R A Seymour

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi The efficacy of three different surgical techniques in the management of drug-induced gingival overgrowth
    M Mavrogiannis
    School of Dental Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    J Clin Periodontol 33:677-82. 2006
  2. ncbi Is gum disease killing your patient?
    R A Seymour
    School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4BW
    Br Dent J 206:551-2. 2009
  3. ncbi An investigation into the efficacy of intravenous diclofenac in post-operative dental pain
    R A Seymour
    Department of Restorative Dentistry, Dental School, Newcastle upon Tyne, UK
    Eur J Clin Pharmacol 56:447-52. 2000
  4. ncbi Infective endocarditis, dentistry and antibiotic prophylaxis; time for a rethink?
    R A Seymour
    Department of Restorative Dentistry, The Dental School, University of Newcastle upon Tyne
    Br Dent J 189:610-6. 2000
  5. ncbi Determinants of gingival overgrowth severity in organ transplant patients. An examination of the rôle of HLA phenotype
    J M Thomason
    Department of Restorative Dentistry, University of Newcastle, Newcastle upon Tyne, UK
    J Clin Periodontol 23:628-34. 1996
  6. ncbi Nifedipine pharmacological variables as risk factors for gingival overgrowth in organ-transplant patients
    J M Thomason
    Department of Restorative Dentistry, Dental School, University of Newcastle upon Tyne, England
    Clin Oral Investig 1:35-9. 1997
  7. ncbi The effect of multiple anticonvulsant therapy on the expression of phenytoin-induced gingival overgrowth
    F Kamali
    Wolfson Unit of Clinical Pharmacology, University of Newcastle, Newcastle upon Tyne, UK
    J Clin Periodontol 26:802-5. 1999
  8. ncbi Dentistry and the medically compromised patient
    R A Seymour
    School of Dental Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NED2 4BW
    Surgeon 1:207-14. 2003
  9. ncbi Change in cardiovascular risk status after dental clearance
    J S Ellis
    School of Dental Sciences, University of Newcastle upon Tyne, Framlington Place, UK
    Br Dent J 202:543-4. 2007
  10. ncbi Incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients in general medical practice
    J M Thomason
    Dental School, University of Newcastle upon Tyne, England
    Community Dent Oral Epidemiol 20:288-91. 1992

Detail Information

Publications26

  1. ncbi The efficacy of three different surgical techniques in the management of drug-induced gingival overgrowth
    M Mavrogiannis
    School of Dental Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    J Clin Periodontol 33:677-82. 2006
    ..Flap surgery offered no advantage over conventional gingivectomy with respect to the rate of recurrence. CONCLUSIONS: DIGO can be managed by a variety of techniques. Laser excision results in a reduced rate of recurrence...
  2. ncbi Is gum disease killing your patient?
    R A Seymour
    School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4BW
    Br Dent J 206:551-2. 2009
    ..This has been shown to improve hyperglycaemic control in diabetics, reduce the prevalence of adverse pregnancy outcomes and improve surrogate markers that may be of benefit in patients suffering from coronary heart disease...
  3. ncbi An investigation into the efficacy of intravenous diclofenac in post-operative dental pain
    R A Seymour
    Department of Restorative Dentistry, Dental School, Newcastle upon Tyne, UK
    Eur J Clin Pharmacol 56:447-52. 2000
    ..To evaluate the efficacy of single doses of intravenous diclofenac sodium (25, 50 and 75 mg) in patients with post-operative pain after third-molar surgery in a randomised, placebo-controlled study...
  4. ncbi Infective endocarditis, dentistry and antibiotic prophylaxis; time for a rethink?
    R A Seymour
    Department of Restorative Dentistry, The Dental School, University of Newcastle upon Tyne
    Br Dent J 189:610-6. 2000
    ..To provide a critical review of the current evidence that links dental treatment to infective endocarditis (IE) and appraise the risks of antibiotic chemoprophylaxis...
