Colette Smith

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study
    David A Kamara
    Research Dept, of Infection and Population Health, University College London, London, United Kingdom
    BMC Nephrol 15:51. 2014
  2. pmc Higher risk of renal impairment associated with tenofovir use amongst people living with HIV in India: a comparative cohort analysis between Western India and United Kingdom
    Sanjay N Pujari
    Institute of Infectious Diseases, Pune, India
    BMC Infect Dis 14:173. 2014
  3. doi request reprint Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration
    Colette J Smith
    Research Department of Infection and Population Health, University College London, London, UK Electronic address
    Lancet 384:241-8. 2014
  4. doi request reprint Factors associated with specific causes of death amongst HIV-positive individuals in the D:A:D Study
    Colette Smith
    Research Department of Infection and Population Health, UCL, Royal Free Campus, London, UK
    AIDS 24:1537-48. 2010
  5. doi request reprint Estimated average annual rate of change of CD4(+) T-cell counts in patients on combination antiretroviral therapy
    Amanda Mocroft
    Research Department of Infection and Population Health, University College London Medical School, London, UK
    Antivir Ther 15:563-70. 2010
  6. doi request reprint Outcomes in the first year after initiation of first-line HAART among heterosexual men and women in the UK CHIC Study
    Tristan J Barber
    St Stephen s AIDS Trust Clinical Trials Unit, Chelsea and Westminster NHS Foundation Trust, London, UK
    Antivir Ther 16:805-14. 2011
  7. doi request reprint Data linkage reduces loss to follow-up in an observational HIV cohort study
    Teresa Hill
    Research Department of Infection and Population Health, UCL Medical School, London, UK
    J Clin Epidemiol 63:1101-9. 2010
  8. doi request reprint Discordant responses on starting highly active antiretroviral therapy: suboptimal CD4 increases despite early viral suppression in the UK Collaborative HIV Cohort (UK CHIC) Study
    R J C Gilson
    Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, University College London, The Mortimer Market Centre, Camden Primary Care Trust, London, UK
    HIV Med 11:152-60. 2010
  9. ncbi request reprint Determinants of virological failure after successful viral load suppression in first-line highly active antiretroviral therapy
    Anna M Geretti
    Royal Free and University College Medical School, London, UK
    Antivir Ther 13:927-36. 2008
  10. doi request reprint The impact of HIV drug resistance testing on changes to treatment
    Loveleen Bansi
    Research Department of Infection and Population Health, UCL Medical School, UK
    AIDS 25:603-10. 2011

Detail Information

Publications33

  1. pmc Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study
    David A Kamara
    Research Dept, of Infection and Population Health, University College London, London, United Kingdom
    BMC Nephrol 15:51. 2014
    ..73 m2 (using Cockcroft Gault) in the Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) study from 2004 to 2011...
  2. pmc Higher risk of renal impairment associated with tenofovir use amongst people living with HIV in India: a comparative cohort analysis between Western India and United Kingdom
    Sanjay N Pujari
    Institute of Infectious Diseases, Pune, India
    BMC Infect Dis 14:173. 2014
    ....
  3. doi request reprint Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration
    Colette J Smith
    Research Department of Infection and Population Health, University College London, London, UK Electronic address
    Lancet 384:241-8. 2014
    ..Consequently, the relative importance of other traditionally non-AIDS-related morbidities has increased. We investigated trends over time in all-cause mortality and for specific causes of death in people with HIV from 1999 to 2011...
  4. doi request reprint Factors associated with specific causes of death amongst HIV-positive individuals in the D:A:D Study
    Colette Smith
    Research Department of Infection and Population Health, UCL, Royal Free Campus, London, UK
    AIDS 24:1537-48. 2010
    ..To investigate any emerging trends in causes of death amongst HIV-positive individuals in the current cART era, and to investigate the factors associated with each specific cause of death...
  5. doi request reprint Estimated average annual rate of change of CD4(+) T-cell counts in patients on combination antiretroviral therapy
    Amanda Mocroft
    Research Department of Infection and Population Health, University College London Medical School, London, UK
    Antivir Ther 15:563-70. 2010
    ..Patients receiving combination antiretroviral therapy (cART) might continue treatment with a virologically failing regimen. We sought to identify annual change in CD4(+) T-cell count according to levels of viraemia in patients on cART...
