Stephen M Smith

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Variability in fMRI: a re-examination of inter-session differences
    Stephen M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Department of Clinical Neurology, Oxford University, John Radcliffe Hospital, Headington, Oxford, United Kingdom
    Hum Brain Mapp 24:248-57. 2005
  2. doi The future of FMRI connectivity
    Stephen M Smith
    Oxford University Centre for Functional MRI of the Brain, UK
    Neuroimage 62:1257-66. 2012
  3. ncbi Advances in functional and structural MR image analysis and implementation as FSL
    Stephen M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Department of Clinical Neurology, John Radcliffe Hospital, Oxford University, Headington, Oxford OX3 9DU, UK
    Neuroimage 23:S208-19. 2004
  4. ncbi Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data
    Stephen M Smith
    Oxford University Centre for Functional MRI of the Brain FMRIB, Dept Clinical Neurology, University of Oxford, UK
    Neuroimage 31:1487-505. 2006
  5. ncbi Acquisition and voxelwise analysis of multi-subject diffusion data with tract-based spatial statistics
    Stephen M Smith
    Oxford University Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, UK
    Nat Protoc 2:499-503. 2007
  6. pmc Functional connectomics from resting-state fMRI
    Stephen M Smith
    Oxford Centre for Functional MRI of the Brain FMRIB, University of Oxford, Oxford, UK Electronic address
    Trends Cogn Sci 17:666-82. 2013
  7. pmc Resting-state fMRI in the Human Connectome Project
    Stephen M Smith
    FMRIB Oxford Centre for Functional MRI of the Brain, Oxford University, Oxford, UK
    Neuroimage 80:144-68. 2013
  8. pmc Temporally-independent functional modes of spontaneous brain activity
    Stephen M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 109:3131-6. 2012
  9. ncbi Normalized accurate measurement of longitudinal brain change
    S M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, England
    J Comput Assist Tomogr 25:466-75. 2001
  10. ncbi Longitudinal and cross-sectional analysis of atrophy in Alzheimer's disease: cross-validation of BSI, SIENA and SIENAX
    Stephen M Smith
    Oxford University Centre for Functional MRI of the Brain FMRIB, Oxford, UK
    Neuroimage 36:1200-6. 2007

Detail Information

Publications74

  1. ncbi Variability in fMRI: a re-examination of inter-session differences
    Stephen M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Department of Clinical Neurology, Oxford University, John Radcliffe Hospital, Headington, Oxford, United Kingdom
    Hum Brain Mapp 24:248-57. 2005
    ..Finally, we show that the use of different first-level preprocessing, time-series statistics, and registration analysis methodologies can give significantly different inter-session analysis results...
  2. doi The future of FMRI connectivity
    Stephen M Smith
    Oxford University Centre for Functional MRI of the Brain, UK
    Neuroimage 62:1257-66. 2012
    ....
  3. ncbi Advances in functional and structural MR image analysis and implementation as FSL
    Stephen M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Department of Clinical Neurology, John Radcliffe Hospital, Oxford University, Headington, Oxford OX3 9DU, UK
    Neuroimage 23:S208-19. 2004
    ..The majority of the research laid out in this paper has been implemented as freely available software tools within FMRIB's Software Library (FSL)...
  4. ncbi Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data
    Stephen M Smith
    Oxford University Centre for Functional MRI of the Brain FMRIB, Dept Clinical Neurology, University of Oxford, UK
    Neuroimage 31:1487-505. 2006
    ..TBSS aims to improve the sensitivity, objectivity and interpretability of analysis of multi-subject diffusion imaging studies. We describe TBSS in detail and present example TBSS results from several diffusion imaging studies...
  5. ncbi Acquisition and voxelwise analysis of multi-subject diffusion data with tract-based spatial statistics
    Stephen M Smith
    Oxford University Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, UK
    Nat Protoc 2:499-503. 2007
    ..In this protocol, we describe the MRI data acquisition and analysis protocols required for TBSS studies of localized change in brain connectivity across multiple subjects...
