Research Topics
Genomes and Genes
Species | Edmund J S Sonuga-BarkeSummaryAffiliation: University of Southampton Country: UK Publications
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Publications
The dual pathway model of AD/HD: an elaboration of neuro-developmental characteristicsEdmund J S Sonuga-Barke
Department of Psychology, Centre for the Study of Psychological Development, University of Southampton, Southampton S017 1BJ, UK
Neurosci Biobehav Rev 27:593-604. 2003..In the current paper we describe the development of this model in more detail. We elaborate on the neuro-circuitry possibly underpinning these two pathways and explore their developmental significance within a neuro-ecological framework...
Nonpharmacological interventions for ADHD: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatmentsEdmund J S Sonuga-Barke
Developmental Brain Behaviour Laboratory, Department of Psychology, University of Southampton, UK
Am J Psychiatry 170:275-89. 2013....
Neuroeconomics of attention-deficit/hyperactivity disorder: differential influences of medial, dorsal, and ventral prefrontal brain networks on suboptimal decision making?Edmund J S Sonuga-Barke
Institute for Disorders of Impulse and Attention, School of Psychology, University of Southampton, Southampton, United Kingdom
Biol Psychiatry 72:126-33. 2012..Finally, we extend this perspective to consider three contemporary themes in ADHD research...
Eunethydis: a statement of the ethical principles governing the relationship between the European group for ADHD guidelines, and its members, with commercial for-profit organisationsJoseph A Sergeant
Clinical Neuropsychology, Vrije Universiteit, Amsterdam, The Netherlands
Eur Child Adolesc Psychiatry 19:737-9. 2010....
Distinguishing low frequency oscillations within the 1/f spectral behaviour of electromagnetic brain signalsCharmaine Demanuele
Signal Processing and Control Group, Institute of Sound and Vibration Research, University of Southampton, Southampton, UK
Behav Brain Funct 3:62. 2007..abstract:..
The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysisRobert D Oades
Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Essen, Germany
Behav Brain Funct 4:48. 2008..abstract:..
The effects of background white noise on memory performance in inattentive school childrenGöran B W Söderlund
Department of Linguistics, Stockholm University, Sweden
Behav Brain Funct 6:55. 2010..On the basis of this model we predicted that inattentive children would be enhanced by adding background white noise while attentive children's performance would deteriorate...
Does the cortisol response to stress mediate the link between expressed emotion and oppositional behavior in Attention-Deficit/Hyperactivity-Disorder (ADHD)?Hanna Christiansen
Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg Essen, Germany
Behav Brain Funct 6:45. 2010..EE has been linked to altered stress responses in some disorders, but ADHD has not been studied. We test the hypothesis that OPB in ADHD is mediated by altered stress-related cortisol reactivity to EE...
The impact of study design and diagnostic approach in a large multi-centre ADHD study: Part 2: Dimensional measures of psychopathology and intelligenceUeli C Muller
Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland
BMC Psychiatry 11:55. 2011..In particular, to investigate the influence of age, gender, family status (proband vs. sibling), informant, and centres on sample homogeneity in psychopathological measures...
The impact of study design and diagnostic approach in a large multi-centre ADHD study. Part 1: ADHD symptom patternsUeli C Muller
Department of Child and Adolescent Psychiatry, University of Zurich, Switzerland
BMC Psychiatry 11:54. 2011..A particular focus was on the effects of the study design and the diagnostic procedure on the homogeneity of the sample in terms of symptom-based behavioural data, and potential consequences for further analyses based on these data...
Dopamine transporter 3'UTR VNTR genotype is a marker of performance on executive function tasks in children with ADHDSherif Karama
Department of Psychiatry, McGill University, Montreal, Canada
BMC Psychiatry 8:45. 2008..Executive function deficits are considered among the most important pathogenic pathways leading to ADHD and may index part of the heterogeneity in this disorder...
Intelligence in DSM-IV combined type attention-deficit/hyperactivity disorder is not predicted by either dopamine receptor/transporter genes or other previously identified risk alleles for attention-deficit/hyperactivity disorderEdmund J S Sonuga-Barke
School of Psychology, University of Southampton, Southampton, UK
Am J Med Genet B Neuropsychiatr Genet 147:316-9. 2008..We also observed no association of other SNPs with IQ in ADHD...