  6. doi request reprint Outcomes in the first year after initiation of first-line HAART among heterosexual men and women in the UK CHIC Study
    Tristan J Barber
    St Stephen s AIDS Trust Clinical Trials Unit, Chelsea and Westminster NHS Foundation Trust, London, UK
    Antivir Ther 16:805-14. 2011
    ..We analysed the influence of gender on use and outcomes of first-line HAART in a UK cohort...
  7. doi request reprint Data linkage reduces loss to follow-up in an observational HIV cohort study
    Teresa Hill
    Research Department of Infection and Population Health, UCL Medical School, London, UK
    J Clin Epidemiol 63:1101-9. 2010
    ..To ascertain the degree of loss to follow-up in a cohort and to identify its predictors...
  8. doi request reprint Discordant responses on starting highly active antiretroviral therapy: suboptimal CD4 increases despite early viral suppression in the UK Collaborative HIV Cohort (UK CHIC) Study
    R J C Gilson
    Centre for Sexual Health and HIV Research, Research Department of Infection and Population Health, University College London, The Mortimer Market Centre, Camden Primary Care Trust, London, UK
    HIV Med 11:152-60. 2010
    ..This study was designed to determine the incidence of a discordant response at two time-points, soon after 6 months and at 12 months, and to determine the relationship with clinical outcomes...
  9. ncbi request reprint Determinants of virological failure after successful viral load suppression in first-line highly active antiretroviral therapy
    Anna M Geretti
    Royal Free and University College Medical School, London, UK
    Antivir Ther 13:927-36. 2008
    ....
  10. doi request reprint The impact of HIV drug resistance testing on changes to treatment
    Loveleen Bansi
    Research Department of Infection and Population Health, UCL Medical School, UK
    AIDS 25:603-10. 2011
    ..We investigate changes made to therapy after a resistance test result and identify factors associated with switching regimen...
  11. pmc Lack of association between use of efavirenz and death from suicide: evidence from the D:A:D study
    Colette Smith
    Infection and Population Health, University College London, London, UK
    J Int AIDS Soc 17:19512. 2014
    ..We investigated the association between EFV use and completed suicide...
  12. ncbi request reprint Predictors and kinetics of occult hepatitis B virus infection in HIV-infected persons
    Gaia Nebbia
    Department of Virology, Royal Free Hospital and Royal Free and University College Medical School, London, UK
    J Med Virol 79:1464-71. 2007
    ..The intermittent nature of HBV-DNA detection poses a diagnostic challenge, but no association is observed with ALT levels...
  13. doi request reprint Development and Validation of a Risk Score for Chronic Kidney Disease in HIV Infection Using Prospective Cohort Data from the D:A:D Study
    Amanda Mocroft
    Department of Infection and Population Health, University College London, London, United Kingdom
    PLoS Med 12:e1001809. 2015
    ..The aims of this study were to develop a simple, externally validated, and widely applicable long-term risk score model for CKD in HIV-positive individuals that can guide decision making in clinical practice...
  14. pmc A clinically useful risk-score for chronic kidney disease in HIV infection
    Amanda Mocroft
    Department of Infection and Population Health, University College London, London, UK
    J Int AIDS Soc 17:19514. 2014
    ..Development of a simple, widely applicable risk score for chronic kidney disease (CKD) allows comparisons of risks or benefits of starting potentially nephrotoxic antiretrovirals (ARVs) as part of a treatment regimen...
  15. pmc Sexual behaviour, recreational drug use and hepatitis C co-infection in HIV-diagnosed men who have sex with men in the United Kingdom: results from the ASTRA study
    Marina Daskalopoulou
    University College London Royal Free Hospital, London, UK
    J Int AIDS Soc 17:19630. 2014
    ..We explore associations between self-reported sexual behaviours and drug use with cumulative HCV prevalence, as well as new HCV diagnosis...
  16. doi request reprint The effect of transmitted HIV-1 drug resistance on pre-therapy viral load
    Linda Harrison
    HIV and Infections Group, MRC Clinical Trials Unit, London, UK
    AIDS 24:1917-22. 2010
    ..Reduced replication capacity of viruses expressing drug resistant mutations implies that patients with transmitted drug resistance (TDR) could have lower HIV RNA viral load than those infected with wild-type virus...