  6. pmc Functional connectomics from resting-state fMRI
    Stephen M Smith
    Oxford Centre for Functional MRI of the Brain FMRIB, University of Oxford, Oxford, UK Electronic address
    Trends Cogn Sci 17:666-82. 2013
    ..Finally, we describe new possibilities resulting from the high-quality rfMRI data being generated by the Human Connectome Project and highlight some upcoming challenges in functional connectomics. ..
  7. pmc Resting-state fMRI in the Human Connectome Project
    Stephen M Smith
    FMRIB Oxford Centre for Functional MRI of the Brain, Oxford University, Oxford, UK
    Neuroimage 80:144-68. 2013
    ....
  8. pmc Temporally-independent functional modes of spontaneous brain activity
    Stephen M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 109:3131-6. 2012
    ..These functionally distinct modes of spontaneous brain activity are, in general, quite different from resting-state networks previously reported, and may have greater biological interpretability...
  9. ncbi Normalized accurate measurement of longitudinal brain change
    S M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, England
    J Comput Assist Tomogr 25:466-75. 2001
    ..New methods of change analysis attempt to improve robustness, accuracy, and extent of automation. A fully automated method has been developed that achieves high estimation accuracy...
  10. ncbi Longitudinal and cross-sectional analysis of atrophy in Alzheimer's disease: cross-validation of BSI, SIENA and SIENAX
    Stephen M Smith
    Oxford University Centre for Functional MRI of the Brain FMRIB, Oxford, UK
    Neuroimage 36:1200-6. 2007
    ..We also compare the SIENA longitudinal measure with atrophy state estimated by SIENAX using just the earliest scan taken from each subject. We show strong correspondence and similar sensitivity to atrophy between all 3 measures...
  11. doi Network modelling methods for FMRI
    Stephen M Smith
    FMRIB Oxford University Centre for Functional MRI of the Brain, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Neuroimage 54:875-91. 2011
    ....
  12. pmc Correspondence of the brain's functional architecture during activation and rest
    Stephen M Smith
    Centre for Functional MRI of the Brain, University of Oxford, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 106:13040-5. 2009
    ..We conclude that the full repertoire of functional networks utilized by the brain in action is continuously and dynamically "active" even when at "rest."..
  13. doi Threshold-free cluster enhancement: addressing problems of smoothing, threshold dependence and localisation in cluster inference
    Stephen M Smith
    FMRIB Oxford University Centre for Functional MRI of the Brain, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Neuroimage 44:83-98. 2009
    ..We also show an example on a real imaging dataset, suggesting that TFCE does indeed provide not just improved sensitivity, but richer and more interpretable output than cluster-based thresholding...
  14. ncbi Fast robust automated brain extraction
    Stephen M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, Oxford University, John Radcliffe Hospital, Headington, Oxford, United Kingdom
    Hum Brain Mapp 17:143-55. 2002
    ..We describe the new method and give examples of results and the results of extensive quantitative testing against "gold-standard" hand segmentations, and two other popular automated methods...
  15. ncbi The danger of systematic bias in group-level FMRI-lag-based causality estimation
    S M Smith
    Oxford Centre for Functional MRI of the Brain FMRIB, Nuffield Department of Clinical Neurosciences, Oxford University, UK
    Neuroimage 59:1228-9. 2012
    ..While many statements in the paper (e.g., the final two sentences) do refer to this problem, we fear that the overriding message that many readers may take from the paper could cause misunderstanding...
  16. pmc Preventing Alzheimer's disease-related gray matter atrophy by B-vitamin treatment
    Gwenaelle Douaud
    Functional Magnetic Resonance Imaging of the Brain FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 110:9523-8. 2013
    ..Further B-vitamin supplementation trials focusing on elderly subjets with high homocysteine levels are warranted to see if progression to dementia can be prevented...
  17. pmc Applying FSL to the FIAC data: model-based and model-free analysis of voice and sentence repetition priming
    Christian F Beckmann
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, University of Oxford, Oxford, UK
    Hum Brain Mapp 27:380-91. 2006
    ..These results suggest that both are processed in a single underlying system without any significant asymmetries for content vs. voice processing...
