C P Rubbi

Summary

Affiliation: University of York
Country: UK

Publications

  1. ncbi request reprint Analysis of nucleotide excision repair by detection of single-stranded DNA transients
    C P Rubbi
    YCR P53 Research Group, Department of Biology, University of York, York YO10 5DD, UK
    Carcinogenesis 22:1789-96. 2001
  2. pmc p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage
    Carlos P Rubbi
    Department of Biology, University of York, York YO10 5DD, UK
    EMBO J 22:975-86. 2003
  3. pmc Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses
    Carlos P Rubbi
    YCR P53 Research Group, Department of Biology, University of York, York YO10 5DD, UK
    EMBO J 22:6068-77. 2003
  4. ncbi request reprint Use of density perturbation to isolate immunologically distinct populations of cells
    D Patel
    Department of Biology, University of Essex, Colchester, England, UK
    J Immunol Methods 163:241-51. 1993
  5. ncbi request reprint p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress
    M Jiang
    YCR P53 Research Group, Department of Biology, University of York, YO10 5DD, UK
    Oncogene 20:5449-58. 2001
  6. ncbi request reprint p53--guardian of a genome's guardian?
    Carlos P Rubbi
    YCR p53 Laboratory, Biology Department, University of York, York YO10 5DD, UK
    Cell Cycle 2:20-1. 2003
  7. ncbi request reprint The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage
    Andrei L Okorokov
    YCR P53 Research Group, Department of Biology, University of York, York, YO10 5DD, UK
    Oncogene 21:356-67. 2002

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Analysis of nucleotide excision repair by detection of single-stranded DNA transients
    C P Rubbi
    YCR P53 Research Group, Department of Biology, University of York, York YO10 5DD, UK
    Carcinogenesis 22:1789-96. 2001
    ..Thus, assembled repair sites can be detected even when they may not lead to complete resolution of the DNA lesion. Using this approach, we show that repair helicase-deficient cells differ from endonuclease-deficient cells...
  2. pmc p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage
    Carlos P Rubbi
    Department of Biology, University of York, York YO10 5DD, UK
    EMBO J 22:975-86. 2003
    ..We demonstrate here that p53 is also a fundamental component of DNA repair, playing a direct role in rectifying DNA damage...
  3. pmc Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses
    Carlos P Rubbi
    YCR P53 Research Group, Department of Biology, University of York, York YO10 5DD, UK
    EMBO J 22:6068-77. 2003
    ..Our model integrates all known p53-inducing agents and also explains cell cycle-related variations in p53 levels which correlate with established phases of nucleolar assembly/disassembly through the cell cycle...
  4. ncbi request reprint Use of density perturbation to isolate immunologically distinct populations of cells
    D Patel
    Department of Biology, University of Essex, Colchester, England, UK
    J Immunol Methods 163:241-51. 1993
    ..These results indicate the potential for separation of different subpopulations of cells on the basis of the immunological identity of the surface of cells using density perturbation methods involving antibody coated-density particles...
  5. ncbi request reprint p53 binds the nuclear matrix in normal cells: binding involves the proline-rich domain of p53 and increases following genotoxic stress
    M Jiang
    YCR P53 Research Group, Department of Biology, University of York, YO10 5DD, UK
    Oncogene 20:5449-58. 2001
    ..We discuss our observations in relation to the ability of p53 to facilitate DNA repair and also review evidence indicating that matrix-bound p53 in SV40-transformed cells may facilitate the transforming potential of SV40 large T antigen...
  6. ncbi request reprint p53--guardian of a genome's guardian?
    Carlos P Rubbi
    YCR p53 Laboratory, Biology Department, University of York, York YO10 5DD, UK
    Cell Cycle 2:20-1. 2003
  7. ncbi request reprint The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage
    Andrei L Okorokov
    YCR P53 Research Group, Department of Biology, University of York, York, YO10 5DD, UK
    Oncogene 21:356-67. 2002
    ..Our results indicate that the dynamic interaction of p53 with the nuclear matrix has to be considered for a full understanding of the mechanisms of the p53-mediated cellular response to DNA damage...