Lewis Spitz

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Peter Paul Rickham
    Lewis Spitz
    Paediatric Surgery, Hospital for Children, Great Ormond Street, WC1N3JH, London, United Kingdom
    Pediatr Surg Int 19:753-4. 2004
  2. ncbi request reprint Esophageal atresia. Lessons I have learned in a 40-year experience
    Lewis Spitz
    Institute of Child Health, University College, London Great Ormond Street Hospital for Children NHS Trust, London WC1 N3JH, UK
    J Pediatr Surg 41:1635-40. 2006
  3. pmc Oesophageal atresia
    Lewis Spitz
    Department of Paediatric Surgery, Institute of Child Health, University College, London, UK
    Orphanet J Rare Dis 2:24. 2007
  4. ncbi request reprint Factors predicting failure of redo Nissen fundoplication in children
    Maurizio Pacilli
    Institute of Child Health and Great Ormond Street Hospital for Children, University College London, London, UK
    Pediatr Surg Int 23:499-503. 2007
  5. doi request reprint Surgical outcomes of esophageal atresia without fistula for 24 years at a single institution
    Andrew J A Holland
    Department of Pediatric Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, University College London, London, UK
    J Pediatr Surg 44:1928-32. 2009
  6. doi request reprint Duhamel pull-through for Hirschsprung disease: a comparison of open and laparoscopic techniques
    Shireen A Nah
    Department of General Surgery, Great Ormond Street Hospital and UCL Institute of Child Health, London, UK
    J Pediatr Surg 47:308-12. 2012
  7. ncbi request reprint Cardiac and renal mitochondria respond differently to hydrogen peroxide in suckling rats
    Koji Fukumoto
    Department of Paediatric Surgery, Institute of Child Health, London WC1N 1EH, UK
    J Surg Res 113:146-50. 2003
  8. ncbi request reprint Tyrosine nitration of carnitine palmitoyl transferase I during endotoxaemia in suckling rats
    Koji Fukumoto
    Department of Paediatric Surgery, Institute of Child Health, 30, Guilford Street, London WC1N 1EH, UK
    Biochim Biophys Acta 1683:1-6. 2004
  9. ncbi request reprint Information on the World Wide Web--how useful is it for parents?
    Nurain Z Sim
    Department of Paediatric Surgery, Great Ormond Street Hospital, London WC1N 3JH, UK
    J Pediatr Surg 42:305-12. 2007
  10. ncbi request reprint Imaging of conjoined twins
    Kieran McHugh
    Department of Radiology, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK
    Pediatr Radiol 36:899-910; quiz 1002-3. 2006

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Peter Paul Rickham
    Lewis Spitz
    Paediatric Surgery, Hospital for Children, Great Ormond Street, WC1N3JH, London, United Kingdom
    Pediatr Surg Int 19:753-4. 2004
  2. ncbi request reprint Esophageal atresia. Lessons I have learned in a 40-year experience
    Lewis Spitz
    Institute of Child Health, University College, London Great Ormond Street Hospital for Children NHS Trust, London WC1 N3JH, UK
    J Pediatr Surg 41:1635-40. 2006
    ..The incidence and treatment of early and late complications is discussed...
  3. pmc Oesophageal atresia
    Lewis Spitz
    Department of Paediatric Surgery, Institute of Child Health, University College, London, UK
    Orphanet J Rare Dis 2:24. 2007
    ..Infants weighing over 1500 g and having no major cardiac problem should have a near 100% survival, while the presence of one of the risk factors reduces survival to 80% and further to 30-50% in the presence of both risk factors...
  4. ncbi request reprint Factors predicting failure of redo Nissen fundoplication in children
    Maurizio Pacilli
    Institute of Child Health and Great Ormond Street Hospital for Children, University College London, London, UK
    Pediatr Surg Int 23:499-503. 2007
    ..Redo Nissen fundoplication has a high failure rate. Risk factors are open fundoplication at first operation and neurological impairment. Redo fundoplication after primary laparoscopic Nissen has a lower risk of failure...
