Research Topics
| M F RushworthSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Adaptive decision making and value in the anterior cingulate cortexMark E Walton
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
Neuroimage 36:T142-54. 2007..Taken together, this implies a prominent role for the ACC within a distributed network of regions that determine the dynamic value of actions and guide decision making appropriately...
Action sets and decisions in the medial frontal cortexM F S Rushworth
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
Trends Cogn Sci 8:410-7. 2004....
Components of attentional set-switchingM F S Rushworth
Department of Experimental Psychology, University of Oxford, England
Exp Psychol 52:83-98. 2005....
Learning the value of information in an uncertain worldTimothy E J Behrens
FMRIB Centre, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
Nat Neurosci 10:1214-21. 2007..Furthermore, variations in this ACC signal across the population predict variations in subject learning rates. Our results provide a formal account of how we weigh our different experiences in guiding our future actions...
Valuation and decision-making in frontal cortex: one or many serial or parallel systems?Matthew Fs Rushworth
Department of Experimental Psychology, University of Oxford, United Kingdom Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, University of Oxford, United Kingdom Electronic address
Curr Opin Neurobiol 22:946-55. 2012....
The left parietal and premotor cortices: motor attention and selectionM F S Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
Neuroimage 20:S89-100. 2003..In summary, patterns of motor impairment and recovery seen after strokes can partly be explained with reference to the roles of the parietal and premotor cortices in motor attention and selection...
General mechanisms for making decisions?Matthew F S Rushworth
Department of Experimental Psychology, University of Oxford, Oxford, UK
Curr Opin Neurobiol 19:75-83. 2009..A growing body of work even suggests analogous processes may account for behaviour outside the domain of reward-guided decision making, for example, when people and animals learn about visual and social environments...
Intention, choice, and the medial frontal cortexMatthew F S Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, England, UK
Ann N Y Acad Sci 1124:181-207. 2008..In such situations the MFC exerts an influence over how actions will be chosen by other motor regions of the brain...
Cognitive neuroscience: resolving conflict in and over the medial frontal cortexM F S Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Curr Biol 15:R54-6. 2005..Recent work casts light on how these functions are parcelled out in the medial frontal cortex...
Choice, uncertainty and value in prefrontal and cingulate cortexMatthew F S Rushworth
Department of Experimental Psychology and Centre for Functional MRI of the Brain, John Radcliffe Hospital, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Nat Neurosci 11:389-97. 2008....
Connection patterns distinguish 3 regions of human parietal cortexM F S Rushworth
Department of Experimental Psychology, University of Oxford, and Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, John Radcliffe Hospital, Oxford OX1 3UD, UK
Cereb Cortex 16:1418-30. 2006..Human parietal areas have anatomical connections resembling those of functionally related macaque parietal areas...
Attentional selection and action selection in the ventral and orbital prefrontal cortexMatthew F S Rushworth
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
J Neurosci 25:11628-36. 2005..A special contribution of PFv+o may be initial selection of behaviorally relevant stimuli...
TMS in the parietal cortex: updating representations for attention and actionM F S Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, United Kingdom
Neuropsychologia 44:2700-16. 2006..A consistent theme that runs through many reports is that of a critical contribution of parietal areas when attention or movements are re-directed and representations for attention or action must be updated...
A paradoxical role for inhibition in initiationMatthew F S Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Neuron 54:669-70. 2007....
Contrasting roles for cingulate and orbitofrontal cortex in decisions and social behaviourM F S Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Trends Cogn Sci 11:168-76. 2007..Evidence is emerging to suggest that the anterior cingulate and orbitofrontal cortex make distinct contributions to each of these aspects of decision making...
Functional organization of the medial frontal cortexMatthew F S Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Curr Opin Neurobiol 17:220-7. 2007..Evaluation of other individuals is therefore crucial for effective action selection, and some ACC regions are implicated in this process...
The effect of cingulate cortex lesions on task switching and working memoryM F S Rushworth
University of Oxford, UK
J Cogn Neurosci 15:338-53. 2003....
