Affiliation: University College London
- Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaborationColette J Smith
Research Department of Infection and Population Health, University College London, London, UK Electronic address
Lancet 384:241-8. 2014..Consequently, the relative importance of other traditionally non-AIDS-related morbidities has increased. We investigated trends over time in all-cause mortality and for specific causes of death in people with HIV from 1999 to 2011...
- Factors associated with specific causes of death amongst HIV-positive individuals in the D:A:D StudyColette Smith
Research Department of Infection and Population Health, UCL, Royal Free Campus, London, UK
AIDS 24:1537-48. 2010..To investigate any emerging trends in causes of death amongst HIV-positive individuals in the current cART era, and to investigate the factors associated with each specific cause of death...
- Estimated average annual rate of change of CD4(+) T-cell counts in patients on combination antiretroviral therapyAmanda Mocroft
Research Department of Infection and Population Health, University College London Medical School, London, UK
Antivir Ther 15:563-70. 2010..Patients receiving combination antiretroviral therapy (cART) might continue treatment with a virologically failing regimen. We sought to identify annual change in CD4(+) T-cell count according to levels of viraemia in patients on cART...
- Outcomes in the first year after initiation of first-line HAART among heterosexual men and women in the UK CHIC StudyTristan J Barber
St Stephen s AIDS Trust Clinical Trials Unit, Chelsea and Westminster NHS Foundation Trust, London, UK
Antivir Ther 16:805-14. 2011..We analysed the influence of gender on use and outcomes of first-line HAART in a UK cohort...
- Data linkage reduces loss to follow-up in an observational HIV cohort studyTeresa Hill
Research Department of Infection and Population Health, UCL Medical School, London, UK
J Clin Epidemiol 63:1101-9. 2010..To ascertain the degree of loss to follow-up in a cohort and to identify its predictors...
- Discordant responses on starting highly active antiretroviral therapy: suboptimal CD4 increases despite early viral suppression in the UK Collaborative HIV Cohort (UK CHIC) StudyR J C Gilson
Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, University College London, The Mortimer Market Centre, Camden Primary Care Trust, London, UK
HIV Med 11:152-60. 2010..This study was designed to determine the incidence of a discordant response at two time-points, soon after 6 months and at 12 months, and to determine the relationship with clinical outcomes...
- The impact of HIV drug resistance testing on changes to treatmentLoveleen Bansi
Research Department of Infection and Population Health, UCL Medical School, UK
AIDS 25:603-10. 2011..We investigate changes made to therapy after a resistance test result and identify factors associated with switching regimen...
- Determinants of virological failure after successful viral load suppression in first-line highly active antiretroviral therapyAnna M Geretti
Royal Free and University College Medical School, London, UK
Antivir Ther 13:927-36. 2008....
- Predictors and kinetics of occult hepatitis B virus infection in HIV-infected personsGaia Nebbia
Department of Virology, Royal Free Hospital and Royal Free and University College Medical School, London, UK
J Med Virol 79:1464-71. 2007..The intermittent nature of HBV-DNA detection poses a diagnostic challenge, but no association is observed with ALT levels...
- The effect of transmitted HIV-1 drug resistance on pre-therapy viral loadLinda Harrison
HIV and Infections Group, MRC Clinical Trials Unit, London, UK
AIDS 24:1917-22. 2010..Reduced replication capacity of viruses expressing drug resistant mutations implies that patients with transmitted drug resistance (TDR) could have lower HIV RNA viral load than those infected with wild-type virus...
- Predictors of advanced chronic kidney disease and end-stage renal disease in HIV-positive personsLene Ryom
aCopenhagen HIV Programme, University of Copenhagen, Faculty of Health and Medical Sciences and Epidemiklinikken M5132, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark bResearch Department of Infection and Population Health, UCL, London, UK cDivision of Nephrology, Mount Sinai School of Medicine, New York, USA dAcademic Medical Center, University of Amsterdam, and Stichting HIV Monitoring, The Netherlands eClinic for Infectious Diseases and Hospital Hygiene, Kantonsspital Aarau, Switzerland fService de médecine interne et maladies infectieuses, Hôpital Saint André, CHU de Bordeaux gNephrology Department, Public Health Department, CHU Nice, France hICAP Columbia University and Harlem Hospital, New York, USA iKirby Institute, Sydney, Australia
AIDS 28:187-99. 2014..Whilst several antiretroviral drugs have been associated with moderate chronic kidney disease (CKD), their contribution to advanced CKD and end-stage renal disease (ESRD) remain unknown...
