E M Santos

Summary

Affiliation: University of Exeter
Country: UK

Publications

  1. ncbi Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model
    Eduarda M Santos
    School of Biosciences, University of Exeter, Exeter, Devon EX4 4PS, United Kingdom
    Environ Sci Technol 44:820-6. 2010
  2. ncbi Follicle-stimulating hormone and its alpha and beta subunits in rainbow trout (Oncorhynchus mykiss): purification, characterization, development of specific radioimmunoassays, and their seasonal plasma and pituitary concentrations in females
    E M Santos
    School of Biological Sciences, Hatherly Laboratories, University of Exeter, Exeter EX4 4PS, United Kingdom
    Biol Reprod 65:288-94. 2001
  3. ncbi Molecular basis of sex and reproductive status in breeding zebrafish
    E M Santos
    School of Biosciences, University of Exeter, Exeter, UK
    Physiol Genomics 30:111-22. 2007
  4. ncbi Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio)
    Eduarda M Santos
    School of Biosciences, University of Exeter, Prince of Wales Road, Exeter, UK
    Aquat Toxicol 83:134-42. 2007
  5. ncbi Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish
    Tamsyn M Uren-Webster
    Hatherly Laboratories, School of Biosciences, University of Exeter, Exeter, Devon EX4 4PS, UK
    Aquat Toxicol 99:360-9. 2010
  6. ncbi Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene
    Tim D Williams
    School of Biosciences, The University of Birmingham, Birmingham, B15 2TT, UK
    Environ Sci Technol 43:6341-8. 2009
  7. ncbi Gene expression profiling for understanding chemical causation of biological effects for complex mixtures: a case study on estrogens
    Amy L Filby
    School of Biosciences, The Hatherly Laboratories, University of Exeter, Prince of Wales Road, Exeter, EX4 4PS, UK
    Environ Sci Technol 41:8187-94. 2007
  8. ncbi Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals
    Gregory C Paull
    Environmental and Molecular Fish Biology Group, School of Biosciences, Hatherly Laboratories, University of Exeter, Prince of Wales Road, Exeter EX4 4PS, United Kingdom
    Aquat Toxicol 87:115-26. 2008
  9. ncbi ELISAs for detecting vitellogenin in the fathead minnow (Pimephales promelas)-a critical analysis. Response to Mylchreest et al., Comp Biochem Physiol C 134: 251-257, 2003
    Charles R Tyler
    School of Biological and Chemical Sciences, University of Exeter, Exeter EX4 4PS, United Kingdom
    Comp Biochem Physiol C Toxicol Pharmacol 138:531-2; author reply 533-6. 2004
  10. ncbi Sexually dimorphic gene expression in the brains of mature zebrafish
    Eduarda M Santos
    School of Biosciences, University of Exeter, Prince of Wales Road, Exeter, EX4 4PS, UK
    Comp Biochem Physiol A Mol Integr Physiol 149:314-24. 2008

