Lynn Rochester

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. doi request reprint The nature of dual-task interference during gait in incident Parkinson's disease
    L Rochester
    Institute for Ageing and Health, Newcastle University, Clinical Ageing Research Unit, Campus for Ageing and Vitality, United Kingdom Electronic address
    Neuroscience 265:83-94. 2014
  2. doi request reprint The role of exergaming in Parkinson's disease rehabilitation: a systematic review of the evidence
    Gillian Barry
    Clinical Ageing Research Unit, Institute for Ageing and Health, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK
    J Neuroeng Rehabil 11:33. 2014
  3. pmc V-TIME: a treadmill training program augmented by virtual reality to decrease fall risk in older adults: study design of a randomized controlled trial
    Anat Mirelman
    Department of Neurology, Laboratory for Gait Analysis and Neurodynamics, Movement Disorders Unit, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv 64239, Israel
    BMC Neurol 13:15. 2013
  4. pmc Cholinergic dysfunction contributes to gait disturbance in early Parkinson's disease
    Lynn Rochester
    Institute for Ageing and Health, Newcastle University, Clinical Ageing Research Unit, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    Brain 135:2779-88. 2012
  5. doi request reprint Understanding the impact of deep brain stimulation on ambulatory activity in advanced Parkinson's disease
    Lynn Rochester
    Institute for Ageing and Health, Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    J Neurol 259:1081-6. 2012
  6. doi request reprint Targeting dopa-sensitive and dopa-resistant gait dysfunction in Parkinson's disease: selective responses to internal and external cues
    Lynn Rochester
    Clinical Ageing Research Unit, Newcastle University, Newcastle upon Tyne, United Kingdom
    Mov Disord 26:430-5. 2011
  7. doi request reprint Evidence for motor learning in Parkinson's disease: acquisition, automaticity and retention of cued gait performance after training with external rhythmical cues
    Lynn Rochester
    Institute for Ageing and Health, Newcastle University, UK Northumbria University, Newcastle, UK
    Brain Res 1319:103-11. 2010
  8. doi request reprint The effect of cueing therapy on single and dual-task gait in a drug naïve population of people with Parkinson's disease in northern Tanzania
    Lynn Rochester
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    Mov Disord 25:906-11. 2010
  9. doi request reprint Independent domains of gait in older adults and associated motor and nonmotor attributes: validation of a factor analysis approach
    Sue Lord
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne NE4 5PL
    J Gerontol A Biol Sci Med Sci 68:820-7. 2013
  10. ncbi request reprint The effect of external rhythmic cues (auditory and visual) on walking during a functional task in homes of people with Parkinson's disease
    Lynn Rochester
    Northumbria University, Newcastle, UK
    Arch Phys Med Rehabil 86:999-1006. 2005

Detail Information

Publications38

  1. doi request reprint The nature of dual-task interference during gait in incident Parkinson's disease
    L Rochester
    Institute for Ageing and Health, Newcastle University, Clinical Ageing Research Unit, Campus for Ageing and Vitality, United Kingdom Electronic address
    Neuroscience 265:83-94. 2014
    ..These findings inform an understanding of dual-task impairment in early PD and suggest that management should target postural control under dual-task conditions from the early stages. ..
  2. doi request reprint The role of exergaming in Parkinson's disease rehabilitation: a systematic review of the evidence
    Gillian Barry
    Clinical Ageing Research Unit, Institute for Ageing and Health, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, UK
    J Neuroeng Rehabil 11:33. 2014
    ..The use of commercial games may be too difficult for some people with PD and exergames tailored specifically to the rehabilitation needs and capabilities of people with PD are required for optimal efficacy, adherence and safety. ..
  3. pmc V-TIME: a treadmill training program augmented by virtual reality to decrease fall risk in older adults: study design of a randomized controlled trial
    Anat Mirelman
    Department of Neurology, Laboratory for Gait Analysis and Neurodynamics, Movement Disorders Unit, Tel Aviv Sourasky Medical Center, 6 Weizmann Street, Tel Aviv 64239, Israel
    BMC Neurol 13:15. 2013
    ..The proposed randomized controlled trial will evaluate the effects of treadmill training augmented with virtual reality on fall risk...
  4. pmc Cholinergic dysfunction contributes to gait disturbance in early Parkinson's disease
    Lynn Rochester
    Institute for Ageing and Health, Newcastle University, Clinical Ageing Research Unit, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    Brain 135:2779-88. 2012
    ..Our study provides new insights into underlying mechanisms of non-dopaminergic gait dysfunction, and may help to direct future therapeutic approaches...
