Sebastian M Shimeld

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint Urochordate betagamma-crystallin and the evolutionary origin of the vertebrate eye lens
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, The Tinbergen Building, South Parks Road, Oxford OX1 3PS, United Kingdom
    Curr Biol 15:1684-9. 2005
  2. doi request reprint Evolutionary crossroads in developmental biology: cyclostomes (lamprey and hagfish)
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, The Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK
    Development 139:2091-9. 2012
  3. doi request reprint Genomic Sequence and Experimental Tractability of a New Decapod Shrimp Model, Neocaridina denticulata
    Nathan J Kenny
    School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Mar Drugs 12:1419-37. 2014
  4. pmc An EST screen from the annelid Pomatoceros lamarckii reveals patterns of gene loss and gain in animals
    Tokiharu Takahashi
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, UK
    BMC Evol Biol 9:240. 2009
  5. pmc Muscle differentiation in a colonial ascidian: organisation, gene expression and evolutionary considerations
    Valentina Degasperi
    Dipartimento di Biologia, Universita degli Studi di Padova, Via Ugo Bassi 58 B, 35131, Padova, Italy
    BMC Dev Biol 9:48. 2009
  6. ncbi request reprint Evidence for the regulation of left-right asymmetry in Ciona intestinalis by ion flux
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    Dev Dyn 235:1543-53. 2006
  7. pmc An amphioxus Gli gene reveals conservation of midline patterning and the evolution of hedgehog signalling diversity in chordates
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS ONE 2:e864. 2007
  8. ncbi request reprint Peter Holland, homeobox genes and the developmental basis of animal diversity
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, Oxford, UK
    Int J Dev Biol 52:3-7. 2008
  9. doi request reprint C2H2 zinc finger genes of the Gli, Zic, KLF, SP, Wilms' tumour, Huckebein, Snail, Ovo, Spalt, Odd, Blimp-1, Fez and related gene families from Branchiostoma floridae
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Dev Genes Evol 218:639-49. 2008
  10. doi request reprint Evolutionary genomics of the Fox genes: origin of gene families and the ancestry of gene clusters
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, Oxford, UK
    Genomics 95:256-60. 2010

Collaborators

Detail Information

Publications38

  1. ncbi request reprint Urochordate betagamma-crystallin and the evolutionary origin of the vertebrate eye lens
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, The Tinbergen Building, South Parks Road, Oxford OX1 3PS, United Kingdom
    Curr Biol 15:1684-9. 2005
    ....
  2. doi request reprint Evolutionary crossroads in developmental biology: cyclostomes (lamprey and hagfish)
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, The Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK
    Development 139:2091-9. 2012
    ..We then discuss how studies of cyclostomes have provided important insight into the evolution of fins, jaws, skeleton and neural crest...
  3. doi request reprint Genomic Sequence and Experimental Tractability of a New Decapod Shrimp Model, Neocaridina denticulata
    Nathan J Kenny
    School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Mar Drugs 12:1419-37. 2014
    ....
  4. pmc An EST screen from the annelid Pomatoceros lamarckii reveals patterns of gene loss and gain in animals
    Tokiharu Takahashi
    Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, UK
    BMC Evol Biol 9:240. 2009
    ..Increasing efforts have been put towards redressing this imbalance in recent years, and one of the principal phyla in the vanguard of this endeavour is the Annelida...
  5. pmc Muscle differentiation in a colonial ascidian: organisation, gene expression and evolutionary considerations
    Valentina Degasperi
    Dipartimento di Biologia, Universita degli Studi di Padova, Via Ugo Bassi 58 B, 35131, Padova, Italy
    BMC Dev Biol 9:48. 2009
    ..Several ascidian species form colonies of clonal individuals by asexual reproduction. During their life cycle, ascidians present three muscle types: striated in larval tail, striated in the heart, and unstriated in the adult body-wall...
  6. ncbi request reprint Evidence for the regulation of left-right asymmetry in Ciona intestinalis by ion flux
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    Dev Dyn 235:1543-53. 2006
    ..These experiments demonstrate a role for ion flux in the regulation of asymmetry in Ciona, and show a conserved, ancestral role for the H(+)K(+)ATPase ion pump in this process...
