P S Rowe

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
    P S Rowe
    Centre for Molecular Osteo Renal Research, Department of Biochemistry and Molecular Biology, Royal Free and University College Medical School, Hampstead, London, United Kingdom
    Genomics 67:54-68. 2000
  2. ncbi The role of the PHEX gene (PEX) in families with X-linked hypophosphataemic rickets
    P S Rowe
    University of London, Royal Free Hospital School of Medicine, Department of Biochemistry and Molecular Biology, Hampstead, UK
    Curr Opin Nephrol Hypertens 7:367-76. 1998
  3. ncbi Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14
    G T Gillett
    MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London
    Ann Hum Genet 60:201-11. 1996
  4. ncbi Distribution of mutations in the PEX gene in families with X-linked hypophosphataemic rickets (HYP)
    P S Rowe
    Department of Medicine, University College London, Middlesex Hospital, UK
    Hum Mol Genet 6:539-49. 1997
  5. ncbi Fine structure mapping of the human X-linked hypophosphatemic rickets gene locus
    M J Econs
    Department of Medicine, Sarah W Stedman Center for Nutritional Studies, Duke University Medical Center, Durham, North Carolina 27710
    J Clin Endocrinol Metab 79:1351-4. 1994
  6. ncbi Refining the genetic map for the region flanking the X-linked hypophosphataemic rickets locus (Xp22.1-22.2)
    P S Rowe
    Middlesex Hospital, London, UK
    Hum Genet 93:291-4. 1994
  7. ncbi Genomic organization of the human PEX gene mutated in X-linked dominant hypophosphatemic rickets
    F Francis
    , Berlin, Germany
    Genome Res 7:573-85. 1997
  8. ncbi A PHEX gene mutation is responsible for adult-onset vitamin D-resistant hypophosphatemic osteomalacia: evidence that the disorder is not a distinct entity from X-linked hypophosphatemic rickets
    M J Econs
    Department of Medicine, Indiana University, Indianapolis 46202, USA
    J Clin Endocrinol Metab 83:3459-62. 1998

Collaborators

  • M J Econs
  • D F Barker
  • F Francis
  • G T Gillett
  • T Meitinger
  • C Oudet
  • S Klages
  • R Reinhardt
  • C Steffens
  • B Lorenz
  • S Hennig
  • H Lehrach
  • O Brandau
  • T M Strom
  • K Borzym
  • K L Mohnike
  • T Pohl
  • M Cagnoli
  • S Povey
  • C M Casimir
  • M F Fox

Detail Information

Publications8

  1. ncbi MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia
    P S Rowe
    Centre for Molecular Osteo Renal Research, Department of Biochemistry and Molecular Biology, Royal Free and University College Medical School, Hampstead, London, United Kingdom
    Genomics 67:54-68. 2000
    ..Evidence is also presented for the tumor secretion of clusterin (HGMW-approved symbol CLU) and its possible role as a cytotoxic factor in one of the OHO patients described...
  2. ncbi The role of the PHEX gene (PEX) in families with X-linked hypophosphataemic rickets
    P S Rowe
    University of London, Royal Free Hospital School of Medicine, Department of Biochemistry and Molecular Biology, Hampstead, UK
    Curr Opin Nephrol Hypertens 7:367-76. 1998
    ..The fact that the PHEX gene codes for a Zn metallopeptidase raises new and intriguing questions, and adds new momentum to the research on diseases of bone mineral metabolism...
  3. ncbi Mapping of human non-muscle type cofilin (CFL1) to chromosome 11q13 and muscle-type cofilin (CFL2) to chromosome 14
    G T Gillett
    MRC Human Biochemical Genetics Unit, Galton Laboratory, University College London
    Ann Hum Genet 60:201-11. 1996
    ..We have identified human muscle-type cofilin sequences by comparison of human expressed sequence tags with M-type cofilins of other species and we have mapped the human M-type cofilin, CFL2, to chromosome 14...
  4. ncbi Distribution of mutations in the PEX gene in families with X-linked hypophosphataemic rickets (HYP)
    P S Rowe
    Department of Medicine, University College London, Middlesex Hospital, UK
    Hum Mol Genet 6:539-49. 1997
    ..The wide range of mutations that align with regions required for protease activity in NEP suggests that PEX also functions as a protease, and may act by processing factor(s) involved in bone mineral metabolism...
  5. ncbi Fine structure mapping of the human X-linked hypophosphatemic rickets gene locus
    M J Econs
    Department of Medicine, Sarah W Stedman Center for Nutritional Studies, Duke University Medical Center, Durham, North Carolina 27710
    J Clin Endocrinol Metab 79:1351-4. 1994
    ..The HYP gene is located in the 350- to 650-kilobase region between DXS365 and DXS1683. These results will provide a basis for the isolation of candidate genes from the region...
  6. ncbi Refining the genetic map for the region flanking the X-linked hypophosphataemic rickets locus (Xp22.1-22.2)
    P S Rowe
    Middlesex Hospital, London, UK
    Hum Genet 93:291-4. 1994
    ..Combining the genetic and physical data, we are able to propose the following gene marker order: Xptel-DXS43-DXS197-DXS999-DXS443-[(DXS3 65-AFM163yh2), HYP]-DXS274-DXS41-Xcen...
  7. ncbi Genomic organization of the human PEX gene mutated in X-linked dominant hypophosphatemic rickets
    F Francis
    , Berlin, Germany
    Genome Res 7:573-85. 1997
  8. ncbi A PHEX gene mutation is responsible for adult-onset vitamin D-resistant hypophosphatemic osteomalacia: evidence that the disorder is not a distinct entity from X-linked hypophosphatemic rickets
    M J Econs
    Department of Medicine, Indiana University, Indianapolis 46202, USA
    J Clin Endocrinol Metab 83:3459-62. 1998
    ....