  5. doi request reprint Understanding the impact of deep brain stimulation on ambulatory activity in advanced Parkinson's disease
    Lynn Rochester
    Institute for Ageing and Health, Clinical Ageing Research Unit, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    J Neurol 259:1081-6. 2012
    ..Novel measures derived from accelerometry provide a discrete measure of performance and allow closer interpretation of the impact of DBS-STN on real-world activity...
  6. doi request reprint Targeting dopa-sensitive and dopa-resistant gait dysfunction in Parkinson's disease: selective responses to internal and external cues
    Lynn Rochester
    Clinical Ageing Research Unit, Newcastle University, Newcastle upon Tyne, United Kingdom
    Mov Disord 26:430-5. 2011
    ..We explored the effect of two different cue strategies on gait characteristics in relation to their response to dopaminergic medications...
  7. doi request reprint Evidence for motor learning in Parkinson's disease: acquisition, automaticity and retention of cued gait performance after training with external rhythmical cues
    Lynn Rochester
    Institute for Ageing and Health, Newcastle University, UK Northumbria University, Newcastle, UK
    Brain Res 1319:103-11. 2010
    ..These results support the use of ERC to enhance motor learning in PD as defined by increased acquisition, automaticity and retention. They also highlight the potential for sustained improvement in walking and complex task performance...
  8. doi request reprint The effect of cueing therapy on single and dual-task gait in a drug naïve population of people with Parkinson's disease in northern Tanzania
    Lynn Rochester
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    Mov Disord 25:906-11. 2010
    ..This study also supports the feasibility of rehabilitation in PD in community environments in SSA, which may be applicable to other developing regions...
  9. doi request reprint Independent domains of gait in older adults and associated motor and nonmotor attributes: validation of a factor analysis approach
    Sue Lord
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne NE4 5PL
    J Gerontol A Biol Sci Med Sci 68:820-7. 2013
    ..However, there is no clear framework to guide selection of gait characteristics. This study developed and validated a model of gait in older adults based on a strong theoretical paradigm...
  10. ncbi request reprint The effect of external rhythmic cues (auditory and visual) on walking during a functional task in homes of people with Parkinson's disease
    Lynn Rochester
    Northumbria University, Newcastle, UK
    Arch Phys Med Rehabil 86:999-1006. 2005
    ..To evaluate (1) the influence of rhythmic cues on gait interference during a functional activity and (2) the relationship of clinical symptoms to gait interference...
  11. doi request reprint Walking speed during single and dual tasks in Parkinson's disease: which characteristics are important?
    Lynn Rochester
    School of Health, Community and Education Studies, Northumbria University, Newcastle, United Kingdom
    Mov Disord 23:2312-8. 2008
    ..Different patterns of characteristics for each outcome indicates the impact of cognitive demand and task complexity, providing cautious support for dual task speed and interference as valid proxy measures of cognitive demand in PD gait...
  12. ncbi request reprint Gait and gait-related activities and fatigue in Parkinson's disease: what is the relationship?
    Lynn Rochester
    School of Health, Community and Education Studies, Northumbria University, Newcastle upon Tyne, UK
    Disabil Rehabil 28:1365-71. 2006
    ..To explore the relationship between gait and gait-related activities and fatigue in Parkinson's disease (PD)...
  13. doi request reprint Gait variability in Parkinson's disease: an indicator of non-dopaminergic contributors to gait dysfunction?
    Sue Lord
    Clinical Ageing Research Unit, Campus for Ageing and Vitality, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, NE4 5PL, UK
    J Neurol 258:566-72. 2011
    ..Motor severity predicted DLS variability off medication, explaining 74% of variance. Different characteristics explain the two measures of gait variability, pointing to different control mechanisms...
  14. ncbi request reprint The effect of cues on gait variability--reducing the attentional cost of walking in people with Parkinson's disease
    Katherine Baker
    School of Health, Community and Education Studies, Northumbria University, Newcastle, UK
    Parkinsonism Relat Disord 14:314-20. 2008
    ..The reduction in gait variability of PD subjects with cues, suggests they may reduce the attentional cost of walking...