  7. pmc An amphioxus Gli gene reveals conservation of midline patterning and the evolution of hedgehog signalling diversity in chordates
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS ONE 2:e864. 2007
    ..Amphioxus is one of the closest living relatives of the vertebrates, having split from the vertebrate lineage prior to the widespread gene duplication prominent in early vertebrate evolution...
  8. ncbi request reprint Peter Holland, homeobox genes and the developmental basis of animal diversity
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, Oxford, UK
    Int J Dev Biol 52:3-7. 2008
    ..Here, I profile Peter Holland's contribution to the rebirth of Evolutionary Developmental Biology in general and the study of homeobox genes and vertebrate origins in particular...
  9. doi request reprint C2H2 zinc finger genes of the Gli, Zic, KLF, SP, Wilms' tumour, Huckebein, Snail, Ovo, Spalt, Odd, Blimp-1, Fez and related gene families from Branchiostoma floridae
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Dev Genes Evol 218:639-49. 2008
    ..floridae C2H2 zinc finger genes, representing at least 15 gene families. For 17 of these genes, expressed sequence tag clusters and associated clone identification codes relating to the B. floridae gene collection are given...
  10. doi request reprint Evolutionary genomics of the Fox genes: origin of gene families and the ancestry of gene clusters
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, Oxford, UK
    Genomics 95:256-60. 2010
    ..Ancient linkages between genes are a prominent feature of the Fox genes, depicting a history of gene clusters, some of which may be relevant to understanding Fox gene function...
  11. doi request reprint Clustered Fox genes in lophotrochozoans and the evolution of the bilaterian Fox gene cluster
    Sebastian M Shimeld
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Dev Biol 340:234-48. 2010
    ..This demonstrates conservation of genomic organisation and expression of these genes can be traced in all three bilaterian Superphyla. These data are evaluated against competing theories for the long-term maintenance of gene clusters...
  12. doi request reprint Analysis of lamprey clustered Fox genes: insight into Fox gene evolution and expression in vertebrates
    Karl R Wotton
    Department of Zoology, University of Oxford, The Tinbergen Building, South Parks Road, Oxford, OX1 3PS, UK
    Gene 489:30-40. 2011
    ..We interpret our results through a chordate-wide comparison of expression patterns and discuss gene content in the context of theories on the evolution of the vertebrate genome...
  13. doi request reprint Expression of FoxC, FoxF, FoxL1, and FoxQ1 genes in the dogfish Scyliorhinus canicula defines ancient and derived roles for Fox genes in vertebrate development
    Karl R Wotton
    Department of Zoology, University of Oxford, The Tinbergen Building, South Parks Road, Oxford, United Kingdom
    Dev Dyn 237:1590-603. 2008
    ..Comparison to invertebrate chordates shows that the majority of conserved vertebrate expression domains mark tissues that are part of the primitive chordate body plan...
  14. pmc Comparative genomics of vertebrate Fox cluster loci
    Karl R Wotton
    Department of Zoology, University of Oxford, The Tinbergen Building, South Parks Road, Oxford, OX1 3PS, UK
    BMC Genomics 7:271. 2006
    ..However in contrast to the Hox genes, only two clusters of paralogous Fox genes have so far been identified in the Human genome and the organisation in other vertebrates is unknown...
  15. doi request reprint Additive multiple k-mer transcriptome of the keelworm Pomatoceros lamarckii (Annelida; Serpulidae) reveals annelid trochophore transcription factor cassette
    Nathan J Kenny
    Department of Zoology, University of Oxford, Oxford, UK
    Dev Genes Evol 222:325-39. 2012
    ..Our study illustrates the utility of such transcriptomic assembly methods as a gene discovery tool and greatly expands our knowledge of transcription factor genes in annelids in general and in this species in particular...
  16. ncbi request reprint Chordate betagamma-crystallins and the evolutionary developmental biology of the vertebrate lens
    Kumars Riyahi
    Department of Zoology, University of Oxford, Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK
    Comp Biochem Physiol B Biochem Mol Biol 147:347-57. 2007
    ....
