J P Roiser

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Serotonin transporter genotype differentially modulates neural responses to emotional words following tryptophan depletion in patients recovered from depression and healthy volunteers
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    J Psychopharmacol 26:1434-42. 2012
  2. pmc Cognitive mechanisms of treatment in depression
    Jonathan P Roiser
    UCL Institute of Cognitive Neuroscience, London, UK
    Neuropsychopharmacology 37:117-36. 2012
  3. pmc Adaptive and aberrant reward prediction signals in the human brain
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    Neuroimage 50:657-64. 2010
  4. pmc The effects of tryptophan depletion on neural responses to emotional words in remitted depression
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, United Kingdom
    Biol Psychiatry 66:441-50. 2009
  5. pmc Do patients with schizophrenia exhibit aberrant salience?
    J P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    Psychol Med 39:199-209. 2009
  6. pmc A genetically mediated bias in decision making driven by failure of amygdala control
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, UK
    J Neurosci 29:5985-91. 2009
  7. pmc Hot and cold cognition in unmedicated depressed subjects with bipolar disorder
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    Bipolar Disord 11:178-89. 2009
  8. doi request reprint Effects of age and MAOA genotype on the neural processing of social rejection
    C L Sebastian
    Clinical, Educational and Health Psychology, Division of Psychology and Language Sciences, University College London, London, UK
    Genes Brain Behav 9:628-37. 2010
  9. pmc Emotion-induced retrograde amnesia is determined by a 5-HTT genetic polymorphism
    Bryan A Strange
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, London WC1N 3BG, United Kingdom
    J Neurosci 28:7036-9. 2008
  10. pmc The effect of acute tryptophan depletion on the neural correlates of emotional processing in healthy volunteers
    Jonathan P Roiser
    Department of Imaging Neuroscience, Institute of Neurology, London, UK
    Neuropsychopharmacology 33:1992-2006. 2008

Detail Information

Publications15

  1. pmc Serotonin transporter genotype differentially modulates neural responses to emotional words following tryptophan depletion in patients recovered from depression and healthy volunteers
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    J Psychopharmacol 26:1434-42. 2012
    ..However, this interpretation is complicated by our failure to replicate previous findings of increased negative mood following tryptophan depletion...
  2. pmc Cognitive mechanisms of treatment in depression
    Jonathan P Roiser
    UCL Institute of Cognitive Neuroscience, London, UK
    Neuropsychopharmacology 37:117-36. 2012
    ..However, further research is required to ascertain whether negative processing biases will be useful in predicting, detecting, and treating depression, and hence in preventing a chronic, relapsing course of illness...
  3. pmc Adaptive and aberrant reward prediction signals in the human brain
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    Neuroimage 50:657-64. 2010
    ..The results are discussed in terms of their implications for different theories of associative learning...
  4. pmc The effects of tryptophan depletion on neural responses to emotional words in remitted depression
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AR, United Kingdom
    Biol Psychiatry 66:441-50. 2009
    ..We used acute tryptophan depletion (ATD) to investigate the effect of temporarily reducing brain serotonin synthesis on neural and behavioral responses to emotional stimuli in remitted MDD subjects (rMDD) and healthy control subjects...
  5. pmc Do patients with schizophrenia exhibit aberrant salience?
    J P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    Psychol Med 39:199-209. 2009
    ..To test this hypothesis we investigated whether patients with schizophrenia showed impaired learning of task-relevant stimulus-reinforcement associations in the presence of distracting task-irrelevant cues...
  6. pmc A genetically mediated bias in decision making driven by failure of amygdala control
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, London WC1N 3AR, UK
    J Neurosci 29:5985-91. 2009
    ..These data suggest that genetically mediated differences in prefrontal-amygdala interactions underpin interindividual differences in economic decision making...
  7. pmc Hot and cold cognition in unmedicated depressed subjects with bipolar disorder
    Jonathan P Roiser
    Institute of Cognitive Neuroscience, University College London, London, UK
    Bipolar Disord 11:178-89. 2009
    ..We addressed this issue by examining cognitive performance in a group of unmedicated, currently depressed subjects with BD...
  8. doi request reprint Effects of age and MAOA genotype on the neural processing of social rejection
    C L Sebastian
    Clinical, Educational and Health Psychology, Division of Psychology and Language Sciences, University College London, London, UK
    Genes Brain Behav 9:628-37. 2010
    ..The data suggest continued functional development of the circuitry underlying the processing of social rejection between adolescence and adulthood, and show that the effects of MAOA genotype on neural responses may vary with age...
  9. pmc Emotion-induced retrograde amnesia is determined by a 5-HTT genetic polymorphism
    Bryan A Strange
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, London WC1N 3BG, United Kingdom
    J Neurosci 28:7036-9. 2008
    ..The findings indicate a critical role for the serotonin system in emotion-mediated memory disruption...
  10. pmc The effect of acute tryptophan depletion on the neural correlates of emotional processing in healthy volunteers
    Jonathan P Roiser
    Department of Imaging Neuroscience, Institute of Neurology, London, UK
    Neuropsychopharmacology 33:1992-2006. 2008
    ..These data suggest that 5-HT may play an important role in mediating automatic negative attentional biases in major depression, as well as resilience against negative distracting stimuli in never-depressed individuals...
  11. pmc Encoding of marginal utility across time in the human brain
    Alex Pine
    Wellcome Trust Centre for Neuroimaging, London, United Kingdom
    J Neurosci 29:9575-81. 2009
    ..Our data support an integrative architecture for decision making, revealing the neural representation of distinct subcomponents of value that may contribute to impulsivity and decisiveness...
  12. pmc Cognitive heterogeneity in schizophrenia
    Eileen M Joyce
    UCL Institute of Neurology, London, UK
    Curr Opin Psychiatry 20:268-72. 2007
    ....
  13. pmc The effects of acute tryptophan depletion and serotonin transporter polymorphism on emotional processing in memory and attention
    Jonathan P Roiser
    Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge, UKInstitute of Neurology, Queen Square House, London, UK
    Int J Neuropsychopharmacol 10:449-61. 2007
    ....
  14. pmc Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion
    Jonathan P Roiser
    Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK, and Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA
    Neuropsychopharmacology 31:2264-72. 2006
    ....
  15. doi request reprint Reward and punishment processing in depression
    Neir Eshel
    UCL Institute of Cognitive Neuroscience, University College London, London, United Kingdom
    Biol Psychiatry 68:118-24. 2010
    ..Combining these approaches--as well as molecular and behavioral work in animals--provides great promise for furthering our understanding of this common and debilitating disease...