Karen P Scott

Summary

Affiliation: University of Aberdeen
Country: UK

Publications

  1. doi request reprint The influence of diet on the gut microbiota
    Karen P Scott
    Microbiology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK Electronic address
    Pharmacol Res 69:52-60. 2013
  2. doi request reprint Nutritional influences on the gut microbiota and the consequences for gastrointestinal health
    Karen P Scott
    Rowett Institute of Nutrition and Health, University of Aberdeen, Greenburn Road, Aberdeen AB21 9SB, Scotland, UK
    Biochem Soc Trans 39:1073-8. 2011
  3. pmc A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones
    Katarzyna A Kazimierczak
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, United Kingdom
    Antimicrob Agents Chemother 52:4001-9. 2008
  4. ncbi request reprint Interactions and competition within the microbial community of the human colon: links between diet and health
    Harry J Flint
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB219SB, UK
    Environ Microbiol 9:1101-11. 2007
  5. pmc Tetracycline resistome of the organic pig gut
    Katarzyna A Kazimierczak
    Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 75:1717-22. 2009
  6. pmc Microbial degradation of complex carbohydrates in the gut
    Harry J Flint
    Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen UK
    Gut Microbes 3:289-306. 2012
  7. pmc Substrate-driven gene expression in Roseburia inulinivorans: importance of inducible enzymes in the utilization of inulin and starch
    Karen P Scott
    Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Proc Natl Acad Sci U S A 108:4672-9. 2011
  8. ncbi request reprint Distribution of specific tetracycline and erythromycin resistance genes in environmental samples assessed by macroarray detection
    Andrea J Patterson
    Gut Health Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Environ Microbiol 9:703-15. 2007
  9. doi request reprint The role of the gut microbiota in nutrition and health
    Harry J Flint
    Microbiology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, UK
    Nat Rev Gastroenterol Hepatol 9:577-89. 2012
  10. ncbi request reprint Cell-associated alpha-amylases of butyrate-producing Firmicute bacteria from the human colon
    Alan G Ramsay
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, UK
    Microbiology 152:3281-90. 2006