  17. ncbi request reprint The developmental expression of foxl2 in the dogfish Scyliorhinus canicula
    Karl R Wotton
    Department of Zoology, University of Oxford, The Tinbergen Building, South Parks Road, Oxford OX1 3PS, UK
    Gene Expr Patterns 7:793-7. 2007
    ..Thus, S. canicula foxl2 is a marker for the mandibular mesoderm and gill buds and its expression is conserved in the perioptic mesenchyme, developing eyelids and pituitary...
  18. doi request reprint A genome-wide view of transcription factor gene diversity in chordate evolution: less gene loss in amphioxus?
    Jordi Paps
    Department of Zoology, University of Oxford, UK
    Brief Funct Genomics 11:177-86. 2012
    ..We conclude that, at least in terms of transcription factor gene complexity, the genome of amphioxus has experienced remarkable stasis compared to the genomes of other chordates...
  19. doi request reprint Analysis of a deep transcriptome from the mantle tissue of Patella vulgata Linnaeus (Mollusca: Gastropoda: Patellidae) reveals candidate biomineralising genes
    Gijsbert D A Werner
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Mar Biotechnol (NY) 15:230-43. 2013
    ..We conclude that de novo assembly of Illumina data offers a cheap and rapid route to a predicted transcriptome that can be used as a resource for further biological study...
  20. doi request reprint The formation and positioning of cilia in Ciona intestinalis embryos in relation to the generation and evolution of chordate left-right asymmetry
    Helen Thompson
    Department of Zoology, University of Oxford, Oxford, UK
    Dev Biol 364:214-23. 2012
    ..intestinalis left-right asymmetry but that this would have to be in a sensory capacity, perhaps as mechanosensors as hypothesised in two-cilia physical models of vertebrate cilia-driven asymmetry...
  21. ncbi request reprint The evolution of left-right asymmetry in chordates
    Clive J Boorman
    School of Animal and Microbial Sciences, The University of Reading, Whiteknights, UK
    Bioessays 24:1004-11. 2002
    ..These studies suggest that left-right asymmetry in all chordates is regulated by a conserved developmental pathway, and that this pathway evolved before the separation of the lineages leading to living chordates...
  22. ncbi request reprint Pitx homeobox genes in Ciona and amphioxus show left-right asymmetry is a conserved chordate character and define the ascidian adenohypophysis
    Clive J Boorman
    School of Animal and Microbial Sciences, University of Reading, Whiteknights, UK
    Evol Dev 4:354-65. 2002
    ..This shows that asymmetrical Pitx gene expression, and by inference directional asymmetry, evolved before the radiation of living chordates and should be considered a chordate character...
  23. ncbi request reprint Cloning and expression of a Pitx homeobox gene from the lamprey, a jawless vertebrate
    Clive J Boorman
    School of Animal and Microbial Sciences, The University of Reading, Whiteknights, UK
    Dev Genes Evol 212:349-53. 2002
    ..These results show some key aspects of Pitx gene expression in gnathostomes are primitive for all living vertebrates...
  24. ncbi request reprint Molecular evidence from Ciona intestinalis for the evolutionary origin of vertebrate sensory placodes
    Francoise Mazet
    School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, UK
    Dev Biol 282:494-508. 2005
    ....
  25. pmc Evolution of developmental mechanisms
    David E K Ferrier
    School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, UK
    Genome Biol 3:REPORTS4020. 2002
    ..A report on the joint Spring meeting of the British Society of Developmental Biology and the Genetics Society, York, UK, 20-23 March 2002...
  26. ncbi request reprint Protochordate Zic genes define primitive somite compartments and highlight molecular changes underlying neural crest evolution
    Neil J Gostling
    School of Animal and Microbial Sciences, University of Reading, P O Box 228, Whiteknights, Reading RG6 6AJ, United Kingdom
    Evol Dev 5:136-44. 2003
    ..Based on these observations we suggest that a change in Zic regulation, specifically the evolution of a dorsal neural expression domain in vertebrate neurulae, was an important step in the evolution of the neural crest...
  27. ncbi request reprint Gene duplication and divergence in the early evolution of vertebrates
    Francoise Mazet
    School of Animal and Microbial Sciences, University of Reading, Whiteknights, UK
    Curr Opin Genet Dev 12:393-6. 2002
    ..These principles may be then extrapolated to understanding the early evolution of the vertebrates...