  17. doi request reprint Predictors of advanced chronic kidney disease and end-stage renal disease in HIV-positive persons
    Lene Ryom
    aCopenhagen HIV Programme, University of Copenhagen, Faculty of Health and Medical Sciences and Epidemiklinikken M5132, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark bResearch Department of Infection and Population Health, UCL, London, UK cDivision of Nephrology, Mount Sinai School of Medicine, New York, USA dAcademic Medical Center, University of Amsterdam, and Stichting HIV Monitoring, The Netherlands eClinic for Infectious Diseases and Hospital Hygiene, Kantonsspital Aarau, Switzerland fService de médecine interne et maladies infectieuses, Hôpital Saint André, CHU de Bordeaux gNephrology Department, Public Health Department, CHU Nice, France hICAP Columbia University and Harlem Hospital, New York, USA iKirby Institute, Sydney, Australia
    AIDS 28:187-99. 2014
    ..Whilst several antiretroviral drugs have been associated with moderate chronic kidney disease (CKD), their contribution to advanced CKD and end-stage renal disease (ESRD) remain unknown...
  18. doi request reprint Responses to switching to maraviroc-based antiretroviral therapy in treated patients with suppressed plasma HIV-1-RNA load
    Paola Vitiello
    UCL Medical School, London, UK
    Intervirology 55:172-8. 2012
    ..The aim of this study was to evaluate patients on suppressive ART switching to an MVC-containing regimen (MVC-CR), and test the hypothesis that the switch may have an impact on T cell activation...
  19. pmc Factors influencing lopinavir and atazanavir plasma concentration
    Wolfgang Stöhr
    MRC Clinical Trials Unit, London, UK
    J Antimicrob Chemother 65:129-37. 2010
    ..The aim of this study was to evaluate which demographic factors and concomitant drugs are associated with lopinavir and atazanavir plasma concentration...
  20. pmc Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial
    Paul D Griffiths
    Centre for Virology, UCL Medical School, London, UK
    Lancet 377:1256-63. 2011
    ..Values of viral load correlate with development of end-organ disease and are moderated by pre-existing natural immunity. Our aim was to determine whether vaccine-induced immunity could do likewise...
  21. doi request reprint Late diagnosis in the HAART era: proposed common definitions and associations with mortality
    Caroline A Sabin
    Research Department of Infection and Population Health, UCL Medical School, London, UK
    AIDS 24:723-7. 2010
    ....
  22. pmc Socio-economic factors and virological suppression among people diagnosed with HIV in the United Kingdom: results from the ASTRA study
    Lisa Burch
    Department of Infection and Population Health, University College London, London, UK
    J Int AIDS Soc 17:19533. 2014
    ..The impact of socio-economic factors on virological suppression has been little studied...
  23. pmc Rate of viral load failure over time in people on ART in the UK Collaborative HIV Cohort (CHIC) study
    Jemma O'Connor
    Department of Infection and Population Health, UCL, London, UK
    J Int AIDS Soc 17:19527. 2014
    ..It is unclear whether those who have maintained VL suppression for several years will be able to continue to do so, or if rates of VL failure - due to poor adherence, ART interruption and/or resistance - remain at appreciable levels...
  24. doi request reprint Characteristics of Epstein-Barr viraemia in adult liver transplant patients: a retrospective cohort study
    Neil Halliday
    Department of Virology, Royal Free London NHS Foundation Trust, London, UK
    Transpl Int 27:838-46. 2014
    ..001) but shortened with ganciclovir exposure (P = 0.06). Younger patients were more likely to have high peak viral loads (P = 0.07). No clinical signs or symptoms or adverse outcomes were associated with EBV reactivation. ..
  25. doi request reprint Clinical epidemiology of HIV-associated end-stage renal failure in the UK
    Loveleen Bansi
    University College London Medical School, London, UK
    AIDS 23:2517-21. 2009
    ..To describe the clinical epidemiology of HIV-associated end-stage renal failure (HIV/ESRF) from 1998 to 2007 in the United Kingdom...
  26. doi request reprint The associations between age and the development of laboratory abnormalities and treatment discontinuation for reasons other than virological failure in the first year of highly active antiretroviral therapy
    C A Sabin
    Department of Primary Care and Population Science, Royal Free and UC Medical School, London, UK
    HIV Med 10:35-43. 2009
    ....