  18. ncbi Multilevel linear modelling for FMRI group analysis using Bayesian inference
    Mark W Woolrich
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK
    Neuroimage 21:1732-47. 2004
    ..We also demonstrate that we can infer on the top level of multilevel hierarchies by inferring on the levels of the hierarchy separately and passing summary statistics of a noncentral multivariate t distribution between them...
  19. ncbi Adjusting the neuroimaging statistical inferences for nonstationarity
    Gholamreza Salimi-Khorshidi
    Centre for Functional MRI of the Brain FMRIB, University of Oxford, Oxford, UK
    Med Image Comput Comput Assist Interv 12:992-9. 2009
    ....
  20. ncbi Constrained linear basis sets for HRF modelling using Variational Bayes
    Mark W Woolrich
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Neuroimage 21:1748-61. 2004
    ..We use spatial mixture modelling to produce final probabilities of activation and demonstrate increased sensitivity on an FMRI dataset...
  21. ncbi Fully Bayesian spatio-temporal modeling of FMRI data
    Mark W Woolrich
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    IEEE Trans Med Imaging 23:213-31. 2004
    ....
  22. ncbi Mixture models with adaptive spatial regularization for segmentation with an application to FMRI data
    Mark W Woolrich
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    IEEE Trans Med Imaging 24:1-11. 2005
    ..We examine the behavior of this model when applied to artificial data with different spatial characteristics, and to functional magnetic resonance imaging SPMs...
  23. doi Adjusting the effect of nonstationarity in cluster-based and TFCE inference
    Gholamreza Salimi-Khorshidi
    Centre for Functional MRI of the Brain FMRIB, University of Oxford, Oxford, UK
    Neuroimage 54:2006-19. 2011
    ..We also find that adjusting for local smoothness via a separate resampling procedure is more effective at removing nonstationarity than an adjustment via a random field theory based smoothness estimator...
  24. pmc Diffusion imaging of whole, post-mortem human brains on a clinical MRI scanner
    Karla L Miller
    FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
    Neuroimage 57:167-81. 2011
    ..Despite these alterations, diffusion tractography of several major tracts is successfully demonstrated at both resolutions. We also report novel findings of cortical anisotropy and partial volume effects...
  25. ncbi Accurate, robust, and automated longitudinal and cross-sectional brain change analysis
    Stephen M Smith
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, FMRIB, University of Oxford, John Radcliffe Hospital, Headley Way, Headington, Oxford, United Kingdom
    Neuroimage 17:479-89. 2002
    ..The methods provide easy manual review of their output by the automatic production of summary images which show the results of the brain extraction, registration, tissue segmentation, and final atrophy estimation...
  26. doi Asymmetries of the balanced SSFP profile. Part II: white matter
    Karla L Miller
    Centre for Functional MRI of the Brain, University of Oxford, Oxford, UK
    Magn Reson Med 63:396-406. 2010
    ..These results are discussed in the context of previous work studying gradient-recalled echo (GRE) signal behavior in white matter, and it is suggested that these two techniques are detecting closely related phenomena...
  27. doi Language networks in anophthalmia: maintained hierarchy of processing in 'visual' cortex
    Kate E Watkins
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, UK
    Brain 135:1566-77. 2012
    ....
  28. doi Using Gaussian-process regression for meta-analytic neuroimaging inference based on sparse observations
    Gholamreza Salimi-Khorshidi
    FMRIB Centre, University of Oxford, Oxford, UK
    IEEE Trans Med Imaging 30:1401-16. 2011
    ..Our results show that GPR outperforms existing CBMA techniques and is capable of more accurately reproducing the (usually unavailable) full-image analysis results...
  29. pmc MSM: A new flexible framework for Multimodal Surface Matching
    Emma C Robinson
    FMRIB Centre, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, OX3 9DU, UK
    Neuroimage 100:414-26. 2014
    ..In the future, the MSM technique will allow explorations into the best combinations of features and alignment strategies for inter-subject alignment of cortical functional areas for a wide range of neuroimaging data sets. ..
