Robert D Rogers
Affiliation: University of Oxford
- The roles of dopamine and serotonin in decision making: evidence from pharmacological experiments in humansRobert D Rogers
Department of Experimental Psychology, University of Oxford, Oxford, Oxfordshire, UK
Neuropsychopharmacology 36:114-32. 2011....
- Systemic administration of 8-OH-DPAT and eticlopride, but not SCH23390, alters loss-chasing behavior in the ratRobert D Rogers
Department of Psychiatry, University of Oxford, Oxford, UK
Neuropsychopharmacology 38:1094-104. 2013..However, our data provide the first experimental demonstration that 5-HT1A and D2, but not D1, receptor activity influence a behavioral analog of loss-chasing in rats...
- The effects of low doses of delta-9 tetrahydrocannabinol on reinforcement processing in the risky decision-making of young healthy adultsRobert D Rogers
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
Neuropsychopharmacology 32:417-28. 2007..These results suggest that THC mediates specific motivational processes and the processing of reinforcement cues during risky choice, perhaps reflecting altered CB1 receptor or catecholamine activity within corticolimbic pathways...
- Recent research on impulsivity in individuals with drug use and mental health disorders: implications for alcoholismRobert D Rogers
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
Alcohol Clin Exp Res 34:1319-33. 2010....
- Tryptophan depletion alters the decision-making of healthy volunteers through altered processing of reward cuesRobert D Rogers
University Department of Psychiatry, University of Oxford, UK
Neuropsychopharmacology 28:153-62. 2003..It is possible that such a change in the cognition mediating human choice is one mechanism associated with the onset and maintenance of anhedonia and lowered mood in psychiatric illness...
- Effects of beta-adrenoceptor blockade on components of human decision-makingR D Rogers
University Department of Psychiatry, Warneford Hospital, Oxford, OX3 7JX, United Kingdom
Psychopharmacology (Berl) 172:157-64. 2004..In this study, we investigated the possible role of noradrenaline (NA)...
- Effects of tryptophan depletion on the performance of an iterated Prisoner's Dilemma game in healthy adultsRichard M Wood
University Department of Psychiatry, University of Oxford, Oxford, UK
Neuropsychopharmacology 31:1075-84. 2006....
- How psychological symptoms relate to different motivations for gambling: an online study of internet gamblersJoanne Lloyd
Oxford University Department of Psychiatry, Oxford, United Kingdom
Biol Psychiatry 68:733-40. 2010..Thus, motivations constitute important mechanisms linking mood fluctuations and gambling. However, little is known about how different kinds of affective disturbance, such as mood elevation and dysphoria, motivate gambling behavior...
- Low doses of delta-9 tetrahydrocannabinol (THC) have divergent effects on short-term spatial memory in young, healthy adultsPetra Makela
University Department of Psychiatry, University of Oxford, Warneford Hospital, UK
Neuropsychopharmacology 31:462-70. 2006....
- Altered emotional decision-making in prisoners with borderline personality disorderTim Kirkpatrick
University Department of Psychiatry, Warneford Hospital, Oxford, UK
J Pers Disord 21:243-61. 2007....
- The role of serotonin in nonnormative risky choice: the effects of tryptophan supplements on the "reflection effect" in healthy adult volunteersSusannah E Murphy
University of Oxford, United Kingdom
J Cogn Neurosci 21:1709-19. 2009..We conclude that serotonin activity plays a significant role in nonnormative risky decision-making under conditions of uncertainty...
- Neuropsychological function in ecstasy users: a study controlling for polydrug useJonathan P Roiser
Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Box 189, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 2QQ, UK
Psychopharmacology (Berl) 189:505-16. 2007..However, few of those studies controlled adequately for non-ecstasy illicit drug use...
- The effect of polymorphism at the serotonin transporter gene on decision-making, memory and executive function in ecstasy users and controlsJonathan P Roiser
Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke s Hospital, Box 189, Hills Road, Cambridge, CB2 2QQ, UK
Psychopharmacology (Berl) 188:213-27. 2006..One reason for such inconsistency might be interindividual variance in vulnerability to the deleterious effects of ecstasy due to a number of factors, both genetic and environmental...
