I J Russell

Summary

Affiliation: University of Sussex
Country: UK

Publications

  1. pmc The location of the cochlear amplifier: spatial representation of a single tone on the guinea pig basilar membrane
    I J Russell
    School of Biological Sciences, University of Sussex, Falmer Brighton, United Kingdom
    Proc Natl Acad Sci U S A 94:2660-4. 1997
  2. pmc Sharpened cochlear tuning in a mouse with a genetically modified tectorial membrane
    Ian J Russell
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 10:215-23. 2007
  3. ncbi request reprint The development of a single frequency place in the mammalian cochlea: the cochlear resonance in the mustached bat Pteronotus parnellii
    Ian J Russell
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom
    J Neurosci 23:10971-81. 2003
  4. ncbi request reprint Synchronization of a nonlinear oscillator: processing the cf component of the echo-response signal in the cochlea of the mustached bat
    Ian J Russell
    School of Life Sciences, University of Sussex, Brighton, BN1 9QG United Kingdom
    J Neurosci 23:9508-18. 2003
  5. ncbi request reprint A deafness mutation isolates a second role for the tectorial membrane in hearing
    P Kevin Legan
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 8:1035-42. 2005
  6. ncbi request reprint A targeted deletion in alpha-tectorin reveals that the tectorial membrane is required for the gain and timing of cochlear feedback
    P K Legan
    School of Biological Sciences, The University of Sussex, Falmer, Brighton, United Kingdom
    Neuron 28:273-85. 2000
  7. doi request reprint Outer hair cell somatic, not hair bundle, motility is the basis of the cochlear amplifier
    Marcia M Mellado Lagarde
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 11:746-8. 2008
  8. pmc Frequency-dependent properties of the tectorial membrane facilitate energy transmission and amplification in the cochlea
    G P Jones
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, United Kingdom
    Biophys J 104:1357-66. 2013
  9. ncbi request reprint Origin of the bell-like dependence of the DPOAE amplitude on primary frequency ratio
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Acoust Soc Am 110:3097-106. 2001
  10. doi request reprint Multiple roles for the tectorial membrane in the active cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Hear Res 266:26-35. 2010

