R T Staff
Affiliation: University of Aberdeen
- Changes in the rCBF images of patients with Alzheimer's disease receiving Donepezil therapyR T Staff
Department of Bio medical Physics, University of Aberdeen, UK
Nucl Med Commun 21:37-41. 2000..4%. However, some patients showed a slight decrease in blood flow. When the data were analysed in terms of regional cerebral blood flow, we found that the most significant increase in blood flow occurred in the frontal lobes (P = 0.02)...
- Shape analysis of 123I-N-omega-fluoropropyl-2-beta-carbomethoxy-3beta-(4-iodophenyl) nortropane single-photon emission computed tomography images in the assessment of patients with parkinsonian syndromesRoger T Staff
Medical Physics, Aberdeen Royal Infirmary, NHS Grampian, University of Aberdeen, UK
Nucl Med Commun 30:194-201. 2009....
- Generality and specificity in cognitive aging: a volumetric brain analysisRoger T Staff
Department of Bio medical Physics, Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZD, UK
Neuroimage 30:1433-40. 2006..To investigate whether, in old age, brain volume differences are associated with age-related change in general mental ability and/or specific cognitive abilities...
- What provides cerebral reserve?Roger T Staff
Department of Bio Medical Physics and Bioengineering, University of Aberdeen and Aberdeen Royal Infirmary, Foresterhill, UK
Brain 127:1191-9. 2004..We conclude that the intellectual challenges experienced during life, such as education and occupation, accumulate reserve and allow cognitive function to be maintained in old age...
- Dynamic contrast enhanced MRI of the axilla in women with breast cancer: comparison with pathology of excised nodesA D Murray
Department of Radiology, University of Aberdeen and Aberdeen Royal Infirmary, Foresterhill, Aberdeen AB25 2ZN, UK
Br J Radiol 75:220-8. 2002....
- The biological correlates of macroscopic breast tumour structure measured using fractal analysis in patients undergoing neoadjuvant chemotherapyP Di Giovanni
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, UK
Breast Cancer Res Treat 133:1199-206. 2012....
- Accuracy of T1 measurement in dynamic contrast-enhanced breast MRI using two- and three-dimensional variable flip angle fast low-angle shotJ A Brookes
Department of Bio Medical Physics and Bio Engineering, University of Aberdeen, Foresterhill, United Kingdom
J Magn Reson Imaging 9:163-71. 1999..Rigorous quality assurance programs with calibrated phantoms are thus recommended, to verify the accuracy with which T1 measurements are obtained...
- Nurturing syndrome: a form of pathological bereavement with delusions in Alzheimer's diseaseA Venneri
Department of Psychology, University of Aberdeen, UK
Neuropsychologia 38:213-24. 2000....
- The effects of renal variation upon measurements of perfusion and leakage volume in breast tumoursT S Ahearn
Department of Bio medical Physics, University of Aberdeen, Grampian University Hospitals NHS Trust, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
Phys Med Biol 49:2041-51. 2004....
- The use of the Levenberg-Marquardt curve-fitting algorithm in pharmacokinetic modelling of DCE-MRI dataT S Ahearn
Department of Bio medical Physics, University of Aberdeen and Grampian University Hospitals NHS Trust, Foresterhill, Aberdeen AB25 2ZD, UK
Phys Med Biol 50:N85-92. 2005..We conclude that the use of a single starting point when fitting compartmental modelling data such as this produces unsafe results and we recommend the use of multiple start points in order to find the global minima...
- Baseline MRI delivery characteristics predict change in invasive ductal breast carcinoma PET metabolism as a result of primary chemotherapy administrationS I K Semple
Department of Radiology, University of Aberdeen, Scotland, UK
Ann Oncol 17:1393-8. 2006..Reduction in (18)F-FDG PET metabolism has previously been shown to correlate with histological response to primary chemotherapy...
- The use of FDG-PET in assessing axillary lymph node status in breast cancer: a systematic review and meta-analysis of the literatureRebecca Peare
Department of Nuclear Medicine, Aberdeen Royal, Infirmary, Aberdeen AB25 2ZD, UK
Breast Cancer Res Treat 123:281-90. 2010..Moreover, the additional benefit of an assessment of distal metastatic spread provided by FDG-PET requires further investigation...
- Comparison of methods for quantification of transient ischaemic dilation in myocardial perfusion SPETR A Peace
Department of Bio Medical Physics and Bio Engineering, University of Aberdeen, Grampian University Hospitals Trust, Foresterhill, UK
Nucl Med Commun 21:971-6. 2000..0005). TID measured by all the algorithms is an indicator of severe coronary disease (P < 0.05). The algorithms compared provide a repeatable, quantitative and specific measure of the TID ratio...
- Plasma vitamin C, cholesterol and homocysteine are associated with grey matter volume determined by MRI in non-demented old peopleL J Whalley
Clinical Research Centre, Department of Mental Health, University of Aberdeen, Royal Cornhill Hospital, UK
Neurosci Lett 341:173-6. 2003..These data are consistent with the putative benefits of dietary vitamin C and folate intake and the role of cholesterol in age related neurodegeneration...
- The use of SPAMM to assess spatial distortion due to static field inhomogeneity in dental MRIR R Bridcut
Department of Bio Medical Physics and Bio Engineering, University of Aberdeen, Foresterhill, UK
Phys Med Biol 46:1357-67. 2001..SPAMM may thus be used to provide a qualitative estimate of the accuracy of the MRI image when planning dental implants...
- Monitoring primary breast cancer throughout chemotherapy using FDG-PETGarry M McDermott
School of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
Breast Cancer Res Treat 102:75-84. 2007..The purpose was to determine whether there is an optimal method for defining tumour volume and an optimal imaging time for predicting pathologic chemotherapy response...
- Brain white matter hyperintensities: relative importance of vascular risk factors in nondemented elderly peopleAlison D Murray
Department of Radiology, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland
Radiology 237:251-7. 2005....
- Cerebral blood flow and cognitive responses to rivastigmine treatment in Alzheimer's diseaseAnnalena Vennerica
Department of Psychology, University of Aberdeen, UK
Neuroreport 13:83-7. 2002..Longitudinal assessment with repeated imaging offers a method of better understanding the effects of cholinesterase inhibition on the AD brain...
- The relationship between vascular and metabolic characteristics of primary breast tumoursScott I K Semple
Department of Radiology, University of Aberdeen, Lilian Sutton Building, AB252ZD Aberdeen, Scotland, UK
Eur Radiol 14:2038-45. 2004..MRI and PET provide methods of assessing breast tumour vascularity and metabolism in vivo using the exchange rate constants of dynamic MRI, and DUR of PET, respectively, these measures being related but not equivalent...
- Is retaining the youthful functional anatomy underlying speed of information processing a signature of successful cognitive ageing? An event-related fMRI study of inspection time performanceGordon D Waiter
Department of Radiology, College of Life Sciences and Medicine, University of Aberdeen, UK
Neuroimage 41:581-95. 2008..The relative preservation of complex reasoning skills in old age may be associated with the preservation of the neural networks that underpin fundamental information processing in youth...
- Predicting response using MRI enhancement characteristics when response is determined using change in enhancement pattern: a potential for bias?Roger T Staff
Breast Cancer Res Treat 97:111. 2006
- Cerebral white matter abnormalities and lifetime cognitive change: a 67-year follow-up of the Scottish Mental Survey of 1932Ian J Deary
Department of Psychology, University of Edinburgh, Scotland
Psychol Aging 18:140-8. 2003..Some of this effect might be due to hypertension. This contribution is independent of mental function in early life and is associated with general cognitive ability...