Adverse reactions to methylphenidate treatment for attention-deficit/hyperactivity disorder: structure and associations with clinical characteristics and symptom controlEdmund J S Sonuga-Barke
Institute for Disorders of Impulse and Attention, School of Psychology, University of Southampton, UK
J Child Adolesc Psychopharmacol 19:683-90. 2009..Methylphenidate (MPH)-related adverse events are well characterized. Their predictors and their relationship with therapeutic effects are less well understood. Here we examine these issues in relation to two long-acting formulations...
Context-dependent dynamic processes in attention deficit/hyperactivity disorder: differentiating common and unique effects of state regulation deficits and delay aversionEdmund J S Sonuga-Barke
Institute for Disorders of Impulse and Attention, School of Psychology, University of Southampton, Southampton, UK
Neuropsychol Rev 20:86-102. 2010..Finally, we highlight the implications of neuropsychological heterogeneity for the practical implementation of tests of DAv and SRD...
Heterogeneity in the pharmacodynamics of two long-acting methylphenidate formulations for children with attention deficit/hyperactivity disorder. A growth mixture modelling analysisEdmund J S Sonuga-Barke
School of Psychology, Institute for Disorders of Impulse and Attention, University of Southampton, Southampton, UK
Eur Child Adolesc Psychiatry 17:245-54. 2008....
Dopamine and serotonin transporter genotypes moderate sensitivity to maternal expressed emotion: the case of conduct and emotional problems in attention deficit/hyperactivity disorderEdmund J S Sonuga-Barke
Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, Southampton, UK
J Child Psychol Psychiatry 50:1052-63. 2009....
Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scanEdmund J S Sonuga-Barke
Developmental Brain Behaviour Unit, University of Southampton, Southampton, UK
Am J Med Genet B Neuropsychiatr Genet 147:1359-68. 2008..We find evidence for the role of EE in moderating the effects of genes on ADHD severity and comorbid conduct disorder, implicating both novel and established candidates. These findings need replicating in larger independent samples...
Inattentive/overactive children with histories of profound institutional deprivation compared with standard ADHD cases: a brief reportE J S Sonuga-Barke
Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, Southampton, UK
Child Care Health Dev 34:596-602. 2008..The Inattention/Overactivity/Impulsiveness (I/OA) behavioural cluster diagnostic of ADHD is recognized as a characteristic outcome of early institutional care...
Is sub-nutrition necessary for a poor outcome following early institutional deprivation?Edmund J S Sonuga-Barke
Social, Genetic, Developmental Psychiatry Centre, Institute of Psychiatry, Kings College, University of London, London, UK
Dev Med Child Neurol 50:664-71. 2008..Further studies of functional and structural neuroanatomy following institutional deprivation are required to delineate the role of brain development in its effects...
Sex differences in the response of children with ADHD to once-daily formulations of methylphenidateEdmund J S Sonuga-Barke
Developmental Brain Behaviour Unit, University of Southampton, Southampton, UK
J Am Acad Child Adolesc Psychiatry 46:701-10. 2007..This paper reports an examination of sex differences based on further analysis of data from a comparison of two once-daily methylphenidate formulations (the COMACS study), which addresses these shortcomings...
Executive dysfunction and delay aversion in attention deficit hyperactivity disorder: nosologic and diagnostic implicationsEdmund J S Sonuga-Barke
School of Psychology, Institute for Disorder on Impulse and Attention, University of Southampton, Highfield, Southampton SO17 1BJ, UK
Child Adolesc Psychiatr Clin N Am 17:367-84, ix. 2008....
Spontaneous attentional fluctuations in impaired states and pathological conditions: a neurobiological hypothesisEdmund J S Sonuga-Barke
Developmental Brain and Behaviour Unit, School of Psychology, University of Southampton, Southampton, UK
Neurosci Biobehav Rev 31:977-86. 2007..Finally, we explore the putative role of default-mode interference as a cause of performance variability in attention deficit/hyperactivity disorder...