  30. doi FSL
    Mark Jenkinson
    FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, UK
    Neuroimage 62:782-90. 2012
    ..We hope that some of this content might be of interest to users of FSL, and also maybe to new research groups considering creating, releasing and supporting new software packages for brain image analysis...
  31. doi Spontaneous blood oxygenation level-dependent fMRI signal is modulated by behavioral state and correlates with evoked response in sensorimotor cortex: a 7.0-T fMRI study
    Manus J Donahue
    Department of Clinical Neurology, FMRIB Centre, University of Oxford, Oxford, UK
    Hum Brain Mapp 33:511-22. 2012
    ..81; P = 0.03), suggesting that spontaneous signal synchrony may be a predictor of evoked BOLD response magnitude and may account for intersubject variability in sensorimotor cortex...
  32. ncbi Functional-anatomical validation and individual variation of diffusion tractography-based segmentation of the human thalamus
    Heidi Johansen-Berg
    Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Cereb Cortex 15:31-9. 2005
    ..This provides a tool for specific localization of functional activations or lesions to putative thalamic nuclei...
  33. ncbi Resting-state FMRI single subject cortical parcellation based on region growing
    Thomas Blumensath
    Oxford Centre for Functional MRI of the Brain FMRIB Centre, University of Oxford, Oxford, UK
    Med Image Comput Comput Assist Interv 15:188-95. 2012
    ....
  34. pmc Spatially constrained hierarchical parcellation of the brain with resting-state fMRI
    Thomas Blumensath
    FMRIB, University of Oxford, Oxford, UK
    Neuroimage 76:313-24. 2013
    ..Connectivity-derived parcellation borders are less well matched to borders derived from cortical myelination and from cytoarchitectonic atlases, but this may reflect inherent differences in the data...
  35. pmc Tools of the trade: psychophysiological interactions and functional connectivity
    Jill X O'Reilly
    FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Soc Cogn Affect Neurosci 7:604-9. 2012
    ..In this tutorial, we aim to give a simple conceptual explanation of how PPI analysis works, in order to assist readers in planning and interpreting their own PPI experiments...
  36. pmc A Bayesian model of shape and appearance for subcortical brain segmentation
    Brian Patenaude
    FMRIB Centre, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Neuroimage 56:907-22. 2011
    ..7 and 0.9 are obtained with this method, which is comparable or better than other automated methods. An implementation of this method, called FIRST, is currently distributed with the freely-available FSL package...
  37. ncbi Probabilistic independent component analysis for functional magnetic resonance imaging
    Christian F Beckmann
    Medical Vision Laboratory, Department of Engineering Science and the Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford OX3 9DU, UK
    IEEE Trans Med Imaging 23:137-52. 2004
    ..The performance of our approach is illustrated and evaluated on real and artificial FMRI data, and compared to the spatio-temporal accuracy of results obtained from classical ICA and GLM analyses...
  38. ncbi General multilevel linear modeling for group analysis in FMRI
    Christian F Beckmann
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, University of Oxford, Oxford, OX3 9DU, UK
    Neuroimage 20:1052-63. 2003
    ....
  39. ncbi Ventral striatum/nucleus accumbens activation to smoking-related pictorial cues in smokers and nonsmokers: a functional magnetic resonance imaging study
    Sean P David
    Cancer Research United Kingdom General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Radcliffe Infirmary, UK
    Biol Psychiatry 58:488-94. 2005
    ..Converging evidence from several theories of the development of incentive-sensitization to smoking-related environmental stimuli suggests that the ventral striatum plays an important role in the processing of smoking-related cue reactivity...
  40. ncbi Signal and noise characteristics of SSFP FMRI: a comparison with GRE at multiple field strengths
    Karla L Miller
    Centre for Functional MRI of the Brain FMRIB, University of Oxford, Oxford, UK, and A A Martinos Center, Massachusetts General Hospital, Charlestown, USA
    Neuroimage 37:1227-36. 2007
    ..In addition, the temporal noise properties are significantly different, with important implications for SSFP FMRI sequence optimisation...
