Eugene Schuster

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Genome-wide gene expression in response to parasitoid attack in Drosophila
    Bregje Wertheim
    Centre for Evolutionary Genomics, Department of Biology, University College London, London WC1E 6BT, UK
    Genome Biol 6:R94. 2005
  2. pmc DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO
    Eugene Schuster
    Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, UK
    Mol Syst Biol 6:399. 2010
  3. ncbi request reprint Erratum to "Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans" [Mech. Ageing Dev. 127 (5) (2006) 458-472]
    Joshua J McElwee
    Department of Biology, University College London, Gower Street, London WC1E 6BT, UK
    Mech Ageing Dev 127:922-36. 2006
  4. doi request reprint Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
    Colin Selman
    Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK
    Science 326:140-4. 2009
  5. pmc Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism
    Filipe Cabreiro
    Institute of Healthy Ageing, and G E E, University College London, London WC1E 6BT, UK
    Cell 153:228-39. 2013
  6. pmc Evolutionary conservation of regulated longevity assurance mechanisms
    Joshua J McElwee
    Department of Biology, University College London, London WC1E 6BT, UK
    Genome Biol 8:R132. 2007
  7. ncbi request reprint Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans
    Joshua J McElwee
    Department of Biology, University College London, UK
    Mech Ageing Dev 127:458-72. 2006
  8. ncbi request reprint Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
    Colin Selman
    Centre for Diabetes and Endocrinology, Department of Medicine, Rayne Institute, University College London, University St, London, UK
    FASEB J 22:807-18. 2008
  9. pmc Pleiohomeotic interacts with the core transcription elongation factor Spt5 to regulate gene expression in Drosophila
    Robert Harvey
    Transcriptional Regulation Group, UCL Cancer Institute, University College London, London, United Kingdom
    PLoS ONE 8:e70184. 2013

Detail Information

Publications9

  1. pmc Genome-wide gene expression in response to parasitoid attack in Drosophila
    Bregje Wertheim
    Centre for Evolutionary Genomics, Department of Biology, University College London, London WC1E 6BT, UK
    Genome Biol 6:R94. 2005
    ..The capsule sequesters and kills the parasite. The molecular processes involved are still poorly understood, especially compared with insect humoral immunity...
  2. pmc DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO
    Eugene Schuster
    Institute of Healthy Ageing, Department of Genetics, Evolution and Environment, University College London, London, UK
    Mol Syst Biol 6:399. 2010
    ..This study demonstrates the efficacy of DamID for chromatin profiling in C. elegans...
  3. ncbi request reprint Erratum to "Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans" [Mech. Ageing Dev. 127 (5) (2006) 458-472]
    Joshua J McElwee
    Department of Biology, University College London, Gower Street, London WC1E 6BT, UK
    Mech Ageing Dev 127:922-36. 2006
    ..We postulate that this fuels increased somatic maintenance activity, as suggested by the disposable soma theory...
  4. doi request reprint Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
    Colin Selman
    Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK
    Science 326:140-4. 2009
    ..Our results demonstrate that S6K1 influences healthy mammalian life-span and suggest that therapeutic manipulation of S6K1 and AMPK might mimic CR and could provide broad protection against diseases of aging...
  5. pmc Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism
    Filipe Cabreiro
    Institute of Healthy Ageing, and G E E, University College London, London WC1E 6BT, UK
    Cell 153:228-39. 2013
    ..Thus, metformin-induced alteration of microbial metabolism could contribute to therapeutic efficacy-and also to its side effects, which include folate deficiency and gastrointestinal upset...
  6. pmc Evolutionary conservation of regulated longevity assurance mechanisms
    Joshua J McElwee
    Department of Biology, University College London, London WC1E 6BT, UK
    Genome Biol 8:R132. 2007
    ..To address this, we have applied a novel, multi-level cross-species comparative analysis to compare gene expression changes accompanying increased longevity in mutant nematodes, fruitflies and mice with reduced IIS...
  7. ncbi request reprint Diapause-associated metabolic traits reiterated in long-lived daf-2 mutants in the nematode Caenorhabditis elegans
    Joshua J McElwee
    Department of Biology, University College London, UK
    Mech Ageing Dev 127:458-72. 2006
    ..We postulate that this fuels increased somatic maintenance activity, as suggested by the disposable soma theory...
  8. ncbi request reprint Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
    Colin Selman
    Centre for Diabetes and Endocrinology, Department of Medicine, Rayne Institute, University College London, University St, London, UK
    FASEB J 22:807-18. 2008
    ..Our results therefore suggest that IRS1 signaling is an evolutionarily conserved pathway regulating mammalian life span and may be a point of intervention for therapies with the potential to delay age-related processes...
  9. pmc Pleiohomeotic interacts with the core transcription elongation factor Spt5 to regulate gene expression in Drosophila
    Robert Harvey
    Transcriptional Regulation Group, UCL Cancer Institute, University College London, London, United Kingdom
    PLoS ONE 8:e70184. 2013
    ..Our results indicate that Pho can interact with Spt5 to regulate transcription elongation in a gene specific manner. ..