Measuring methylphenidate response in attention-deficit/hyperactvity disorder: how are laboratory classroom-based measures related to parent ratings?Edmund J S Sonuga-Barke
Institute for Disorders of Impulse and Attention, School of Psychology, University of Southampton, UK
J Child Adolesc Psychopharmacol 19:691-8. 2009..Here we examine the associations between ratings and one such method, assessments made across the day in the laboratory classroom...
Causal models of attention-deficit/hyperactivity disorder: from common simple deficits to multiple developmental pathwaysEdmund J S Sonuga-Barke
Developmental Brain Behaviour Unit, School of Psychology, University of Southampton, Southampton, United Kingdom
Biol Psychiatry 57:1231-8. 2005..The possibility of neuropathologic heterogeneity in ADHD is likely to have important implications for the clinical management of the condition, potentially impacting on both diagnostic strategies and treatment options...
Are planning, working memory, and inhibition associated with individual differences in preschool ADHD symptoms?Edmund J S Sonuga-Barke
Centre for Research into Psychological Development, Department of Psychology, University of Southampton, England
Dev Neuropsychol 21:255-72. 2002..This association provides evidence for Barkley's (1997) view that ADHD is underpinned by inhibitory deficits in the preschool period...
Do executive deficits and delay aversion make independent contributions to preschool attention-deficit/hyperactivity disorder symptoms?Edmund J S Sonuga-Barke
School of Psychology, University of Southampton, Southampton SO17 1BJ, UK
J Am Acad Child Adolesc Psychiatry 42:1335-42. 2003..To test whether deficits in executive function and delay aversion make independent contributions to levels of attention-deficit/hyperactivity disorder (ADHD) symptoms exhibited by preschool children...
AD/HD and the capture of attention by briefly exposed delay-related cues: evidence from a conditioning paradigmEdmund J S Sonuga-Barke
Centre for Research into Psychological Development, Department of Psychology, University of Southampton, Highfield, UK
J Child Psychol Psychiatry 45:274-83. 2004..The selective attention of children with attention deficit/hyperactivity disorder (AD/HD) to briefly exposed delay-related cues was examined in two experiments using a dot-probe conditioning paradigm...
Early detection and intervention for attention-deficit/hyperactivity disorderEdmund J S Sonuga-Barke
Institute for Disorder of Impulse and Attention, School of Psychology, University of Southampton, Southampton, SO17 1BJ, UK
Expert Rev Neurother 11:557-63. 2011....
Psychological heterogeneity in AD/HD--a dual pathway model of behaviour and cognitionEdmund J S Sonuga-Barke
Centre for Research into Psychological Development, Department of Psychology, University of Southampton, SO17 1BJ, UK
Behav Brain Res 130:29-36. 2002..g. nucleus accumbens). The two pathways are further distinguished at the levels of symptoms, cognitive and motivation profiles and genetic and non-genetic origins...
A functional variant of the serotonin transporter gene (SLC6A4) moderates impulsive choice in attention-deficit/hyperactivity disorder boys and siblingsEdmund J S Sonuga-Barke
Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, Southampton, United Kingdom
Biol Psychiatry 70:230-6. 2011..We hypothesized that IDIR would be associated with dopamine regulating genes and delay aversion would be associated with serotonin-regulating genes...
Efficacy of two once-daily methylphenidate formulations compared across dose levels at different times of the day: preliminary indications from a secondary analysis of the COMACS study dataEdmund J S Sonuga-Barke
The Developmental Brain Behaviour Unit, University of Southampton, Southampton, SO17 1BJ UK
BMC Psychiatry 4:28. 2004..The current paper presents a secondary analysis that provides a statistical test of these observations...
Parent training for Attention Deficit/Hyperactivity Disorder: is it as effective when delivered as routine rather than as specialist care?Edmund J S Sonuga-Barke
Developmental Brain Behaviour Unit, School of Psychology, University of Southampton, UK
Br J Clin Psychol 43:449-57. 2004..The effectiveness of parent training (PT) when delivered as part of specialist tier-two services for preschool AD/HD children has been recently demonstrated...