  15. doi request reprint Visual sampling during walking in people with Parkinson's disease and the influence of environment and dual-task
    Brook Galna
    Clinical Ageing Research Unit, Campus for Ageing and Vitality, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne NE4 5PL, UK
    Brain Res 1473:35-43. 2012
    ..Impaired visual sampling may contribute to the gait disorder in PD, especially when navigating through complex environments and when distracted...
  16. ncbi request reprint The immediate effect of attentional, auditory, and a combined cue strategy on gait during single and dual tasks in Parkinson's disease
    Katherine Baker
    School of Health, Community and Education Studies, Northumbria University, Newcastle, UK
    Arch Phys Med Rehabil 88:1593-600. 2007
    ..To compare the effect of rhythmic auditory and attentional cues, and a combination of both cues on gait, in people with Parkinson's disease (PD) during single and dual tasks...
  17. ncbi request reprint Attending to the task: interference effects of functional tasks on walking in Parkinson's disease and the roles of cognition, depression, fatigue, and balance
    Lynn Rochester
    Northumbria University, Newcastle, UK
    Arch Phys Med Rehabil 85:1578-85. 2004
    ..To evaluate the interference effects on walking of functional activities in the home in people with Parkinson's disease (PD) and the contribution of clinical symptoms to disturbance of gait...
  18. doi request reprint Short latency afferent inhibition: a biomarker for mild cognitive impairment in Parkinson's disease?
    Alison J Yarnall
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK
    Mov Disord 28:1285-8. 2013
    ..Mild cognitive impairment in Parkinson's disease (PD) is common and predicts those at risk of dementia. Cholinergic dysfunction may contribute to its pathophysiology and can be assessed using short latency afferent inhibition...
  19. doi request reprint Mild depressive symptoms are associated with gait impairment in early Parkinson's disease
    Sue Lord
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    Mov Disord 28:634-9. 2013
    ..Depression may be a marker for degeneration in nondopaminergic systems in early PD and influence mechanisms of gait disturbance. © 2013 Movement Disorder Society...
  20. doi request reprint Dorsal rather than ventral visual pathways discriminate freezing status in Parkinson's disease
    Sue Lord
    Institute for Ageing and Health, Newcastle University, Clinical Ageing Research Unit, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, UK
    Parkinsonism Relat Disord 18:1094-6. 2012
    ..Although visuospatial deficits have been linked with freezing of gait (FOG) in Parkinson's disease (PD), the specific effects of dorsal and ventral visual pathway dysfunction on FOG is not well understood...
  21. doi request reprint Towards measurement of the Healthy Ageing Phenotype in lifestyle-based intervention studies
    Jose Lara
    Human Nutrition Research Centre, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK
    Maturitas 76:189-99. 2013
    ....
  22. ncbi request reprint Concurrent validity of accelerometry to measure gait in Parkinsons Disease
    Sue Lord
    Northumbria University, Newcastle, UK
    Gait Posture 27:357-9. 2008
    ..74-0.94, p< or =0.05). Mean score differences between the two instruments were greatest for step frequency for both PD and comparisons. The VAM is useful for objective gait measurement in the home and community...
  23. doi request reprint Ambulatory activity in incident Parkinson's: more than meets the eye?
    Sue Lord
    Clinical Ageing Research Unit, Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, NE4 5PL, UK
    J Neurol 260:2964-72. 2013
    ..A focus on increasing general ambulatory activity and exercise from the outset is recommended...
  24. doi request reprint Is gait variability reliable in older adults and Parkinson's disease? Towards an optimal testing protocol
    Brook Galna
    Institute for Ageing and Health, Clinical Ageing Research Unit, Newcastle University, NE4 5PL, United Kingdom
    Gait Posture 37:580-5. 2013
    ..This study evaluates the impact of testing protocol and pathology on the reliability of gait variability...
  25. pmc Physical activity, sedentary behaviour and metabolic control following stroke: a cross-sectional and longitudinal study
    Sarah A Moore
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    PLoS ONE 8:e55263. 2013
    ..We assessed physical activity and sedentary behaviour at three time points following stroke compared to a healthy control group...
  26. doi request reprint Exploring patterns of daily physical and sedentary behaviour in community-dwelling older adults
    Sue Lord
    Institute for Ageing and Health, Newcastle University, Clinical Ageing Research Unit, Campus for Ageing and Vitality, Newcastle upon Tyne, UK
    Age Ageing 40:205-10. 2011
    ..This study quantified activity and sedentary behaviour in older, community-dwelling adults...
  27. doi request reprint Community ambulation in older adults: which internal characteristics are important?
