Research Topics
Genomes and GenesSpecies | Maya Sieber-BlumSummaryAffiliation: University of Newcastle Country: UK Publications
| Collaborators
|
Detail Information
Publications
Epidermal neural crest stem cell (EPI-NCSC)--mediated recovery of sensory function in a mouse model of spinal cord injuryYao Fei Hu
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Stem Cell Rev 6:186-98. 2010..EPI-NCSC are uniquely qualified for cell-based therapy in spinal cord injury, as neural crest cells and neural tube stem cells share a higher order stem cell and are thus ontologically closely related...- Epidermal stem cell dynamicsMaya Sieber-Blum
Institute of Genetic Medicine and Northeast England Stem Cell Institute, Newcastle University, Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, UK
Stem Cell Res Ther 2:29. 2011..While this is a provocative result and the authors' conclusion may well be correct, there are alternative explanations... 
Epidermal neural crest stem cells and their use in mouse models of spinal cord injuryMaya Sieber-Blum
Institute of Human Genetics and North East England Stem Cell Institute, Newcastle University, Centre for Life, Newcastle upon Tyne, UK
Brain Res Bull 83:189-93. 2010..Intraspinal EPI-NCSC thus have multiple effects in the contused spinal cord, the sum of which can explain the observed functional improvements...- Epidermal neural crest stem cells (EPI-NCSC) and pluripotencyMaya Sieber-Blum
Institute of Human Genetics and North East England Stem Cell Institute, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE13BZ, UK
Stem Cell Rev 4:256-60. 2008..Since the patients' own EPI-NCSC could be used for autologous transplantation, this would avoid graft rejection... 
Characterization of epidermal neural crest stem cell (EPI-NCSC) grafts in the lesioned spinal cordMaya Sieber-Blum
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Mol Cell Neurosci 32:67-81. 2006..Collectively, our data indicate that intraspinal EPI-NCSC demonstrate several desirable characteristics that may include local neural replacement and re-myelination...- Neurotrophin-3 signaling in mammalian Merkel cell developmentViktor Szeder
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Dev Dyn 228:623-9. 2003..These results show that NT-3 signaling is not required for the differentiation of Merkel cells, but that it is essential for their postnatal survival... - Neural crest origin of mammalian Merkel cellsViktor Szeder
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Dev Biol 253:258-63. 2003..Merkel cells in whiskers and interfollicular locations express the transgene, beta-galactosidase, identifying them as neural crest descendants. We thus conclude that murine Merkel cells originate from the neural crest... - Ontogeny and plasticity of adult hippocampal neural stem cellsMaya Sieber-Blum
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisc 53226, USA
Dev Neurosci 25:273-8. 2003..Furthermore, they show plasticity and a remarkably wide range of developmental options of adult hippocampal stem cells... - Norepinephrine transport-mediated gene expression in noradrenergic neurogenesisYao Fei Hu
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
BMC Genomics 10:151. 2009..While the structure of NET und the regulation of NET function are well described, little is known about downstream target genes of norepinephrine (NE) transport... - An epidermal neural crest stem cell (EPI-NCSC) molecular signatureYao Fei Hu
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
Stem Cells 24:2692-702. 2006..Multipotent adult mammalian stem cells are of great interest because of their potential value in future cell replacement therapy by autologous transplantation, which avoids graft rejection... - The adult hair follicle: cradle for pluripotent neural crest stem cellsMaya Sieber-Blum
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee 53226, USA
Birth Defects Res C Embryo Today 72:162-72. 2004..The intrinsic high degree of plasticity of eNCSCs and the fact that they are easily accessible in the skin make them attractive candidates for diverse autologous cell therapy strategies... - The role of NT-3 signaling in Merkel cell developmentMaya Sieber-Blum
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Prog Brain Res 146:63-72. 2004.... - Essential role of stem cell factor signaling in primary sensory neuron developmentZhi Jian Zhang
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, USA
Dev Neurosci 31:202-11. 2009..We thus conclude that, in the absence of SCF signaling, neural crest-derived progenitors do not differentiate into c-kit-expressing visceral and somatic afferent neurons... - Human epidermal neural crest stem cells (hEPI-NCSC)--characterization and directed differentiation into osteocytes and melanocytesOliver Clewes
Institute of Genetic Medicine, and North East England Stem Cell Institute, Centre for Life, Newcastle University, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK
Stem Cell Rev 7:799-814. 2011..As somatic stem cells, hEPI-NCSC are conducive to autologous transplantation, which avoids graft rejection. Together, these traits make hEPI-NCSC novel and attractive candidates for future cell-based therapies and regenerative medicine... - Cardiac neural crest stem cellsMaya Sieber-Blum
Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Anat Rec A Discov Mol Cell Evol Biol 276:34-42. 2004..Surprisingly, many diverse nonneuronal embryonic tissues, in particular in the cardiovascular system, express NET also. It will be of interest to determine whether norepinephrine transport plays a role also in cardiovascular development... - Diffusion heterogeneity tensor MRI (?-Dti): mathematics and initial applications in spinal cord regeneration after trauma - biomed 2009Benjamin M Ellington
Medical College of Wisconsin, Milwaukee, WI
Biomed Sci Instrum 45:167-72. 2009..This study develops the mathematics of this new technique along with an initial application in quantifying spinal cord regeneration following acute injection of epidermal neural crest stem cell (EPI-NCSC) grafts...