Collaborators

Detail Information

Publications12

  1. ncbi Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model
    Eduarda M Santos
    School of Biosciences, University of Exeter, Exeter, Devon EX4 4PS, United Kingdom
    Environ Sci Technol 44:820-6. 2010
    ....
  2. ncbi Follicle-stimulating hormone and its alpha and beta subunits in rainbow trout (Oncorhynchus mykiss): purification, characterization, development of specific radioimmunoassays, and their seasonal plasma and pituitary concentrations in females
    E M Santos
    School of Biological Sciences, Hatherly Laboratories, University of Exeter, Exeter EX4 4PS, United Kingdom
    Biol Reprod 65:288-94. 2001
    ..The presence of free GTHalpha2 subunit in the plasma similarly occurs in mammals, but its functional significance in fish has yet to be established...
  3. ncbi Molecular basis of sex and reproductive status in breeding zebrafish
    E M Santos
    School of Biosciences, University of Exeter, Exeter, UK
    Physiol Genomics 30:111-22. 2007
    ..In summary, we have identified molecular processes associated with (gonadal) sex specificity in breeding zebrafish and established a strong relationship between individual ovarian transcriptomes and reproductive status in females...
  4. ncbi Gonadal transcriptome responses and physiological consequences of exposure to oestrogen in breeding zebrafish (Danio rerio)
    Eduarda M Santos
    School of Biosciences, University of Exeter, Prince of Wales Road, Exeter, UK
    Aquat Toxicol 83:134-42. 2007
    ..The molecular mechanisms mediating some of these effects were identified and included those impacting processes central to gametogenesis in both males and females...
  5. ncbi Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the reproductive health of male zebrafish
    Tamsyn M Uren-Webster
    Hatherly Laboratories, School of Biosciences, University of Exeter, Exeter, Devon EX4 4PS, UK
    Aquat Toxicol 99:360-9. 2010
    ....
  6. ncbi Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene
    Tim D Williams
    School of Biosciences, The University of Birmingham, Birmingham, B15 2TT, UK
    Environ Sci Technol 43:6341-8. 2009
    ..Metabolic pathways were identified where both gene expression and metabolite concentrations were altered in response to DbA...
  7. ncbi Gene expression profiling for understanding chemical causation of biological effects for complex mixtures: a case study on estrogens
    Amy L Filby
    School of Biosciences, The Hatherly Laboratories, University of Exeter, Prince of Wales Road, Exeter, EX4 4PS, UK
    Environ Sci Technol 41:8187-94. 2007
    ....
  8. ncbi Variability in measures of reproductive success in laboratory-kept colonies of zebrafish and implications for studies addressing population-level effects of environmental chemicals
    Gregory C Paull
    Environmental and Molecular Fish Biology Group, School of Biosciences, Hatherly Laboratories, University of Exeter, Prince of Wales Road, Exeter EX4 4PS, United Kingdom
    Aquat Toxicol 87:115-26. 2008
    ..These data demonstrate the need for high levels of replication when testing for effects of EDCs on reproductive output in the zebrafish model in an environmentally relevant ('6 x 6') breeding matrix...
  9. ncbi ELISAs for detecting vitellogenin in the fathead minnow (Pimephales promelas)-a critical analysis. Response to Mylchreest et al., Comp Biochem Physiol C 134: 251-257, 2003
    Charles R Tyler
    School of Biological and Chemical Sciences, University of Exeter, Exeter EX4 4PS, United Kingdom
    Comp Biochem Physiol C Toxicol Pharmacol 138:531-2; author reply 533-6. 2004
  10. ncbi Sexually dimorphic gene expression in the brains of mature zebrafish
    Eduarda M Santos
    School of Biosciences, University of Exeter, Prince of Wales Road, Exeter, EX4 4PS, UK
    Comp Biochem Physiol A Mol Integr Physiol 149:314-24. 2008
    ..We have demonstrated the existence of dimorphic patterns of gene expression in the brain of a sexually mature, non-mammalian, vertebrate model, with implications for studies into reproduction and chemical disruption of brain function...
  11. ncbi Accounting for differences in estrogenic responses in rainbow trout (Oncorhynchus mykiss: Salmonidae) and roach (Rutilus rutilus: Cyprinidae) exposed to effluents from wastewater treatment works
    C R Tyler
    Environmental and Molecular Fish Biology Group, Department of Biological Sciences, University of Exeter, Exeter, United Kingdom
    Environ Sci Technol 39:2599-607. 2005
    ..The nature of the estrogenic contaminants is detailed in an accompanying paper...
  12. ncbi Effects of aqueous exposure to silver nanoparticles of different sizes in rainbow trout
    Tessa M Scown
    Ecotoxicology and Aquatic Biology Research Group, Hatherly Laboratories, School of Biosciences, University of Exeter, Exeter EX4 4PS, UK
    Toxicol Sci 115:521-34. 2010
    ..However, exposure to N(10) particles was found to induce expression of cyp1a2 in the gills, suggesting a possible increase in oxidative metabolism in this tissue...