Stuart M Robinson
Affiliation: University of Newcastle
- The potential contribution of tumour-related factors to the development of FOLFOX-induced sinusoidal obstruction syndromeS M Robinson
1 Department of HPB Surgery, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK 2 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK
Br J Cancer 109:2396-403. 2013..The aim of this study was to assess the contribution of tumour-related factors to the development of FOLFOX-induced liver injury...
- An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injuryStuart M Robinson
Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
HPB (Oxford) 15:581-7. 2013..The aim of this study was to determine how the expression of genes involved in the transport and metabolism of FOLFOX chemotherapy impacts on tissue injury in a murine model of CLM...
- Pathogenesis of FOLFOX induced sinusoidal obstruction syndrome in a murine chemotherapy modelS M Robinson
Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
J Hepatol 59:318-26. 2013..The aim of this project was to establish a rodent model which could be utilised to investigate mechanisms underlying SOS to aid the development of therapeutic strategies...
- Metastatic lymph node ratio as an important prognostic factor in pancreatic ductal adenocarcinomaS M Robinson
Department of HPB Surgery, Freeman Hospital, Newcastle upon Tyne NE7 7DN, UK
Eur J Surg Oncol 38:333-9. 2012..The aim of this study was to identify the histological variables best able to predict long-term survival in these patients...
- Chemotherapy-associated liver injury in patients with colorectal liver metastases: a systematic review and meta-analysisStuart M Robinson
Department of HPB Surgery, Freeman Hospital, Newcastle upon Tyne, UK
Ann Surg Oncol 19:4287-99. 2012..The aim of this review was to determine the pathological effect of specific chemotherapy regimens on the hepatic parenchyma as well as on surgical morbidity, mortality and overall survival...
- Inadvertent surgical resection of soft tissue sarcomasM Venkatesan
Department of Orthopaedics, University Hospitals of Leicester, Infirmary Square, Leicester, LE1 5WW, UK
Eur J Surg Oncol 38:346-51. 2012..Despite these guidelines inadvertent excisions of soft tissue sarcomas continue to occur with alarming frequency, potentially compromising patient outcomes...
- N-acetylcysteine administration does not improve patient outcome after liver resectionStuart M Robinson
Department of HPB and Transplant Surgery, Freeman Hospital, Newcastle upon Tyne, UK
HPB (Oxford) 15:457-62. 2013..The generation of reactive oxygen species (ROS) as a result of hepatic ischaemia/reperfusion (I/R) injury can result in hepatocellular injury. Experimental evidence suggests that N-acetylcysteine may ameliorate ROS-mediated liver injury...
- Laparoscopic splenic biopsy--porcine to human studies--using a fibrin sealant techniqueKei Yiu Douglas Hui
Department of Hepatopancreatobiliary and Transplantation Surgery, The Freeman Hospital, Newcastle upon Tyne, Tyne and Wear, UK
Surg Laparosc Endosc Percutan Tech 23:e54-6. 2013..The aim of this study was to explore the feasibility of performing laparoscopic splenic biopsies using a fibrin sealant in pigs and then to translate this technique into the clinical setting...
- Laparoscopic liver resection: is there a learning curve?Stuart M Robinson
Department of Hepatobiliary and Transplant Surgery, The Freeman Hospital, Newcastle upon Tyne, UK
Dig Surg 29:62-9. 2012..However, it is critical that the laparoscopic approach does not compromise the technical quality of the liver resection. The aim of this paper was to review the learning curve of LLR in a specialist HPB unit...
- Role of nuclear factor kappaB in liver health and diseaseStuart M Robinson
Cell Signalling Group, Institute of Cellular Medicine, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
Clin Sci (Lond) 118:691-705. 2010..We explore the weaknesses of the experimental approaches to date and suggest that further work is needed to investigate in detail the discreet functions of each of the Rel subunits in liver physiology and disease...