Craig J Smith

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. pmc Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production
    Hedley C A Emsley
    Division of Neuroscience, The University of Liverpool, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool L9 7LJ, UK
    BMC Neurol 7:5. 2007
  2. pmc Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome
    Craig J Smith
    University of Manchester, Manchester M13 9PT, UK
    BMC Neurol 4:2. 2004
  3. ncbi request reprint Variability of the systemic acute phase response after ischemic stroke
    Craig J Smith
    Division of Medicine and Neurosciences, University of Manchester, Clinical Sciences Building, Hope Hospital, Salford, UK
    J Neurol Sci 251:77-81. 2006
  4. ncbi request reprint An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis
    Hedley C A Emsley
    University of Manchester, Manchester, UK
    J Neuroimmunol 139:93-101. 2003
  5. doi request reprint Diagnosis of Stroke-Associated Pneumonia: Recommendations From the Pneumonia in Stroke Consensus Group
    Craig J Smith
    From the Stroke and Vascular Research Centre C J S, A K K, S J H, P J T and Centre for Biostatistics A V, University of Manchester, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, Salford, United Kingdom Comprehensive Stroke Center, Department of Neuroscience, Hospital Clinic, University of Barcelona, Barcelona, Spain A C Department of Medicine, Hospital Universitari Mutua de Terrassa, Barcelona, Spain J G Neurological Service, San Camillo de Lellis General Hospital, Rieti, Italy M D N Clinical Neurosciences, King s College Hospital NHS Foundation Trust, London, United Kingdom L K Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom P L Laboratorio de Investigación Neurovascular, Unidad Neurovascular, Servicio de Neurología Hospital Vall d Hebron, Barcelona, Spain J M IBIS Stroke Programme, Hospital Virgen del Rocio, Sevilla, Spain J M Keele University Institute for Science and Technology in Medicine, Guy Hilton Research Centre, Stoke on Trent, United Kingdom C R Department of Health and Social Care, Kings College, London, Germany
    Stroke 46:2335-40. 2015
  6. doi request reprint Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression
    Craig J Smith
    Brain Injury Research Group, School of Biomedicine, University of Manchester, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, Salford M6 8HD, UK
    Cytokine 58:384-9. 2012
  7. ncbi request reprint Reliability of a semi-automated technique of cerebral infarct volume measurement with CT
    Carole M Gavin
    University of Manchester and Stroke Services, Hope Hospital, Salford, UK
    Cerebrovasc Dis 18:220-6. 2004
  8. doi request reprint Detection of atrial fibrillation after ischemic stroke or transient ischemic attack: a systematic review and meta-analysis
    Amit Kishore
    From the Stroke and Vascular Research Centre, Institute of Cardiovascular Sciences A K, P J T, C J S and Centre for Biostatistics A V, University of Manchester, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, Salford, United Kingdom Greater Manchester Comprehensive Stroke Centre, Department of Medical Neurosciences, Salford Royal Foundation Trust, Salford, United Kingdom A K, A M, P J T, C J S and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow, United Kingdom J D, K R L
    Stroke 45:520-6. 2014
  9. doi request reprint Systematic review and meta-analysis of the efficacy of statins in experimental stroke
    Hardaman K Baryan
    Brain Injury Research Group, School of Biomedicine, University of Manchester, UK
    Int J Stroke 7:150-6. 2012
  10. doi request reprint How is pneumonia diagnosed in clinical stroke research? A systematic review and meta-analysis
    Amit K Kishore
    From the Stroke and Vascular Research Centre, University of Manchester, Institute of Cardiovascular Sciences, Greater Manchester Comprehensive Stroke Centre Salford Royal Foundation Trust, UK A K K, S J H, P J T, C J S Centre for Biostatistics, University of Manchester, Salford Royal Foundation Trust, UK A V Comprehensive Stroke Center, Department of Neuroscience, Hospital Clinic, University of Barcelona, Barcelona, Spain A C Department of Medicine, Hospital Universitari Mutua de Terrassa, Barcelona, Spain J G Neurological Service, San Camillo de Lellis General Hospital, Rieti, Italy M D N Clinical Neurosciences, King s College Hospital NHS Foundation Trust London, UK L K Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK P L Laboratorio de Investigación Neurovascular, Unidad Neurovascular, Servicio de Neurología Hospital Vall d Hebron, Barcelona J M IBIS Stroke Programme, Hospital Virgen del Rocio, Sevilla, Spain J M Keele University Institute for Science and Technology in Medicine, Guy Hilton Research Centre, Stoke on Trent, UK C R Department of Health and Social Care, Osaka 565-0871
    Stroke 46:1202-9. 2015

