Vlastimil Srsen

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation
    Vlastimil Srsen
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, King s Buildings, Edinburgh, UK
    BMC Cell Biol 10:28. 2009
  2. pmc The nuclear envelope proteome differs notably between tissues
    Nadia Korfali
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK
    Nucleus 3:552-64. 2012
  3. pmc Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations
    Gavin S Wilkie
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom
    Mol Cell Proteomics 10:M110.003129. 2011
  4. pmc Nuclei of non-muscle cells bind centrosome proteins upon fusion with differentiating myoblasts
    Xavier Fant
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 4:e8303. 2009
  5. pmc A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal
    Nadia Korfali
    The Wellcome Trust Centre for Cell Biology and Institute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 6:e18762. 2011
  6. pmc The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture
    Nadia Korfali
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH93JR, United Kingdom
    Mol Cell Proteomics 9:2571-85. 2010
  7. doi request reprint Nuclear envelope influences on cell-cycle progression
    Vlastimil Srsen
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, U K
    Biochem Soc Trans 39:1742-6. 2011
  8. pmc Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope
    Poonam Malik
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK
    Cell Mol Life Sci 67:1353-69. 2010
  9. pmc Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle
    Vlastimil Srsen
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, Scotland, UK
    J Cell Biol 174:625-30. 2006

Collaborators

Detail Information

Publications10

  1. pmc Centrosome proteins form an insoluble perinuclear matrix during muscle cell differentiation
    Vlastimil Srsen
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, King s Buildings, Edinburgh, UK
    BMC Cell Biol 10:28. 2009
    ..The exact timing of this event, and the underlying molecular mechanisms are still poorly understood...
  2. pmc The nuclear envelope proteome differs notably between tissues
    Nadia Korfali
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK
    Nucleus 3:552-64. 2012
    ..The high tissue specificity in the nuclear envelope likely underlies the complex disease pathologies and argues that all organelle proteomes warrant re-examination in multiple tissues...
  3. pmc Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations
    Gavin S Wilkie
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, United Kingdom
    Mol Cell Proteomics 10:M110.003129. 2011
    ....
  4. pmc Nuclei of non-muscle cells bind centrosome proteins upon fusion with differentiating myoblasts
    Xavier Fant
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 4:e8303. 2009
    ..Concomitantly, proteins of the centrosome relocalize from the pericentriolar material to the outer surface of the nucleus. The mechanisms that govern this relocalization are largely unknown...
  5. pmc A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal
    Nadia Korfali
    The Wellcome Trust Centre for Cell Biology and Institute of Cell Biology, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 6:e18762. 2011
    ....
  6. pmc The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture
    Nadia Korfali
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH93JR, United Kingdom
    Mol Cell Proteomics 9:2571-85. 2010
    ....
  7. doi request reprint Nuclear envelope influences on cell-cycle progression
    Vlastimil Srsen
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, U K
    Biochem Soc Trans 39:1742-6. 2011
    ..These contributions come from both inner and outer nuclear membrane NETs and appear to operate through several distinct mechanisms ranging from sequestration of gene-regulatory proteins to activating kinase cascades...
  8. pmc Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope
    Poonam Malik
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, UK
    Cell Mol Life Sci 67:1353-69. 2010
    ..This study expands by a factor of three the number of liver NETs analyzed, bringing the total confirmed to 31, and shows that several have multiple mechanisms for nuclear envelope retention...
  9. pmc Inhibition of centrosome protein assembly leads to p53-dependent exit from the cell cycle
    Vlastimil Srsen
    Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3JR, Scotland, UK
    J Cell Biol 174:625-30. 2006
    ..Inhibition of p38 mitogen-activated protein kinase rescued cell cycle activity after centrosome protein depletion, indicating that p53 is activated by the p38 stress pathway...