    Susan E Lord
    Department of Medicine, University of Otago, Wellington, New Zealand
    Arch Phys Med Rehabil 91:378-83. 2010
    ..To examine the internal characteristics of older adults independent in community ambulation to gain further understanding of the skills required for its successful execution...
  28. doi request reprint Executive dysfunction and attention contribute to gait interference in 'off' state Parkinson's Disease
    Sue Lord
    Department of Medicine, University of Otago Wellington, New Zealand
    Gait Posture 31:169-74. 2010
    ..Whilst both contribute to functional gait, they are used selectively to optimise performance for different conditions and to meet complex task requirements...
  29. doi request reprint Accuracy of the Microsoft Kinect sensor for measuring movement in people with Parkinson's disease
    Brook Galna
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    Gait Posture 39:1062-8. 2014
    ..The purpose of this study was to establish the accuracy of the Kinect in measuring clinically relevant movements in people with PD...
  30. doi request reprint Gait impairment precedes clinical symptoms in spinocerebellar ataxia type 6
    Lynn Rochester
    Institute for Ageing and Health, Clinical Ageing Research Unit, Newcastle University, Newcastle upon Tyne, United Kingdom
    Mov Disord 29:252-5. 2014
    ..Gait ataxia is a prominent feature causing substantial disability. Understanding the evolution of the gait disturbance is a key step in developing treatment strategies...
  31. doi request reprint The interplay of cholinergic function, attention, and falls in Parkinson's disease
    Alison Yarnall
    Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, United Kingdom
    Mov Disord 26:2496-503. 2011
    ..It is therefore feasible that cognition (namely, attention), visual hallucinations, falls, and gait are subserved by acetylcholine, and this is further explored in this clinically orientated review...
  32. pmc Are behavioral interventions effective in increasing physical activity at 12 to 36 months in adults aged 55 to 70 years? A systematic review and meta-analysis
    Nicola Hobbs
    Institute of Health and Society, Newcastle University, Baddiley Clark building, Richardson Road, Newcastle upon Tyne NE2 4AX, UK
    BMC Med 11:75. 2013
    ..This systematic review adheres to a registered protocol (PROSPERO CRD42011001459)...
  33. doi request reprint Discrete gait characteristics are associated with m.3243A>G and m.8344A>G variants of mitochondrial disease and its pathological consequences
    Brook Galna
    Clinical Ageing Research Unit, Campus for Ageing and Vitality, Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK
    J Neurol 261:73-82. 2014
    ..Discrete gait characteristics may help describe functional deficits in mitochondrial disease, enhance measures of disease severity and pathology, and could be used to document treatment effects of novel therapies. ..
  34. doi request reprint The measurement of visual sampling during real-world activity in Parkinson's disease and healthy controls: a structured literature review
    Samuel Stuart
    Institute for Ageing and Health, Clinical Ageing Research Unit, Newcastle University, United Kingdom
    J Neurosci Methods 222:175-88. 2014
    ..The approach to the objective measurement of eye movements varies with respect to instrumentation, testing protocols, and mediating factors that may influence visual sampling...
  35. doi request reprint Moving forward on gait measurement: toward a more refined approach
    Sue Lord
    Institute for Ageing and Health, Clinical Ageing Research Unit, Newcastle University, United Kingdom
    Mov Disord 28:1534-43. 2013
    ..A structured approach to measurement is urgently required to fully realise the contribution gait can make to our understanding of neurodegenerative disease...
  36. doi request reprint Neurorehabilitation in Parkinson disease
    Neil Archibald
    Clinical Ageing Research Unit, Newcastle University, Newcastle upon Tyne, UK
    Handb Clin Neurol 110:435-42. 2013
    ..This chapter will review the current evidence base for neurorehabilitation in PD and discuss the challenges of service provision within healthcare systems...
  37. doi request reprint Gait variability in older adults: a structured review of testing protocol and clinimetric properties
    Sue Lord
    Institute for Ageing and Health, Newcastle University, UK
    Gait Posture 34:443-50. 2011
    ..Further research is required to standardise testing procedures and establish reliability, responsiveness and validity for confident use of gait variability as a robust measure...
  38. doi request reprint Mild cognitive impairment in Parkinson's disease
    Alison Jane Yarnall
    Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, Tyne and Wear NE4 5PL, UK
    Age Ageing 42:567-76. 2013
    ..Management includes screening for the disorder, excluding treatable causes of cognitive decline and cautious use of dopamine agonists and medications such as anticholinergics...