Research Topics
| Martin SchroderSummaryAffiliation: University of Durham Country: UK Publications
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Detail Information
Publications
Endoplasmic reticulum stress responsesM Schroder
School of Biological and Biomedical Sciences, Durham University, Durham, UK
Cell Mol Life Sci 65:862-94. 2008..I discuss how the UPR reestablishes homeostasis, and summarize our current understanding of how the transition from protective to apoptotic UPR signaling is controlled, and how the UPR induces inflammatory signaling...
The mammalian unfolded protein responseMartin Schroder
School of Biological and Biomedical Sciences, University of Durham, Durham DH1 3LE, United Kingdom
Annu Rev Biochem 74:739-89. 2005..Finally, we summarize data that demonstrate that UPR signaling feeds into decision making in other processes previously thought to be unrelated to ER function, e.g., eukaryotic starvation responses and differentiation programs...
Divergent roles of IRE1alpha and PERK in the unfolded protein responseMartin Schroder
School of Biological and Biomedical Sciences, University of Durham, UK
Curr Mol Med 6:5-36. 2006....
The unfolded protein responseMartin Schroder
School of Biological and Biomedical Sciences, University of Durham, Durham DH1 3LE, United Kingdom
Mol Biotechnol 34:279-90. 2006..In this review, I will summarize our current knowledge about signal transduction pathways involved in transducing the unfolded protein signal from the ER to the nucleus or the cytosol...
Engineering eukaryotic protein factoriesMartin Schroder
School of Biological and Biomedical Sciences, Durham University, South Road, Durham DH1 3LE, UK
Biotechnol Lett 30:187-96. 2008..The engineering of the ER-resident protein folding machinery is discussed together with an overview of signal transduction pathways activated by heterologous protein overexpression to increase cell specific productivities...
ER stress and the unfolded protein responseMartin Schroder
School of Biological and Biomedical Sciences, University of Durham, Durham DH1 3LE, UK
Mutat Res 569:29-63. 2005..g. execution of differentiation and starvation programs...
Sensing endoplasmic reticulum stressVipul M Parmar
School of Biological and Biomedical Sciences, Durham University, Durham, UK
Adv Exp Med Biol 738:153-68. 2012..Here we focus on how ER stress and protein folding status in the ER are sensed by the ER stress sensors by summarizing results from recent structural, biochemical and genetic approaches...
Measuring signaling by the unfolded protein responseDavid J Cox
School of Biological and Biomedical Sciences, Durham University, Durham, United Kingdom
Methods Enzymol 491:261-92. 2011..This repertoire of methods will enable the newcomer to the UPR field to comprehensively assess the activation status of the UPR...
Chemical approaches towards unravelling kinase-mediated signalling pathwaysDavid R W Hodgson
Department of Chemistry, Durham University, Science Laboratories, Durham DH1 3LE, United Kingdom
Chem Soc Rev 40:1211-23. 2011..In addition, we discuss activity-based chemical profiling approaches, based on ATP analogues, for the detection of active kinases...
Ime1 and Ime2 are required for pseudohyphal growth of Saccharomyces cerevisiae on nonfermentable carbon sourcesNatalie Strudwick
Durham University, School of Biological and Biomedical Sciences, Durham DH1 3LE, United Kingdom
Mol Cell Biol 30:5514-30. 2010..Based on these findings, we propose to include exit from pseudohyphal growth and entry into meiosis in the life cycle of S. cerevisiae...
