Noel H Smith

Summary

Affiliation: University of Sussex
Country: UK

Publications

  1. doi request reprint The global distribution and phylogeography of Mycobacterium bovis clonal complexes
    Noel H Smith
    Animal Health and Veterinary Laboratories Agency, Weybridge, New Haw, Surrey KT15 3NB, UK
    Infect Genet Evol 12:857-65. 2012
  2. doi request reprint Naming spoligotype patterns for the RD9-deleted lineage of the Mycobacterium tuberculosis complex; www.Mbovis.org
    Noel H Smith
    Centre for the Study of Evolution, University of Sussex and Animal Health and Veterinary Laboratories Agency, Weybridge, New Haw, Surrey KT15 3NB, UK
    Infect Genet Evol 12:873-6. 2012
  3. ncbi request reprint Ecotypes of the Mycobacterium tuberculosis complex
    Noel H Smith
    TB Research Group, Veterinary Laboratories Agency, VLA, Addlestone, Surrey KT15 3NB, UK
    J Theor Biol 239:220-5. 2006
  4. doi request reprint European 1: a globally important clonal complex of Mycobacterium bovis
    Noel H Smith
    Centre for Study of Evolution, University of Sussex, Animal Health and Veterinary Laboratories Agency, Weybridge, New Haw, Surrey KT15 3NB, UK
    Infect Genet Evol 11:1340-51. 2011
  5. doi request reprint Myths and misconceptions: the origin and evolution of Mycobacterium tuberculosis
    Noel H Smith
    Veterinary Laboratories Agency VLA, Weybridge, New Haw, Addlestone, Surrey KT15 3NB, UK
    Nat Rev Microbiol 7:537-44. 2009
  6. pmc Mycobacterium microti: More diverse than previously thought
    N H Smith
    VLA Weybridge, New Haw, Surrey, United Kingdom
    J Clin Microbiol 47:2551-9. 2009
  7. pmc Molecular characterisation of Mycobacterium bovis isolated from cattle slaughtered at the Bamako abattoir in Mali
    Borna Muller
    Swiss Tropical Institute, Basel, Switzerland
    BMC Vet Res 4:26. 2008
  8. pmc Molecular characterization of Mycobacterium bovis strains isolated from cattle slaughtered at two abattoirs in Algeria
    Naima Sahraoui
    Département Vétérinaire, Université Saad Dahlab, Blida, Algeria
    BMC Vet Res 5:4. 2009
  9. pmc African 2, a clonal complex of Mycobacterium bovis epidemiologically important in East Africa
    Stefan Berg
    VLA Weybridge, New Haw, Surrey KT15 3NB, United Kingdom
    J Bacteriol 193:670-8. 2011
  10. pmc The population structure of Mycobacterium bovis in Great Britain: clonal expansion
    Noel H Smith
    Centre for the Study of Evolution, University of Sussex, Falmer, Brighton BN1 9QL, United Kingdom
    Proc Natl Acad Sci U S A 100:15271-5. 2003