The neuroscience of ADHD: multidisciplinary perspectives on a complex developmental disorderEdmund J S Sonuga-Barke
Developmental Brain and Behaviour Unit, School of Psychology, University of Southampton, SO17 1BJ, UK
Dev Sci 8:103-4. 2005
Beyond the dual pathway model: evidence for the dissociation of timing, inhibitory, and delay-related impairments in attention-deficit/hyperactivity disorderEdmund Sonuga-Barke
Institute for Disorder of Impulse and Attention, School of Psychology, University of Southampton, Highfield, Southampton SO17 1BJ, UK
J Am Acad Child Adolesc Psychiatry 49:345-55. 2010..We explore whether deficits in temporal processing might constitute a third dissociable neuropsychological component of ADHD...
Varieties of preschool hyperactivity: multiple pathways from risk to disorderEdmund J S Sonuga-Barke
School of Psychology, University of Southampton, Southampton, SO17 1BJ, UK
Dev Sci 8:141-50. 2005..An illustrative taxonomy of four developmental pathways implicating preschool hyperactivity is presented to provide a framework for future research...
Scholastic attainment following severe early institutional deprivation: a study of children adopted from RomaniaCelia Beckett
MRC SGDP Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
J Abnorm Child Psychol 35:1063-73. 2007..When these factors were taken into account, only small between-group differences in attainment remained...
Do theory of mind and executive function deficits underlie the adverse outcomes associated with profound early deprivation?: findings from the English and Romanian adoptees studyEmma Colvert
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College, London, UK
J Abnorm Child Psychol 36:1057-68. 2008....
Emotional difficulties in early adolescence following severe early deprivation: findings from the English and Romanian adoptees studyEmma Colvert
Institute of Psychiatry, King s College, University of London, Denmark Hill, London, SE58AF UK
Dev Psychopathol 20:547-67. 2008..There was some evidence that emotion recognition might play a role in the emergence of these problems, but other measures of social competence and theory of mind showed no associations with the onset of emotional problems...
Early adolescent outcomes of institutionally-deprived and non-deprived adoptees. II: language as a protective factor and a vulnerable outcomeCarla Croft
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Kings College London, UK
J Child Psychol Psychiatry 48:31-44. 2007..There is uncertainty about the extent to which language skills are part of general intelligence and even more uncertainty on whether deprivation has differential effects on language and non-language skills...
Inattention/overactivity following early severe institutional deprivation: presentation and associations in early adolescenceSuzanne E Stevens
Developmental Brain Behaviour Unit, School of Psychology, University of Southampton, Southampton, UK
J Abnorm Child Psychol 36:385-98. 2008....
Electrophysiological markers of the motivational salience of delay imposition and escapeSamantha J Broyd
Institute for Disorders of Impulse and Attention, Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, UK
Neuropsychologia 50:965-72. 2012....
Normality and impairment following profound early institutional deprivation: a longitudinal follow-up into early adolescenceJana M Kreppner
Social, Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, King s College London, London, England
Dev Psychol 43:931-46. 2007..The findings are discussed in terms of the possibility of a sensitive period for development...
Mothers' expressed emotion toward their school-aged sons. Associations with child and maternal symptoms of psychopathologyLamprini Psychogiou
School of Psychology, University of Southampton, Highfield, Southampton, UK
Eur Child Adolesc Psychiatry 16:458-64. 2007..However the association with specific types of behaviour problems and the influence of both child and adult psychopathology on these relationships require further clarification...
An electrophysiological monetary incentive delay (e-MID) task: a way to decompose the different components of neural response to positive and negative monetary reinforcementSamantha J Broyd
Institute for Disorders of Impulse and Attention, Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, UK
J Neurosci Methods 209:40-9. 2012....
Delay Aversion in Attention Deficit/Hyperactivity Disorder: an empirical investigation of the broader phenotypeParaskevi Bitsakou
Developmental Brain Behaviour Laboratory, University of Southampton, UK
Neuropsychologia 47:446-56. 2009....
Altered spontaneous low frequency brain activity in attention deficit/hyperactivity disorderSuzannah K Helps
Institute for Disorders for Impulse and Attention, Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, UK
Brain Res 1322:134-43. 2010..ADHD children may have deficits both in maintaining a resting brain when needed and 'protecting' an active brain from the intrusion of resting state brain activity...