Components of switching intentional setMatthew F S Rushworth
Department of Experimental Psychology, University of Oxford, UK
J Cogn Neurosci 14:1139-50. 2002..Set initiation started with modulation of medial frontal ERPs and was followed by modulation over parietal electrodes. Implementation of intentional set was associated with modulation of response-related ERPs...
The left hemisphere and the selection of learned actionsM F Rushworth
Department of Experimental Psychology, University of Oxford, UK
Neuropsychologia 36:11-24. 1998..The lesions of the impaired LH group were widespread but always included the distributed systems known to be important for response selection-the dorsolateral frontal and parietal cortices, striatum, thalamus and white matter fascicles...
The attentional role of the left parietal cortex: the distinct lateralization and localization of motor attention in the human brainM F Rushworth
Wellcome Institute of Cognitive Neurology, London, UK
J Cogn Neurosci 13:698-710. 2001..The results also provide evidence concerning the importance of ventral premotor (PMv) and Broca's area in motor attention and language processes...
Attention systems and the organization of the human parietal cortexM F Rushworth
Department of Experimental Psychology, Oxford University, Oxford, OX1 3UD, United Kingdom
J Neurosci 21:5262-71. 2001..The results also suggest that the basic functional organization of the intraparietal sulcus and surrounding regions is similar in both macaque and human species...
Parietal cortex and movement. II. Spatial representationM F Rushworth
Department of Experimental Psychology, University of Oxford, UK
Exp Brain Res 117:311-23. 1997..This suggests that 5/7b/MIP does not represent the limb in simple sensory or motor coordinates but in terms of its spatial position...
Complementary localization and lateralization of orienting and motor attentionM F Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
Nat Neurosci 4:656-61. 2001..The critical area for motor attention is anterior to the one concerned with orienting, and it is lateralized to the left hemisphere in humans...
Parietal cortex and movement. I. Movement selection and reachingM F Rushworth
Department of Experimental Psychology, University of Oxford, UK
Exp Brain Res 117:292-310. 1997..Neither part of the parietal lobe appears to be important for the non-standard, non-spatial transformations of response selection...
The left parietal cortex and motor attentionM F Rushworth
Department of Experimental Psychology, University of Oxford, U K
Neuropsychologia 35:1261-73. 1997..We suggest that the well documented left hemisphere and apraxic impairment in movement sequencing is the consequence of a difficulty in shifting the focus of motor attention from one movement in a sequence to the next...
Frontal cortex and reward-guided learning and decision-makingMatthew F S Rushworth
Department of Experimental Psychology, University of Oxford, South Parks Road OX13UD, UK
Neuron 70:1054-69. 2011....
Cerebral dominance for action in the human brain: the selection of actionsN D Schluter
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Neuropsychologia 39:105-13. 2001..It is argued that the results suggest that the left hemisphere is dominant not only for speech but also for action in general...
Interference with performance of a response selection task that has no working memory component: an rTMS comparison of the dorsolateral prefrontal and medial frontal cortexK A Hadland
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
J Cogn Neurosci 13:1097-108. 2001..The difference appears to be that the DLPFC is important when selecting between competing responses or when concentrating if there is a high attentional demand, but that the MFC is only important during the response selection task...
Does the medial orbitofrontal cortex have a role in social valuation?M P Noonan
Department of Experimental Psychology, University of Oxford, South Parks Road, OX1 3UD, UK
Eur J Neurosci 31:2341-51. 2010..In summary, the double dissociation between the patterns of impairment suggest that vmPFC involvement in both decision-making and social valuation may be mediated by distinct subregions centred on mOFC and ACCg respectively...
The mental number line and the human angular gyrusS Gobel
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, England
Neuroimage 14:1278-89. 2001..The effect of angular gyrus rTMS on the number line task was specific. rTMS had no disruptive effect when delivered over another parietal region, the supramarginal gyrus, in either the left or the right hemisphere...
