Paul M Sharp

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Forces that influence the evolution of codon bias
    Paul M Sharp
    Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JT, UK
    Philos Trans R Soc Lond B Biol Sci 365:1203-12. 2010
  2. pmc The evolution of HIV-1 and the origin of AIDS
    Paul M Sharp
    Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JT, UK
    Philos Trans R Soc Lond B Biol Sci 365:2487-94. 2010
  3. pmc Origins of HIV and the AIDS pandemic
    Paul M Sharp
    Institute of Evolutionary Biology and Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Cold Spring Harb Perspect Med 1:a006841. 2011
  4. pmc Impact of translational selection on codon usage bias in the archaeon Methanococcus maripaludis
    Laura R Emery
    Institute of Evolutionary Biology, University of Edinburgh, King s Buildings, Edinburgh EH9 3JT, UK
    Biol Lett 7:131-5. 2011

Collaborators

Detail Information

Publications4

  1. pmc Forces that influence the evolution of codon bias
    Paul M Sharp
    Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JT, UK
    Philos Trans R Soc Lond B Biol Sci 365:1203-12. 2010
    ..Highly expressed genes in Escherichia coli appear to be under continuing strong selection, whereas selection is very weak in genes expressed at low levels...
  2. pmc The evolution of HIV-1 and the origin of AIDS
    Paul M Sharp
    Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, Edinburgh EH9 3JT, UK
    Philos Trans R Soc Lond B Biol Sci 365:2487-94. 2010
    ..Tracing the genetic changes that occurred as monkey viruses adapted to infect first chimpanzees and then humans may provide insights into the causes of the pathogenicity of these viruses...
  3. pmc Origins of HIV and the AIDS pandemic
    Paul M Sharp
    Institute of Evolutionary Biology and Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh EH9 3JT, United Kingdom
    Cold Spring Harb Perspect Med 1:a006841. 2011
    ..Tracing the genetic changes that occurred as SIVs crossed from monkeys to apes and from apes to humans provides a new framework to examine the requirements of successful host switches and to gauge future zoonotic risk...
  4. pmc Impact of translational selection on codon usage bias in the archaeon Methanococcus maripaludis
    Laura R Emery
    Institute of Evolutionary Biology, University of Edinburgh, King s Buildings, Edinburgh EH9 3JT, UK
    Biol Lett 7:131-5. 2011
    ..Weaker bias among the codons for fourfold degenerate AAs is consistent with the small number of tRNA genes in the M. maripaludis genome...