S J Royle

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc The cellular functions of clathrin
    S J Royle
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom
    Cell Mol Life Sci 63:1823-32. 2006
  2. pmc Clathrin is required for the function of the mitotic spindle
    Stephen J Royle
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nature 434:1152-7. 2005
  3. ncbi request reprint Constitutive cycling: a general mechanism to regulate cell surface proteins
    Stephen J Royle
    Division of Neurobiology, MRC Laboratory of Molecular Biology, Cambridge, UK
    Bioessays 25:39-46. 2003
  4. pmc Trimerisation is important for the function of clathrin at the mitotic spindle
    Stephen J Royle
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    J Cell Sci 119:4071-8. 2006
  5. pmc Clathrin-mediated endocytosis: the physiological mechanism of vesicle retrieval at hippocampal synapses
    Björn Granseth
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK
    J Physiol 585:681-6. 2007
  6. ncbi request reprint Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses
    Björn Granseth
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom
    Neuron 51:773-86. 2006
  7. pmc Endocytosis at the synaptic terminal
    Stephen J Royle
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    J Physiol 553:345-55. 2003
  8. ncbi request reprint P2X receptor trafficking in neurons is subunit specific
    Laura K Bobanovic
    Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom
    J Neurosci 22:4814-24. 2002
  9. ncbi request reprint Identification of a non-canonical tyrosine-based endocytic motif in an ionotropic receptor
    Stephen J Royle
    Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, United Kingdom
    J Biol Chem 277:35378-85. 2002
  10. ncbi request reprint Non-canonical YXXGPhi endocytic motifs: recognition by AP2 and preferential utilization in P2X4 receptors
    Stephen J Royle
    Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK
    J Cell Sci 118:3073-80. 2005

Collaborators

Detail Information

Publications10

  1. pmc The cellular functions of clathrin
    S J Royle
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom
    Cell Mol Life Sci 63:1823-32. 2006
    ....
  2. pmc Clathrin is required for the function of the mitotic spindle
    Stephen J Royle
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    Nature 434:1152-7. 2005
    ..The importance of clathrin for normal mitosis may be relevant to understanding human cancers that involve gene fusions of clathrin heavy chain...
  3. ncbi request reprint Constitutive cycling: a general mechanism to regulate cell surface proteins
    Stephen J Royle
    Division of Neurobiology, MRC Laboratory of Molecular Biology, Cambridge, UK
    Bioessays 25:39-46. 2003
    ..This review discusses the molecular mechanisms of constitutive cycling, its regulation by extracellular agents such as hormones and its misregulation in disease states...
  4. pmc Trimerisation is important for the function of clathrin at the mitotic spindle
    Stephen J Royle
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
    J Cell Sci 119:4071-8. 2006
    ....
  5. pmc Clathrin-mediated endocytosis: the physiological mechanism of vesicle retrieval at hippocampal synapses
    Björn Granseth
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, UK
    J Physiol 585:681-6. 2007
    ..These observations indicate that clathrin-mediated endocytosis is the major, if not exclusive, mechanism of retrieval in small hippocampal synapses...
  6. ncbi request reprint Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses
    Björn Granseth
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, United Kingdom
    Neuron 51:773-86. 2006
    ..These results indicate that clathrin-mediated endocytosis is the major, if not exclusive, mechanism of vesicle retrieval after physiological stimuli...
  7. pmc Endocytosis at the synaptic terminal
    Stephen J Royle
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
    J Physiol 553:345-55. 2003
    ..Key aims for the future are to identify the molecules underlying different mechanisms of endocytosis at the synapse and the signals that select between them...
  8. ncbi request reprint P2X receptor trafficking in neurons is subunit specific
    Laura K Bobanovic
    Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom
    J Neurosci 22:4814-24. 2002
    ..P2X receptors acted presynaptically to enhance the release of glutamate, suggesting that the regulated cycling of P2X4-containing receptors might provide a mechanism for modulation of synaptic transmission...
  9. ncbi request reprint Identification of a non-canonical tyrosine-based endocytic motif in an ionotropic receptor
    Stephen J Royle
    Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, United Kingdom
    J Biol Chem 277:35378-85. 2002
    ..Similar motifs are present in other receptors and may be important for the control of their functional expression...
  10. ncbi request reprint Non-canonical YXXGPhi endocytic motifs: recognition by AP2 and preferential utilization in P2X4 receptors
    Stephen J Royle
    Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK
    J Cell Sci 118:3073-80. 2005
    ..These data demonstrate that the family of potential tyrosine-based endocytic signals must be expanded to include motifs with an additional glycine at Y+3 (YXXGPhi)...