H A F Stephens

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint HIV-1 diversity versus HLA class I polymorphism
    Henry A F Stephens
    Institute of Urology and Nephrology, University College London, The Middlesex Hospital, Mortimer Street, London, UK
    Trends Immunol 26:41-7. 2005
  2. doi request reprint Immunogenetic surveillance of HIV/AIDS
    Henry A F Stephens
    UCL Centre for Nephrology and the Anthony Nolan Laboratories, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, UK
    Infect Genet Evol 12:1481-91. 2012
  3. ncbi request reprint MHC haplotypes, MICA genes and the 'wonderland' of NK receptor polymorphism
    Henry A F Stephens
    Institute of Urology and Nephrology, University College London, The Middlesex Hospital, 48 Riding House Street, London, UK
    Trends Immunol 23:385-6. 2002
  4. ncbi request reprint HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais
    H A F Stephens
    Institute of Urology and Nephrology, University College, London, UK
    Tissue Antigens 60:309-18. 2002
  5. ncbi request reprint MICA and MICB genes: can the enigma of their polymorphism be resolved?
    H A Stephens
    Institute of Urology and Nephrology, University College London, The Middlesex Hospital, 48 Riding House Street, London, UK, W1W 7EY
    Trends Immunol 22:378-85. 2001
  6. ncbi request reprint A comparison of molecular HLA-DR and DQ allele profiles forming DR51-, DR52-, and DR53-related haplotypes in five ethnic Thai populations from mainland southeast Asia
    H A Stephens
    Department of Transfusion Medicine, Siriraj Hospital and Medical School, Mahidol University, Bangkok, Thailand
    Hum Immunol 61:1039-47. 2000
  7. doi request reprint HLA and other gene associations with dengue disease severity
    H A F Stephens
    Centre for Nephrology and The Anthony Nolan Trust, University College London, The Royal Free Hospital Campus, Rowland Hill Street, London, NW3 2PF, UK
    Curr Top Microbiol Immunol 338:99-114. 2010
  8. ncbi request reprint Associations of HLA class II alleles with pulmonary tuberculosis in Thais
    S Vejbaesya
    Department of Transfusion Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Eur J Immunogenet 29:431-4. 2002
  9. ncbi request reprint Distribution of natural killer cell immunoglobulin-like receptor sequences in three ethnic groups
    P J Norman
    South Thames Tissue Typing, Guy s Hospital, London, UK
    Immunogenetics 52:195-205. 2001
  10. ncbi request reprint Natural killer cell immunoglobulin-like receptor (KIR) locus profiles in African and South Asian populations
    P J Norman
    South Thames Tissue Typing, Guy s Hospital, London, UK
    Genes Immun 3:86-95. 2002