Collaborators

Detail Information

Publications20

  1. doi request reprint The influence of diet on the gut microbiota
    Karen P Scott
    Microbiology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK Electronic address
    Pharmacol Res 69:52-60. 2013
    ....
  2. doi request reprint Nutritional influences on the gut microbiota and the consequences for gastrointestinal health
    Karen P Scott
    Rowett Institute of Nutrition and Health, University of Aberdeen, Greenburn Road, Aberdeen AB21 9SB, Scotland, UK
    Biochem Soc Trans 39:1073-8. 2011
    ..Since bacterial species have different metabolic activities, specific diets have various consequences for health, dependent on the effect exerted on the bacterial population...
  3. pmc A new tetracycline efflux gene, tet(40), is located in tandem with tet(O/32/O) in a human gut firmicute bacterium and in metagenomic library clones
    Katarzyna A Kazimierczak
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, United Kingdom
    Antimicrob Agents Chemother 52:4001-9. 2008
    ..At least 10 of the metagenomic inserts that carried tet(O/32/O) also carried tet(40), suggesting that tet(40), although previously undetected, may be an abundant efflux gene...
  4. ncbi request reprint Interactions and competition within the microbial community of the human colon: links between diet and health
    Harry J Flint
    Microbial Ecology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB219SB, UK
    Environ Microbiol 9:1101-11. 2007
    ..Oligosaccharides used as dietary prebiotics must inevitably have complex effects upon the bacterial community that include non-target organisms and the consequences of metabolic cross-feeding and changes in the gut environment...
  5. pmc Tetracycline resistome of the organic pig gut
    Katarzyna A Kazimierczak
    Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 75:1717-22. 2009
    ....
  6. pmc Microbial degradation of complex carbohydrates in the gut
    Harry J Flint
    Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen UK
    Gut Microbes 3:289-306. 2012
    ..The impact of dietary carbohydrates, including prebiotics, on human health requires understanding of the complex relationship between diet composition, the gut microbiota and metabolic outputs...
  7. pmc Substrate-driven gene expression in Roseburia inulinivorans: importance of inducible enzymes in the utilization of inulin and starch
    Karen P Scott
    Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Proc Natl Acad Sci U S A 108:4672-9. 2011
    ..The latter response may be concerned with improving bacterial access to insoluble starch particles...
  8. ncbi request reprint Distribution of specific tetracycline and erythromycin resistance genes in environmental samples assessed by macroarray detection
    Andrea J Patterson
    Gut Health Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK
    Environ Microbiol 9:703-15. 2007
    ..The macroarray proved a powerful tool to screen DNA extracted from environmental samples to identify the most abundant Tc(R) and erm(R) genes within those tested, avoiding the need for culturing and biased PCR amplification steps...
  9. doi request reprint The role of the gut microbiota in nutrition and health
    Harry J Flint
    Microbiology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, UK
    Nat Rev Gastroenterol Hepatol 9:577-89. 2012
    ..This Review considers the complex interplay between the gut microbiota, diet and health...
  10. ncbi request reprint Cell-associated alpha-amylases of butyrate-producing Firmicute bacteria from the human colon
    Alan G Ramsay
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, UK
    Microbiology 152:3281-90. 2006
    ..2.1.1). These major starch-degrading enzymes thus appear to be anchored to the cell wall in this important group of human gut bacteria...
  11. pmc Comparative analysis of sequences flanking tet(W) resistance genes in multiple species of gut bacteria
    Katarzyna A Kazimierczak
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Antimicrob Agents Chemother 50:2632-9. 2006
    ..Several different mechanisms, including mechanisms involving plasmids and conjugative transposons, appear to be involved in the horizontal transfer of tet(W) genes, but small core regions that may function as minielements are conserved...
  12. pmc Transfer of conjugative elements from rumen and human Firmicutes bacteria to Roseburia inulinivorans
    Karen P Scott
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen, Scotland AB21 9SB, United Kingdom
    Appl Environ Microbiol 74:3915-7. 2008
    ..Here the human colonic anaerobe Roseburia inulinivorans A2-194 was shown to be a transfer recipient for two conjugative transposons, Tn1545 from Eubacterium cellulosolvens and TnK10 from Clostridium saccharolyticum K10...
  13. ncbi request reprint Antibiotics and resistance genes: influencing the microbial ecosystem in the gut
    Katarzyna A Kazimierczak
    Microbial Ecology, Gut Health Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, Scotland, United Kingdom
    Adv Appl Microbiol 62:269-92. 2007
  14. pmc Mosaic tetracycline resistance genes are widespread in human and animal fecal samples
    Andrea J Patterson
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Antimicrob Agents Chemother 51:1115-8. 2007
    ..The nonmosaic tet(32) gene was isolated from a human saliva bacterium...
  15. ncbi request reprint Proposal of Roseburia faecis sp. nov., Roseburia hominis sp. nov. and Roseburia inulinivorans sp. nov., based on isolates from human faeces
    Sylvia H Duncan
    Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Int J Syst Evol Microbiol 56:2437-41. 2006
    ..nov. (type strain A2-183(T)=DSM 16839(T)=NCIMB 14029(T)), Roseburia inulinivorans sp. nov. (type strain A2-194(T)=DSM 16841(T)=NCIMB 14030(T)) and Roseburia faecis sp. nov. (type strain M72/1(T)=DSM 16840(T)=NCIMB 14031(T))...
  16. pmc Whole-genome transcription profiling reveals genes up-regulated by growth on fucose in the human gut bacterium "Roseburia inulinivorans"
    Karen P Scott
    Gut Health Division, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    J Bacteriol 188:4340-9. 2006
    ..inulinivorans during growth on fucose. Despite the lack of genome sequence information for this commensal bacterium, microarray analysis has provided a powerful tool for obtaining new information on its metabolic capabilities...
  17. pmc The Butyrivibrio fibrisolvens tet(W) gene is carried on the novel conjugative transposon TnB1230, which contains duplicated nitroreductase coding sequences
    Claire M Melville
    Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    J Bacteriol 186:3656-9. 2004
    ..tet(W) is flanked by directly repeated sequences with significant homology to oxygen-insensitive nitroreductases. The 340 nucleotides upstream of tet(W) are strongly conserved and are required for tetracycline resistance...
  18. pmc Characterization of XYN10B, a modular xylanase from the ruminal protozoan Polyplastron multivesiculatum, with a family 22 carbohydrate-binding module that binds to cellulose
    Estelle Devillard
    Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Biochem J 373:495-503. 2003
    ..The phylogenetic relationships between the XYN10B CBM22 or catalytic domain and related sequences from ruminal and non-ruminal bacteria and eukaryotes are reported. The xyn10B gene is shown to lack introns...
  19. pmc Effects of alternative dietary substrates on competition between human colonic bacteria in an anaerobic fermentor system
    Sylvia H Duncan
    Gut Microbiology and Immunology Division, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 69:1136-42. 2003
    ..Thus, considerable caution is necessary when workers attempt to predict the in vivo effects of probiotics and prebiotics from their effects in vitro...
  20. doi request reprint Evaluation of novel assays to assess the influence of different iron sources on the growth of Clostridium difficile
    Ramona C Cernat
    Microbial Ecology, Gut Health Division, Rowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, UK
    Anaerobe 18:298-304. 2012
    ..The results demonstrated that the broth microtiter assay developed here was reproducible, reliable and convenient for high-throughput analysis of the growth of C. difficile compared to alternative traditional methods...