  41. pmc Automatic denoising of functional MRI data: combining independent component analysis and hierarchical fusion of classifiers
    Gholamreza Salimi-Khorshidi
    Oxford University Centre for Functional MRI of the Brain FMRIB, Oxford, UK Electronic address
    Neuroimage 90:449-68. 2014
    ..FIX is publicly available as a plugin for FSL. ..
  42. doi Resting functional connectivity reveals residual functional activity in Alzheimer's disease
    Giovanna Zamboni
    Oxford Project to Investigate Memory and Ageing, University of Oxford, United Kingdom
    Biol Psychiatry 74:375-83. 2013
    ..We combined resting fMRI and task fMRI to examine the correspondence between these methods in individuals with cognitive impairment...
  43. pmc Investigations into resting-state connectivity using independent component analysis
    Christian F Beckmann
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Philos Trans R Soc Lond B Biol Sci 360:1001-13. 2005
    ..We show that these networks exhibit high spatial consistency across subjects and closely resemble discrete cortical functional networks such as visual cortical areas or sensory-motor cortex...
  44. ncbi Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognition
    Robert D Rogers
    University Department of Psychiatry, Warneford Hospital, Oxford, United Kingdom
    Biol Psychiatry 55:594-602. 2004
    ....
  45. ncbi High-resolution FMRI at 1.5T using balanced SSFP
    Karla L Miller
    Oxford Centre for Functional MRI of the Brain, FMRIB, Oxford University, UK
    Magn Reson Med 55:161-70. 2006
    ..5 T. Currently, the major limitation of BOSS FMRI is its sensitivity to temporal and spatial field drift...
  46. pmc Integrity of white matter in the corpus callosum correlates with bimanual co-ordination skills
    Heidi Johansen-Berg
    Oxford Centre for Functional MRI of the Brain, John Radcliffe Hospital, Headington, Oxford, OX3 0HS, UK
    Neuroimage 36:T16-21. 2007
    ..This provides further evidence for the role of medial wall motor areas in bimanual co-ordination and supports the idea that variation in brain structure reflects inter-individual differences in skilled performance...
  47. ncbi Crossing fibres in tract-based spatial statistics
    Saad Jbabdi
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, University of Oxford, Oxford, UK
    Neuroimage 49:249-56. 2010
    ..We show how this framework applies to the parameters of a crossing fibre model and discuss its implications for voxelwise analysis of the white matter...
  48. pmc Structural and functional abnormalities of the motor system in developmental stuttering
    Kate E Watkins
    Department of Experimental Psychology, University of Oxford, Oxford, UK
    Brain 131:50-9. 2008
    ....
  49. pmc Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele
    Nicola Filippini
    University Department of Psychiatry, University of Oxford, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 106:7209-14. 2009
    ..The APOE epsilon4 allele modulates brain function decades before any clinical or neurophysiological expression of neurodegenerative processes...
  50. ncbi Methods for tractography-driven surface registration of brain structures
    Aleksandar Petrović
    Centre for Functional MRI of the Brain FMRIB, University of Oxford
    Med Image Comput Comput Assist Interv 12:705-12. 2009
    ..The results suggest differences in thalamic connectivity predominantly in the medial dorsal parts of the left thalamus...
  51. ncbi Bayesian analysis of neuroimaging data in FSL
    Mark W Woolrich
    University of Oxford Centre for Functional MRI of the Brain, UK
    Neuroimage 45:S173-86. 2009
    ..Finally, we mention some analysis scenarios where Bayesian methods are impractical, and briefly discuss some practical approaches that we have taken in these cases...
  52. doi Meta-analysis of neuroimaging data: a comparison of image-based and coordinate-based pooling of studies
    Gholamreza Salimi-Khorshidi
    Centre for Functional MRI of the Brain FMRIB, University of Oxford, Oxford, UK
    Neuroimage 45:810-23. 2009
    ..To make IBMA analyses practical, however, the neuroimaging field needs to develop an effective mechanism for sharing image data, including whole-brain images of both effect estimates and their standard errors...
