Tyson V Sharp

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription
    Tyson V Sharp
    Cancer Research UK, Viral Oncology Group, Wolfson Institute for Biomedical Research, Cruciform Building, University College London, London WC1E 6BT, United Kingdom
    Proc Natl Acad Sci U S A 101:16531-6. 2004
  2. pmc Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin
    Hsei Wei Wang
    The Cancer Research UK Viral Oncology Group, Wolfson Institute for Biomedical Research, Cruciform Building, University College London, London WC1E 6BT, UK
    EMBO J 21:2602-15. 2002
  3. pmc K15 protein of Kaposi's sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function
    Tyson V Sharp
    The CRC Viral Oncology Group, Wolfson Institute for Biomedical Research, University College London, London, United Kingdom WC1E 6BT
    J Virol 76:802-16. 2002
  4. doi request reprint Differential subcellular localisation of the tumour suppressor protein LIMD1 in breast cancer correlates with patient survival
    Ian Spendlove
    Academic and Clinical Department of Oncology, University of Nottingham, Nottingham, United Kingdom
    Int J Cancer 123:2247-53. 2008

Detail Information

Publications4

  1. pmc LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription
    Tyson V Sharp
    Cancer Research UK, Viral Oncology Group, Wolfson Institute for Biomedical Research, Cruciform Building, University College London, London WC1E 6BT, United Kingdom
    Proc Natl Acad Sci U S A 101:16531-6. 2004
    ..Our data indicate that LIMD1 is a tumor-suppressor gene, the protein product of which functionally interacts with pRB and the loss of which promotes lung carcinogenesis...
  2. pmc Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin
    Hsei Wei Wang
    The Cancer Research UK Viral Oncology Group, Wolfson Institute for Biomedical Research, Cruciform Building, University College London, London WC1E 6BT, UK
    EMBO J 21:2602-15. 2002
    ..These data also suggest that survivin-DeltaEx3 might function by a similar mechanism to that of K7. We denote K7 as vIAP (viral inhibitor-of-apoptosis protein)...
  3. pmc K15 protein of Kaposi's sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function
    Tyson V Sharp
    The CRC Viral Oncology Group, Wolfson Institute for Biomedical Research, University College London, London, United Kingdom WC1E 6BT
    J Virol 76:802-16. 2002
    ..The putative functions of K15 with respect to its interaction with HAX-1 are discussed...
  4. doi request reprint Differential subcellular localisation of the tumour suppressor protein LIMD1 in breast cancer correlates with patient survival
    Ian Spendlove
    Academic and Clinical Department of Oncology, University of Nottingham, Nottingham, United Kingdom
    Int J Cancer 123:2247-53. 2008
    ..The possible functions of LIMD1 localisation within the nucleus and cytoplasm and its relationship to tumour prognosis are discussed...