A small-scale randomized controlled trial of the revised new forest parenting programme for preschoolers with attention deficit hyperactivity disorderMargaret J J Thompson
School of Psychology, Institute for Disorders of Impulse and Attention, University of Southampton, Southampton SO17 1BJ, UK
Eur Child Adolesc Psychiatry 18:605-16. 2009..The small-scale trial, although limited in power and generalizability, provides support for the efficacy of the revised NFPP. The findings need to be replicated in a larger more diverse sample...
Disentangling child and family influences on maternal expressed emotion toward children with attention-deficit/hyperactivity disorderKim L Cartwright
Institute for Disorders of Impulse and Attention, School of Psychology, University of Southampton, UK
J Am Acad Child Adolesc Psychiatry 50:1042-53. 2011....
The adolescent outcome of hyperactive girls: self-report of psychosocial statusSusan Young
Department of Psychology, Institute of Psychiatry, London, UK
J Child Psychol Psychiatry 46:255-62. 2005..The aim of the study was to clarify the developmental risk associated with hyperactive behaviour in girls in a longitudinal epidemiological design...
Do maternal attention-deficit/hyperactivity disorder symptoms exacerbate or ameliorate the negative effect of child attention-deficit/hyperactivity disorder symptoms on parenting?Lamprini Psychogiou
University of Southampton, Southampton, UK
Dev Psychopathol 20:121-37. 2008..The results support the similarity-fit hypothesis and highlight the importance of considering both child and maternal ADHD symptoms in studies of parenting...
Dopamine transporter gene polymorphism moderates the effects of severe deprivation on ADHD symptoms: developmental continuities in gene-environment interplaySuzanne E Stevens
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
Am J Med Genet B Neuropsychiatr Genet 150:753-61. 2009....
Early adolescent outcomes for institutionally-deprived and non-deprived adoptees. I: disinhibited attachmentMichael Rutter
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
J Child Psychol Psychiatry 48:17-30. 2007....
Amygdala, hippocampal and corpus callosum size following severe early institutional deprivation: the English and Romanian Adoptees study pilotMitul A Mehta
Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
J Child Psychol Psychiatry 50:943-51. 2009..These pilot findings highlight the need for future studies to confirm the sensitivity of the amygdala to early deprivation...
The quick delay questionnaire: a measure of delay aversion and discounting in adultsSylvia Clare
Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, Highfield, UK
Atten Defic Hyperact Disord 2:43-8. 2010..The QDQ is a potentially valuable way of assessing response to delay in adults. Further work is required to validate the scale against direct observation and neuropsychological assessment in clinically ascertained samples...
Neuronal oscillations in the EEG under varying cognitive load: a comparative study between slow waves and faster oscillationsCharmaine Demanuele
Signal Processing and Control Group, Institute of Sound and Vibration Research, University of Southampton, UK
Clin Neurophysiol 124:247-62. 2013....
Identifying a distinctive familial frequency band in reaction time fluctuations in ADHDSuzannah K Helps
Institute for Disorders of Impulse and Attention, Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, United Kingdom
Neuropsychology 25:711-9. 2011..We also assess the familiality of these frequencies by using a proband-sibling design...
The adolescent outcome of hyperactive girls. Self-reported interpersonal relationships and coping mechanismsSusan Young
Department of Psychology, PO78, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Eur Child Adolesc Psychiatry 14:245-53. 2005..It is concluded that early therapeutic interventions targeting the development of social skills and problem-solving skills are required in order to help overcome these problems in later life...
Attention-induced deactivations in very low frequency EEG oscillations: differential localisation according to ADHD symptom statusSamantha J Broyd
Developmental Brain Behaviour Laboratory, School of Psychology, Institute for Disorders of Impulse and Attention, University of Southampton, Southampton, United Kingdom
PLoS ONE 6:e17325. 2011..Previously we have identified a VLF EEG network of scalp locations that shares many features of the DMN. Here we explore the intracranial sources of VLF EEG and examine their overlap with the DMN in adults with high and low ADHD ratings...
