Natalia Savelyeva

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. ncbi request reprint Engineering DNA vaccines that include plant virus coat proteins
    Natalia Savelyeva
    Molecular Immunology Group, Cancer Sciences Division, Southampton University Hospitals Trust, Tremona Road, Southampton, SO16 6YD, UK
    Biotechnol Genet Eng Rev 20:101-14. 2003
  2. pmc Inhibition of a vaccine-induced anti-tumor B cell response by soluble protein antigen in the absence of continuing T cell help
    Natalia Savelyeva
    Molecular Immunology Group, Cancer Sciences Division, Southampton University Hospitals Trust, Southampton, Hampshire SO16 6YD, United Kingdom
    Proc Natl Acad Sci U S A 102:10987-92. 2005
  3. doi request reprint High-affinity memory B cells induced by conjugate vaccines against weak tumor antigens are vulnerable to nonconjugated antigen
    Natalia Savelyeva
    Genetic Vaccine Group, Cancer Sciences Division, School of Medicine, University of Southampton, Southampton, United Kingdom
    Blood 118:650-9. 2011
  4. pmc DNA vaccines to attack cancer
    Freda K Stevenson
    Molecular Immunology Group, Tenovus Laboratory, Cancer Sciences Division, Southampton University Hospitals Trust, Southampton SO16 6YD, UK
    Proc Natl Acad Sci U S A 101:14646-52. 2004
  5. doi request reprint Bystander stimulation of activated CD4+ T cells of unrelated specificity following a booster vaccination with tetanus toxoid
    Gianfranco Di Genova
    Cancer Sciences Division, University of Southampton School of Medicine, Southampton, UK
    Eur J Immunol 40:976-85. 2010
  6. doi request reprint DNA fusion vaccine designs to induce tumor-lytic CD8+ T-cell attack via the immunodominant cysteine-containing epitope of NY-ESO 1
    Juan Campos-Perez
    Genetic Vaccine Group, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
    Int J Cancer 133:1400-7. 2013

Detail Information

Publications6

  1. ncbi request reprint Engineering DNA vaccines that include plant virus coat proteins
    Natalia Savelyeva
    Molecular Immunology Group, Cancer Sciences Division, Southampton University Hospitals Trust, Tremona Road, Southampton, SO16 6YD, UK
    Biotechnol Genet Eng Rev 20:101-14. 2003
  2. pmc Inhibition of a vaccine-induced anti-tumor B cell response by soluble protein antigen in the absence of continuing T cell help
    Natalia Savelyeva
    Molecular Immunology Group, Cancer Sciences Division, Southampton University Hospitals Trust, Southampton, Hampshire SO16 6YD, United Kingdom
    Proc Natl Acad Sci U S A 102:10987-92. 2005
    ..The principles revealed by using a DNA vaccine have implications for all cancer vaccines designed to induce and maintain antibody responses against weak autologous tumor antigens...
  3. doi request reprint High-affinity memory B cells induced by conjugate vaccines against weak tumor antigens are vulnerable to nonconjugated antigen
    Natalia Savelyeva
    Genetic Vaccine Group, Cancer Sciences Division, School of Medicine, University of Southampton, Southampton, United Kingdom
    Blood 118:650-9. 2011
    ..The latter remain, but the majority fail to undergo isotype switch. These findings could apply to other tumor antigens and are relevant for vaccination strategies aimed to induce long-term antibody...
  4. pmc DNA vaccines to attack cancer
    Freda K Stevenson
    Molecular Immunology Group, Tenovus Laboratory, Cancer Sciences Division, Southampton University Hospitals Trust, Southampton SO16 6YD, UK
    Proc Natl Acad Sci U S A 101:14646-52. 2004
    ..Physical methods including electroporation provide increased expression without introducing additional competing antigens. A wide range of cancers can be targeted, and objective assays of response will determine efficacy...
  5. doi request reprint Bystander stimulation of activated CD4+ T cells of unrelated specificity following a booster vaccination with tetanus toxoid
    Gianfranco Di Genova
    Cancer Sciences Division, University of Southampton School of Medicine, Southampton, UK
    Eur J Immunol 40:976-85. 2010
    ..This crosstalk between a stimulated CD4(+) memory T-cell response and CD4(+) T cells activated by an unrelated antigen could be important in human subjects continually buffeted by environmental antigens...
  6. doi request reprint DNA fusion vaccine designs to induce tumor-lytic CD8+ T-cell attack via the immunodominant cysteine-containing epitope of NY-ESO 1
    Juan Campos-Perez
    Genetic Vaccine Group, Cancer Sciences Unit, Faculty of Medicine, University of Southampton, Southampton, United Kingdom
    Int J Cancer 133:1400-7. 2013
    ..These findings encourage clinical exploration of this vaccine strategy to target NY-ESO-1...