Collaborators

Detail Information

Publications18

  1. pmc Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production
    Hedley C A Emsley
    Division of Neuroscience, The University of Liverpool, The Walton Centre for Neurology and Neurosurgery, Lower Lane, Liverpool L9 7LJ, UK
    BMC Neurol 7:5. 2007
    ....
  2. pmc Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome
    Craig J Smith
    University of Manchester, Manchester M13 9PT, UK
    BMC Neurol 4:2. 2004
    ..We assessed the relationship between peak values of plasma interleukin-6 (IL-6) in the first week after ischaemic stroke, with measures of stroke severity and outcome...
  3. ncbi request reprint Variability of the systemic acute phase response after ischemic stroke
    Craig J Smith
    Division of Medicine and Neurosciences, University of Manchester, Clinical Sciences Building, Hope Hospital, Salford, UK
    J Neurol Sci 251:77-81. 2006
    ..These data suggest that, although infection and other factors may contribute to systemic inflammation, the extent of acute brain injury after ischemic stroke is a major factor influencing the magnitude and variability of the APR...
  4. ncbi request reprint An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis
    Hedley C A Emsley
    University of Manchester, Manchester, UK
    J Neuroimmunol 139:93-101. 2003
    ....
  5. doi request reprint Diagnosis of Stroke-Associated Pneumonia: Recommendations From the Pneumonia in Stroke Consensus Group
    Craig J Smith
    From the Stroke and Vascular Research Centre C J S, A K K, S J H, P J T and Centre for Biostatistics A V, University of Manchester, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, Salford, United Kingdom Comprehensive Stroke Center, Department of Neuroscience, Hospital Clinic, University of Barcelona, Barcelona, Spain A C Department of Medicine, Hospital Universitari Mutua de Terrassa, Barcelona, Spain J G Neurological Service, San Camillo de Lellis General Hospital, Rieti, Italy M D N Clinical Neurosciences, King s College Hospital NHS Foundation Trust, London, United Kingdom L K Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom P L Laboratorio de Investigación Neurovascular, Unidad Neurovascular, Servicio de Neurología Hospital Vall d Hebron, Barcelona, Spain J M IBIS Stroke Programme, Hospital Virgen del Rocio, Sevilla, Spain J M Keele University Institute for Science and Technology in Medicine, Guy Hilton Research Centre, Stoke on Trent, United Kingdom C R Department of Health and Social Care, Kings College, London, Germany
    Stroke 46:2335-40. 2015
    ..The aim of this consensus was to propose standardized terminology and operational diagnostic criteria for lower respiratory tract infections complicating acute stroke...
  6. doi request reprint Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression
    Craig J Smith
    Brain Injury Research Group, School of Biomedicine, University of Manchester, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, Salford M6 8HD, UK
    Cytokine 58:384-9. 2012
    ....
  7. ncbi request reprint Reliability of a semi-automated technique of cerebral infarct volume measurement with CT
    Carole M Gavin
    University of Manchester and Stroke Services, Hope Hospital, Salford, UK
    Cerebrovasc Dis 18:220-6. 2004
    ..We investigated the reproducibility of a semi-automated method of computed tomography (CT) infarct volume measurement amongst three stroke research fellows with no formal neuroradiology training and two consultant neuroradiologists...
  8. doi request reprint Detection of atrial fibrillation after ischemic stroke or transient ischemic attack: a systematic review and meta-analysis
    Amit Kishore
    From the Stroke and Vascular Research Centre, Institute of Cardiovascular Sciences A K, P J T, C J S and Centre for Biostatistics A V, University of Manchester, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, Salford, United Kingdom Greater Manchester Comprehensive Stroke Centre, Department of Medical Neurosciences, Salford Royal Foundation Trust, Salford, United Kingdom A K, A M, P J T, C J S and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Western Infirmary, Glasgow, United Kingdom J D, K R L
    Stroke 45:520-6. 2014
    ..We therefore undertook a systematic review and meta-analysis to determine the frequency of newly detected AF using noninvasive or invasive cardiac monitoring after ischemic stroke or transient ischemic attack...
  9. doi request reprint Systematic review and meta-analysis of the efficacy of statins in experimental stroke
    Hardaman K Baryan
    Brain Injury Research Group, School of Biomedicine, University of Manchester, UK
    Int J Stroke 7:150-6. 2012
    ..Statins are postulated as candidate drugs for the treatment of acute stroke. The aim of this study was to critically appraise the evidence for the efficacy of statins administered after the onset of experimental focal cerebral ischemia...