  27. ncbi request reprint Acetyl-l-carnitine: a pathogenesis based treatment for HIV-associated antiretroviral toxic neuropathy
    Andrew M Hart
    Blond McIndoe Centre, Royal Free and University College Medical School, London, UK
    AIDS 18:1549-60. 2004
    ..ALCAR enhances neurotrophic support of sensory neurons and promotes energy metabolism, potentially causing nerve regeneration and symptom relief...
  28. doi request reprint Will antiretroviral therapy reduce HIV-related liver risk?
    Joanna Allen
    aDepartment of Infectious Diseases and HIV Medicine bResearch Department of Infection and Population Health, UCL, Royal Free Campus, London, United Kingdom
    Curr Opin HIV AIDS 9:48-53. 2014
    ..This article reviews the positive and potential negative impact of cART on liver-related morbidity and mortality...
  29. doi request reprint Impact of UK academic foundation programmes on aspirations to pursue a career in academia
    Oliver T A Lyons
    Academic Department of Surgery, St Thomas Hospital, London, UK
    Med Educ 44:996-1005. 2010
    ..This study aimed to determine the role played by academic foundation programmes in influencing junior doctors' desire to pursue a career in academic medicine...
  30. pmc Smoking and life expectancy among HIV-infected individuals on antiretroviral therapy in Europe and North America
    Marie Helleberg
    aDepartment of Infectious Diseases, Copenhagen University Hospital, Rigshospitalet bFaculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark cSchool of Social and Community Medicine, University of Bristol, Bristol, UK dUniversité Bordeaux, ISPED, Centre INSERM U897 Epidemiologie Biostatistique, Bordeaux, France eDepartment of Global Health, Academisch Medisch Centrum bij de universiteit van Amsterdam, and Stichting HIV Monitoring, Amsterdam, The Netherlands fDepartment of Internal Medicine, University of Cologne and German Centre for Infection Research DZIF, Cologne, Germany gSorbonne Universités, UPMC Univ Paris 06 hINSERM, UMR_S 1136, Institut Pierre Louis d Epidémiologie et de Santé Publique, Paris, France iClinic of Infectious Diseases and Tropical Medicine, San Paolo Hospital, University of Milan, Milan, Italy jService des maladies infectieuses, CHUV, Lausanne, Switzerland kResearch Department of Infection and Population Health, University College London, London, UK lYale University, New Haven mVA Connecticut Healthcare System, West Haven, Connecticut, USA nDivision of Infectious Diseases, University of Calgary, Calgary, USA
    AIDS 29:221-9. 2015
    ..Cardiovascular disease and non-AIDS malignancies have become major causes of death among HIV-infected individuals. The relative impact of lifestyle and HIV-related factors are debated...
  31. doi request reprint Fibroblast growth factor 23 and soluble klotho in children with chronic kidney disease
    Mandy Wan
    Renal Unit, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK
    Nephrol Dial Transplant 28:153-61. 2013
    ..There are scarce data on the levels of its essential co-receptor klotho, and longitudinal changes in FGF23 levels are also unknown...
  32. ncbi request reprint Reconstitution of herpes simplex virus-specific T cell immunity in HIV-infected patients receiving highly active antiretroviral therapy
    Meghna Ramaswamy
    Department of Virology, Royal Free Hospital and Royal Free and University College Medical School, North Middlesex University Hospital, London, UK
    J Infect Dis 195:410-5. 2007
    ..6/month (95% confidence interval, 1.2-9.9 [P=.01]) and 21.3/100 CD4 cells/mm(3) gained (95% confidence interval, 13.8-28.7 [P<.0001]). Responses were correlated with LTNP status and CD4 cell count...
  33. doi request reprint Prospective monitoring of Epstein-Barr virus DNA in adult renal transplant recipients during the early posttransplant period: role of mycophenolate mofetil
    Michael V Holmes
    Centre for Virology, Royal Free Campus, UCL Medical School, London, United Kingdom
    Transplantation 87:852-6. 2009
    ..Epstein-Barr virus (EBV) is associated with posttransplant lymphoproliferative disease. We monitored the incidence of EBV viraemia in adult renal transplant recipients and investigated the association with clinical parameters...