  5. doi request reprint Surgical outcomes of esophageal atresia without fistula for 24 years at a single institution
    Andrew J A Holland
    Department of Pediatric Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, University College London, London, UK
    J Pediatr Surg 44:1928-32. 2009
    ..The aim of the study was to evaluate the surgical outcome of esophageal atresia (EA) without fistula for 24 years at a single tertiary center for pediatric surgery...
  6. doi request reprint Duhamel pull-through for Hirschsprung disease: a comparison of open and laparoscopic techniques
    Shireen A Nah
    Department of General Surgery, Great Ormond Street Hospital and UCL Institute of Child Health, London, UK
    J Pediatr Surg 47:308-12. 2012
    ..Various pull-through techniques, both open and laparoscopic, have been performed for Hirschsprung disease. Our study compares open and laparoscopic Duhamel pull-through...
  7. ncbi request reprint Cardiac and renal mitochondria respond differently to hydrogen peroxide in suckling rats
    Koji Fukumoto
    Department of Paediatric Surgery, Institute of Child Health, London WC1N 1EH, UK
    J Surg Res 113:146-50. 2003
    ..Hydrogen peroxide (H(2)O(2)), a major mediator of sepsis, inhibits liver metabolism. Our aim was to determine the effects of H(2)O(2) on neonatal renal and cardiac oxidative metabolism...
  8. ncbi request reprint Tyrosine nitration of carnitine palmitoyl transferase I during endotoxaemia in suckling rats
    Koji Fukumoto
    Department of Paediatric Surgery, Institute of Child Health, 30, Guilford Street, London WC1N 1EH, UK
    Biochim Biophys Acta 1683:1-6. 2004
    ..5 M dithionite, during immunoprecipitation, greatly decreased immunopositivity for M- and L-CPTI on WB. M-CPTI appears to be a novel target for peroxynitrite during endotoxaemia, which would alter myocardial substrate selection...
  9. ncbi request reprint Information on the World Wide Web--how useful is it for parents?
    Nurain Z Sim
    Department of Paediatric Surgery, Great Ormond Street Hospital, London WC1N 3JH, UK
    J Pediatr Surg 42:305-12. 2007
    ..An enormous amount of information about pediatric surgical conditions is available on the World Wide Web (www). Our aim was to ascertain how many parents accessed the www and how useful they found the exercise...
  10. ncbi request reprint Imaging of conjoined twins
    Kieran McHugh
    Department of Radiology, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK
    Pediatr Radiol 36:899-910; quiz 1002-3. 2006
    ..Planning of postnatal surgical separation is aided by accurate preoperative imaging which, depending on the conjoined area, will encompass many imaging modalities, but often relies heavily on CT scanning...
  11. pmc Surgery for conjoined twins
    Lewis Spitz
    Department of Paediatric Surgery, Institute of Child Health, and Great Ormond Street Children s Hospital, London, UK
    Ann R Coll Surg Engl 85:230-5. 2003
  12. doi request reprint A historical vignette: gastroschisis
    Lewis Spitz
    Pediatric Surgery, Institute of Child Health and Great Ormond Street Hospital, London
    J Pediatr Surg 43:1396-7. 2008
    ..Among this collection is a fetus demonstrating a gastroschisis anomaly that had gone unrecognized for almost 200 years...
  13. ncbi request reprint Surgery of persistent hyperinsulinaemic hypoglycaemia
    Keith J Lindley
    The Institute of Child Health, University College London, London, UK
    Semin Neonatol 8:259-65. 2003
    ..Di-HI is only managed by surgery if combination drug therapies are unable to prevent hypoglycaemia. Pancreatic beta-cell dysfunction persists following subtotal pancreatectomy of di-HI...