  53. doi What is the most interesting part of the brain?
    Timothy E J Behrens
    Functional MRI of the Brain Centre, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Trends Cogn Sci 17:2-4. 2013
    ..We tested this unstated hypothesis by regressing the journal impact factor against both the pattern of brain activity and the experimental keywords across thousands of brain imaging studies. We found the results to be illuminating...
  54. ncbi Benefits of multi-modal fusion analysis on a large-scale dataset: life-span patterns of inter-subject variability in cortical morphometry and white matter microstructure
    Adrian R Groves
    FMRIB Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, University of Oxford, OX3 9DU, UK
    Neuroimage 63:365-80. 2012
    ..This exploratory approach automatically generates models to explain structure in the data, and may prove especially powerful for large-scale studies, where the population variability can be explored in increased detail...
  55. ncbi Correlation between motor improvements and altered fMRI activity after rehabilitative therapy
    Heidi Johansen-Berg
    Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital and Rivermead Rehabilitation Centre, Oxford, UK
    Brain 125:2731-42. 2002
    ..Our results suggest that activity changes in sensorimotor regions are associated with successful motor rehabilitation...
  56. ncbi On bias in the estimation of autocorrelations for fMRI voxel time-series analysis
    Jonathan L Marchini
    Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, UK
    Neuroimage 18:83-90. 2003
    ..In fact estimates of the model parameters and their standard errors are seen to be so accurate that we conclude that bias correction is unnecessary...
  57. doi Relationships of brain white matter microstructure with clinical and MR measures in relapsing-remitting multiple sclerosis
    Antonio Giorgio
    Centre for Functional MRI of the Brain, University of Oxford, Oxford, UK
    J Magn Reson Imaging 31:309-16. 2010
    ....
  58. pmc Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial
    A David Smith
    Oxford Project to Investigate Memory and Ageing, University of Oxford, Oxford, United Kingdom
    PLoS ONE 5:e12244. 2010
    ..Homocysteine is a risk factor for brain atrophy, cognitive impairment and dementia. Plasma concentrations of homocysteine can be lowered by dietary administration of B vitamins...
  59. pmc Permutation inference for the general linear model
    Anderson M Winkler
    Oxford Centre for Functional MRI of the Brain, University of Oxford, Oxford, UK Global Imaging Unit, GlaxoSmithKline, London, UK Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA Electronic address
    Neuroimage 92:381-97. 2014
    ..Detailed examples of common neuroimaging applications are provided, as well as a complete algorithm - the "randomise" algorithm - for permutation inference with the GLM...
  60. doi Increased resting state functional connectivity in the default mode network in recovered anorexia nervosa
    Felicity A Cowdrey
    University of Oxford Department of Psychiatry, Warneford Hospital, Oxford, United Kingdom
    Hum Brain Mapp 35:483-91. 2014
    ..The findings support the view that dysfunction in resting state functional connectivity in regions involved in self-referential processing and cognitive control might be a vulnerability marker for the development of anorexia nervosa...
  61. ncbi Imaging how attention modulates pain in humans using functional MRI
    Susanna J Bantick
    Oxford University Department of Clinical Neurology, Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, Headington, Oxford, UK
    Brain 125:310-9. 2002
    ..In contrast, many areas of the pain matrix (i.e. thalamus, insula, cognitive division of the ACC) displayed reduced activation, supporting the behavioural results of reduced pain perception...
  62. ncbi Concurrent numerical simulation of flow and blood clotting using the lattice Boltzmann technique
    Jorg Bernsdorf
    C and C Research Laboratories, NEC Europe Ltd, Rathausallee 10, Sankt Augustin, Germany
    Int J Bioinform Res Appl 2:371-80. 2006
    ..The applied numerical scheme is the lattice Boltzmann technique, which proved to be highly efficient particularly for transient flows and complex or varying geometries...
