Glenn C Rodrigo

Summary

Affiliation: University of Leicester
Country: UK

Publications

  1. ncbi request reprint Role of mitochondrial re-energization and Ca2+ influx in reperfusion injury of metabolically inhibited cardiac myocytes
    Glenn C Rodrigo
    Department of Cell Physiology and Pharmacology, University of Leicester, PO Box 138, Leicester LE1 9HN, UK
    Cardiovasc Res 67:291-300. 2005
  2. ncbi request reprint Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes
    Glenn C Rodrigo
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Leicester, UK
    Am J Physiol Heart Circ Physiol 294:H524-31. 2008
  3. ncbi request reprint Diurnal variation in excitation-contraction coupling is lost in the adult spontaneously hypertensive rat heart
    Helen E Collins
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Leicester LE3 9QP, UK
    J Hypertens 31:1214-23. 2013
  4. ncbi request reprint Diazoxide causes early activation of cardiac sarcolemmal KATP channels during metabolic inhibition by an indirect mechanism
    Glenn C Rodrigo
    Department of Cell Physiology and Pharmacology, University of Leicester, PO Box 138, Leicester LE1 9HN, UK
    Cardiovasc Res 61:570-9. 2004
  5. doi request reprint Inotropic response of cardiac ventricular myocytes to beta-adrenergic stimulation with isoproterenol exhibits diurnal variation: involvement of nitric oxide
    Helen E Collins
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Leicester LE3 9QP, United Kingdom
    Circ Res 106:1244-52. 2010
  6. doi request reprint Phenylephrine preconditioning involves modulation of cardiac sarcolemmal K(ATP) current by PKC delta, AMPK and p38 MAPK
    Helen E Turrell
    Department of Cell Physiology and Pharmacology, Henry Wellcome Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK
    J Mol Cell Cardiol 51:370-80. 2011
  7. doi request reprint The time-of-day variation in vascular smooth muscle contractility depends on a nitric oxide signalling pathway
    M Denniff
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Leicester, UK
    J Mol Cell Cardiol 66:133-40. 2014

Collaborators

  • Martin Dickens
  • Helen E Turrell
  • Helen E Collins
  • M Denniff
  • Andrew Vanezis
  • Nilesh J Samani
  • Robert I Norman
  • Nicholas B Standen

Detail Information

Publications7

  1. ncbi request reprint Role of mitochondrial re-energization and Ca2+ influx in reperfusion injury of metabolically inhibited cardiac myocytes
    Glenn C Rodrigo
    Department of Cell Physiology and Pharmacology, University of Leicester, PO Box 138, Leicester LE1 9HN, UK
    Cardiovasc Res 67:291-300. 2005
    ..We used isolated myocytes to investigate the role of mitochondrial re-energization and Ca2+ influx during reperfusion on hypercontracture, loss of Ca2+ homeostasis and contractile function...
  2. ncbi request reprint Ischemic preconditioning of the whole heart confers protection on subsequently isolated ventricular myocytes
    Glenn C Rodrigo
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Leicester, UK
    Am J Physiol Heart Circ Physiol 294:H524-31. 2008
    ..The model should allow future studies in isolated cells of the protective mechanisms induced by true ischemia...
  3. ncbi request reprint Diurnal variation in excitation-contraction coupling is lost in the adult spontaneously hypertensive rat heart
    Helen E Collins
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Leicester LE3 9QP, UK
    J Hypertens 31:1214-23. 2013
    ..Pressure-induced hypertrophy is known to adversely affect the circadian clock in the heart and this study sets out to determine whether this alters the time-of-day variation in E-C coupling...
  4. ncbi request reprint Diazoxide causes early activation of cardiac sarcolemmal KATP channels during metabolic inhibition by an indirect mechanism
    Glenn C Rodrigo
    Department of Cell Physiology and Pharmacology, University of Leicester, PO Box 138, Leicester LE1 9HN, UK
    Cardiovasc Res 61:570-9. 2004
    ....
  5. doi request reprint Inotropic response of cardiac ventricular myocytes to beta-adrenergic stimulation with isoproterenol exhibits diurnal variation: involvement of nitric oxide
    Helen E Collins
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Leicester LE3 9QP, United Kingdom
    Circ Res 106:1244-52. 2010
    ..Although >10% of cardiac gene expression displays diurnal variations, little is known of their impact on excitation-contraction coupling...
  6. doi request reprint Phenylephrine preconditioning involves modulation of cardiac sarcolemmal K(ATP) current by PKC delta, AMPK and p38 MAPK
    Helen E Turrell
    Department of Cell Physiology and Pharmacology, Henry Wellcome Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK
    J Mol Cell Cardiol 51:370-80. 2011
    ..The increase in sarcK(ATP) current induced by phenylephrine preconditioning requires PKCĪ“, AMPK and p38 and may contribute to the observed improvement in contractile recovery...
  7. doi request reprint The time-of-day variation in vascular smooth muscle contractility depends on a nitric oxide signalling pathway
    M Denniff
    Department of Cardiovascular Sciences, University of Leicester, Glenfield General Hospital, Leicester, UK
    J Mol Cell Cardiol 66:133-40. 2014
    ..001), which translated to a 1.7-fold increase in total eNOS protein (P<0.05). The time-of-day variation in the response of mesenteric resistance vessels to phenylephrine and acetylcholine is dependent on NOS signalling...