C A Staton

Summary

Affiliation: University of Sheffield
Country: UK

Publications

  1. doi request reprint Class 3 semaphorins and their receptors in physiological and pathological angiogenesis
    Carolyn A Staton
    Microcirculation Research Group, Academic Unit of Surgical Oncology, Faculty of Medicine, Dentistry and Health University of Sheffield, Sheffield S10 2RX, UK
    Biochem Soc Trans 39:1565-70. 2011
  2. pmc Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation
    Danny C W Yu
    Department of Oncology, School of Medicine and Biomedical Sciences, University of Sheffield, Royal Hallamshire Hospital, Sheffield, S10 2JF, UK
    Mol Cancer 9:276. 2010
  3. doi request reprint Expression of class 3 semaphorins and their receptors in human breast neoplasia
    Carolyn A Staton
    Academic Units of Surgical Oncology Pathology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK
    Histopathology 59:274-82. 2011
  4. doi request reprint Angiopoietins 1 and 2 and Tie-2 receptor expression in human ductal breast disease
    Carolyn A Staton
    Academic Unit of Surgical Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK
    Histopathology 59:256-63. 2011
  5. doi request reprint Angiopoietin-1, angiopoietin-2 and Tie-2 receptor expression in human dermal wound repair and scarring
    C A Staton
    Microcirculation Research Group, Academic Unit of Surgical Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield S10 2RX, UK
    Br J Dermatol 163:920-7. 2010
  6. doi request reprint Angiogenesis, vascular endothelial growth factor and its receptors in human surgical wounds
    I Kumar
    Academic Unit of Surgical Oncology, University of Sheffield Medical School, Sheffield, UK
    Br J Surg 96:1484-91. 2009
  7. pmc Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease
    J E Bluff
    Microcirculation Research Group, Academic Unit of Surgical Oncology, University of Sheffield Medical School, Sheffield, South Yorkshire, UK
    Br J Cancer 101:666-72. 2009
  8. doi request reprint Anti-tissue factor short hairpin RNA inhibits breast cancer growth in vivo
    J E Bluff
    Department of Oncology, University of Sheffield Medical School, Sheffield, South Yorkshire, S10 2RX, UK
    Breast Cancer Res Treat 128:691-701. 2011
  9. pmc Angiogenesis in pre-malignant conditions
    S R Menakuru
    Microcirculation Research Group, Academic Surgical Oncology Unit, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield S10 2JF, UK
    Br J Cancer 99:1961-6. 2008
  10. ncbi request reprint Neuropilins in physiological and pathological angiogenesis
    C A Staton
    Microcirculation Research Group, Academic Unit of Surgical Oncology, University of Sheffield, Sheffield S10 2JF, UK
    J Pathol 212:237-48. 2007

Collaborators

Detail Information

Publications11

  1. doi request reprint Class 3 semaphorins and their receptors in physiological and pathological angiogenesis
    Carolyn A Staton
    Microcirculation Research Group, Academic Unit of Surgical Oncology, Faculty of Medicine, Dentistry and Health University of Sheffield, Sheffield S10 2RX, UK
    Biochem Soc Trans 39:1565-70. 2011
    ..The present review specifically focuses on recent evidence for this role in both physiological and pathological angiogenesis...
  2. pmc Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation
    Danny C W Yu
    Department of Oncology, School of Medicine and Biomedical Sciences, University of Sheffield, Royal Hallamshire Hospital, Sheffield, S10 2JF, UK
    Mol Cancer 9:276. 2010
    ..We have previously shown that butyrate, a naturally occurring histone deacetylase inhibitor (HDACi) produced by fermentation of fibre in the colon, causes apoptosis of colon cancer cell lines...
  3. doi request reprint Expression of class 3 semaphorins and their receptors in human breast neoplasia
    Carolyn A Staton
    Academic Units of Surgical Oncology Pathology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK
    Histopathology 59:274-82. 2011
    ..This study aimed to identify the involvement of class 3 semaphorins (Sema3) and receptors, neuropilins (Np1 and Np2) and plexins (A1-A4) in breast cancer development and angiogenesis...
  4. doi request reprint Angiopoietins 1 and 2 and Tie-2 receptor expression in human ductal breast disease
    Carolyn A Staton
    Academic Unit of Surgical Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, UK
    Histopathology 59:256-63. 2011
    ..This study aimed to identify the involvement of the angiopoietin/Tie-2 receptor system in breast cancer development, progression, metastasis and angiogenesis...
  5. doi request reprint Angiopoietin-1, angiopoietin-2 and Tie-2 receptor expression in human dermal wound repair and scarring
    C A Staton
    Microcirculation Research Group, Academic Unit of Surgical Oncology, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield S10 2RX, UK
    Br J Dermatol 163:920-7. 2010
    ..However, the precise contribution of this system to angiogenesis and the mechanisms of vascular maturation and remodelling in human tissue repair have yet to be elucidated...
  6. doi request reprint Angiogenesis, vascular endothelial growth factor and its receptors in human surgical wounds
    I Kumar
    Academic Unit of Surgical Oncology, University of Sheffield Medical School, Sheffield, UK
    Br J Surg 96:1484-91. 2009
    ..This study examined the spatial and temporal expression of these factors in relation to angiogenesis in surgical wounds...
  7. pmc Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease
    J E Bluff
    Microcirculation Research Group, Academic Unit of Surgical Oncology, University of Sheffield Medical School, Sheffield, South Yorkshire, UK
    Br J Cancer 101:666-72. 2009
    ..The precise timing of the angiogenic switch and the role of angiogenesis in the development of breast malignancy is currently unknown...
  8. doi request reprint Anti-tissue factor short hairpin RNA inhibits breast cancer growth in vivo
    J E Bluff
    Department of Oncology, University of Sheffield Medical School, Sheffield, South Yorkshire, S10 2RX, UK
    Breast Cancer Res Treat 128:691-701. 2011
    ..004; P < 0.008). These data suggest that TF has a direct effect on primary breast cancer growth and angiogenesis, and that specific inhibition of the TF-signalling pathway has potential for the treatment of primary breast cancer...
  9. pmc Angiogenesis in pre-malignant conditions
    S R Menakuru
    Microcirculation Research Group, Academic Surgical Oncology Unit, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield S10 2JF, UK
    Br J Cancer 99:1961-6. 2008
    ..Understanding the mechanisms inducing angiogenesis in these lesions and identification of those important in human tumourigenesis are necessary to develop translational strategies that will help realise the goal of angioprevention...
  10. ncbi request reprint Neuropilins in physiological and pathological angiogenesis
    C A Staton
    Microcirculation Research Group, Academic Unit of Surgical Oncology, University of Sheffield, Sheffield S10 2JF, UK
    J Pathol 212:237-48. 2007
    ..This review details the current evidence for the role of neuropilins in angiogenesis, and suggests future research directions that may enhance our understanding of the mechanisms of action of this unique family of proteins...
  11. pmc A novel fragment derived from the beta chain of human fibrinogen, beta43-63, is a potent inhibitor of activated endothelial cells in vitro and in vivo
    E Krajewska
    Tumor Targeting Group, University of Sheffield Medical School, Sheffield S10 2RX, UK
    Br J Cancer 102:594-601. 2010
    ..We therefore investigated which region of FgnE was mediating vessel cytotoxicity...