Affiliation: University College London
- Peter Paul RickhamLewis Spitz
Paediatric Surgery, Hospital for Children, Great Ormond Street, WC1N3JH, London, United Kingdom
Pediatr Surg Int 19:753-4. 2004
- Esophageal atresia. Lessons I have learned in a 40-year experienceLewis Spitz
Institute of Child Health, University College, London Great Ormond Street Hospital for Children NHS Trust, London WC1 N3JH, UK
J Pediatr Surg 41:1635-40. 2006..The incidence and treatment of early and late complications is discussed...
- Oesophageal atresiaLewis Spitz
Department of Paediatric Surgery, Institute of Child Health, University College, London, UK
Orphanet J Rare Dis 2:24. 2007..Infants weighing over 1500 g and having no major cardiac problem should have a near 100% survival, while the presence of one of the risk factors reduces survival to 80% and further to 30-50% in the presence of both risk factors...
- Factors predicting failure of redo Nissen fundoplication in childrenMaurizio Pacilli
Institute of Child Health and Great Ormond Street Hospital for Children, University College London, London, UK
Pediatr Surg Int 23:499-503. 2007..Redo Nissen fundoplication has a high failure rate. Risk factors are open fundoplication at first operation and neurological impairment. Redo fundoplication after primary laparoscopic Nissen has a lower risk of failure...
- Surgical outcomes of esophageal atresia without fistula for 24 years at a single institutionAndrew J A Holland
Department of Pediatric Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, University College London, London, UK
J Pediatr Surg 44:1928-32. 2009..The aim of the study was to evaluate the surgical outcome of esophageal atresia (EA) without fistula for 24 years at a single tertiary center for pediatric surgery...
- Duhamel pull-through for Hirschsprung disease: a comparison of open and laparoscopic techniquesShireen A Nah
Department of General Surgery, Great Ormond Street Hospital and UCL Institute of Child Health, London, UK
J Pediatr Surg 47:308-12. 2012..Various pull-through techniques, both open and laparoscopic, have been performed for Hirschsprung disease. Our study compares open and laparoscopic Duhamel pull-through...
- Cardiac and renal mitochondria respond differently to hydrogen peroxide in suckling ratsKoji Fukumoto
Department of Paediatric Surgery, Institute of Child Health, London WC1N 1EH, UK
J Surg Res 113:146-50. 2003..This decrease in ATP generation may be a factor in the dysfunction of these organs during sepsis...
- Tyrosine nitration of carnitine palmitoyl transferase I during endotoxaemia in suckling ratsKoji Fukumoto
Department of Paediatric Surgery, Institute of Child Health, 30, Guilford Street, London WC1N 1EH, UK
Biochim Biophys Acta 1683:1-6. 2004..5 M dithionite, during immunoprecipitation, greatly decreased immunopositivity for M- and L-CPTI on WB. M-CPTI appears to be a novel target for peroxynitrite during endotoxaemia, which would alter myocardial substrate selection...
- Information on the World Wide Web--how useful is it for parents?Nurain Z Sim
Department of Paediatric Surgery, Great Ormond Street Hospital, London WC1N 3JH, UK
J Pediatr Surg 42:305-12. 2007..An enormous amount of information about pediatric surgical conditions is available on the World Wide Web (www). Our aim was to ascertain how many parents accessed the www and how useful they found the exercise...
- Imaging of conjoined twinsKieran McHugh
Department of Radiology, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK
Pediatr Radiol 36:899-910; quiz 1002-3. 2006..Planning of postnatal surgical separation is aided by accurate preoperative imaging which, depending on the conjoined area, will encompass many imaging modalities, but often relies heavily on CT scanning...
- Surgery for conjoined twinsLewis Spitz
Department of Paediatric Surgery, Institute of Child Health, and Great Ormond Street Children's Hospital, London, UK
Ann R Coll Surg Engl 85:230-5. 2003
- A historical vignette: gastroschisisLewis Spitz
Pediatric Surgery, Institute of Child Health and Great Ormond Street Hospital, London
J Pediatr Surg 43:1396-7. 2008..Among this collection is a fetus demonstrating a gastroschisis anomaly that had gone unrecognized for almost 200 years...