Collaborators

Detail Information

Publications13

  1. doi request reprint The global distribution and phylogeography of Mycobacterium bovis clonal complexes
    Noel H Smith
    Animal Health and Veterinary Laboratories Agency, Weybridge, New Haw, Surrey KT15 3NB, UK
    Infect Genet Evol 12:857-65. 2012
    ..bovis clonal complexes has shown surprising geographical localisation of molecular types but also hints strongly that much of the worldwide distribution of bovine pathogen resulted from human trade in cattle within the last 200 years...
  2. doi request reprint Naming spoligotype patterns for the RD9-deleted lineage of the Mycobacterium tuberculosis complex; www.Mbovis.org
    Noel H Smith
    Centre for the Study of Evolution, University of Sussex and Animal Health and Veterinary Laboratories Agency, Weybridge, New Haw, Surrey KT15 3NB, UK
    Infect Genet Evol 12:873-6. 2012
    ..bovis. The history of the database is described, as well as the method for submitting new patterns to the database and the functionality of the website...
  3. ncbi request reprint Ecotypes of the Mycobacterium tuberculosis complex
    Noel H Smith
    TB Research Group, Veterinary Laboratories Agency, VLA, Addlestone, Surrey KT15 3NB, UK
    J Theor Biol 239:220-5. 2006
    ..Finally, we discuss the application of the ecotype concept to this series of clades and suggest that the M. tuberculosis complex may best be described as a series of host-adapted ecotypes...
  4. doi request reprint European 1: a globally important clonal complex of Mycobacterium bovis
    Noel H Smith
    Centre for Study of Evolution, University of Sussex, Animal Health and Veterinary Laboratories Agency, Weybridge, New Haw, Surrey KT15 3NB, UK
    Infect Genet Evol 11:1340-51. 2011
    ..bovis and indicates that much of the current global distribution of this important veterinary pathogen has resulted from relatively recent International trade in cattle...
  5. doi request reprint Myths and misconceptions: the origin and evolution of Mycobacterium tuberculosis
    Noel H Smith
    Veterinary Laboratories Agency VLA, Weybridge, New Haw, Addlestone, Surrey KT15 3NB, UK
    Nat Rev Microbiol 7:537-44. 2009
    ..We discuss a series of misconceptions about the origin of both M. tuberculosis and the disease it causes that have arisen over the years, and identify a number of unanswered questions that could provide insight into both these areas...
  6. pmc Mycobacterium microti: More diverse than previously thought
    N H Smith
    VLA Weybridge, New Haw, Surrey, United Kingdom
    J Clin Microbiol 47:2551-9. 2009
    ..The location of the cats with M. microti infection suggests that they do not overlap geographically with the strains of Mycobacterium bovis in Great Britain...
  7. pmc Molecular characterisation of Mycobacterium bovis isolated from cattle slaughtered at the Bamako abattoir in Mali
    Borna Muller
    Swiss Tropical Institute, Basel, Switzerland
    BMC Vet Res 4:26. 2008
    ..Of 3330 animals screened only 60 exhibited gross visible lesions. From these animals, twenty strains of M. bovis were isolated and characterised by spoligotyping...
  8. pmc Molecular characterization of Mycobacterium bovis strains isolated from cattle slaughtered at two abattoirs in Algeria
    Naima Sahraoui
    Département Vétérinaire, Université Saad Dahlab, Blida, Algeria
    BMC Vet Res 5:4. 2009
    ..In 260 animals, gross visible granulomatous lesions were detected and put into culture. Bacterial isolates were subsequently analysed by molecular methods...
  9. pmc African 2, a clonal complex of Mycobacterium bovis epidemiologically important in East Africa
    Stefan Berg
    VLA Weybridge, New Haw, Surrey KT15 3NB, United Kingdom
    J Bacteriol 193:670-8. 2011
    ..bovis have, in general, four or more copies of the insertion sequence IS6110, in contrast to the majority of M. bovis strains isolated from cattle, which are thought to carry only one or a few copies...
  10. pmc The population structure of Mycobacterium bovis in Great Britain: clonal expansion
    Noel H Smith
    Centre for the Study of Evolution, University of Sussex, Falmer, Brighton BN1 9QL, United Kingdom
    Proc Natl Acad Sci U S A 100:15271-5. 2003
    ..A similar pattern is observed in M. tuberculosis (the main cause of tuberculosis in humans). The significance of clonal expansion in other bacteria that have recombination is discussed...
  11. ncbi request reprint Bottlenecks and broomsticks: the molecular evolution of Mycobacterium bovis
    Noel H Smith
    Veterinary Laboratories Agency, Weybridge, New Haw, Addlestone, Surrey, KT15 3NB UK
    Nat Rev Microbiol 4:670-81. 2006
    ..We also discuss the practical implications of applying this knowledge to understanding the spread of infection and the development of improved vaccines and diagnostic tests...
  12. ncbi request reprint Recent advances in our knowledge of Mycobacterium bovis: a feeling for the organism
    R Glyn Hewinson
    TB Research Group, Veterinary Laboratories Agency, Weybridge, Addlestone, Surrey KT15 3NB, UK
    Vet Microbiol 112:127-39. 2006
    ..bovis and BCG will allow insight into how BCG became attenuated following serial passage on artificial growth media and reveal clues into how to improve the vaccine efficacy of BCG...
  13. pmc The burden of mycobacterial disease in ethiopian cattle: implications for public health
    Stefan Berg
    TB Research Group, Veterinary Laboratories Agency, Weybridge, New Haw, Addlestone, Surrey, United Kingdom
    PLoS ONE 4:e5068. 2009
    ..Furthermore, Ethiopia has one of the highest incidence rates of human extrapulmonary TB in the world, a clinical presentation that is often associated with transmission of M. bovis from cattle to humans...