  28. ncbi request reprint Characterisation of an amphioxus Fringe gene and the evolution of the vertebrate segmentation clock
    Francoise Mazet
    School of Animal and Microbial Sciences, The University of Reading, Whiteknights, PO Box 228, Reading RG6 6AJ, UK
    Dev Genes Evol 213:505-9. 2003
    ..No AmphiFringe transcripts were detected in the mesoderm. Based on these observations, we propose a model depicting a successive recruitment of Fringe in the maintenance then regulation of segmentation during vertebrate evolution...
  29. ncbi request reprint Molecular evidence from ascidians for the evolutionary origin of vertebrate cranial sensory placodes
    Francoise Mazet
    School of Animal and Microbial Sciences, University of Reading, UK
    J Exp Zool B Mol Dev Evol 304:340-6. 2005
    ..Our interpretation of these findings is that vertebrate placodes and sea squirt siphon primordia have evolved from the same patches of specialised ectoderm present in the common ancestor of the chordates...
  30. ncbi request reprint Expression of AmphiCoe, an amphioxus COE/EBF gene, in the developing central nervous system and epidermal sensory neurons
    Francoise Mazet
    School of Animal and Microbial Sciences, The University of Reading, Whiteknights, Reading, UK
    Genesis 38:58-65. 2004
    ....
  31. ncbi request reprint Phylogenetic relationships of the Fox (Forkhead) gene family in the Bilateria
    Francoise Mazet
    School of Animal and Microbial Sciences, The University of Reading, P O Box 228 Whiteknights, RG6 6AJ Reading, UK
    Gene 316:79-89. 2003
    ..Our analyses suggest that the common ancestor of protostomes and deuterostomes had a minimum complement of 14 Fox genes...
  32. ncbi request reprint Pax gene expression in the developing central nervous system of Ciona intestinalis
    Francoise Mazet
    School of Animal and Microbial Sciences, The University of Reading, P O Box 228, Whiteknights, RG6 6AJ, Reading, UK
    Gene Expr Patterns 3:743-5. 2003
    ..The overlap between CiPax3/7 and CiPax2/5/8 is unlike that described in the ascidian Halocynthia rorezti...
  33. doi request reprint Genesis and expansion of metazoan transcription factor gene classes
    Claire Larroux
    School of Integrative Biology, The University of Queensland, Brisbane, Queensland, Australia
    Mol Biol Evol 25:980-96. 2008
    ..Transcription factor orthologues present in sponge, cnidarian, and bilaterian genomes may represent part of the core metazoan regulatory network underlying the origin of animal development and multicellularity...
  34. ncbi request reprint An ancient Fox gene cluster in bilaterian animals
    Francoise Mazet
    Curr Biol 16:R314-6. 2006
  35. ncbi request reprint Calcium turns sinister in left-right asymmetry
    Sebastian M Shimeld
    School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, UK
    Trends Genet 20:277-80. 2004
  36. ncbi request reprint The amphioxus FoxQ1 gene is expressed in the developing endostyle
    Francoise Mazet
    School of Animal and Microbial Sciences, University of Reading, Whiteknights, Reading RG6 6AJ, UK
    Gene Expr Patterns 5:313-5. 2005
    ..Ci-FoxQ1 is also expressed in the endostyle, highlighting this as a conserved site of FoxQ1 gene expression in basal chordates...
  37. ncbi request reprint The evolution of chordate neural segmentation
    Francoise Mazet
    School of Animal and Microbial Sciences, The University of Reading, P O Box 228, Whiteknights, Reading, RG6 6AJ, United Kingdom
    Dev Biol 251:258-70. 2002
    ..A consequence of this would have been that segmentation of vertebrate head mesoderm would no longer have been required, paving the way for the evolution of the unsegmented head mesoderm seen in living vertebrates...
  38. ncbi request reprint A genomewide survey of developmentally relevant genes in Ciona intestinalis. III. Genes for Fox, ETS, nuclear receptors and NFkappaB
    Kasumi Yagi
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Dev Genes Evol 213:235-44. 2003
    ..The present results therefore provide molecular information for the investigation of complex developmental processes, and an insight into chordate evolution...