- Responses to switching to maraviroc-based antiretroviral therapy in treated patients with suppressed plasma HIV-1-RNA loadPaola Vitiello
UCL Medical School, London, UK
Intervirology 55:172-8. 2012..The aim of this study was to evaluate patients on suppressive ART switching to an MVC-containing regimen (MVC-CR), and test the hypothesis that the switch may have an impact on T cell activation...
- Factors influencing lopinavir and atazanavir plasma concentrationWolfgang Stöhr
MRC Clinical Trials Unit, London, UK
J Antimicrob Chemother 65:129-37. 2010..The aim of this study was to evaluate which demographic factors and concomitant drugs are associated with lopinavir and atazanavir plasma concentration...
- Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trialPaul D Griffiths
Centre for Virology, UCL Medical School, London, UK
Lancet 377:1256-63. 2011..Values of viral load correlate with development of end-organ disease and are moderated by pre-existing natural immunity. Our aim was to determine whether vaccine-induced immunity could do likewise...
- Late diagnosis in the HAART era: proposed common definitions and associations with mortalityCaroline A Sabin
Research Department of Infection and Population Health, UCL Medical School, London, UK
AIDS 24:723-7. 2010....
- Characteristics of Epstein-Barr viraemia in adult liver transplant patients: A retrospective cohort studyNeil Halliday
Department of Virology, Royal Free London NHS Foundation Trust, London, UK
Transpl Int 27:838-46. 2014..001) but shortened with ganciclovir exposure (P = 0.06). Younger patients were more likely to have high peak viral loads (P = 0.07). No clinical signs or symptoms or adverse outcomes were associated with EBV reactivation. ..
- The associations between age and the development of laboratory abnormalities and treatment discontinuation for reasons other than virological failure in the first year of highly active antiretroviral therapyC A Sabin
Department of Primary Care and Population Science, Royal Free and UC Medical School, London, UK
HIV Med 10:35-43. 2009....
- Clinical epidemiology of HIV-associated end-stage renal failure in the UKLoveleen Bansi
University College London Medical School, London, UK
AIDS 23:2517-21. 2009..To describe the clinical epidemiology of HIV-associated end-stage renal failure (HIV/ESRF) from 1998 to 2007 in the United Kingdom...
- Acetyl-l-carnitine: a pathogenesis based treatment for HIV-associated antiretroviral toxic neuropathyAndrew M Hart
Blond McIndoe Centre, Royal Free and University College Medical School, London, UK
AIDS 18:1549-60. 2004..ALCAR enhances neurotrophic support of sensory neurons and promotes energy metabolism, potentially causing nerve regeneration and symptom relief...
- Will antiretroviral therapy reduce HIV-related liver risk?Joanna Allen
aDepartment of Infectious Diseases and HIV Medicine bResearch Department of Infection and Population Health, UCL, Royal Free Campus, London, United Kingdom
Curr Opin HIV AIDS 9:48-53. 2014..This article reviews the positive and potential negative impact of cART on liver-related morbidity and mortality...
- Impact of UK academic foundation programmes on aspirations to pursue a career in academiaOliver T A Lyons
Academic Department of Surgery, St Thomas Hospital, London, UK
Med Educ 44:996-1005. 2010..This study aimed to determine the role played by academic foundation programmes in influencing junior doctors' desire to pursue a career in academic medicine...
- Fibroblast growth factor 23 and soluble klotho in children with chronic kidney diseaseMandy Wan
Renal Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
Nephrol Dial Transplant 28:153-61. 2013..There are scarce data on the levels of its essential co-receptor klotho, and longitudinal changes in FGF23 levels are also unknown...
- Reconstitution of herpes simplex virus-specific T cell immunity in HIV-infected patients receiving highly active antiretroviral therapyMeghna Ramaswamy
Department of Virology, Royal Free Hospital and Royal Free and University College Medical School, North Middlesex University Hospital, London, UK
J Infect Dis 195:410-5. 2007..6/month (95% confidence interval, 1.2-9.9 [P=.01]) and 21.3/100 CD4 cells/mm(3) gained (95% confidence interval, 13.8-28.7 [P<.0001]). Responses were correlated with LTNP status and CD4 cell count...
- Prospective monitoring of Epstein-Barr virus DNA in adult renal transplant recipients during the early posttransplant period: role of mycophenolate mofetilMichael V Holmes
Centre for Virology, Royal Free Campus, UCL Medical School, London, United Kingdom
Transplantation 87:852-6. 2009..Epstein-Barr virus (EBV) is associated with posttransplant lymphoproliferative disease. We monitored the incidence of EBV viraemia in adult renal transplant recipients and investigated the association with clinical parameters...