- Surgery of persistent hyperinsulinaemic hypoglycaemiaKeith J Lindley
The Institute of Child Health, University College London, London, UK
Semin Neonatol 8:259-65. 2003..Di-HI is only managed by surgery if combination drug therapies are unable to prevent hypoglycaemia. Pancreatic beta-cell dysfunction persists following subtotal pancreatectomy of di-HI...
- Moderate hypothermia protects against systemic oxidative stress in a rat model of intestinal ischemia and reperfusion injuryGiorgio Stefanutti
Department of Paediatric Surgery, Institute of Child Health, London WC1N 1EH, United Kingdom
Shock 24:159-64. 2005..However, whether these effects persist after rewarming is unknown...
- Gastric transposition in childrenLewis Spitz
Department of Paediatric Surgery, Institute of Child Health, University College London, London, United Kingdom
Semin Pediatr Surg 18:30-3. 2009..To analyze the outcome in 192 children (116 males, 76 females) undergoing transposition since 1981...
- Conjoined twinsLewis Spitz
Institute of Child Health and Great Ormond Street Hospital, London, UK
Prenat Diagn 25:814-9. 2005..This article gives an overview of the role of prenatal ultrasound in assessing the prognosis and discusses the post-natal surgical management and outcome...
- Effectiveness of alimemazine in controlling retching after Nissen fundoplicationBrice Antao
Department of Paediatric Surgery, Great Ormond Street Hospital, WC1N 3JH London, UK
J Pediatr Surg 40:1737-40. 2005..Alimemazine (trimeprazine, Vallergan; Castlemead, Herts, UK) is a phenothiazine derivative histamine(1) antagonist, which anecdotally relieves the retching symptoms...
- Oesophageal atresia: improved outcome in high-risk groups?Pedro Jose Lopez
Department of Paediatric Surgery, Great Ormond Street Hospital, WC1N 3JH London, UK
J Pediatr Surg 41:331-4. 2006..Advances in neonatal care have led us to question if these outcome figures are still valid. We tested the hypothesis that the outcome of neonates with OA has improved during the last decade...
- Why parents of children with neurodevelopmental disabilities requiring gastrostomy feeding need more supportGillian M Craig
Institute of Child Health, London, UK
Dev Med Child Neurol 45:183-8. 2003..The biomedical emphasis on health and weight-gains may fail to reflect parental concerns about tube and oral feeding. There is a need for greater practical and emotional support for families feeding children with severe disabilities...
- Bacterial counts from hospital doctors' ties are higher than those from shirtsPedro Jose Lopez
Division of Surgery, Institute of Child Health, London, United Kingdom
Am J Infect Control 37:79-80. 2009..Counts were higher (P = .002) from ties that were rarely, if ever, cleaned than from shirts that were washed every 2 days or more frequently. The results support the need for further research on unwashable clothing of hospital staff...
- Cloacal exstrophy: morbidity associated with abnormalities of the gastrointestinal tract and spineMerrill McHoney
Department of Paediatric Urology, Great Ormond Street Hospital for Children, Institute of Child Health, London, England, UK
J Pediatr Surg 39:1209-13. 2004..Nutritional supplementation is more frequently required in patients with an ileostomy. Stoma complications were higher in those with a colostomy. Morbidity is high in patients with spinal dysraphism...
- Neonatal severe hyperparathyroidism: genotype/phenotype correlation and the use of pamidronate as rescue therapySimon Waller
Nephro-Urology Unit, Institute of Child Health, University College of London Medical Schools and Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, WC1N 3JH London, UK
Eur J Pediatr 163:589-94. 2004..The remarkable degree of phenotypic variation demonstrated remains unexplained without functional studies; this variability highlights the challenge of treating this rare condition...
