William A Sands

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. ncbi request reprint Regulating gene transcription in response to cyclic AMP elevation
    William A Sands
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, Scotland, UK
    Cell Signal 20:460-6. 2008
  2. pmc Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells
    William A Sands
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    Mol Cell Biol 26:6333-46. 2006
  3. doi request reprint Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene
    Stephen J Yarwood
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Davidson Bldg, Glasgow G12 8QQ, United Kingdom
    J Biol Chem 283:6843-53. 2008
  4. doi request reprint Exchange protein directly activated by cyclic AMP-1-regulated recruitment of CCAAT/enhancer-binding proteins to the suppressor of cytokine signaling-3 promoter
    William A Sands
    Institute for Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK
    Methods Mol Biol 809:201-14. 2012
  5. doi request reprint Priming of signal transducer and activator of transcription proteins for cytokine-triggered polyubiquitylation and degradation by the A 2A adenosine receptor
    Mohammed M A Safhi
    Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Mol Pharmacol 77:968-78. 2010
  6. ncbi request reprint Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P3
    Claire Rutherford
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Scotland, UK
    Cell Signal 17:997-1009. 2005
  7. ncbi request reprint Specific inhibition of nuclear factor-kappaB-dependent inflammatory responses by cell type-specific mechanisms upon A2A adenosine receptor gene transfer
    William A Sands
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom
    Mol Pharmacol 66:1147-59. 2004

Collaborators

  • S J Yarwood
  • John C McGrath
  • Claire Rutherford
  • Mohammed M A Safhi
  • Timothy M Palmer
  • Catherine Ledent
  • Fiona U Ord-Shrimpton
  • Jeffrey L Benovic
  • John D Pediani

Detail Information

Publications7

  1. ncbi request reprint Regulating gene transcription in response to cyclic AMP elevation
    William A Sands
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, Scotland, UK
    Cell Signal 20:460-6. 2008
    ....
  2. pmc Exchange protein activated by cyclic AMP (Epac)-mediated induction of suppressor of cytokine signaling 3 (SOCS-3) in vascular endothelial cells
    William A Sands
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, United Kingdom
    Mol Cell Biol 26:6333-46. 2006
    ..Together, these data argue for the existence of a novel cAMP/Epac/Rap1/SOCS-3 pathway for limiting IL-6 receptor signaling in ECs and illuminate a new mechanism by which cAMP may mediate its potent anti-inflammatory effects...
  3. doi request reprint Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene
    Stephen J Yarwood
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Faculty of Biomedical and Life Sciences, University of Glasgow, Davidson Bldg, Glasgow G12 8QQ, United Kingdom
    J Biol Chem 283:6843-53. 2008
    ..In summary, our findings constitute the first description of an EPAC-C/EBP pathway that can control cAMP-mediated changes in gene expression independently of protein kinase A...
  4. doi request reprint Exchange protein directly activated by cyclic AMP-1-regulated recruitment of CCAAT/enhancer-binding proteins to the suppressor of cytokine signaling-3 promoter
    William A Sands
    Institute for Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, Scotland, UK
    Methods Mol Biol 809:201-14. 2012
    ..We also describe the RNA interference strategies with which we identified a role for Epac1 and SOCS-3 in being responsible for mediating the inhibitory effect of cAMP elevation on IL-6 signaling...
  5. doi request reprint Priming of signal transducer and activator of transcription proteins for cytokine-triggered polyubiquitylation and degradation by the A 2A adenosine receptor
    Mohammed M A Safhi
    Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Mol Pharmacol 77:968-78. 2010
    ....
  6. ncbi request reprint Phosphorylation-independent internalisation and desensitisation of the human sphingosine-1-phosphate receptor S1P3
    Claire Rutherford
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Scotland, UK
    Cell Signal 17:997-1009. 2005
    ....
  7. ncbi request reprint Specific inhibition of nuclear factor-kappaB-dependent inflammatory responses by cell type-specific mechanisms upon A2A adenosine receptor gene transfer
    William A Sands
    Molecular Pharmacology Group, Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow, G12 8QQ, United Kingdom
    Mol Pharmacol 66:1147-59. 2004
    ....