  5. ncbi Determinants of gingival overgrowth severity in organ transplant patients. An examination of the rôle of HLA phenotype
    J M Thomason
    Department of Restorative Dentistry, University of Newcastle, Newcastle upon Tyne, UK
    J Clin Periodontol 23:628-34. 1996
    ..The data at present available would suggest that the severity of gingival overgrowth is also significantly associated with the HLA-B37 phenotype...
  6. ncbi Nifedipine pharmacological variables as risk factors for gingival overgrowth in organ-transplant patients
    J M Thomason
    Department of Restorative Dentistry, Dental School, University of Newcastle upon Tyne, England
    Clin Oral Investig 1:35-9. 1997
    ..01) once adjusted for other known risk factors (R2 for the model = 55%)...
  7. ncbi The effect of multiple anticonvulsant therapy on the expression of phenytoin-induced gingival overgrowth
    F Kamali
    Wolfson Unit of Clinical Pharmacology, University of Newcastle, Newcastle upon Tyne, UK
    J Clin Periodontol 26:802-5. 1999
    ....
  8. ncbi Dentistry and the medically compromised patient
    R A Seymour
    School of Dental Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NED2 4BW
    Surgeon 1:207-14. 2003
    ..Although the association is convincing, casualty has not been established. If casualty for this relationship can be confirmed then the delivery of dental care and the promotion of oral health will receive a significant impetus...
  9. ncbi Change in cardiovascular risk status after dental clearance
    J S Ellis
    School of Dental Sciences, University of Newcastle upon Tyne, Framlington Place, UK
    Br Dent J 202:543-4. 2007
    ..CRP levels have also been shown to decrease following periodontal therapy. CRP is a reliable marker of the acute phase reaction to infections and/or inflammation and is a powerful predictor of future coronary events...
  10. ncbi Incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients in general medical practice
    J M Thomason
    Dental School, University of Newcastle upon Tyne, England
    Community Dent Oral Epidemiol 20:288-91. 1992
    ..The overall incidence of clinically significant overgrowth (13%) is considerably less than in other studies...
  11. ncbi Gingival fibroblasts grown from cyclosporin-treated patients show a reduced production of matrix metalloproteinase-1 (MMP-1) compared with normal gingival fibroblasts, and cyclosporin down-regulates the production of MMP-1 stimulated by pro-inflammatory c
    T Z Sukkar
    School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, UK
    J Periodontal Res 42:580-8. 2007
    ....
  12. ncbi Photographic scoring of gingival overgrowth
    J S Ellis
    The Dental School, University of Newcastle upon Tyne, UK
    J Clin Periodontol 28:81-5. 2001
    ..71). CONCLUSIONS: The results indicate that this method is suitable for large-scale population studies where it also has the advantage of providing a continuous scale of gingival changes for subsequent statistical analysis...
  13. ncbi Immunolocalization of collagenase (MMP-1) and stromelysin (MMP-3) in the gingival tissues of organ transplant patients medicated with cyclosporin
    J M Thomason
    Department of Restorative Dentistry, The University of Newcastle, Newcastle upon Tyne, UK
    J Clin Periodontol 25:554-60. 1998
    ....
  14. ncbi An investigation into the comparative efficacy of soluble aspirin and solid paracetamol in postoperative pain after third molar surgery
    R A Seymour
    Department of Restorative Dentistry, Dental School, University of Newcastle, Newcastle upon Tyne, England R A
    Br Dent J 194:153-7; discussion 149. 2003
    ..To compare the efficacy of soluble aspirin 900 mg and paracetamol 1,000 mg in patients with postoperative pain after third molar surgery...
  15. ncbi Phenytoin metabolism to 5-(4-hydroxyphenyl)-5-phenylhydantoin (HPPH) in man, cat and rat in vitro and in vivo, and susceptibility to phenytoin-induced gingival overgrowth
    F Kamali
    Wolfson Unit of Clinical Pharmacology, University of Newcastle, Newcastle upon Tyne, UK
    J Periodontal Res 34:145-53. 1999
    ..The results suggest that the rapid metabolism and elimination of PHT and HPPH in the rat may enable it to become more resistant towards developing gingival overgrowth, compared to the cat and man...
