Research Topics
| Marisa SegalSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
Mitotic exit control: a space and time odysseyMarisa Segal
Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
Curr Biol 21:R857-9. 2011..Now it emerges that signals from both Tem1 and the yeast Polo kinase Cdc5 converge onto the MEN kinase Cdc15 to accurately restrict MEN activation to late mitosis...
Mechanism for astral microtubule capture by cortical Bud6p priming spindle polarity in S. cerevisiaeRogier ten Hoopen
Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
Curr Biol 22:1075-83. 2012..This activity resides in N-terminal sequences away from a domain linked to actin organization. Kip3p (kinesin-8), a MT depolymerase, may be implicated, but other molecular details are essentially unknown...
Actin-mediated delivery of astral microtubules instructs Kar9p asymmetric loading to the bud-ward spindle poleCristina Cepeda-García
Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom
Mol Biol Cell 21:2685-95. 2010..Our findings also explain the link between Kar9p polarity and the choice setting aside the old spindle pole for daughter-bound fate...
Dissecting the involvement of formins in Bud6p-mediated cortical capture of microtubules in S. cerevisiaeNathalie Delgehyr
Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
J Cell Sci 121:3803-14. 2008....
Cortical capture of microtubules and spindle polarity in budding yeast - where's the catch?Stephen M Huisman
Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK
J Cell Sci 118:463-71. 2005..Thus, this actin-independent pathway for spindle orientation might also be influenced by Cdk...
Phosphorylation of Spc110p by Cdc28p-Clb5p kinase contributes to correct spindle morphogenesis in S. cerevisiaeStephen M Huisman
Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK
J Cell Sci 120:435-46. 2007..Together, our results point to the function of cyclin-dependent kinase phosphorylation of Spc110p and provide, in addition, support to a model for Clb5p control of spindle polarity at the level of astral microtubule organisation...
Ase1p phosphorylation by cyclin-dependent kinase promotes correct spindle assembly in S. cerevisiaeM Angeles Juanes
Department of Genetics, University of Cambridge, Cambridge, UK
Cell Cycle 10:1988-97. 2011....
Differential contribution of Bud6p and Kar9p to microtubule capture and spindle orientation in S. cerevisiaeStephen M Huisman
Department of Genetics, University of Cambridge, Cambridge, CB2 3EH UK
J Cell Biol 167:231-44. 2004..Together, these results demonstrate Bud6p function in MT capture at the cell cortex, independent of Kar9p-mediated MT delivery along actin cables...
Spindle polarity in S. cerevisiae: MEN can tellMonique F M A Smeets
Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
Cell Cycle 1:308-11. 2002..This system operates irrespective of intrinsic spindle polarity to ensure that it is always the pole translocating into the bud that carries the signal to regulate mitotic exit...