- Serotonergic activity influences the cognitive appraisal of close intimate relationships in healthy adultsAmy C Bilderbeck
Department of Experimental Psychology, Oxford University, Oxford, United Kingdom
Biol Psychiatry 69:720-5. 2011..Here, we used tryptophan depletion in healthy adults to investigate the role of serotonin in the cognitive appraisal of close personal relationships...
- Knowing when to stop: the brain mechanisms of chasing lossesDaniel K Campbell-Meiklejohn
Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom
Biol Psychiatry 63:293-300. 2008..Continued gambling to recover previous losses ("loss-chasing") is central to pathological gambling. However, very little is known about the neural mechanisms that mediate this behavior...
- Altered risk-aversion and risk-seeking behavior in bipolar disorderRebecca A Chandler
Department of Psychiatry, University of Oxford, Oxford, United Kingdom
Biol Psychiatry 66:840-6. 2009..In this study, we investigated the effects of highlighting rewards versus highlighting punishments in the risky decision-making of euthymic individuals with bipolar disorder...
- Acute dietary tryptophan depletion impairs maintenance of "affective set" and delayed visual recognition in healthy volunteersJ S Rubinsztein
Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge CB2 2QQ, UK
Psychopharmacology (Berl) 154:319-26. 2001..The novel finding of impairment on a delayed visual pattern recognition task confirms and extends previous studies where selective effects on memory and learning have been found following acute tryptophan depletion...
- Short-term quetiapine treatment alters the use of reinforcement signals during risky decision-making and promotes the choice of negative expected values in healthy adult malesPhilippa L Rock
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, OX3 7JX, United Kingdom, and School of Psychology, Bangor University, Adeilad Brigantia, Bangor, Gwynedd, LL57 2AS, United Kingdom
J Neurosci 33:15588-95. 2013..These effects may be beneficial by correcting decision-making biases that feature in mood disorders. ..
- Reduced subjective response to acute ethanol administration among young men with a broad bipolar phenotypeSarah W Yip
Department of Psychiatry, University of Oxford, Oxford, UK
Neuropsychopharmacology 37:1808-15. 2012..These observations suggest that the dampened intoxication may contribute to the increased rates of alcohol misuse in young people at-risk for BD, and suggest possible shared etiological factors in the development of AUDs and BD...
- Ventral striatum/nucleus accumbens activation to smoking-related pictorial cues in smokers and nonsmokers: a functional magnetic resonance imaging studySean P David
Cancer Research United Kingdom General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Radcliffe Infirmary, UK
Biol Psychiatry 58:488-94. 2005..Converging evidence from several theories of the development of incentive-sensitization to smoking-related environmental stimuli suggests that the ventral striatum plays an important role in the processing of smoking-related cue reactivity...
- Deep brain stimulation of the subthalamic nucleus transiently enhances loss-chasing behaviour in patients with Parkinson's diseaseRobert D Rogers
Department of Psychiatry, University of Oxford, South Parks Road, Oxford, OX1 3UD, United Kingdom
Exp Neurol 231:181-9. 2011..Collectively, these results suggest that deep brain stimulation of the subthalamic nucleus can transiently alter the evaluation of accumulated losses during gambling episodes in idiopathic Parkinson's Disease...
- Attention to intentionHakwan C Lau
Department of Experimental Psychology, University of Oxford, Oxford, UK
Science 303:1208-10. 2004..Prefrontal activity, but not parietal activity, was more strongly coupled with activity in the pre-SMA. We conclude that activity in the pre-SMA reflects the representation of intention...
- Tryptophan depletion decreases the recognition of fear in female volunteersC J Harmer
University Department of Psychiatry, Warneford Hospital, Oxford, OX3 7JX, UK
Psychopharmacology (Berl) 167:411-7. 2003..The processing of other fear-relevant cues, such as facial expressions, has also been associated with amygdala function, but an effect of serotonin depletion on these processes has not been assessed...
- Willed action and attention to the selection of actionH C Lau
Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, UK
Neuroimage 21:1407-15. 2004..However, the presupplementary motor area (pre-SMA) may subserve this function as activity in this region was found to be tightly associated with the free selection of responses...
