Michelle S Scott

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. pmc Human miRNA precursors with box H/ACA snoRNA features
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom
    PLoS Comput Biol 5:e1000507. 2009
  2. pmc From snoRNA to miRNA: Dual function regulatory non-coding RNAs
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    Biochimie 93:1987-92. 2011
  3. pmc Characterization and prediction of protein nucleolar localization sequences
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery and Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    Nucleic Acids Res 38:7388-99. 2010
  4. pmc PNAC: a protein nucleolar association classifier
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    BMC Genomics 12:74. 2011
  5. pmc NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    BMC Bioinformatics 12:317. 2011
  6. pmc Probabilistic prediction and ranking of human protein-protein interactions
    Michelle S Scott
    School of Life Sciences Research, College of Life Sciences, University of Dundee, Scotland, UK
    BMC Bioinformatics 8:239. 2007
  7. pmc Identification of human miRNA precursors that resemble box C/D snoRNAs
    Motoharu Ono
    Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    Nucleic Acids Res 39:3879-91. 2011
  8. pmc Analysis of human small nucleolar RNAs (snoRNA) and the development of snoRNA modulator of gene expression vectors
    Motoharu Ono
    Wellcome Trust Centre for Gene Regulation and Expression, and Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, United Kingdom
    Mol Biol Cell 21:1569-84. 2010
  9. pmc Human box C/D snoRNA processing conservation across multiple cell types
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    Nucleic Acids Res 40:3676-88. 2012
  10. pmc PIPs: human protein-protein interaction prediction database
    Mark D McDowall
    School of Life Sciences Research, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, UK
    Nucleic Acids Res 37:D651-6. 2009

Collaborators

Detail Information

Publications10

  1. pmc Human miRNA precursors with box H/ACA snoRNA features
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, United Kingdom
    PLoS Comput Biol 5:e1000507. 2009
    ..The detection of small RNA molecules that share features of miRNAs and snoRNAs suggest that these classes of RNA may have an evolutionary relationship...
  2. pmc From snoRNA to miRNA: Dual function regulatory non-coding RNAs
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    Biochimie 93:1987-92. 2011
    ..Here, we explore the extent of the relationship between these types of non-coding RNA and the possible underlying evolutionary forces that shaped this subset of the current non-coding RNA landscape...
  3. pmc Characterization and prediction of protein nucleolar localization sequences
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery and Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    Nucleic Acids Res 38:7388-99. 2010
    ..NoLSs are a prevalent type of targeting motif that is distinct from nuclear localization signals and that can be computationally predicted...
  4. pmc PNAC: a protein nucleolar association classifier
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    BMC Genomics 12:74. 2011
    ..However, in most cases, we know neither the fraction of each protein pool that is nucleolus-associated nor whether their association is permanent or conditional...
  5. pmc NoD: a Nucleolar localization sequence detector for eukaryotic and viral proteins
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    BMC Bioinformatics 12:317. 2011
    ..Although many proteins have been reported to contain NoLSs, the systematic characterization of this group of targeting motifs has only recently been carried out...
  6. pmc Probabilistic prediction and ranking of human protein-protein interactions
    Michelle S Scott
    School of Life Sciences Research, College of Life Sciences, University of Dundee, Scotland, UK
    BMC Bioinformatics 8:239. 2007
    ..Furthermore, it has recently been estimated that the overall average false positive rate of available computational and high-throughput experimental interaction datasets is as high as 90%...
  7. pmc Identification of human miRNA precursors that resemble box C/D snoRNAs
    Motoharu Ono
    Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    Nucleic Acids Res 39:3879-91. 2011
    ..The data suggest that a subset of small regulatory RNAs may have evolved from box C/D snoRNAs...
  8. pmc Analysis of human small nucleolar RNAs (snoRNA) and the development of snoRNA modulator of gene expression vectors
    Motoharu Ono
    Wellcome Trust Centre for Gene Regulation and Expression, and Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, United Kingdom
    Mol Biol Cell 21:1569-84. 2010
    ..We foresee applications for snoMEN vectors in basic gene expression research, target validation, and gene therapy...
  9. pmc Human box C/D snoRNA processing conservation across multiple cell types
    Michelle S Scott
    Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK
    Nucleic Acids Res 40:3676-88. 2012
    ..Functional analyses demonstrated that this region of HBII-180C can influence the alternative splicing of FGFR3 pre-mRNA, supporting a role for some snoRNAs in the regulation of splicing...
  10. pmc PIPs: human protein-protein interaction prediction database
    Mark D McDowall
    School of Life Sciences Research, College of Life Sciences, University of Dundee, Dow Street, Dundee, DD1 5EH, UK
    Nucleic Acids Res 37:D651-6. 2009
    ..The PIPs database provides a new resource on protein-protein interactions in human that is straightforward to browse, or can be exploited completely, for interaction network modelling...