Collaborators

Detail Information

Publications26

  1. pmc The location of the cochlear amplifier: spatial representation of a single tone on the guinea pig basilar membrane
    I J Russell
    School of Biological Sciences, University of Sussex, Falmer Brighton, United Kingdom
    Proc Natl Acad Sci U S A 94:2660-4. 1997
    ..We estimate that the site of amplification for the 15 kHz region is restricted to a 1.25 mm length of basilar membrane centered on the 15 kHz place...
  2. pmc Sharpened cochlear tuning in a mouse with a genetically modified tectorial membrane
    Ian J Russell
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 10:215-23. 2007
    ..These findings can be attributed to a reduction in the acting mass of the tectorial membrane and reveal a new function for this structure in controlling interactions along the cochlea...
  3. ncbi request reprint The development of a single frequency place in the mammalian cochlea: the cochlear resonance in the mustached bat Pteronotus parnellii
    Ian J Russell
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom
    J Neurosci 23:10971-81. 2003
    ..At maturity, the CM has three modes for frequencies within 10 kHz of the resonance at tone onset and a single, sharply tuned mode in the ringing...
  4. ncbi request reprint Synchronization of a nonlinear oscillator: processing the cf component of the echo-response signal in the cochlea of the mustached bat
    Ian J Russell
    School of Life Sciences, University of Sussex, Brighton, BN1 9QG United Kingdom
    J Neurosci 23:9508-18. 2003
    ..The frequency responses of the CM recorded from the cochlear fovea can be accounted for through synchronization between the nonlinear oscillators responsible for the cochlear resonance and the stimulus tone...
  5. ncbi request reprint A deafness mutation isolates a second role for the tectorial membrane in hearing
    P Kevin Legan
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 8:1035-42. 2005
    ..Thus, using Tecta(Y1870C/+) mice, we have genetically isolated a second major role for the tectorial membrane in hearing: it enables the motion of the basilar membrane to optimally drive the inner hair cells at their best frequency...
  6. ncbi request reprint A targeted deletion in alpha-tectorin reveals that the tectorial membrane is required for the gain and timing of cochlear feedback
    P K Legan
    School of Biological Sciences, The University of Sussex, Falmer, Brighton, United Kingdom
    Neuron 28:273-85. 2000
    ..Thus, the tectorial membrane ensures that outer hair cells can effectively respond to basilar membrane motion and that feedback is delivered with the appropriate gain and timing required for amplification...
  7. doi request reprint Outer hair cell somatic, not hair bundle, motility is the basis of the cochlear amplifier
    Marcia M Mellado Lagarde
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Nat Neurosci 11:746-8. 2008
    ..We conclude that somatic, and not stereocilia, motility is the basis of cochlear amplification...
  8. pmc Frequency-dependent properties of the tectorial membrane facilitate energy transmission and amplification in the cochlea
    G P Jones
    School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, United Kingdom
    Biophys J 104:1357-66. 2013
    ..This prediction is confirmed by neural recordings from several frequency regions of the cochlea...
  9. ncbi request reprint Origin of the bell-like dependence of the DPOAE amplitude on primary frequency ratio
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Acoust Soc Am 110:3097-106. 2001
    ..The difference between the DPOAE recorded from guinea pigs and humans is discussed in terms of different position of the operating point of the DPOAE generating nonlinearity...
  10. doi request reprint Multiple roles for the tectorial membrane in the active cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, UK
    Hear Res 266:26-35. 2010
    ..The role of the tectorial membrane in distributing energy along the cochlear partition and how it channels this energy to the inner hair cells is described...
  11. pmc The tectorial membrane: one slice of a complex cochlear sandwich
    Guy P Richardson
    School of Life Sciences, University of Sussex, Falmer, Brighton, UK
    Curr Opin Otolaryngol Head Neck Surg 16:458-64. 2008
    ....
  12. ncbi request reprint Power amplification in the mammalian cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, UK
    Curr Biol 17:1340-4. 2007
    ..The finding also makes redundant current hypotheses of cochlear frequency sharpening and sensitization that are not based on negative damping...
  13. ncbi request reprint Properties of distortion product otoacoustic emissions and neural suppression tuning curves attributable to the tectorial membrane resonance
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom
    J Acoust Soc Am 121:337-43. 2007
    ..The emission bandpass structure is, however, likely to be generated by a combination of mechanisms with different ones dominating at different stimulus parameters...
  14. ncbi request reprint One source for distortion product otoacoustic emissions generated by low- and high-level primaries
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Brighton, United Kingdom
    J Acoust Soc Am 111:2740-8. 2002
    ....
  15. ncbi request reprint Modifications of a single saturating non-linearity account for post-onset changes in 2f1-f2 distortion product otoacoustic emission
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton, United Kingdom
    J Acoust Soc Am 112:1561-8. 2002
    ....
  16. ncbi request reprint A second, low-frequency mode of vibration in the intact mammalian cochlea
    Andrei N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom
    J Acoust Soc Am 113:1544-50. 2003
    ....
  17. ncbi request reprint Role of the tectorial membrane revealed by otoacoustic emissions recorded from wild-type and transgenic Tecta(deltaENT/deltaENT) mice
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, United Kingdom
    J Neurophysiol 91:163-71. 2004
    ..A nonlinear low-frequency resonance, revealed by nonmonotonicity of the phase behavior, was seen in the wild-type but not in Tecta(deltaENT/deltaENT) mice...
  18. ncbi request reprint Dependence of the DPOAE amplitude pattern on acoustical biasing of the cochlear partition
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    Hear Res 203:45-53. 2005
    ....
  19. ncbi request reprint A self-mixing laser-diode interferometer for measuring basilar membrane vibrations without opening the cochlea
    Andrei N Lukashkin
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    J Neurosci Methods 148:122-9. 2005
    ..The interferometer provides a viable means for making subnanometre mechanical measurements from structures in the inner ears of small mammals, where opening of the cochlea is not practicable...
  20. ncbi request reprint The voltage dependence of the mechanoelectrical transducer modifies low frequency outer hair cell electromotility in vitro
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton, UK
    Hear Res 113:133-9. 1997
    ..Following treatment of the hair bundle with BAPTA or dihydrostreptomycin, which are known to impair transduction function (Assad et al., 1991; Kroese et al., 1989), rectification of the motile response disappeared...
  21. doi request reprint The role of prestin in the generation of electrically evoked otoacoustic emissions in mice
    Markus Drexl
    University of Sussex, School of Life Sciences, Brighton, UK
    J Neurophysiol 99:1607-15. 2008
    ..We conclude that near threshold, the emissions are generated by prestin-based somatic motility...
  22. ncbi request reprint A descriptive model of the receptor potential nonlinearities generated by the hair cell mechanoelectrical transducer
    A N Lukashkin
    School of Biological Sciences, University of Sussex, Falmer, Brighton, United Kingdom
    J Acoust Soc Am 103:973-80. 1998
    ..The model also shows that there is non-monotonic growth and phase change for any spectral component, but not for the fundamental of the receptor potential...
  23. doi request reprint Prestin's role in cochlear frequency tuning and transmission of mechanical responses to neural excitation
    Marcia M Mellado Lagarde
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom
    Curr Biol 18:200-2. 2008
    ..Prestin is crucial for defining sharp and sensitive cochlear frequency tuning by reducing the sensitivity of the low-frequency tail of the tuning curve, although this necessitates a cochlear amplifier to determine the narrowly tuned tip...
  24. doi request reprint Sex Recognition through midflight mating duets in Culex mosquitoes is mediated by acoustic distortion
    Ben Warren
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    Curr Biol 19:485-91. 2009
    ..This is the first report of acoustic distortion being exploited as a sensory cue, rather than existing as an epiphenomenon...
  25. doi request reprint "Singing on the wing" as a mechanism for species recognition in the malarial mosquito Anopheles gambiae
    Cedric Pennetier
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    Curr Biol 20:131-6. 2010
    ..This is the first description of close-range mating interactions in incipient An. gambiae species...
  26. pmc The dynein-tubulin motor powers active oscillations and amplification in the hearing organ of the mosquito
    Ben Warren
    School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    Proc Biol Sci 277:1761-9. 2010
    ..If, as has been claimed for insect and vertebrate hearing organs, spontaneous oscillations epitomize amplification, then in the mosquito ear, this process is independent of mechanotransduction...