- The effects of a branched chain amino acid mixture supplemented with tryptophan on biochemical indices of neurotransmitter function and decision-makingA Scarna
University Department of Psychiatry, Warneford Hospital, Oxford, OX37JX, UK
Psychopharmacology (Berl) 179:761-8. 2005..However, the BCAA mixture also lowers the ratio of tryptophan (TRP) to BCAA which could impair brain serotonin function...
- Emotion regulation in psychopathyHelen Casey
Department of Psychiatry, University of Oxford, Warneford Hospital, Headington, Oxford OX3 7JX, UK
Biol Psychol 92:541-8. 2013....
- Adult and adolescent social reciprocity: experimental data from the Trust GameStefano R Belli
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, United Kingdom
J Adolesc 35:1341-9. 2012..Adults showed greater polarisation between coaxing and non-coaxing strategies than did adolescents. These data suggest that adults and adolescents may respond differently to periods of possible social rupture...
- Internet gamblers: a latent class analysis of their behaviours and health experiencesJoanne Lloyd
Department of Psychiatry, Warneford Hospital, Oxford University, UK
J Gambl Stud 26:387-99. 2010..Internet gamblers appear to be heterogeneous but composed of several subgroups, differing markedly on both demographic and clinical characteristics...
- Distinct portions of anterior cingulate cortex and medial prefrontal cortex are activated by reward processing in separable phases of decision-making cognitionRobert D Rogers
University Department of Psychiatry, Warneford Hospital, Oxford, United Kingdom
Biol Psychiatry 55:594-602. 2004....
- Altered memory and affective instability in prisoners assessed for dangerous and severe personality disorderTim Kirkpatrick
Oxford University Department of Psychiatry, Warneford Hospital, Oxford, OX3 7JX, UK
Br J Psychiatry Suppl 49:s20-6. 2007..No studies have compared memory functioning in high-risk prisoners with borderline personality disorder with similar prisoners with other personality disorders...
- Probabilistic learning and reversal deficits in patients with Parkinson's disease or frontal or temporal lobe lesions: possible adverse effects of dopaminergic medicationR Swainson
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, UK
Neuropsychologia 38:596-612. 2000....
- Decision-making in mania: a PET studyJ S Rubinsztein
Department of Psychiatry, University of Cambridge, Cambridge, UK
Brain 124:2550-63. 2001....
- Discrimination, reversal, and shift learning in Huntington's disease: mechanisms of impaired response selectionA D Lawrence
Department of Experimental Psychology, University of Cambridge, UK
Neuropsychologia 37:1359-74. 1999....
- Executive function in Tourette's syndrome and obsessive-compulsive disorderLaura H Watkins
MRC Cambridge Centre for Brain Repair, University of Cambridge, Cambridge, UK
Psychol Med 35:571-82. 2005....
- Manipulating the experienced onset of intention after action executionHakwan C Lau
University College London, UK
J Cogn Neurosci 19:81-90. 2007..A model, which is based on the mechanism of cue integration under the presence of noise, is offered to explain the results. The implications for the conscious control of spontaneous actions are discussed...
- Dissociating response selection and conflict in the medial frontal surfaceHakwan Lau
Functional Imaging Laboratory, Wellcome Department of Imaging Neuroscience, University College London, 12 Queen Square, London WC1N 3BG, UK
Neuroimage 29:446-51. 2006..The two clusters of activation do not overlap, and the peaks of them were about 30 mm apart. We conclude that the activity in the pre-SMA is related to the endogenous generation of action rather than response conflict...
- On measuring the perceived onsets of spontaneous actionsHakwan C Lau
Wellcome Department of Imaging Neuroscience, University College London, London WC1N 3BG, United Kingdom
J Neurosci 26:7265-71. 2006..We therefore argue that the timing method of Libet et al. (1983) is problematic, because the measuring process affects the neural representations of action and thus also the perceived onsets that the method is designed to measure...
- Neuropsychological investigations of the impulsive personality disordersRobert D Rogers
Psychol Med 33:1335-40. 2003