M Sharpe

..We aimed to assess the efficacy and cost of a nurse-delivered complex intervention that was designed to treat major depressive disorder in patients who have cancer...

..We therefore aimed to determine predictors of poor subjective outcome for new neurology out-patients with symptoms unexplained by disease 1 year after the initial consultation...

..We aimed to determine how frequently this misdiagnosis occurs, and whether it has become less common since the widespread availability of brain imaging...

..Secondary outcomes include severity of anxiety, pain and fatigue; self-rated improvement of depression; quality of life and satisfaction with depression care. TRIAL REGISTRATION: Current controlled trials ISRCTN75905964...

..2) Depression Care for People with Cancer as a supplement to usual care will cost more than usual care alone but will be more cost effective in achieving improvements in patients' depression and quality of life...

..CONCLUSION: Patients with CFS show evidence of reduced complexity of activity patterns. Measures of complexity applied to activity have potential value as objective indicators for CFS...

..Specialist medical care is commonly provided but its efficacy when given alone is not established. This trial compares the efficacy of the additional therapies when added to specialist medical care against specialist medical care alone...

..Given the increasing use of Rasch models in health research the purpose of this study was therefore to explore the relationship between fit statistics and sample size for polytomous data...

..We aimed to investigate the ways patients with MUS and their General Practitioners (GPs) interpret low mood and worry, whether they regard them as depressive or anxiety disorders and how they relate them causally to symptoms...

..At the final 6-month outcome, 38.5% (95% CI, 5.4-57%) fewer patients in the intervention group still met the criteria for MDD...

..Very few had received psychological treatment or had been referred to mental health services. Most were receiving no potentially effective therapy...

..As a guide to management it raises as many questions as it answers. Much remains to be resolved before guidance that is both evidence based and acceptable to all parties is achieved...

..To determine the disability, distress and employment status of new neurology outpatients with physical symptoms unexplained by organic disease and to compare them with patients with symptoms explained by organic disease...

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..Previous studies of this topic have been limited by being of only single centres or lacking in detail. We aimed to describe the neurological diagnoses made in a large series of referrals to neurology outpatient clinics...

..The purpose of the study was to determine the prevalence and associations of clinically relevant fatigue (CRF) in men with biochemically controlled prostate cancer on long-term androgen deprivation therapy (ADT)...

..A new diagnosis, which with hindsight explained the original symptoms, rarely became apparent to the patient's primary care doctor in the 18 months following the initial hospital consultation...

..We tested the hypothesis that adding CBT-based guided self-help (GSH) to the usual care (UC) received by patients improves outcomes...

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..All doctors recognise that some patients are more "difficult to help" than others, but the issue has received little systematic investigation in neurological practice...

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..We undertook a systematic review to examine the hypotheses that depression is more commonly associated with left-hemisphere strokes than with right-hemisphere strokes and with lesions of the left anterior brain than with other regions...

..Although the symptoms of unilateral "medically unexplained" or "functional" weakness and sensory disturbance present commonly to neurologists, little is known about their long term prognosis...

..Services to treat distress in cancer patients should be organised to target patients by characteristics other than their cancer diagnosis...

..In a previous cross sectional study of 300 consecutive new attenders at neurology outpatient clinics, 90 were detected with symptoms that were rated as "not at all" or only "somewhat" explained by organic disease...

..To test the hypothesis that unilateral motor and sensory symptoms unexplained by identifiable disease are more common on the left side of the body than the right...

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..Little is known about the prevalence and associations of clinically relevant fatigue (CRF) in recurrence-free prostate cancer survivors...

..We also determined the adequacy of treatment received...

..We aimed to describe the outcome of those caring for stroke patients and to identify both patient and caregiver factors that are associated with poor caregiver outcomes...

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..2) To determine the sensitivity and specificity of various HADS cut-off scores. (3) To recommend an optimal HADS cut-off score for use in this population...

..It is a common clinical problem in neurology but its neural correlates remain poorly understood...

..There is little information on how to best measure poststroke fatigue. Our aim was to identify which currently available fatigue scale is most valid, feasible, and reliable in stroke patients...

..The objective of this study was to evaluate electronic diaries as a tool for investigating associations between physical symptoms and psychological variables...

..This study aimed to determine the prevalence of such thoughts in cancer outpatients and which patients are most likely to have them...

..This study aimed to determine which methods of remote symptom assessment cancer outpatients would be comfortable using, including those involving information technology, and whether this varied with age and gender...

..This article describes the design and delivery of DCPC as given in the SMaRT Oncology trials...

..In this article, the authors report on the performance of the PHQ-9 as a screening instrument for major depressive disorder (MDD) in patients with cancer...

..The objective of this study was to determine and compare patient and general practitioner (GP) preferences for the treatment of depression in patients with cancer...

..To determine whether a higher score on Item 9 of the Patient Health Questionnaire-9 (range zero to three) was more likely to indicate suicidality as determined at subsequent clinical interview in cancer outpatients...

..To describe the problems reported by people with cancer and major depressive disorder as elicited before starting problem-solving therapy (PST)...

..We discuss the theoretical and practical implications of these findings for the concept of conversion disorder...

..Despite the epidemiological evidence for links between physical symptoms and mental processes, prior diary studies have shown inconsistent associations and generally been limited to single symptom and psychological variable pairs...

..A multidisciplinary approach involving concurrent physical and psychological treatments is often recommended, although further study is required to determine the best approaches to explain and treat these conditions...

..An alternative view, that gives primacy to the symptoms rather than a disorder, may enable more precise research questions to be posed...

..In this study we examine the meanings of these labels for patients, which have the least potential to offend, and consequently to provide a more positive basis for further management...

..More effective ways of identifying and treating patients with both cancer and depression are therefore urgently required...

..The aim of this study was to examine the illness beliefs and locus of control of patients with recent onset pseudoseizures and to compare these with patients with recent onset epilepsy...

..quot;Psychosomatic medicine" is the new name for the seventh subspecialty of psychiatry. More needs to be done to educate the media about its actual meaning to make it attractive to patients...

..Indeed, a substantial proportion of patients may actually prefer them...

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..La belle indifférence refers to an apparent lack of concern shown by some patients towards their symptoms. It is often regarded as typical of conversion symptoms/hysteria...

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..To describe changes in personality after stroke and effects on carers...

..It should be borne in mind that a patient may have both a functional and an organic disorder...

..e., percentage drops)...

..To study the association of acceptance of disability with depression following stroke and its ability to predict depression at follow-up...

..However, by selecting both cases and controls with recent onset symptoms, the potential bias of differing illness durations and complicating factors of chronicity that have affected previous studies was avoided...

..We set out to determine whether anorexia nervosa exists in a culture where the pressure to be thin is less pervasive...

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..An international, multidisciplinary, and multiinstitutional consensus project was completed to summarize current knowledge on unexplained symptoms after terrorism and war...

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..While fatigue after stroke is a common problem, it has no generally accepted definition. Our aim was to develop a case definition for post-stroke fatigue and to test its psychometric properties...

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..This systematic review and meta-analysis aims to review the available evidence and make recommendations for practice and research...

..Additional follow-up will be needed to assess the long-term effects of these larger fraction sizes on normal-tissue sequelae and the impact of this fractionation schedule on treatment efficacy...

..The aim of this study was to investigate fear of recurrent stroke and beliefs about its causes and prevention...