S R Seaman

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint A Bayesian partition model for case-control studies on highly polymorphic candidate genes
    S R Seaman
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, England
    Genet Epidemiol 22:356-68. 2002
  2. doi request reprint Review of inverse probability weighting for dealing with missing data
    Shaun R Seaman
    MRC Biostatistics Unit, Institute of Public Health, Forvie Site, Robinson Way, Cambridge, UK
    Stat Methods Med Res 22:278-95. 2013
  3. pmc Multiple imputation of missing covariates with non-linear effects and interactions: an evaluation of statistical methods
    Shaun R Seaman
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 0SR, UK
    BMC Med Res Methodol 12:46. 2012
  4. pmc Combining multiple imputation and inverse-probability weighting
    Shaun R Seaman
    MRC Biostatistics Unit, Cambridge, UK
    Biometrics 68:129-37. 2012
  5. doi request reprint Doubly robust generalized estimating equations for longitudinal data
    Shaun Seaman
    Institute of Public Health, Robinson Way, Cambridge CB2 0SR, UK
    Stat Med 28:937-55. 2009
  6. pmc Mortality from overdose among injecting drug users recently released from prison: database linkage study
    S R Seaman
    Medical Research Council Biostatistics Unit, Institute of Public Health, Cambridge
    BMJ 316:426-8. 1998
  7. ncbi request reprint Effect of genotyping error on type-I error rate of affected sib pair studies with genotyped parents
    S R Seaman
    Max Planck Institute of Psychiatry, Munich, Germany
    Hum Hered 59:157-64. 2005
  8. ncbi request reprint Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity
    R H S R Roxburgh
    Neurology Department, Cambridge University, UK
    Neurology 64:1144-51. 2005
  9. pmc Rapid simulation of P values for product methods and multiple-testing adjustment in association studies
    S R Seaman
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Hum Genet 76:399-408. 2005
  10. ncbi request reprint Familial effects on the clinical course of multiple sclerosis
    A E Hensiek
    Department of Clinical Neuroscience, University of Cambridge Clinical School, Addenbrooke s Hospital, Box 165, Cambridge CB2 2QQ, UK
    Neurology 68:376-83. 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint A Bayesian partition model for case-control studies on highly polymorphic candidate genes
    S R Seaman
    MRC Biostatistics Unit, Institute of Public Health, Cambridge, England
    Genet Epidemiol 22:356-68. 2002
    ..The partition model enables genotype risks to be estimated more accurately and the alleles to be ranked according to risk...
  2. doi request reprint Review of inverse probability weighting for dealing with missing data
    Shaun R Seaman
    MRC Biostatistics Unit, Institute of Public Health, Forvie Site, Robinson Way, Cambridge, UK
    Stat Methods Med Res 22:278-95. 2013
    ..We discuss the choice of missingness model and methods such as weight truncation, weight stabilisation and augmented IPW. The use of IPW is illustrated on data from the 1958 British Birth Cohort...
  3. pmc Multiple imputation of missing covariates with non-linear effects and interactions: an evaluation of statistical methods
    Shaun R Seaman
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 0SR, UK
    BMC Med Res Methodol 12:46. 2012
    ..In 'passive imputation' a value X* is imputed for X and then X2 is imputed as (X*)2. A recent proposal is to treat X2 as 'just another variable' (JAV) and impute X and X2 under multivariate normality...
  4. pmc Combining multiple imputation and inverse-probability weighting
    Shaun R Seaman
    MRC Biostatistics Unit, Cambridge, UK
    Biometrics 68:129-37. 2012
    ..IPW/MI is applied to data from the National Child Development Study...
  5. doi request reprint Doubly robust generalized estimating equations for longitudinal data
    Shaun Seaman
    Institute of Public Health, Robinson Way, Cambridge CB2 0SR, UK
    Stat Med 28:937-55. 2009
    ..We describe DR GEE, and illustrate their use on simulated data. We also analyse the INITIO randomized clinical trial of HIV therapy allowing for MAR dropout...
  6. pmc Mortality from overdose among injecting drug users recently released from prison: database linkage study
    S R Seaman
    Medical Research Council Biostatistics Unit, Institute of Public Health, Cambridge
    BMJ 316:426-8. 1998
    ..5 (1.7 to 11.7) for death from overdose. After temporal matching these risks became 1.8 (0.4 to 9.2). CONCLUSION: Prisons should evaluate interventions to reduce the risk of death from overdose after release...
  7. ncbi request reprint Effect of genotyping error on type-I error rate of affected sib pair studies with genotyped parents
    S R Seaman
    Max Planck Institute of Psychiatry, Munich, Germany
    Hum Hered 59:157-64. 2005
    ..The effect of genotyping error when parents have been genotyped is unknown. We investigated the type I error rate of the single-point Mean test for studies in which genotypes of both parents are available...
  8. ncbi request reprint Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity
    R H S R Roxburgh
    Neurology Department, Cambridge University, UK
    Neurology 64:1144-51. 2005
    ..There is no consensus method for determining progression of disability in patients with multiple sclerosis (MS) when each patient has had only a single assessment in the course of the disease...
  9. pmc Rapid simulation of P values for product methods and multiple-testing adjustment in association studies
    S R Seaman
    Max Planck Institute of Psychiatry, Munich, Germany
    Am J Hum Genet 76:399-408. 2005
    ..We demonstrate the accuracy of the DSA on real and simulated data and illustrate how it might be used in the analysis of a whole-genome association study...
  10. ncbi request reprint Familial effects on the clinical course of multiple sclerosis
    A E Hensiek
    Department of Clinical Neuroscience, University of Cambridge Clinical School, Addenbrooke s Hospital, Box 165, Cambridge CB2 2QQ, UK
    Neurology 68:376-83. 2007
    ..Familial factors influence susceptibility to multiple sclerosis (MS) but it is unknown whether there are additional effects on the natural history of the disease...