M G Semple
Affiliation: University of Liverpool
- Left pulmonary artery sling presenting as unilateral echogenic lung on 20-week detailed antenatal ultrasound examinationMalcolm G Semple
Institute of Child Health, University of Liverpool, Alder Hey, Eaton Road, Liverpool, L12 2AP, UK
Pediatr Radiol 33:567-9. 2003..The infant successfully underwent corrective surgery...
- Dual infection of infants by human metapneumovirus and human respiratory syncytial virus is strongly associated with severe bronchiolitisMalcolm G Semple
Department of Child Health, University of Liverpool, Liverpool, United Kingdom
J Infect Dis 191:382-6. 2005..99 [95% confidence interval, 5.0-24.12]; P<.001, by Fisher exact test). Dual infection by hMPV and hRSV is associated with severe bronchiolitis...
- Most human metapneumovirus and human respiratory syncytial virus in infant nasal secretions is cell freeM G Semple
Division of Child Health, School of Reproductive and Developmental Medicine, School of Infection and Host Defence, University of Liverpool, United Kingdom
J Clin Virol 40:241-4. 2007..Nasopharyngeal secretions aspirated from infants with bronchiolitis (NPA) are a valuable resource for the study of virus dynamics and local inflammatory responses, however samples are small and difficult to manipulate...
- Detection and characterisation of human metapneumovirus from children with acute respiratory symptoms in north-west England, UKMark J Hopkins
Liverpool Specialist Virology Centre, Royal Liverpool University Hospital, Liverpool, UK
J Clin Virol 42:273-9. 2008..Five distinct lineages of the virus genome have been described...
- Severe respiratory syncytial virus bronchiolitis in infants is associated with reduced airway interferon gamma and substance PMalcolm G Semple
Division of Child Health, School of Reproductive and Developmental Medicine, University of Liverpool, Liverpool, United Kingdom
PLoS ONE 2:e1038. 2007..Severe human respiratory syncytial virus (hRSV) bronchiolitis in previously well infants may be due to differences in the innate immune response to hRSV infection...
- CD8+ T cell responses in bronchoalveolar lavage fluid and peripheral blood mononuclear cells of infants with severe primary respiratory syncytial virus infectionsJojanneke Heidema
Division of Pediatrics, Wilhelmina Children s Hospital, University Medical Center, Utrecht, The Netherlands
J Immunol 179:8410-7. 2007..The lack of a correlation between RSV-specific T cell numbers and parameters of disease severity make a prominent role in immune pathology unlikely, in contrast the T cells might be involved in the recovery process...