The contribution of distinct subregions of the ventromedial frontal cortex to emotion, social behavior, and decision makingP H Rudebeck
University of Oxford, Oxford, England
Cogn Affect Behav Neurosci 8:485-97. 2008....
Specialisation within the prefrontal cortex: the ventral prefrontal cortex and associative learningR E Passingham
Department of Experimental Psychology, University of Oxford, UK
Exp Brain Res 133:103-13. 2000..On the basis of the existing anatomical and electrophysiological data, it is argued that the prefrontal cortex is the only area that can represent cues, responses and outcomes...
The effect of cingulate lesions on social behaviour and emotionK A Hadland
Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Neuropsychologia 41:919-31. 2003..The results are consistent with a cingulate role in social behaviour and emotion...
Neural correlates of visuomotor associations. Spatial rules compared with arbitrary rulesI Toni
Wellcome Department of Cognitive Neurology, Institute of Neurology, University College, London, 12 Queen Square, London WC1N 3BG, UK
Exp Brain Res 141:359-69. 2001..The results suggest that visual information can flow through the dorsal system to determine how actions are performed, but that fronto-striatal loops are involved in specifying which action should be performed in the current context...
Role of the human medial frontal cortex in task switching: a combined fMRI and TMS studyM F S Rushworth
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
J Neurophysiol 87:2577-92. 2002..Second, the VS rTMS results suggest that just because an area is activated in two paradigms does not mean that it plays the same essential role in both cases...
Anatomical connectivity of the subgenual cingulate region targeted with deep brain stimulation for treatment-resistant depressionH Johansen-Berg
Centre for Functional MRI of the Brain, University of Oxford, Oxford OX3 9DU, UK
Cereb Cortex 18:1374-83. 2008..We hypothesize that the subgenual region with greatest connectivity across the distributed network described here may prove most effective...
Weighing up the benefits of work: behavioral and neural analyses of effort-related decision makingM E Walton
Department of Experimental Psychology, South Parks Road, Oxford, UK
Neural Netw 19:1302-14. 2006..We suggest that top-down signals from ACC to nucleus accumbens (NAc) and/or midbrain DA cells may be vital for overcoming effort-related response costs...
The mesocortical dopamine projection to anterior cingulate cortex plays no role in guiding effort-related decisionsM E Walton
Department of Experimental Psychology, University of Oxford, Oxford, England
Behav Neurosci 119:323-8. 2005..These results imply that the DA projection to ACC is not involved in guiding effort-related decisions...
Probabilistic diffusion tractography with multiple fibre orientations: What can we gain?T E J Behrens
Oxford Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, Oxford, UK
Neuroimage 34:144-55. 2007..We show that multi-fibre tractography offers significant advantages in sensitivity when tracking non-dominant fibre populations, but does not dramatically change tractography results for the dominant pathways...
Changes in connectivity profiles define functionally distinct regions in human medial frontal cortexH Johansen-Berg
Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
Proc Natl Acad Sci U S A 101:13335-40. 2004..This finding demonstrates a strong relationship between structure and function in medial frontal cortex and offers a strategy for testing such correspondences elsewhere in the brain...
Organization of action sequences and the role of the pre-SMASteve W Kennerley
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
J Neurophysiol 91:978-93. 2004..Control experiments revealed such effects were not present when rTMS was applied over the left dorsal premotor cortex...
Towards understanding language organisation in the brain using fMRIP M Matthews
Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, John Radcliffe Hospital, Oxford, United Kingdom
Hum Brain Mapp 18:239-47. 2003..We describe how TMS combined with fMRI has confirmed a role for the left inferior frontal cortex in semantic processing...
Separate value comparison and learning mechanisms in macaque medial and lateral orbitofrontal cortexM P Noonan
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
Proc Natl Acad Sci U S A 107:20547-52. 2010..Contrary to axiomatic assumptions of decision theory, the mOFC-lesioned animals' value comparisons were no longer independent of irrelevant alternatives...
