Affiliation: University of Bristol
- Early-life exposure to endotoxin alters hypothalamic-pituitary-adrenal function and predisposition to inflammationN Shanks
Division of Medicine, University of Bristol, Bristol Royal Infirmary Labs, Marlborough Street, Bristol, BS2 8HW, United Kingdom
Proc Natl Acad Sci U S A 97:5645-50. 2000..These findings demonstrate a potent and long-term effect of neonatal exposure to inflammatory stimuli that can program major changes in the development of both neuroendocrine and immunological regulatory mechanisms...
- Inflammatory disease as chronic stressN Shanks
Department of Medicine, University of Bristol, United Kingdom
Ann N Y Acad Sci 840:599-607. 1998..It is suggested that alterations in CRH regulation in response to either acute or chronic inflammation may contribute as etiological factors to both psychiatric (i.e. neuropsychiatric SLE) and stress-related disease...
- Differential immune reactivity to stress in BALB/cByJ and C57BL/6J mice: in vivo dependence on macrophagesN Shanks
Department of Medicine, University of Bristol, Bristol Royal Infirmary Labs, UK
Physiol Behav 65:95-103. 1998....
- The hypothalamic-pituitary-adrenal axis response to endotoxin is attenuated during lactationN Shanks
Department of Medicine, University of Bristol, Bristol Royal Infirmary, Bristol, UK
J Neuroendocrinol 11:857-65. 1999..These data demonstrate that there is a lower level of free circulating glucocorticoid in response to inflammatory stimuli and suggests that communication between the immune and endocrine systems may be altered during lactation...
- Habituation and cross-sensitization of stress-induced hypothalamic-pituitary-adrenal activity: effect of lesions in the paraventricular nucleus of the thalamus or bed nuclei of the stria terminalisG A Fernandes
University Research Centre in Neuroendocrinology, University of Bristol, Dorothy Crowfoot Hodgkin Laboratories, Bristol Royal Infirmary, Bristol, UK
J Neuroendocrinol 14:593-602. 2002....
- Are adhesion molecules involved in stress-induced changes in lymphocyte distribution?M E Bauer
Division of Medicine, Dorothy Crowfoot Hodgkin Laboratories, University of Bristol, UK
Life Sci 69:1167-79. 2001....
- Peripartum plasticity within the hypothalamo-pituitary-adrenal axisS L Lightman
University Research Centre for Neuroendocrinology, Dorothy Crowfoot Hodgkin Laboratories, University of Bristol, Bristol Royal Infirmary, Bristol BS2 8HW, UK
Prog Brain Res 133:111-29. 2001..In view of its role in other reproductive behaviors, a stress-inhibiting effect of oxytocin may reflect a more widespread co-ordinating role in the peripartum animal...
- Alterations in hypothalamic-pituitary-adrenal function correlated with the onset of murine SLE in MRL +/+ and lpr/lpr miceN Shanks
University of Bristol, BRI Laboratories, Marlborough Street, Bristol, BS2 8HW, United Kingdom
Brain Behav Immun 13:348-60. 1999....
- Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in ratsR J Windle
Department of Anatomy, School of Medical Sciences, University of Bristol, United Kingdom
Endocrinology 138:2829-34. 1997..Thus, oxytocin exerts a central anxiolytic-like effect on both endocrine and behavioral systems and could play a role in moderating behavioral and physiological responses to stress...
- The role of stressors and psychosocial variables in the stress process: a study of chronic caregiver stressK Vedhara
Department of Medicine, University of Bristol, Clifton, United Kingdom
Psychosom Med 62:374-85. 2000....