:91-9. 2004..CONCLUSIONS: Neighborhood SES and associated perceptions of neighborhoods are associated with physical functioning to some extent through the shaping of the social and psychological experiences of individuals living within them...
Stress responsivity and socioeconomic status: a mechanism for increased cardiovascular disease risk?A Steptoe
Department of Epidemiology and Public Health, University College London, UK
Eur Heart J 23:1757-63. 2002..We hypothesized that psychobiological pathways, specifically slow recovery in blood pressure and heart rate variability following mental stress, partly mediate social inequalities in risk...
Psychological factors in leg ulceration: a case-control studyC J Moffatt
Centre for Research and Implementation of Clinical Practice, London, UK
Br J Dermatol 161:750-6. 2009..There is increasing recognition of the role that psychological status plays in the development and outcomes of chronic disease, but little understanding of its importance in chronic leg ulceration...
Natural killer cell and proinflammatory cytokine responses to mental stress: associations with heart rate and heart rate variabilityNatalie Owen
Psychobiology Group, Department of Epidemiology and Public Health, University College London, 1-19 Torrington Place, London WC1E 6BT, UK
Biol Psychol 63:101-15. 2003..We conclude that individual differences in sympathetically-driven cardiac stress responses are associated with NK and proinflammatory cytokine responses to psychological stress...
Greater cardiovascular responses to laboratory mental stress are associated with poor subsequent cardiovascular risk status: a meta-analysis of prospective evidenceYoichi Chida
Department of Epidemiology and Public Health, University College London, London, United Kingdom
Hypertension 55:1026-32. 2010....
Low-intensity physical activity is associated with reduced risk of incident type 2 diabetes in older adults: evidence from the English Longitudinal Study of AgeingP Demakakos
Department of Epidemiology and Public Health, University College London, London, UK
Diabetologia 53:1877-85. 2010..We examined whether small amounts of low-intensity physical activity were associated with reduced risk of developing type 2 diabetes in a national sample of people aged 50 years and over...