A role for the macaque anterior cingulate gyrus in social valuationP H Rudebeck
Department of Experimental Psychology, University of Oxford, Oxford, OX1 3UD, UK
Science 313:1310-2. 2006..These results suggest that damage to the anterior cingulate gyrus may be the cause of changes in social interaction seen after frontal lobe damage...
The anterior cingulate and reward-guided selection of actionsK A Hadland
Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, United Kingdom
J Neurophysiol 89:1161-4. 2003....
Impulsive choice in hippocampal but not orbitofrontal cortex-lesioned rats on a nonspatial decision-making maze taskT Y Mariano
Department of Experimental Psychology, University of Oxford, Oxford, UK
Eur J Neurosci 30:472-84. 2009..The impulsivity in HPC-lesioned rats may reflect impaired temporal information processing, and emphasizes a role for the hippocampus beyond the spatial domain...
Differential involvement of serotonin and dopamine systems in cost-benefit decisions about delay or effortF Denk
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
Psychopharmacology (Berl) 179:587-96. 2005..While dopaminergic systems were required for decisions about both effort and delay, serotonergic systems were only needed for the latter...
Functional specialization of the primate frontal cortex during decision makingDaeyeol Lee
Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
J Neurosci 27:8170-3. 2007..These cortical areas are also likely to contribute to decision making in a social context...
Individual differences in white-matter microstructure reflect variation in functional connectivity during choiceErie Dell Boorman
Centre for Functional MRI of the Brain, University of Oxford, Oxford OX3 9DU, United Kingdom
Curr Biol 17:1426-31. 2007..These findings demonstrate a relationship between individual differences in functional and structural connectivity within human brain networks central to action choice...
Imaging causal interactions during sensorimotor processingJacinta O'Shea
Department of Experimental Psychology, University of Oxford, Oxford, UK
Cortex 44:598-608. 2008..We discuss the theoretical advantages of each technique, illustrated by examples from the literature, and highlight the potential of these approaches to provide novel insights into the neural bases of action control...
Subsecond changes in top down control exerted by human medial frontal cortex during conflict and action selection: a combined transcranial magnetic stimulation electroencephalography studyPaul C J Taylor
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
J Neurosci 27:11343-53. 2007..dMFC has a direct causal role in resolving conflict during action selection, and the mechanism involves the top-down modulation of primary motor cortical activity...
Distinct contributions of frontal areas to emotion and social behaviour in the ratPeter H Rudebeck
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Eur J Neurosci 26:2315-26. 2007..Although the relationship between changes in social interaction and decision-making after ACC lesions is unclear, OFC impairments in emotionality were correlated with increased impulsive choice...
Functional specificity of human premotor-motor cortical interactions during action selectionJacinta O'Shea
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Eur J Neurosci 26:2085-95. 2007..Such interactions are temporally, anatomically and functionally specific, and have a causal role in choosing which movement to make...
Diffusion-weighted imaging tractography-based parcellation of the human lateral premotor cortex identifies dorsal and ventral subregions with anatomical and functional specializationsValentina Tomassini
Centre for Functional MRI of the Brain, University of Oxford, Oxford OX3 9DU, United Kingdom
J Neurosci 27:10259-69. 2007....
The role of rat medial frontal cortex in effort-based decision makingMark E Walton
Department of Experimental Psychology, Oxford, OX1 3UD, United Kingdom
J Neurosci 22:10996-1003. 2002..These results imply that medial frontal cortex is important for allowing the animal to put in more work to obtain greater rewards...
Semantic processing in the left inferior prefrontal cortex: a combined functional magnetic resonance imaging and transcranial magnetic stimulation studyJoseph T Devlin
FMRIB Center, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Headington, UK
J Cogn Neurosci 15:71-84. 2003..In addition, the findings go beyond simply establishing a correlation between semantic processing and activation in the LIPC and demonstrate that a transient disruption of processing selectively interfered with semantic processing...