  14. ncbi request reprint Moderate hypothermia protects against systemic oxidative stress in a rat model of intestinal ischemia and reperfusion injury
    Giorgio Stefanutti
    Department of Paediatric Surgery, Institute of Child Health, London WC1N 1EH, United Kingdom
    Shock 24:159-64. 2005
    ..However, whether these effects persist after rewarming is unknown...
  15. doi request reprint Gastric transposition in children
    Lewis Spitz
    Department of Paediatric Surgery, Institute of Child Health, University College London, London, United Kingdom
    Semin Pediatr Surg 18:30-3. 2009
    ..To analyze the outcome in 192 children (116 males, 76 females) undergoing transposition since 1981...
  16. ncbi request reprint Conjoined twins
    Lewis Spitz
    Institute of Child Health and Great Ormond Street Hospital, London, UK
    Prenat Diagn 25:814-9. 2005
    ..This article gives an overview of the role of prenatal ultrasound in assessing the prognosis and discusses the post-natal surgical management and outcome...
  17. ncbi request reprint Effectiveness of alimemazine in controlling retching after Nissen fundoplication
    Brice Antao
    Department of Paediatric Surgery, Great Ormond Street Hospital, WC1N 3JH London, UK
    J Pediatr Surg 40:1737-40. 2005
    ..Alimemazine (trimeprazine, Vallergan; Castlemead, Herts, UK) is a phenothiazine derivative histamine(1) antagonist, which anecdotally relieves the retching symptoms...
  18. ncbi request reprint Oesophageal atresia: improved outcome in high-risk groups?
    Pedro Jose Lopez
    Department of Paediatric Surgery, Great Ormond Street Hospital, WC1N 3JH London, UK
    J Pediatr Surg 41:331-4. 2006
    ..Advances in neonatal care have led us to question if these outcome figures are still valid. We tested the hypothesis that the outcome of neonates with OA has improved during the last decade...
  19. ncbi request reprint Why parents of children with neurodevelopmental disabilities requiring gastrostomy feeding need more support
    Gillian M Craig
    Institute of Child Health, London, UK
    Dev Med Child Neurol 45:183-8. 2003
    ..The biomedical emphasis on health and weight-gains may fail to reflect parental concerns about tube and oral feeding. There is a need for greater practical and emotional support for families feeding children with severe disabilities...
  20. doi request reprint Bacterial counts from hospital doctors' ties are higher than those from shirts
    Pedro Jose Lopez
    Division of Surgery, Institute of Child Health, London, United Kingdom
    Am J Infect Control 37:79-80. 2009
    ..Counts were higher (P = .002) from ties that were rarely, if ever, cleaned than from shirts that were washed every 2 days or more frequently. The results support the need for further research on unwashable clothing of hospital staff...
  21. ncbi request reprint Cloacal exstrophy: morbidity associated with abnormalities of the gastrointestinal tract and spine
    Merrill McHoney
    Department of Paediatric Urology, Great Ormond Street Hospital for Children, Institute of Child Health, London, England, UK
    J Pediatr Surg 39:1209-13. 2004
    ..The aim of this study was to review the management of the gastrointestinal tract in cloacal exstrophy and to assess the effect of spinal dysraphism on nutritional outcome...
  22. ncbi request reprint Neonatal severe hyperparathyroidism: genotype/phenotype correlation and the use of pamidronate as rescue therapy
    Simon Waller
    Nephro Urology Unit, Institute of Child Health, University College of London Medical Schools and Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, WC1N 3JH London, UK
    Eur J Pediatr 163:589-94. 2004
    ..The remarkable degree of phenotypic variation demonstrated remains unexplained without functional studies; this variability highlights the challenge of treating this rare condition...
  23. ncbi request reprint Quality of life after gastric transposition for oesophageal atresia
    Lorraine Ludman
    Department of Pediatriz Surgery, Institute of Child Health, London, England
    J Pediatr Surg 38:53-7; discussion 53-7. 2003
    ..This report assesses the health-related quality of life (QOL) of 2 groups of patients born with oesophageal atresia who have undergone gastric transposition...