- Quality of life after gastric transposition for oesophageal atresiaLorraine Ludman
Department of Pediatriz Surgery, Institute of Child Health, London, England
J Pediatr Surg 38:53-7; discussion 53-7. 2003....
- Neonatal endotoxemia affects heart but not kidney bioenergeticsKoji Fukumoto
Department of Paediatric Surgery, Institute of Child Health, London, England
J Pediatr Surg 38:690-3. 2003..CONCLUSIONS: The respiratory chain is affected late in endotoxemia. Neither early nor late endotoxemia affects oxidative function of kidney mitochondria...
- Is intralesional injection of OK-432 effective in the treatment of lymphangioma in children?Nigel Hall
Department of Paediatric Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, London, UK
Surgery 133:238-42. 2003..The aim of this study was to review our experience with OK-432 injection of lymphangioma and to identify factors associated with successful outcome...
- Conjoined twinsLewis Spitz
Department of Paediatric Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, London, England
JAMA 289:1307-10. 2003
- Gastroenteric fistula complicating percutaneous endoscopic gastrostomyNitin Patwardhan
Department of Paediatric Surgery, Great Ormond Street Hospital NHS Trust, London, England, UK
J Pediatr Surg 39:561-4. 2004..CONCLUSIONS: Patients with gastroenteric fistula as a complication of PEG insertion can remain asymptomatic for prolonged periods. It often is difficult to make the diagnosis. A plain abdominal x-ray is a useful diagnostic modality...
- The conjoined twins. Transcript of the speeches given at the BAFS annual dinner on 28 February 2002. British Academy of Forensic SciencesLewis Spitz
Med Sci Law 42:284-7. 2002
- Staged repair of giant omphalocele in the neonatal periodMaurizio Pacilli
Department of Surgery, Institute of Child Health and Great Ormond Street Hospital for Children, WC1N 1EH London, UK
J Pediatr Surg 40:785-8. 2005..CONCLUSIONS: Giant omphalocele can be safely repaired in the neonatal period without opening the amniotic sac. Intestinal malrotation should be excluded and Ladd's procedure can be performed laparoscopically at a later stage...
- Bilateral anophthalmia and esophageal atresia: report of a new patient and review of the literatureFrancesco Morini
Am J Med Genet A 132:60-2. 2005
- Management of pyopagus conjoined twinsAnthony D Hockley
Department of Neurosurgery, Birmingham Children s Hospital, B4 6NH, Birmingham, West Midlands, UK
Childs Nerv Syst 20:635-9. 2004..As the joined structures are not life-threatening, there is generally a good prognosis, with time for investigation and planning of operative separation...
- Gastric transposition in children--a 21-year experienceLewis Spitz
Great Ormond Street Hospital for Children, London England, UK
J Pediatr Surg 39:276-81; discussion 276-81. 2004..A total of 19.6% of the patients needed anastomotic dilatation for stricture. In the long term, good function has been maintained. Gastric transposition compares favorably with alternative methods of esophageal replacement...
- Gastrostomy feeding in infants and children on peritoneal dialysisSarah E Ledermann
Renal Unit, Great Ormond Street Hospital for Children NHS Trust, London WC1N 3JH, UK
Pediatr Nephrol 17:246-50. 2002..We recommend placement of a PEG or OG if an anti-reflux procedure is necessary prior to starting PD. Placement of a PEG while on PD is contraindicated, but an OG is a safe alternative procedure...
- Dorsoventral patterning in oesophageal atresia with tracheo-oesophageal fistula: Evidence from a new mouse modelAdonis S Ioannides
J Pediatr Surg 37:185-91. 2002..1 (Ttf 1), lead to OA/TOF. The authors aimed to integrate the 2 systems by adapting the Adriamycin model to the mouse to study molecular aspects of tracheo-oesophageal development...
- Decline in surgical trainingLewis Spitz
Lancet 359:83. 2002