  10. doi request reprint How is pneumonia diagnosed in clinical stroke research? A systematic review and meta-analysis
    Amit K Kishore
    From the Stroke and Vascular Research Centre, University of Manchester, Institute of Cardiovascular Sciences, Greater Manchester Comprehensive Stroke Centre Salford Royal Foundation Trust, UK A K K, S J H, P J T, C J S Centre for Biostatistics, University of Manchester, Salford Royal Foundation Trust, UK A V Comprehensive Stroke Center, Department of Neuroscience, Hospital Clinic, University of Barcelona, Barcelona, Spain A C Department of Medicine, Hospital Universitari Mutua de Terrassa, Barcelona, Spain J G Neurological Service, San Camillo de Lellis General Hospital, Rieti, Italy M D N Clinical Neurosciences, King s College Hospital NHS Foundation Trust London, UK L K Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK P L Laboratorio de Investigación Neurovascular, Unidad Neurovascular, Servicio de Neurología Hospital Vall d Hebron, Barcelona J M IBIS Stroke Programme, Hospital Virgen del Rocio, Sevilla, Spain J M Keele University Institute for Science and Technology in Medicine, Guy Hilton Research Centre, Stoke on Trent, UK C R Department of Health and Social Care, Osaka 565-0871
    Stroke 46:1202-9. 2015
    ....
  11. doi request reprint Phase II anti-inflammatory and immune-modulating drugs for acute ischaemic stroke
    Craig J Smith
    Greater Manchester Comprehensive Stroke Centre, Department of Medical Neurosciences, Salford Royal Foundation Trust, Salford, UK
    Expert Opin Investig Drugs 24:623-43. 2015
    ..Although anti-inflammatory drugs have already failed in clinical trial development, several are currently at the Phase II developmental stage...
  12. pmc Can a novel clinical risk score improve pneumonia prediction in acute stroke care? A UK multicenter cohort study
    Craig J Smith
    Stroke and Vascular Research Centre, Institute of Cardiovascular Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK C J S, P J T Greater Manchester Comprehensive Stroke Centre, Department of Medical Neurosciences, Salford Royal NHS Foundation Trust, Salford, UK C J S, P J T
    J Am Heart Assoc 4:e001307. 2015
    ..We derived and internally validated a simple clinical risk score for predicting stroke-associated pneumonia (SAP), and compared the performance with an existing score (A(2)DS(2))...
  13. doi request reprint Incidence, predictors and clinical characteristics of orolingual angio-oedema complicating thrombolysis with tissue plasminogen activator for ischaemic stroke
    Robert Hurford
    Stroke and Vascular Research Centre, Institute of Cardiovascular Sciences, University of Manchester, Manchester Academic Health Science Centre, Salford Royal NHS Foundation Trust, Manchester, UK Comprehensive Stroke Centre, Greater Manchester Neurosciences Centre, Salford Royal NHS Foundation Trust, Manchester, UK
    J Neurol Neurosurg Psychiatry 86:520-3. 2015
    ..We investigated its incidence, clinical characteristics and relationship with other factors in patients receiving tPA at a UK centre...
  14. ncbi request reprint Current and emerging treatments for acute stroke: relationships with infection
    Craig J Smith
    Brain Injury Research Group, University of Manchester, Clinical Sciences Building, Salford Royal Foundation Trust, Salford M6 8HD, UK
    Infect Disord Drug Targets 10:112-21. 2010
    ..In this review we discuss the role of current and emerging treatments for stroke and their effects on infection, considering possible underlying mechanisms and implications for the development of new therapies...
  15. ncbi request reprint Correlation of systemic inflammatory response with infarct volume in acute ischemic stroke patients
    Hedley C A Emsley
    Stroke 36:228-9; author reply 228-9. 2005
  16. ncbi request reprint Evaluation of C-reactive protein measurement for assessing the risk and prognosis in ischemic stroke: a statement for health care professionals from the CRP Pooling Project members
    Mario Di Napoli
    San Camillo de Lellis General Hospital, Rieti, Italy
    Stroke 36:1316-29. 2005
    ..The aim of this review is to summarize the evidence for CRP as an independent predictor of cerebrovascular events in at-risk individuals and ischemic stroke patients and to consider its usefulness in evaluating prognosis after stroke...
  17. ncbi request reprint Inflammation in acute ischemic stroke and its relevance to stroke critical care
    Hedley C A Emsley
    Division of Neuroscience, The Walton Centre for Neurology and Neurosurgery, The University of Liverpool, Liverpool, L9 7LJ, UK
    Neurocrit Care 9:125-38. 2008
    ....
  18. ncbi request reprint Infection and brain-induced immunodepression after acute ischemic stroke
    Hedley C A Emsley
    Stroke 39:e7; author reply e8. 2008