Detail Information

Publications21

  1. ncbi request reprint HIV-1 diversity versus HLA class I polymorphism
    Henry A F Stephens
    Institute of Urology and Nephrology, University College London, The Middlesex Hospital, Mortimer Street, London, UK
    Trends Immunol 26:41-7. 2005
    ..HLA-A11 displays unique peptide-binding properties and is recognized by natural killer cells utilizing the inhibitory killer Ig-like receptor 3DL2 in a peptide-dependent manner...
  2. doi request reprint Immunogenetic surveillance of HIV/AIDS
    Henry A F Stephens
    UCL Centre for Nephrology and the Anthony Nolan Laboratories, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, UK
    Infect Genet Evol 12:1481-91. 2012
    ....
  3. ncbi request reprint MHC haplotypes, MICA genes and the 'wonderland' of NK receptor polymorphism
    Henry A F Stephens
    Institute of Urology and Nephrology, University College London, The Middlesex Hospital, 48 Riding House Street, London, UK
    Trends Immunol 23:385-6. 2002
  4. ncbi request reprint HLA-A and -B allele associations with secondary dengue virus infections correlate with disease severity and the infecting viral serotype in ethnic Thais
    H A F Stephens
    Institute of Urology and Nephrology, University College, London, UK
    Tissue Antigens 60:309-18. 2002
    ..These results confirm that classical HLA class I alleles are associated with the clinical outcome of exposure to dengue virus, in previously exposed and immunologically primed individuals...
  5. ncbi request reprint MICA and MICB genes: can the enigma of their polymorphism be resolved?
    H A Stephens
    Institute of Urology and Nephrology, University College London, The Middlesex Hospital, 48 Riding House Street, London, UK, W1W 7EY
    Trends Immunol 22:378-85. 2001
    ..MICA molecules appear to be highly flexible and polymorphic, although the functional relevance and implications of their polymorphism have yet to be fully discerned...
  6. ncbi request reprint A comparison of molecular HLA-DR and DQ allele profiles forming DR51-, DR52-, and DR53-related haplotypes in five ethnic Thai populations from mainland southeast Asia
    H A Stephens
    Department of Transfusion Medicine, Siriraj Hospital and Medical School, Mahidol University, Bangkok, Thailand
    Hum Immunol 61:1039-47. 2000
    ....
  7. doi request reprint HLA and other gene associations with dengue disease severity
    H A F Stephens
    Centre for Nephrology and The Anthony Nolan Trust, University College London, The Royal Free Hospital Campus, Rowland Hill Street, London, NW3 2PF, UK
    Curr Top Microbiol Immunol 338:99-114. 2010
    ..Further analysis of the genetic basis of severe DENV disease in different at risk populations may contribute to the development of new preventative and therapeutic interventions...
  8. ncbi request reprint Associations of HLA class II alleles with pulmonary tuberculosis in Thais
    S Vejbaesya
    Department of Transfusion Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Eur J Immunogenet 29:431-4. 2002
    ..02 and P = 0.01, respectively). Our results suggest that HLA-DQB1*0502 may be involved in the development of pulmonary tuberculosis, whereas HLA-DQA1*0601 and DQB1*0301 may be associated with protection against tuberculosis...
  9. ncbi request reprint Distribution of natural killer cell immunoglobulin-like receptor sequences in three ethnic groups
    P J Norman
    South Thames Tissue Typing, Guy s Hospital, London, UK
    Immunogenetics 52:195-205. 2001
    ..The A haplotype was always the most prevalent, but the ratio of A to B varied between populations. The frequency of B haplotype was highest in the Palestinians and lowest in the Thais (Pc<0.0001)...
  10. ncbi request reprint Natural killer cell immunoglobulin-like receptor (KIR) locus profiles in African and South Asian populations
    P J Norman
    South Thames Tissue Typing, Guy s Hospital, London, UK
    Genes Immun 3:86-95. 2002
    ..0001 to < 0.004). Furthermore, gene frequency independent deviances in the linkage disequilibrium were apparent between populations...
  11. ncbi request reprint Does the polymorphism of MHC class II promoters matter?
    N A Mitchison
    Department of Immunology, Windeyer Institute of Medical Science, 46 Cleveland Street, London W1T 4JF, UK
    Cell Immunol 233:162-5. 2005
    ....
  12. doi request reprint Two novel MICA alleles, MICA*054 and MICA*056
    S T Cox
    The Anthony Nolan Research Institute and Trust, The Royal Free Hospital, London, UK
    Tissue Antigens 73:85-7. 2009
    ..MICA*056 has a nucleotide substitution at position 758 of G to C resulting in the substitution of tryptophan for serine at codon 230, also in the alpha-3 domain...
  13. ncbi request reprint HLA-DR and -DQ associations with melioidosis
    T Dharakul
    Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Hum Immunol 59:580-6. 1998
    ..In contrast, no HLA association was observed in localized melioidosis or melioidosis with diabetes mellitus. These findings provide the suggestive evidence of an immunogenetic basis of certain aspects of melioidosis...
  14. ncbi request reprint Towards a molecular phototyping system for allelic variants of MICA, encoded by polymorphisms in exons 2, 3 and 4 of MHC class I chain-related genes
    H A Stephens
    South Thames Tissue Typing Laboratory, Guys Hospital, Institute of Urology and Nephrology, University College London Medical School, UK
    Tissue Antigens 53:167-74. 1999
    ....
  15. ncbi request reprint SNP haplotypes and allele frequencies show evidence for disruptive and balancing selection in the human leukocyte receptor complex
    Paul J Norman
    Clinical Transplantation Laboratory, Guy s Hospital, 3rd Floor New Guy s House, St Thomas Street, London, SE1 9RT, UK
    Immunogenetics 56:225-37. 2004
    ..The different natural selection pressures acting on each locus may have contributed to a lack of linkage disequilibrium between them...
  16. ncbi request reprint High resolution molecular phototyping of MICA and MICB alleles using sequence specific primers
    Robert W M Collins
    South Thames Tissue Typing, Guy s Hospital, London, United Kingdom
    Hum Immunol 63:783-94. 2002
    ....
  17. ncbi request reprint Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans
    Paul J Norman
    Department of Structural Biology, Stanford University School of Medicine, Stanford, California 94305, USA
    Nat Genet 39:1092-9. 2007
    ..Natural killer cells express the dominant KIR3DL1 at a high frequency and with high surface density, providing strong responses to cells perturbed in Bw4 expression...
  18. ncbi request reprint A comparison of HLA-DR and -DQ allele and haplotype frequencies in Trinidadian populations of African, South Asian, and mixed ancestry
    Christine V F Carrington
    Department of Pre Clinical Sciences, Faculty of Medical Sciences, University of the West Indies, St Augustine, Trinidad
    Hum Immunol 63:1045-54. 2002
    ..Trinidad South Asians displayed similar allele frequencies and associations to other populations from Northern India...
  19. ncbi request reprint Molecular typing of the MHC class I chain-related gene locus
    R W M Collins
    Guy s and St Thomas s Hospitals, London, United Kingdom
    Methods Mol Biol 210:305-21. 2003
  20. ncbi request reprint DNA sequence variation and molecular genotyping of natural killer leukocyte immunoglobulin-like receptor, LILRA3
    Paul J Norman
    Clinical Transplantation Laboratory, Guy s Hospital, 3rd Floor New Guy s House, St Thomas Street, SE1 9RT, London, UK
    Immunogenetics 55:165-71. 2003
    ..Six alleles were present in this group but they were unevenly distributed, as three alleles accounted for 88% of the studied chromosomes...
  21. ncbi request reprint T cell responses to an HLA-B*07-restricted epitope on the dengue NS3 protein correlate with disease severity
    Iva Zivna
    Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Immunol 168:5959-65. 2002
    ..These findings support the hypothesis that activation of DV-specific CD8(+) T cells plays an important role in the pathogenesis of DHF...