  16. ncbi Cardiovascular diseases and periodontology
    R A Seymour
    Department of Restorative Dentistry, The Dental School, University of Newcastle, Framlington Place, Newcastle upon Tyne NE2 4BW, UK
    J Clin Periodontol 30:279-92. 2003
    ..The various diseases and their treatments can have an impact upon the periodontium and the delivery of periodontal care...
  17. ncbi Post-transplant lymphoproliferative disorders presenting as gingival overgrowth in patients immunosuppressed with ciclosporin. A report of two cases
    S L Rolland
    School of Dental Sciences, University of Newcastle, Framlington Place, Newcastle upon Tyne, UK
    J Clin Periodontol 31:581-5. 2004
    ..This paper describes two cases of PTLD occurring in gingival tissues, in patients receiving ciclosporin following cardiac transplantation...
  18. ncbi The management of drug-induced gingival overgrowth
    M Mavrogiannis
    School of Dental Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, UK
    J Clin Periodontol 33:434-9. 2006
    ..Surgical treatment is often the most reliable option and scalpel gingivectomy remains the treatment of choice. Further investigations are required to develop appropriate management strategies to prevent recurrence of DIGO...
  19. ncbi Analysis of changes in gingival contour from three-dimensional co-ordinate data in subjects with drug-induced gingival overgrowth
    J M Thomason
    School of Dental Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4BW, UK
    J Clin Periodontol 32:1069-75. 2005
    ....
  20. ncbi Are alcohol containing mouthwashes safe?
    C W de A Werner
    School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne
    Br Dent J 207:E19; discussion 488-9. 2009
    ..In view of this outcome and the hypothetical risk of oral cancer, it would seem prudent that members of the dental team advise their patients accordingly...
  21. ncbi Antibiotic prophylaxis for patients with joint prostheses - still a dilemma for dental practitioners
    R A Seymour
    Department of Restorative Dentistry, School of Dental Sciences, University of Newcastle upon Tyne, Framlington Place, NE2 4BW
    Br Dent J 194:649-53. 2003
    ..To provide a critical review of the current evidence that implicates dental-induced bacteraemia as a risk for joint infections in patients fitted with joint prostheses and appraise the need for antibiotic prophylaxis...
  22. ncbi The efficacy of topical hyaluronic acid in the management of oral lichen planus
    A Nolan
    Department of Oral Medicine, University of Dundee, Dental School, Dundee, UK
    J Oral Pathol Med 38:299-303. 2009
    ..The aim of this study was to evaluate the efficacy of a topical hyaluronic acid (HA) gel preparation (0.2%) in the management of oral lichen planus (OLP)...
  23. ncbi Prevalence of gingival overgrowth in transplant patients immunosuppressed with tacrolimus
    J S Ellis
    School of Dental Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4BW, UK
    J Clin Periodontol 31:126-31. 2004
    ....
  24. ncbi Human diseases - the Newcastle experience
    M Greenwood
    Newcastle University, School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4BW
    Br Dent J 203:595-8. 2007
    ..Previously, many of these topics were taught and examined separately. In this article, we would like to share the Newcastle experience of developing a course in human diseases alongside the GDC guidelines...
  25. ncbi Are dental infections a cause of brain abscess? Case report and review of the literature
    M A Corson
    Newcastle upon Tyne NHS Trust, Dental Hospital and School, Richardson Road, Newcastle upon Tyne, NE2 4AZ, UK
    Oral Dis 7:61-5. 2001
    ..The causal organism should be identified in both oral and cranial sites...
  26. ncbi Salivary proteins and cytokines in drug-induced gingival overgrowth
    S Ruhl
    Department of Operative Dentistry and Periodontology, Dental School, University of Regensburg, 93042 Regensburg, Germany
    J Dent Res 83:322-6. 2004
    ..Thus, inflammatory cytokines and albumin are confined to whole saliva and are associated with GO, whereas its content of EGF and NGF appears unaffected by cyclosporin...