  63. ncbi Monitoring disease activity and progression in primary progressive multiple sclerosis using MRI: sub-voxel registration to identify lesion changes and to detect cerebral atrophy
    Valerie L Stevenson
    NMR Research Unit, Institute of Neurology, London
    J Neurol 249:171-7. 2002
    ....
  64. ncbi Regional brain atrophy development is related to specific aspects of clinical dysfunction in multiple sclerosis
    Bas Jasperse
    Department of Neurology, VU University Medical Center, Boelelaan 1117, PO Box 7057, 1007 MB, Amsterdam, The Netherlands
    Neuroimage 38:529-37. 2007
    ....
  65. ncbi Intercenter agreement of brain atrophy measurement in multiple sclerosis patients using manually-edited SIENA and SIENAX
    Bas Jasperse
    Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands
    J Magn Reson Imaging 26:881-5. 2007
    ....
  66. doi Are baroreflex events detected by invasive and non-invasive techniques coincident?
    Stephen M Smith
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Clin Physiol Funct Imaging 28:262-9. 2008
    ..Non-invasive, compared with intra-arterial estimates of BRS by sequence analysis are not influenced by coincidence of sequences if acceptance of sequences is based on the correlation coefficient criteria (>0.85)...
  67. ncbi Recordings from single neocortical nerve terminals reveal a nonselective cation channel activated by decreases in extracellular calcium
    Stephen M Smith
    Department of Molecular and Cellular Physiology, Stanford University School of Medicine, CA 94305, USA
    Neuron 41:243-56. 2004
    ..Activation of NSC channels by falls in [Ca(2+)](o) would be expected during periods of high activity in the neocortex and may modulate the excitability of the presynaptic terminal...
  68. pmc Vasopressin inhibits glutamate release via two distinct modes in the brainstem
    Timothy W Bailey
    Department of Physiology and Pharmacology, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    J Neurosci 26:6131-42. 2006
    ..Thus, AVP regulates NTS neurons by two distinct novel and state-dependent mechanisms: one, an analog, graded presynaptic inhibition of terminal glutamate release and the other, a binary, extraterminal block of conducted excitation...
  69. ncbi Manifestations of early brain recovery associated with abstinence from alcoholism
    Andreas J Bartsch
    University of Wurzburg, Department of Neuroradiology, Wurzburg, Germany
    Brain 130:36-47. 2007
    ..Further understanding of the precise mechanisms of this recovery may become a valuable model of brain regeneration with relevance for other disorders...
  70. ncbi Measuring brain atrophy in multiple sclerosis
    Nicola De Stefano
    Department of Neurological and Behavioural Sciences, University of Siena, Italy
    J Neuroimaging 17:10S-15S. 2007
    ..It represents one of most promising in vivo measures of neuroaxonal degeneration in MS, and it should be used extensively in the future to assess and monitor pathological evolution and treatment efficacy in this disease...
  71. ncbi Influence of noninvasive peripheral arterial blood pressure measurements on assessment of dynamic cerebral autoregulation
    Emily L Sammons
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    J Appl Physiol 103:369-75. 2007
    ....
  72. ncbi Sensitivity and specificity of the blankenship FCE system's indicators of submaximal effort
    Perry N Brubaker
    North Georgia College and State University, Dahlonega, GA, USA
    J Orthop Sports Phys Ther 37:161-8. 2007
    ..Single-blinded, randomized, posttest only design...
  73. pmc Modulation of neuronal voltage-activated calcium and sodium channels by polyamines and pH
    Wenyan Chen
    Division of Pulmonary and Critical Care Medicine, Oregon Health and Science University, Portland, Oregon, USA
    Channels (Austin) 1:281-90. 2007
    ..Many of the observed effects can be explained by a model incorporating polyamine binding, H(+) binding and surface charge screening...
  74. doi Enhanced brain extraction improves the accuracy of brain atrophy estimation
    Marco Battaglini
    Department of Neurological and Behavioural Sciences, University of Siena, Italy
    Neuroimage 40:583-9. 2008
    ..Multicentre studies monitoring brain atrophy in clinical trials may receive benefit by using this unbiased, fully automated procedure...