Inhibitory deficits, delay aversion and preschool AD/HD: implications for the dual pathway modelLindy Dalen
Developmental Brain-Behaviour Unit, Department of Psychology University of Southampton, Highfield, Southampton, England
Neural Plast 11:1-11. 2004..The data support the value of the distinction between motivational and cognitive pathways to AD/HD. Furthermore, the data suggest that such a distinction is apparent relatively early on during development...
Probing the limits of delay intolerance: preliminary young adult data from the Delay Frustration Task (DeFT)Paraskevi Bitsakou
Developmental Brain-Behaviour Unit, School of Psychology, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom
J Neurosci Methods 151:38-44. 2006..DeFT may provide a useful index of delay tolerance in young adults with ADHD. Future research needs to examine DeFT performance in different age groups and in clinical and non-clinical populations...
Parenting behaviour described by mothers in a general population sampleMargaret J J Thompson
Department of Psychiatry, University of Southampton, UK
Child Care Health Dev 28:149-55. 2002..To collect mothers' reports of the range of behaviours used by them in the management of their children's difficult behaviour...
Slow neuronal oscillations in the resting brain vs task execution: A BSS investigation of EEG recordingsCharmaine Demanuele
Signal Processing and Control Group, ISVR, University of Southampton, SO17 1BJ, UK
Conf Proc IEEE Eng Med Biol Soc 2010:1638-41. 2010..The methodology and findings presented here provide a new basis for assessing neural activity during various mental conditions...
Interval length and time-use by children with AD/HD: a comparison of four modelsEdmund J S Sonuga-Barke
Centre for Research into Psychological Development, Department of Psychology, University of Southhampton at Highfield, England
J Abnorm Child Psychol 30:257-64. 2002..This quadratic function provided support for the State Regulation Deficit model of time use in AD/HD. The value of tailoring the temporal features of learning contexts to the conceptual style of AD/HD children is discussed...
Genetic heterogeneity in ADHD: DAT1 gene only affects probands without CDKaixin Zhou
MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, United Kingdom
Am J Med Genet B Neuropsychiatr Genet 147:1481-7. 2008..Although the result needs further replications, it does highlight the importance of selecting genetically homogeneous samples for molecular genetic analyses of ADHD...
On the reorganization of incentive structure to promote delay tolerance: a therapeutic possibility for AD/HD?Edmund J S Sonuga-Barke
Developmental Brain Behavior Unit, University of Southampton, Highfield, Southampton, England SO17 1BJ
Neural Plast 11:23-8. 2004..Delay fading is proposed as a possible basis for reorganizing delay experience, altering the incentive value of delay (e.g., increasing tolerance for delay), thereby reducing AD/HD symptoms...
The attention-deficit/hyperactivity disorder medication-related attitudes of patients and their parentsRuth Ann Harpur
Institute of Disorder of Impulse and Attention, School of Psychology, University of Southampton, UK
J Child Adolesc Psychopharmacol 18:461-73. 2008..Future research should focus on the scales value in predicting treatment adherence as it impacts on medication effectiveness...
Does maternal ADHD reduce the effectiveness of parent training for preschool children's ADHD?Edmund J S Sonuga-Barke
Centre for Research into Psychological Development, Department of Psychology, University of Southampton, England
J Am Acad Child Adolesc Psychiatry 41:696-702. 2002..To assess the impact of maternal attention-deficit/hyperactivity disorder (ADHD) symptoms on the effectiveness of a parent training (PT) program for preschool ADHD...
The decisions regarding ADHD management (DRAMa) study: uncertainties and complexities in assessment, diagnosis and treatment, from the clinician's point of viewHanna Kovshoff
Developmental Brain Behaviour Laboratory, Institute for Disorders of Impulse and Attention, School of Psychology, University of Southampton, Southampton, UK
Eur Child Adolesc Psychiatry 21:87-99. 2012..Clinical guidelines would benefit from revisions to take into account the real-world complexities of clinical decision making for ADHD...
Children born small for gestational age are not at special risk for preschool emotion and behaviour problemsChristine M Cornforth
Department of Paediatrics Child and Youth Health, University of Auckland, New Zealand
Early Hum Dev 88:479-85. 2012..These results do not support the view that SGA is a risk for behavioural preschool difficulties or that SGA children are sensitised to risks known to be associated with such difficulties in the preschool years...
