Affiliation: University of Birmingham
- Monocytes/macrophages express chemokine receptor CCR9 in rheumatoid arthritis and CCL25 stimulates their differentiationCaroline Schmutz
Leopold Muller Arthritis Research Centre, Keele University, Oswestry, Shropshire, SY10 7AG, UK
Arthritis Res Ther 12:R161. 2010..This study investigated the expression and function of chemokine receptor CCR9 in the peripheral blood (PB) and synovium of RA, non-RA patients and healthy volunteers...
- Leukocyte extravasation: chemokine transport and presentation by the endotheliumJim Middleton
Leopold Muller Arthritis Research Centre, Centre for Science and Technology in Medicine, Keele University at Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, United Kingdom
Blood 100:3853-60. 2002..Finally, the mechanisms of chemokine transcytosis and presentation by endothelial cells are incorporated into the current model of chemokine-driven leukocyte extravasation...
- Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5Caroline Schmutz
Leopold Muller Arthritis Research Centre, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, UK
Arthritis Res Ther 7:R217-29. 2005..More importantly, the increased level of CXCR5, a homeostatic chemokine receptor, in the RA synovium suggests that non-inflammatory receptor-ligand pairs might play an important role in the pathogenesis of RA...
- Orphan receptor GPR15/BOB is up-regulated in rheumatoid arthritisAlison Cartwright
Institute of Science and Technology in Medicine, Keele University at Leopold Muller Arthritis Research Centre, RJAH Orthopaedic Hospital, Oswestry, Shropshire, United Kingdom
Cytokine 67:53-9. 2014..This orphan receptor on monocytes/macrophages and neutrophils may play a role in RA pathophysiology. ..
- Differential binding of chemokines to macrophages and neutrophils in the human inflamed synoviumAngela M Patterson
Leopold Muller Arthritis Research Centre, Centre for Science and Technology in Medicine, Keele University at Robert Jones, Oswestry, Shropshire, UK
Arthritis Res 4:209-14. 2002..The chemokine binding sites described on phagocytes may be involved in the migration of these cells into the inflamed joint...