Genomes and Genes

Claudia Schneider


Affiliation: University of Newcastle
Country: UK


  1. Wells G, Weichmann F, COLVIN D, Sloan K, Kudla G, Tollervey D, et al. The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans. Nucleic Acids Res. 2016;44:5399-409 pubmed publisher
    ..We propose that Utp24 cleaves sites A1/1 and A2/2a in yeast and human cells. ..
  2. Schneider C, Kudla G, Wlotzka W, Tuck A, Tollervey D. Transcriptome-wide analysis of exosome targets. Mol Cell. 2012;48:422-33 pubmed publisher
    ..Rrp6 was preferentially associated with structured targets, which frequently did not associate with the core exosome indicating that substrates follow multiple pathways to the nucleases. ..
  3. Schneider C, Tollervey D. Threading the barrel of the RNA exosome. Trends Biochem Sci. 2013;38:485-93 pubmed publisher
    ..They also revealed surprisingly high degradation rates for newly synthesized RNAs, particularly RNA polymerase III transcripts. ..