Annual research review: categories versus dimensions in the classification and conceptualisation of child and adolescent mental disorders--implications of recent empirical studyDavid Coghill
Division of Medical Sciences, Centre for Neuroscience, University of Dundee, Dundee Institute for Disorder of Impulse and Attention, University of Southampton, Southampton, UK
J Child Psychol Psychiatry 53:469-89. 2012..Finally, we explore the implications of these findings for clinical practice and science...
Default-mode brain dysfunction in mental disorders: a systematic reviewSamantha J Broyd
Institute for Disorders of Impulse and Attention, Developmental Brain Behaviour Laboratory, School of Psychology, University of Southampton, UK
Neurosci Biobehav Rev 33:279-96. 2009..Finally, we provide an integrative overview and highlight important challenges and tasks for future research...
Developmental phenotypes and causal pathways in attention deficit/hyperactivity disorder: potential targets for early intervention?Edmund J S Sonuga-Barke
Developmental Brain Behaviour Laboratory, University of Southampton, Southampton, SO17 1BJ, UK
J Child Psychol Psychiatry 51:368-89. 2010....
Population differences in the International Multi-Centre ADHD Gene ProjectBenjamin M Neale
MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
Genet Epidemiol 32:98-107. 2008..Any case-control sample employing an Israeli sample with Northern Europeans must consider stratification. A Northern European tag set, however, appears to be appropriate for capturing the variation across populations...
Genome-wide association scan of attention deficit hyperactivity disorderBenjamin M Neale
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
Am J Med Genet B Neuropsychiatr Genet 147:1337-44. 2008..We additionally identify a systemic bias in family-based association, and suggest that variable missing genotype rates may be the source of this bias...
Isolating N400 as neural marker of vocal anger processing in 6-11-year old childrenGeorgia Chronaki
Developmental Brain Behaviour Laboratory, Psychology, University of Southampton, UK
Dev Cogn Neurosci 2:268-76. 2012..This study represents the first attempt to isolate a neural marker of vocal anger processing in children using electrophysiological methods...
Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorderKaixin Zhou
Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
Am J Med Genet B Neuropsychiatr Genet 147:1392-8. 2008..In addition there are nine other genomic regions from the GSMA showing nominal or suggestive evidence of linkage. All these linkage results may be informative and focus the search for novel ADHD susceptibility genes...
European clinical guidelines for hyperkinetic disorder -- first upgradeEric Taylor
Dept of Child and Adolescent Psychiatry, Institute of Psychiatry Kings College London, De Crespigny Park, London, SE5 8AF, UK
Eur Child Adolesc Psychiatry 13:I7-30. 2004..The validity of clinical guidelines changes over time, because new evidence-based knowledge and experience develop...
DSM-IV combined type ADHD shows familial association with sibling trait scores: a sampling strategy for QTL linkageWai Chen
MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, United Kingdom
Am J Med Genet B Neuropsychiatr Genet 147:1450-60. 2008..In conclusion, these data confirm the main requirement for QTL mapping of ADHD by demonstrating that narrowly defined DSM-IV combined type probands show familial association with dimensional ADHD symptom scores amongst their siblings...
Confirmation that a specific haplotype of the dopamine transporter gene is associated with combined-type ADHDPhilip Asherson
MRC Social Genetic Developmental and Psychiatry Centre, Institute of Psychiatry, London, SE5 8AF UK
Am J Psychiatry 164:674-7. 2007....
Linkage to chromosome 1p36 for attention-deficit/hyperactivity disorder traits in school and home settingsKaixin Zhou
MRC Social Genetic Developmental and Psychiatry Centre, King s College London, London, UK
Biol Psychiatry 64:571-6. 2008..The International Multi-centre ADHD Genetics (IMAGE) project performed a whole genome linkage scan specifically designed to map ADHD quantitative trait loci (QTL)...
Online measurement of motivational processes: introducing the Continuous Delay Aversion Test (ConDAT)Ueli C Muller
Department of Child and Adolescent Psychiatry, University of Zurich, Neumunsterallee 9, 8032 Zurich, Switzerland
J Neurosci Methods 151:45-51. 2006..Pilot data give evidence for satisfactory reliability and external validity of the task...