Functional specialization within medial frontal cortex of the anterior cingulate for evaluating effort-related decisionsMark E Walton
Department of Experimental Psychology, Oxford, OX1 3UD, United Kingdom
J Neurosci 23:6475-9. 2003..This double dissociation indicates that the ACC is the important region within the MFC when evaluating how much effort to expand for a specific reward...
Cognitive neuroscience: acting on numbersSilke M Gobel
Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Curr Biol 14:R517-9. 2004..The parietal cortex is a central part of the brain's system for representing numbers and magnitudes. Activity in the parietal cortex might reflect number representation or actions made in response to the numbers...
Category-related activation for written words in the posterior fusiform is task specificJoseph T Devlin
Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical Neurology, John Radcliffe Hospital, University of Oxford, Headley Way, Headington, Oxford OX3 9DU, UK
Neuropsychologia 43:69-74. 2005..The results suggest that category-related activation in the posterior fusiform gyri can be driven either "bottom-up" by visual processing of images or "top-down" by word processing...
Interactions between decision making and performance monitoring within prefrontal cortexMark E Walton
Department of Experimental Psychology, South Parks Road, Oxford, OX1 3UD, England, UK
Nat Neurosci 7:1259-65. 2004..These results indicate that the neural mechanisms underlying the way we assess the consequences of choices differ depending on whether we are told what to do or are able to exercise our volition...
Response-selection-related parietal activation during number comparisonSilke M Gobel
Department of Experimental Psychology, University of Oxford, OX1 3UD, UK
J Cogn Neurosci 16:1536-51. 2004..In this respect, the representation of magnitude in the human IPS may be similar to the representation of magnitude in other nonhuman primates...
Parietal rTMS disrupts the initiation but not the execution of on-line adjustments to a perturbation of object sizeScott Glover
University of Oxford
J Cogn Neurosci 17:124-36. 2005..The implications of these results for current views of on-line control are discussed...
Effects of an orientation illusion on motor performance and motor imageryScott Glover
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
Exp Brain Res 166:17-22. 2005..The results are discussed in terms of the visual processing and representation of real and imagined actions...
Quantitative investigation of connections of the prefrontal cortex in the human and macaque using probabilistic diffusion tractographyPaula L Croxson
Centre for Functional Magnetic Resonance Imaging of the Brain, Department of Clinical, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom
J Neurosci 25:8854-66. 2005..Some limitations to the DWI approach were apparent; the high diffusion anisotropy in the corpus callosum made it difficult to compare connection probability values in the adjacent cingulate region...
Combining correlation and interference methods in the human brain. Focus on "Cortico-cortical interactions in spatial attention: A combined ERP/TMS study"Paul C J Taylor
J Neurophysiol 95:2731-2. 2006
FEF TMS affects visual cortical activityPaul C J Taylor
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Cereb Cortex 17:391-9. 2007..The results show that the human FEF has a causal influence over the modulation of visual activity in posterior areas when attention is being allocated...
Optimal decision making and the anterior cingulate cortexSteven W Kennerley
Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Nat Neurosci 9:940-7. 2006..These data suggest that the ACC is essential for learning the value of actions...
Separate neural pathways process different decision costsPeter H Rudebeck
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Nat Neurosci 9:1161-8. 2006..Although the existence of two systems is not predicted by economic accounts of decision making, our results suggest that delay and effort may exert distinct influences on decision making...
Calculating the cost of acting in frontal cortexMark E Walton
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
Ann N Y Acad Sci 1104:340-56. 2007..Taken together, this indicates that there may be dissociable pathways in the frontal lobe for managing different types of response cost and for gathering social information...
Functionally specific reorganization in human premotor cortexJacinta O'Shea
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, United Kingdom
Neuron 54:479-90. 2007..Subsequent TMS of the reorganized right PMd did disrupt performance. Thus, this pattern of functional reorganization has a causal role in preserving behavior after neuronal challenge...
The role of ipsilateral premotor cortex in hand movement after strokeHeidi Johansen-Berg
Centre for Functional Magnetic Resonance Imaging of the Brain, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
Proc Natl Acad Sci U S A 99:14518-23. 2002....