  24. ncbi request reprint Neonatal endotoxemia affects heart but not kidney bioenergetics
    Koji Fukumoto
    Department of Paediatric Surgery, Institute of Child Health, London, England
    J Pediatr Surg 38:690-3. 2003
    ..The aim was to determine the effects of early and late endotoxemia on neonatal cardiac and renal mitochondrial energetics...
  25. ncbi request reprint Is intralesional injection of OK-432 effective in the treatment of lymphangioma in children?
    Nigel Hall
    Department of Paediatric Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, London, UK
    Surgery 133:238-42. 2003
    ..The aim of this study was to review our experience with OK-432 injection of lymphangioma and to identify factors associated with successful outcome...
  26. ncbi request reprint Conjoined twins
    Lewis Spitz
    Department of Paediatric Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, London, England
    JAMA 289:1307-10. 2003
  27. ncbi request reprint Gastroenteric fistula complicating percutaneous endoscopic gastrostomy
    Nitin Patwardhan
    Department of Paediatric Surgery, Great Ormond Street Hospital NHS Trust, London, England, UK
    J Pediatr Surg 39:561-4. 2004
    ..Gastroenteric fistula occurs in 2% to 3% of patients undergoing percutaneous endoscopic gastrostomy (PEG). The authors identified 12 children with this major complication...
  28. ncbi request reprint The conjoined twins. Transcript of the speeches given at the BAFS annual dinner on 28 February 2002. British Academy of Forensic Sciences
    Lewis Spitz
    Med Sci Law 42:284-7. 2002
  29. ncbi request reprint Staged repair of giant omphalocele in the neonatal period
    Maurizio Pacilli
    Department of Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, WC1N 1EH London, UK
    J Pediatr Surg 40:785-8. 2005
    ..The aim of this study was to analyze the outcome of giant omphalocele repaired in the neonatal period...
  30. ncbi request reprint Bilateral anophthalmia and esophageal atresia: report of a new patient and review of the literature
    Francesco Morini
    Am J Med Genet A 132:60-2. 2005
  31. ncbi request reprint Management of pyopagus conjoined twins
    Anthony D Hockley
    Department of Neurosurgery, Birmingham Children s Hospital, B4 6NH, Birmingham, West Midlands, UK
    Childs Nerv Syst 20:635-9. 2004
    ..As the joined structures are not life-threatening, there is generally a good prognosis, with time for investigation and planning of operative separation...
  32. ncbi request reprint Gastric transposition in children--a 21-year experience
    Lewis Spitz
    Great Ormond Street Hospital for Children, London England, UK
    J Pediatr Surg 39:276-81; discussion 276-81. 2004
    ..The purpose of this study was to analyze the outcome in 173 children (104 M, 69 F) undergoing transposition since 1981...
  33. ncbi request reprint Gastrostomy feeding in infants and children on peritoneal dialysis
    Sarah E Ledermann
    Renal Unit, Great Ormond Street Hospital for Children NHS Trust, London WC1N 3JH, UK
    Pediatr Nephrol 17:246-50. 2002
    ..We recommend placement of a PEG or OG if an anti-reflux procedure is necessary prior to starting PD. Placement of a PEG while on PD is contraindicated, but an OG is a safe alternative procedure...
  34. ncbi request reprint Dorsoventral patterning in oesophageal atresia with tracheo-oesophageal fistula: Evidence from a new mouse model
    Adonis S Ioannides
    London, England
    J Pediatr Surg 37:185-91. 2002
    ..1 (Ttf 1), lead to OA/TOF. The authors aimed to integrate the 2 systems by adapting the Adriamycin model to the mouse to study molecular aspects of tracheo-oesophageal development...
  35. ncbi request reprint Decline in surgical training
    Lewis Spitz
    Lancet 359:83. 2002