Varieties of attention-deficit/hyperactivity disorder-related intra-individual variabilityF Xavier Castellanos
Institute for Pediatric Neuroscience, New York University, Child Study Center, NYU School of Medicine, New York, New York 10016, USA
Biol Psychiatry 57:1416-23. 2005..These results highlight the importance of retaining time-series data and quantitatively examining intra-subject measures of variability as a putative endophenotype for ADHD...
[Long-acting medications for the treatment of hyperkinetic disorders - a systematic review and European treatment guideline. Part 1: overview and recommendations]Tobias Banaschewski
Klinik fur Psychiatrie und Psychotherapie des Kindes und Jugendalters, Zentralinstitut fur Seelische Gesundheit, Mannheim
Z Kinder Jugendpsychiatr Psychother 36:81-94; quiz 94-5. 2008..3) Both ATX and extended-release stimulants should be available. In addition, detailed recommendations will be made with regard to the criteria to be applied in choosing a preparation for the individual patient...
[Long-acting medications for the treatment of hyperkinetic disorders - a systematic review and European treatment guidelines. Part 2: a quantitative evaluation of long-acting medications]Tobias Banaschewski
Klinik fur Psychiatrie und Psychotherapie des Kindes und Jugendalters, Zentralinstitut fur Seelische Gesundheit, Mannheim
Z Kinder Jugendpsychiatr Psychother 36:97-106; quiz 106-7. 2008..Individual choices of therapy are necessary. (3) Both ATX and retarded-release stimulants should be available...
Causal heterogeneity in attention-deficit/hyperactivity disorder: do we need neuropsychologically impaired subtypes?Joel T Nigg
Department of Psychology, Michigan State University, East Lansing, Michigan 48824, USA
Biol Psychiatry 57:1224-30. 2005....
Do the effects of early severe deprivation on cognition persist into early adolescence? Findings from the English and Romanian adoptees studyCelia Beckett
Institute of Psychiatry, King s College London
Child Dev 77:696-711. 2006..The findings draw attention to the psychological as well as physical risks of institutional deprivation...
Long-acting medications for the hyperkinetic disorders. A systematic review and European treatment guidelineTobias Banaschewski
Dept of Child and Adolescent Psychiatry Psychotherapy, University of Goettingen, Von Siebold Str 5, 37075 Goettingen, Germany
Eur Child Adolesc Psychiatry 15:476-95. 2006..Individual clinical choice is needed. (3) Both ATX and extended-release preparations of stimulants should be available. The choice will depend upon the circumstances, and detailed recommendations are made...
EditorialEdmund J S Sonuga-Barke
J Child Psychol Psychiatry 46:225-6. 2005
The application of the Conners' Rating Scales to a Sudanese sample: an analysis of parents' and teachers' ratings of childhood behaviour problemsAhmed M El-Hassan Al-Awad
Department of Education, University of Gezira, Sudan
Psychol Psychother 75:177-87. 2002..Future research should look to supplement studies using adaptations of scales developed in Western settings with more open-ended questions about problems of specific significance to Sudanese parents...
Cingulate-precuneus interactions: a new locus of dysfunction in adult attention-deficit/hyperactivity disorderF Xavier Castellanos
Phyllis Green and Randolph Cowen Institute for Pediatric Neuroscience, New York University Child Study Center, New York, NY 10016, USA
Biol Psychiatry 63:332-7. 2008....
Mother and child: reflections on developmental science in the realm of practical politicsEdmund J S Sonuga-Barke
J Child Psychol Psychiatry 49:113-4. 2008
Characterizing cognition in ADHD: beyond executive dysfunctionF Xavier Castellanos
Institute for Pediatric Neuroscience, NYU Child Study Center, 215 Lexington Avenue, New York, NY 10016, USA
Trends Cogn Sci 10:117-23. 2006..Such a reconceptualization provides a means to transcend the limits of current models of executive dysfunction in ADHD and suggests a plan for future research on cognition grounded in neurophysiological and developmental considerations...
