Research Topics
| Nicholas P RobinsonSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
Extrachromosomal element capture and the evolution of multiple replication origins in archaeal chromosomesNicholas P Robinson
Medical Research Council Cancer Cell Unit, Hutchison Medical Research Council Research Center, Hills Road, Cambridge CB2 0XZ, United Kingdom
Proc Natl Acad Sci U S A 104:5806-11. 2007....
Identification of two origins of replication in the single chromosome of the archaeon Sulfolobus solfataricusNicholas P Robinson
Medical Research Council Cancer Cell Unit, Hutchison MRC Research Centre, Hills Road, Cambridge CB2 2XZ, United Kingdom
Cell 116:25-38. 2004..These data, in conjunction with an analysis of the levels of the three Orc1/Cdc6 proteins in different growth phases and cell cycle stages, lead us to propose a model for the roles for these proteins in modulating origin activity...
Origins of DNA replication in the three domains of lifeNicholas P Robinson
MRC Cancer Cell Unit, Hutchison MRC Research Centre, Hills Road, Cambridge, UK
FEBS J 272:3757-66. 2005..Furthermore, although there are mechanistic parallels, even within a given domain of life, the way origins of replication are defined shows remarkable variation...
Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomesColin Conway
Wellcome Centre for Molecular Parasitology, University of Glasgow, Anderson College, 56 Dumbarton Road, Glasgow, G11 6NU, Scotland, United Kingdom
J Biol Chem 277:21269-77. 2002..The absence of Ku and the consequent great shortening of telomeres had no detectable influence either on the rate of VSG switching or on the silencing of the telomeric promoters of the VSG subset that is expressed in the tsetse fly...
Inactivation of Mre11 does not affect VSG gene duplication mediated by homologous recombination in Trypanosoma bruceiNicholas P Robinson
Wellcome Centre for Molecular Parasitology, University of Glasgow, Anderson College, 56 Dumbarton Road, Glasgow G11 6NU, Scotland, United Kingdom
J Biol Chem 277:26185-93. 2002..Mre11 inactivation appears not to affect VSG gene switching during antigenic variation of a laboratory strain, which is perhaps surprising given the importance of homologous recombination during this process...
Sister chromatid junctions in the hyperthermophilic archaeon Sulfolobus solfataricusNicholas P Robinson
Medical Research Council Cancer Cell Unit, Hutchison MRC Research Centre, Cambridge, UK
EMBO J 26:816-24. 2007....
