David J Spiegelhalter

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Mortality and volume of cases in paediatric cardiac surgery: retrospective study based on routinely collected data
    David J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR
    BMJ 324:261-3. 2002
  2. pmc The ProActive trial protocol - a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766]
    Kate Williams
    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, Forvie Site, Robinson Way, Cambridge CB2 2SR, UK
    BMC Public Health 4:48. 2004
  3. pmc Problems in assessing rates of infection with methicillin resistant Staphylococcus aureus
    David J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR
    BMJ 331:1013-5. 2005
  4. ncbi request reprint Funnel plots for comparing institutional performance
    David J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR, UK
    Stat Med 24:1185-202. 2005
  5. pmc Handling over-dispersion of performance indicators
    D J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR, UK
    Qual Saf Health Care 14:347-51. 2005
  6. doi request reprint Accounting for regression-to-the-mean in tests for recent changes in institutional performance: analysis and power
    Hayley E Jones
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, U K
    Stat Med 28:1645-67. 2009
  7. ncbi request reprint Being sceptical about meta-analyses: a Bayesian perspective on magnesium trials in myocardial infarction
    Julian P T Higgins
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
    Int J Epidemiol 31:96-104. 2002
  8. doi request reprint Use of the false discovery rate when comparing multiple health care providers
    Hayley E Jones
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK
    J Clin Epidemiol 61:232-240. 2008
  9. ncbi request reprint Prior distributions for the intracluster correlation coefficient, based on multiple previous estimates, and their application in cluster randomized trials
    Rebecca M Turner
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
    Clin Trials 2:108-18. 2005
  10. ncbi request reprint Bayesian approaches to multiple sources of evidence and uncertainty in complex cost-effectiveness modelling
    David J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK
    Stat Med 22:3687-709. 2003

Collaborators

Detail Information

Publications14

  1. pmc Mortality and volume of cases in paediatric cardiac surgery: retrospective study based on routinely collected data
    David J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR
    BMJ 324:261-3. 2002
    ....
  2. pmc The ProActive trial protocol - a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766]
    Kate Williams
    General Practice and Primary Care Research Unit, Department of Public Health and Primary Care, Institute of Public Health, Forvie Site, Robinson Way, Cambridge CB2 2SR, UK
    BMC Public Health 4:48. 2004
    ..While previous evaluations of interventions to increase physical activity have involved communities or individuals with established disease, less attention has been given to interventions for individuals at risk of disease...
  3. pmc Problems in assessing rates of infection with methicillin resistant Staphylococcus aureus
    David J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR
    BMJ 331:1013-5. 2005
  4. ncbi request reprint Funnel plots for comparing institutional performance
    David J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR, UK
    Stat Med 24:1185-202. 2005
    ..We conclude that funnel plots are flexible, attractively simple, and avoid spurious ranking of institutions into 'league tables'...
  5. pmc Handling over-dispersion of performance indicators
    D J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR, UK
    Qual Saf Health Care 14:347-51. 2005
    ..A number of options for handling this phenomenon are investigated, ranging from improved risk stratification to fitting a statistical model that robustly estimates the degree of over-dispersion...
  6. doi request reprint Accounting for regression-to-the-mean in tests for recent changes in institutional performance: analysis and power
    Hayley E Jones
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, U K
    Stat Med 28:1645-67. 2009
    ..Further, the power of the corrected test depends on the provider's baseline rate and, although large gains can be expected for some providers, this is at the cost of some power to detect real changes in others...
  7. ncbi request reprint Being sceptical about meta-analyses: a Bayesian perspective on magnesium trials in myocardial infarction
    Julian P T Higgins
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
    Int J Epidemiol 31:96-104. 2002
    ....
  8. doi request reprint Use of the false discovery rate when comparing multiple health care providers
    Hayley E Jones
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK
    J Clin Epidemiol 61:232-240. 2008
    ..The purpose of this article is to demonstrate a suitable alternative thresholding procedure that is already well established in other fields...
  9. ncbi request reprint Prior distributions for the intracluster correlation coefficient, based on multiple previous estimates, and their application in cluster randomized trials
    Rebecca M Turner
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
    Clin Trials 2:108-18. 2005
    ..The methods proposed enable available ICC information to be summarised appropriately by an informative prior distribution, which is of direct practical use in cluster randomized trials...
  10. ncbi request reprint Bayesian approaches to multiple sources of evidence and uncertainty in complex cost-effectiveness modelling
    David J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK
    Stat Med 22:3687-709. 2003
    ..All computations are carried out using freely available software for conducting Markov chain Monte Carlo analysis...
  11. ncbi request reprint Reported use of data monitoring committees in the main published reports of randomized controlled trials: a cross-sectional study
    Matthew R Sydes
    MRC Clinical Trials Unit, 222 Euston Road, London NW1 2DA, UK
    Clin Trials 1:48-59. 2004
    ..We describe a review of published main reports of randomized controlled trials (RCTs), in order to measure the frequency of reported use of data monitoring committees (DMCs) and factors associated with reported DMC use...
  12. ncbi request reprint Systematic qualitative review of the literature on data monitoring committees for randomized controlled trials
    Matthew R Sydes
    MRC Clinical Trials Unit, 222 Euston Rd, London NW1 2DA, UK
    Clin Trials 1:60-79. 2004
    ..To systematically review the published literature on data monitoring committees (DMCs) for randomized controlled trials (RCT) and summarize information and opinions on best practice. This was part of the DAMOCLES project...
  13. ncbi request reprint Flexible design and efficient implementation of adaptive dose-finding studies
    Christopher J Weir
    Robertson Centre for Biostatistics, University of Glasgow, University Avenue, Glasgow, UK
    J Biopharm Stat 17:1033-50. 2007
    ..We identify appropriate settings for this algorithm and illustrate its application in the context of a normal dynamic linear model used in a dose-finding clinical trial of a neutrophil inhibitory factor in acute ischaemic stroke...
  14. pmc Understanding uncertainty
    David J Spiegelhalter
    Ann Fam Med 6:196-7. 2008